scholarly journals Telomere dynamics in the first year of life, but not later in life, predict lifespan in a wild bird

2021 ◽  
Author(s):  
Elizabeth Sheldon ◽  
Justin Eastwood ◽  
Niki Teunissen ◽  
Michael Roast ◽  
Marie Fan ◽  
...  
Keyword(s):  
Telomere Length ◽  
Wild Bird ◽  
First Year ◽  
Data Set ◽  
Telomere Shortening ◽  
Total Life Expectancy ◽  
Absolute Length ◽  
First Year Of Life ◽  
The Relationship ◽  
Total Life

Telomeres are protective, nucleoprotein structures at the end of chromosomes that have been associated with lifespan across taxa. However, the extent to which these associations can be attributed to absolute length versus the rate of telomere shortening prior to sampling remains unresolved. In a longitudinal study, we examined the relationship between lifespan, telomere length and the rate of telomere shortening in wild, purple-crowned fairy-wrens (Malurus coronatus coronatus). To this end, we measured telomere length using qPCR in the blood of 59 individuals sampled as nestling and 4-14 months thereafter, and in 150 individuals sampled on average three times across adulthood. We applied within-subject centering analyses to simultaneously test for associations between lifespan and average telomere length and telomere shortening. We reveal that the rate of telomere shortening in the first year of life predicted lifespan, with individuals with faster shortening rates living less long. We also report a trend for an effect of telomere length in the first year of life on lifespan, independent of telomere shortening. In contrast, in adulthood neither telomere shortening, nor telomere length predicted lifespan, despite a considerably larger data set. Our results suggest that telomere length measured very early in life (during development) and longitudinal assessments of telomere shortening during the first year of life constitute more useful biomarkers of total life expectancy than either telomere length measured after development, or telomere shortening later in adulthood.

Factors Associated with Maternal Opinion of Infant Development—Clues to the Vulnerable Child?

PEDIATRICS ◽  
1982 ◽  
Vol 69 (5) ◽  
pp. 537-543
Author(s):  
Marie C. McCormick ◽  
Sam Shapiro ◽  
Barbara Starfield
Keyword(s):  
Birth Weight ◽  
Infant Development ◽  
Infant Health ◽  
Subsequent Development ◽  
First Year ◽  
Factors Associated ◽  
Slow Development ◽  
First Year Of Life ◽  
Relationship Of ◽  
The Relationship

A mother's expectations about the development of her infant have been found to be a strong determinant of child development, but little is known about the factors that may affect maternal assessment of development. In this study, the relationship of the mother's opinion of the development of her infant with several sociodemographic, antenatal, intrapartum, and infant health variables was examined for a large sample of 1-year-old infants for whom gross motor observations were also obtained at the time of the interview. Among those observed to be developing at an appropriate rate, 4.0% were perceived by their mothers as developing more slowly than the mothers considered normal; among infants developing more slowly, 28.6% were considered to be developing slowly by their mothers. In both groups, the major determinants of maternal opinion of slow development concerned the infant's health: low birth weight, congenital anomalies regardless of severity, hospitalization during the first year of life, and high ambulatory care use. These results indicate that maternal perception of infant development may not reflect the infant's level, but past or present illness, and raise questions about the influence of infant health on maternal-infant interactions and the effect of such interactions on subsequent development in the child.

scholarly journals The influence of pre-recruitment growth on subsequent growth and age at first spawning in Atlantic herring (Clupea harengus L.)

2003 ◽  
Vol 60 (5) ◽  
pp. 1103-1113 ◽  
Author(s):  
Deirdre Brophy ◽  
Bret S Danilowicz
Keyword(s):  
Clupea Harengus ◽  
First Year ◽  
Fish Length ◽  
Subsequent Growth ◽  
Differential Growth ◽  
Stock Biomass ◽  
Spawning Stock ◽  
Group Spawning ◽  
First Year Of Life ◽  
The Relationship

Abstract Calculation of the spawning stock biomass for fisheries management requires information on the numbers or proportions of fish in each age- or length-group that are mature each year. This study was conducted to determine the relationship between growth and age of first reproduction in herring stocks around Ireland. Measurements of otolith size at the onset of the first annulus (O1) were used to compare growth during the first year of life between 1-, 2-, and 3-group spawning herring collected from spawning grounds in the Celtic Sea over a period of 3 years. The 1-group spawning fish had significantly greater mean O1 measurements, and hence showed faster growth on average during the first year of life than 2- or 3-group spawning fish. Fish that exhibited slow growth during the first year were absent from the adult spawning population at age 1, but occurred at similar levels in the samples of 2- and 3-group spawning fish. Regression of O1 radius on fish length at capture showed that growth during the first year of life had a small but significant effect on subsequent growth up to age 3. The relationship between pre-recruitment growth and subsequent growth and age at first spawning has implications for recruitment patterns of juveniles from different nursery areas and for the lifetime fecundity of population components with differential growth.

scholarly journals Non-nutritive suck and voice onset time: Examining infant oromotor coordination

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250529
Author(s):  
Elizabeth Heller Murray ◽  
Joanna Lewis ◽  
Emily Zimmerman
Keyword(s):  
Vocal Tract ◽  
Voice Onset Time ◽  
Onset Time ◽  
Speech Development ◽  
Burst Duration ◽  
First Year ◽  
Term Infants ◽  
First Year Of Life ◽  
Future Work ◽  
The Relationship

The variability of a child’s voice onset time (VOT) decreases during development as they learn to coordinate upper vocal tract and laryngeal articulatory gestures. Yet, little is known about the relationship between VOT and other early motor tasks. The aims of this study were to evaluate the relationship between infant vocalization and another early oromotor task, non-nutritive suck (NNS). Twenty-five full-term infants (11 male, 14 female) completed this study. NNS was measured with a customized pacifier at 3 months to evaluate this early reflex. Measures of mean VOT and variability of VOT (measured via coefficient of variation) were collected from 12-month-old infants using a Language Environmental Analysis device. Variability of VOTs at 12 months was significantly related to NNS measures at 3-months. Increased VOT variability was primarily driven by increased NNS intraburst frequency and increased NNS burst duration. There were no relationships between average VOT or range of VOT and NNS measures. Findings from this pilot study indicate a relationship between NNS measures of intraburst frequency and burst duration and VOT variability. Infants with increased NNS intraburst frequency and NNS burst duration had increased VOT variability, suggesting a relationship between the development of VOT and NNS in the first year of life. Future work is needed to continue to examine the relationship between these early oromotor actions and to evaluate how this may impact later speech development.

scholarly journals Maternal Prenatal Microbiome and Infant’s Immune System at the Origins of the Development of Health and Disease

2021 ◽  
Author(s):  
Iván Enrique Naranjo Logroño ◽  
Leslie Gricel Cuzco Macías ◽  
Alison Tamara Ruiz Chico ◽  
Anthony Alfonso Naranjo Coronel
Keyword(s):  
Immune System ◽  
Randomized Clinical Trials ◽  
Human Microbiome ◽  
First Year ◽  
El Sistema ◽  
Health And Disease ◽  
Land Surfaces ◽  
First Year Of Life ◽  
Relationship Of ◽  
The Relationship

Introduction: The human microbiome refers to the presence of microorganisms that live with its host. Objective: To analyze the relationship between the maternal perinatal microbiome and the development of the infant’s immune system, at the origins of the development of health and disease. Methodology: A non-systematic bibliographic review was carried out, including those controlled and randomized clinical trials focused on the relationship of the prenatal maternal microbiome and the infant’s immune system. And all those works whose approach was different from the topic raised were excluded. Discussion: 20 min after birth, the microbiome of newborns by vaginal delivery resembles the microbiota of their mother’s vagina, while those born by caesarean section house microbial communities that are usually found in human skin. The acquisition of the microbiome continues during the first years of life, with a microbiome of the baby’s gastrointestinal tract beginning to resemble that of an adult from the first year of life. Conclusion: Bacteria are microorganisms that have managed to colonize the vast majority of land surfaces, showing great adaptability. The human being is not indifferent, and hypotheses have been raised that affirm his participation in the development of health and the onset of the disease. Keywords: microbiota, inmune system, infant nutritional physiological phenomena. RESUMEN Introducción: El microbioma humano se refiere a la presencia de microorganismos que conviven con su hospedero. Objetivo: Analizar la relación existente entre el microbioma materno perinatal y el desarrollo del sistema inmune del lactante, en los orígenes del desarrollo de la salud y enfermedad. Metodología: Se realizó una revisión bibliográfica no sistemática, donde se incluyeron aquellos ensayos clínicos controlados y randomizados enfocados en la relación del microbioma materno prenatal y el sistema inmune del lactante. Y se excluyeron todos aquellos trabajos cuyo enfoque fue diferente al tema planteado. Resultados: Se encontraron 61 fuentes bibliográficas, de las cuales se incluyeron 53 artículos que contenían la información relacionada al tema y publicados en los últimos 11 años. Discusión: 20 min después del nacimiento, el microbioma de los recién nacidos por parto vaginal se asemeja a la microbiota de la vagina de su madre, mientras que los nacidos por cesárea albergan comunidades microbianas que generalmente se encuentran en la piel humana. La adquisición del microbioma continúa durante los primeros años de vida, con un el microbioma del tracto gastrointestinal del bebé comienza a parecerse al de un adulto desde el primer año de vida. Conclusiones: Las bacterias, son microorganismos que han logrado colonizar la gran mayoría de las superficies terrestres, mostrando una gran capacidad de adaptación. El ser humano, no es indiferente, y se han planteado hipótesis que aseveran su participación en el desarrollo de la salud e inicio de la enfermedad. Palabras clave: microbiota, sistema inmunológico, fenómenos fisiológicos nutricionales del lactante.

scholarly journals Longitudinal Colonization With Streptococcus pneumoniae During the First Year of Life in a Healthy Newborn Cohort

2019 ◽  
Vol 9 (4) ◽  
pp. 442-448
Author(s):  
Sharon B Meropol ◽  
Michael R Jacobs ◽  
Kurt C Stange ◽  
Saralee Bajaksouzian ◽  
Robert A Bonomo
Keyword(s):  
Streptococcus Pneumoniae ◽  
First Year ◽  
Antibiotic Exposure ◽  
Academic Hospital ◽  
Antibiotic Resistant ◽  
Exposure Data ◽  
Pneumococcal Colonization ◽  
First Year Of Life ◽  
The Relationship

Abstract Background The objective of this study was to characterize longitudinal colonization with Streptococcus pneumoniae during the first year of life within a community newborn infant cohort, and assess the relationship between antibiotic exposure and colonization with antibiotic-resistant organisms. Methods During April 2013–February 2014, 326 infants were enrolled from an urban academic hospital well-baby nursery. At ages 4, 8, and 12 months, we collected antibiotic data, other exposure data, and nasopharyngeal cultures for pneumococcal isolation. Results Follow-up visits were completed for 211, 158, and 144 infants at ages 4, 8, and 12 months, respectively. By 12 months, 33% of infants attending the visits had ever been exposed to antibiotics, 67% if exposures to maternal antibiotics at birth are included. Pneumococci were isolated at 38/839 (4.5%) visits from 38 infants, including one 13-valent conjugate vaccine (PCV13) serotype (6A). There were 1 (0.3%), 15 (7%), 7 (4%), and 15 (10%) infants who were colonized at 0-, 4-, 8-, and 12-month visits, respectively. By age 12 months, at least 35 (11%) infants had ever been colonized. Sixteen isolates (42%) exhibited nonsusceptibility to at least 1 antibiotic. Infants with recent antibiotic exposure were not more likely to be colonized or to harbor nonsusceptible organisms. Conclusions Within a hospital birth cohort followed in the community, pneumococcal colonization and related antibiotic resistance were lower than previously reported, likely associated with PCV13 use. Antibiotic exposure was not associated with subsequent colonization with resistant isolates. The influence of other environmental factors needs further study.

scholarly journals The relationship between caregiver sensitivity and infant pain behaviors across the first year of life

Pain ◽  
2011 ◽  
Vol 152 (12) ◽  
pp. 2819-2826 ◽  
Author(s):  
Rebecca Pillai Riddell ◽  
Lauren Campbell ◽  
David B. Flora ◽  
Nicole Racine ◽  
Laila Din Osmun ◽  
...  
Keyword(s):  
First Year ◽  
Pain Behaviors ◽  
Infant Pain ◽  
First Year Of Life ◽  
The Relationship

scholarly journals 103 THE RELATIONSHIP BETWEEN NURSING PATTERN &, BREAST MILK INTAKE IN THE FIRST YEAR OF LIFE

1986 ◽  
Vol 20 (10) ◽  
pp. 1051-1051
Author(s):  
S M Imong ◽  
D A Jackson ◽  
M W Woolridge ◽  
R F Drewett ◽  
K Amatayakul
Keyword(s):  
Breast Milk ◽  
Milk Intake ◽  
First Year ◽  
First Year Of Life ◽  
The Relationship

The Relationship of Early Behaviour to Later Developmental Outcome for Preterm Children

1996 ◽  
Vol 19 (3) ◽  
pp. 517-532 ◽  
Author(s):  
Jaroslava Dittrichová ◽  
Václav Břicháček ◽  
František Mandys ◽  
Karel Paul ◽  
Daniela Sobotková ◽  
...  
Keyword(s):  
Social Environment ◽  
Preterm Infants ◽  
Gestational Age ◽  
Early Identification ◽  
Developmental Outcomes ◽  
First Year ◽  
The Social ◽  
First Year Of Life ◽  
Relationship Of ◽  
The Relationship

The present study aimed, first, to analyse in detail early sleep states in 21 preterm infants born before the 33rd week of gestational age and compare them with sleep states in 23 fullterm infants assessed at gestationally matched ages in the first six months. Second, to determine whether analyses of early sleep states in preterm infants may enable identification of infants with future developmental disabilities. In addition to evaluations of perinatal risk factors, neurological condition, psychological development, and social environment during the first year of life, examinations of psychological and neurological development and the assessment of the social environment at 3 and 9 years were carried out. Measures of perinatal status and sleep states up to the age of 40 weeks gestational age did not correlate with outcome measures at 3 and 9 years. However, the polygraphic measures of sleep states at 12 and 24 weeks corrected age, predicted the 3-year developmental outcomes. The complexity of these measures may contribute to their predictive validity for the outcomes at 3 years. Measures of the social environment at 3 and 9 years contributed significantly to the prediction of 9-year developmental outcomes. These results indicate that environmental factors may become more important with age. The detailed analysis of early sleep patterns may enable the early identification of infants who need special care and intervention.

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