scholarly journals Holistic Analysis of Cytokine and Cytokine Storm Researches in Scientific Literature: A Bibliometric Study of the Global Publications between 1980 and 2018

Author(s):  
Mustafa Şahin ◽  
Engin Şenel

Aim: Bibliometrics has been used for assessing and predicting trends in macro-health science and medical systems, especially in the field of cancer. Bibliometric and scientometric studies in the field of cytokines may guide further research in this field. Cytokines in particular cytokine storm has recently started to be highly discussed and studied in global viral infections. In the SARS-CoV-2 pandemic, cytokine storm was seen in many patients. In this study we want to present to perform bibliometric analysis of articles on cytokine and cytokine storm published in the academic literature during 1980 to 2018. Methods: The bibliometric analysis was performed using the Thomson Reuters Web of Science database. Results: A total of 232,606 articles were retrieved, 82.52% of which were original articles. The United States was the leading country by total publication number (n=84,426, 36.29%), followed by Japan (n= 21,983, 9.45%) produced the most literature on cytokine. Among the institutions identified, Harvard University (USA) contributed the most articles on cytokine. All authors and institutions in the top 10 contributor’s lists were from the developed countries. Conclusions: Researchers from the developing and least-developed countries should be encouraged to perform novel studies on cytokine. Cytokine studies are associated with the pathology and physiological variability of many diseases and may have beneficial results in the medical field. Cytokine and cytokine storm studies may be particularly useful in identifying the pathogenesis of global viral infections such as SARS-CoV-2, evaluating and developing new treatment strategies.

2019 ◽  
Vol 18 ◽  
pp. 117693511985262 ◽  
Author(s):  
Yılmaz Baş ◽  
Engin Şenel

Background: Bibliometrics has been used for assessing and predicting trends in macro-health science and medical systems, especially in the field of cancer. Bibliometric and scientometric studies in the field of programmed cell death 1/programmed cell death 1 ligand 1 (PD-1/PD-L1) may guide further research in this field. Objective: To perform bibliometric analysis of articles on PD-1 and PD-L1 published in the academic literature during 1975 to 2017. Method: The bibliometric analysis was performed using the Thomson Reuters Web of Science database. Results: A total of 23 813 articles were retrieved, 73.52% of which were original articles. The United States was the leading country by total publication number (n = 10 897, 10.91%), followed by China (10.54%), and produced the most literature on PD-1/PD-L1 (164.65 articles). Among the institutions identified, Harvard University (USA) contributed the most articles on PD-1/PD-L1. Conclusions: All authors and institutions in the top 10 contributor’s lists were from the developed countries. Researchers from the developing and least-developed countries should be encouraged to perform novel studies on PD-1 and PD-L1.


Author(s):  
Jingli Chen ◽  
Xin Li ◽  
Yifan Jia ◽  
Zhongyuan Xia ◽  
Jishi Ye

In the past 16 years, research on mitophagy has increasingly expanded to a wider range of subjects. Therefore, comprehensively analyzing the relevant progress and development trends on mitophagy research requires specific methods. To assess the hotspots, directions, and quality of results in this field worldwide, we used multiple tools to examine research progress and growing trends in research on the matter during the last 16 years (from 2005 to 2020). We also compared the quantity and quality of the literature records on mitophagy published by research institutions in China and other developed countries, reviewed China’s contribution, and examined the gap between China and these developed countries. According to the results of our bibliometric analysis, the United States and its research institutes published the most papers. We identified cell biology as the most commonly researched subject on mitophagy and AUTOPHAGY as the most popular journal for research on mitophagy. We also listed the most cited documents from around the world and China. With gradually increased funding, China is progressively becoming prominent in the field of mitophagy; nevertheless, the gap between her and major countries in the world must be closed.


2020 ◽  
Author(s):  
Mingzhou Gao ◽  
Hui SUN ◽  
Changlong ZHANG ◽  
Dongmei GAO ◽  
Mingqi QIAO

Abstract Background The global incidence of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) is increasing, with increasing suicide reports. However, the bibliometric analysis of global research on PMS and PMDD is rare. We aimed to evaluate the global scientific output of research on PMS and PMDD and to explore their research hotspots and frontiers from 1945 to 2018 using a bibliometric analysis methodology.Methods Articles with research on PMS and PMDD between 1945 and 2018 were retrieved from the Web of Science Core Collection (WoSCC). We used the bibliometric method, CiteSpace V and VOSviewer to analyze publication years, journals, countries, institutions, authors, research hotspots, and trends. We plotted the reference co-citation network, and we used keywords to analyze the research hot spots and trends.Results We identified 2,833 publications on PMS and PMDD research from 1945 to 2018, and the annual publication number increased with time, with fluctuations. Psychoneuroendocrinology published the highest number of articles. The United States ranked the highest among the countries with the most publications, and the leading institute was UNIV PENN. Keyword and reference analysis indicated that the menstrual cycle, depression and ovarian hormones were the research hotspots, whereas prevalence, systematic review, anxiety and depression and young women were the research frontiers.Conclusions We depicted overall research on PMS and PMDD by a bibliometric analysis methodology. Prevalence and impact in young women , systematic review evaluations of risk factors, and the association of anxiety and depression with menstrual cycle phases are the latest research frontiers that will pioneer the direction of research in the next few years.


2008 ◽  
Vol 1 (1) ◽  
Author(s):  
Caf Dowlah

The Generalized System of Preferences (GSP)—a system of differential and favorable trade arrangements toward less developed countries, adopted by the General Agreement on Tariff and Trade (GATT)—has been around since the early 1970s. A primary objective of these schemes has been to promote industrialization and economic growth in less developed countries through trade rather than aid. The outcome of such programs has, however, been mixed. This paper identifies some of the underlying political and economic dynamics which led to the dismal performance of the GSP schemes of the United States in respect to the industrialization and economic growth of the Least Developed Countries (LDCs). The paper suggests that the effectiveness of GSP schemes could be significantly improved if they were brought under the binding WTO rules, if greater resources were directed to removing supply constraints in the LDCs, and if developed countries granted unwavering market access to LDC exports.


2021 ◽  
Author(s):  
Harun Bal ◽  
Berk Palandökenlier

Whether the Dutch Disease thesis, which is one of the best-known economic explanations on this subject, which puts forward the thesis that countries rich in natural resources can have negative effects on long-term economic growth, directly or indirectly, depending on the way they are used, is valid or not. tried to be demonstrated. The Dutch disease thesis is one of the main explanations for resource misfortune, emphasizing the negative effects of resource abundance on the national economy in countries with rich resource endowments and pointing to a paradox that economic conditions will be better in countries that do not have relatively little (or scarce) natural resources. is happening. Therefore, in our study, it is aimed to investigate whether resource richness causes an economic recession or not, especially for developed countries by considering indirect transmission channels. In this context, 11 developed countries such as Netherlands, Norway, Ireland, Germany, New Zealand, the United States of America, Canada, Australia, Poland, the United Kingdom, and Denmark, between 1990 and 2019, are based on the experiences of developed countries, which are especially rich in different sources of Dutch Disease syndrome. The country has been researched with static and dynamic panel analysis methods. As a result of the estimation, findings were found that the Dutch Disease was partially valid in terms of developed country samples throughout the sample period considered.


2021 ◽  
Vol 13 (17) ◽  
pp. 9673
Author(s):  
Feng Han ◽  
Zhangcong Feng ◽  
Chao Wang ◽  
Nujie Yang ◽  
Dong Yang ◽  
...  

Although industrial activity has brought about rapid economic growth, it also faces the dual challenges of resource constraints and environmental pressure. Industrial ecology (IE) and ecological modernization (EM) are two theories regarding the conceptualization and implementation of sustainable development that emerged from the natural and social sciences, respectively. Over the past three decades, scholars have conducted copious amounts of theoretical and applied research on IE and EM, but comparative studies from an interdisciplinary perspective on the relationship between the two remain relatively rare. On the basis of a bibliometric analysis, this study offers a comprehensive examination of the background, theoretical connotations, and main content of IE and EM, also exploring the role of both theoretical perspectives in the promotion of sustainable industrial development. The findings are fourfold: (1) the research on IE and EM has been increasing year by year, particularly in the past decade; (2) the research is mostly concentrated in developed countries such as the United States and European Union member nations, and contributions from China have increased significantly in recent years; (3) IE has a broader research community than EM and has evolved clearer and more specific research contents and methods; and (4) IE, which analyzes the problems of specific industrial systems, and EM, which constitutes a higher-level institutional policy design, exhibit a trend of cross-fertilization. This study provides a reference for building a more systematic and comprehensive theoretical system of ecological transformation and discusses the future research directions in this field.


2021 ◽  
Vol 3 (4) ◽  
pp. 350-355
Author(s):  
Uğur Küçük ◽  
◽  
Sevil Alkan ◽  
Cemile Uyar ◽  
◽  
...  

Introduction: Although infective endocarditis (IE) is rare disease, this disease has importance due to its high morbidity and mortality rates. The exact incidence is not known as it is not a reportable disease. Unlike developed countries, the disease affects the young more than the elderly in developing countries. Most of the time, the diagnosis cannot be made at the first examination and the disease is often overlooked. In order to reduce the mortality and morbidity of this disease, it is important to quickly recognize the disease by following current diagnosis and treatment methods, to identify the causative agent and to treat accordingly. Both the epidemiology and the management of IE are changing due to medical advances. This situation may also be reflected in scientific publications. We aimed to analyze the global researches on IE. Material and methods: The Scopus database was searched for bibliometric analysis without selecting document type. Data were retrieved for the time period January 1, 1940 and Semptember 26, 2021, containing the keywords " Infective’’ and’’endocarditis " in their title. Results: 7911 publications were included in the study. The first publication was made in the year 1891. Most of the publications were research articles [n=5784 (73.11%)] and were from the United States of America (USA) [n =1622 (20.50%)]. Japan, France, United Kingdom and Spain were also in the top 5 publishing countries on IE. Conclusions: Infective endocarditis is still an important reason of mortality, and there are many unanswered questions about the managament and preventation of this disease. This situation reflected the scientific publications. Since this is a global problem, not just some developed countries involved in the IE research, also more countries should be encouraged to participate the studies on IE.


2011 ◽  
Vol 16 (4) ◽  
pp. 605-624 ◽  
Author(s):  
Angus C. Chu

Can a transfer of wealth from the United States to the least developed countries be Pareto improving? We analyze this question in an open-economy R&D-based growth model, in which the high-income (low-income) country produces innovative (homogeneous) goods. We find that wealth redistribution to the low-income country simultaneously reduces global inequality and increases economic growth through an increase in labor supply in the high-income country. Given that the market equilibrium of R&D-based growth models is usually inefficient due to R&D externalities, the wealth redistribution may lead to a Pareto improvement, which occurs if the discount rate is sufficiently low or R&D productivity is sufficiently high.


2016 ◽  
Vol 2 (1) ◽  
pp. 155-164
Author(s):  
Mihir Kanade

When Kenya’s President, Uhuru Kenyatta, opened the first ever World Trade Organisation (WTO) Ministerial Conference to be held on African soil, he knew that the Doha Development Agenda (DDA)1 ceremoniously agreed upon in 2001, and of which his country had been an ardent promoter, would be put under the guillotine. So much was made abundantly clear by Michael Froman, the United States of America Trade Representative (USTR), in an op-ed published in the Financial Times just two days prior to the Conference. Froman argued that "Doha was designed in a different era, for a different era, and much has changed since", and that "it is time for the world to free itself of the strictures of Doha’, before concluding presciently that ‘Nairobi will mark the end of an era".  The Conference of 2015 closed with a Ministerial Declaration and the ‘Nairobi Package’ comprising a series of six Ministerial Decisions on agriculture, cotton and issues related to least developed countries (LDCs). WTO’s Director-General, Roberto Azevêdo, concluded with optimism that, similar to two years ago in Bali, the WTO had once again delivered ‘major, multilaterally-negotiated outcomes’ at Nairobi. All these things will be analyzed in the following lines. 


2019 ◽  
Vol 37 (6) ◽  
pp. 474-480
Author(s):  
Chia-Jen Liu ◽  
Te-Chun Yeh ◽  
Ming-Hsuan Hsieh ◽  
Lin-Chung Woung ◽  
Sheng-Jean Huang ◽  
...  

Background: In recent decades, issues related to end-of-life care and advance care planning (ACP) have attracted popular attention. Advance care planning has been broadly discussed as one of the potential solutions to protect a patient’s rights, autonomy, and dignity at the end of life. To better understand publishing on this topic, we conducted this study to demonstrate the worldwide research productivity, trends, and citations of ACP in the past 3 decades by bibliometric analysis. Methods: Articles published on ACP were retrieved from the Web of Science Core Collection database, and the subject terms included “advance directive,” or “advance care planning.” Results: Overall, 2126 publications on ACP were retrieved until January 22, 2019. North America, Western Europe, and Australia were the most productive regions. The top 15 countries published 95.9% of the total number of articles. The United States accounted for approximately three-fifths (61.0%) of all publications. When adjusted for population size, Australia had the highest number of articles per million persons (6.64), followed by the Netherlands (6.14) and Belgium (4.61). The most productive authors were Sudore (n = 37), Deliens (n = 29), and Green (n = 24). Conclusions: The current study revealed that research in terms of publications on ACP has rapidly increased over the past 3 decades. Developed countries, especially the United States, were more concerned with the ACP research field than developing countries were.


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