scholarly journals SCIENTIFIC PERSPECTIVES OF STUDY OF THE CAUSAL-INVESTIGATION CONNECTION OF MICROBIOTES OF THE INTESTINE AND THE STATE OF THE NERVOUS SYSTEM

2018 ◽  
Vol 10 (3) ◽  
pp. 41-44
Author(s):  
N. V. Skripchenko ◽  
S. E. Ukraintsev ◽  
E. G. Makarova ◽  
E. Yu. Skripchenko
Keyword(s):  
Nervous System ◽  
Intestinal Microbiota ◽  
Analysis Data ◽  
Review Article ◽  
Direct Relevance ◽  
Modern Methods ◽  
Scientific Substantiation ◽  
Digestive Disorders ◽  
Functional Digestive Disorders ◽  
The Brain

The review article presents the scientific substantiation of the prospective direction of research of the intestinal microbiota and its role in the formation of various neurological pathologies. Reflected information about the enteral nervous system, which has direct relevance in the interaction between the brain and intestines. The study of the intestinal microbiota is currently carried out using modern methods of metagenomics, sequencing and bioinformation analysis. Data are presented on the formation of functional digestive disorders in children with altered intestinal microbiota and the ways of correction are determined.

scholarly journals COVID-19 survivors and neuropsychological issues: A way forward

2020 ◽  
Vol 24 (5) ◽  
Author(s):  
Muhammad Rafiq ◽  
Umaiza Bashir ◽  
Jamshed Hasnain
Keyword(s):  
Mental Health ◽  
Nervous System ◽  
Intensive Care ◽  
Literature Review ◽  
Respiratory Symptoms ◽  
Viral Infections ◽  
Treatment Plan ◽  
Review Article ◽  
Limited Data ◽  
The Brain

Background: This brief article focuses on highlighting the importance of possible neuropsychological manifestations among the Coronavirus Disease 19 (COVID-19) survivors. Studies have evidenced that like other Coronaviruses, COVID-19 is highly contagious and also responsible for the development of mild to severe respiratory symptoms. As COVID-19 is a recently emerged pandemic that has resulted in more than six hundred thousand deaths around the globe as of July 2020 and most of the researches has focused on the physical manifestations. Purpose: The purpose of this review article was to highlight the importance of COVID-19 infection in perspective to mental health in those patients who are survived. Methodology: For this purpose, an intensive literature review was conducted through different scientific search engines including PubMed, Google Scholars, Science Direct, etc. Results and Conclusion: There is very limited data available on manifestations including psychological and neuropsychological. Studies have shown that viral infections including viruses from Coronaviridae have been implicated in the nervous system including the brain. So, it is important to investigate the post-COVID-19 infection in neuropsychological aspects. Such studies will highlight the importance of post-COVID-19 complications and will also help in redesigning the treatment plan for mental health. Keywords: COVID-19, neuropsychological issues, mental health, Coronavirus Disease 19 Survivors, depression, anxiety, stress Citation: Rafiq M, Bashir U, Hasnain J. COVID-19 survivors and neuropsychological issues: A way forward. Anaesth. pain intensive care 2020;24(5):

Aspects of Neuroplasticity

2021 ◽  
pp. 9-23
Author(s):  
John Zerilli
Keyword(s):  
Nervous System ◽  
Synaptic Plasticity ◽  
Memory Consolidation ◽  
Direct Relevance ◽  
Different Types ◽  
Crossmodal Plasticity ◽  
Cortical Map ◽  
The Brain ◽  
Intrinsic Feature

The brain exhibits an impressive degree of plasticity, even as it ages. Plasticity is really an intrinsic feature of the nervous system, not an exceptional or occasional state. Neuroplasticity comprises a family of different types of plasticity. Of these, synaptic plasticity is perhaps the best-understood variety, and it plays an important role in cortical map reorganization and memory consolidation. Cortical map plasticity is of direct relevance to any discussion of modularity. There are two types of cortical map plasticity: intramodal (within a modality) and crossmodal. Crossmodal plasticity is likely to arise from the underlying supramodal (or “metamodal”) organization of the brain.

scholarly journals Observations on the anatomy, physiology, and degenerations of the nervous system of the bird

1899 ◽  
Vol 64 (402-411) ◽  
pp. 176-179 ◽  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Previous Literature ◽  
Modern Methods ◽  
The Central Nervous System ◽  
The Subject ◽  
The Brain

In this research the modern methods of investigating the course of tracts and their degeneration in the central nervous system have been used. The previous literature of the subject is scanty. Bumm first gave an account of the various tracts in the brain, and the histological side has been and is still being worked out by Brandis. Valuable information is given by Edinger in his ‘Vorlesungen,’ and quite recently the Marchi method has been used and the results obtained described by Wiener and Münzer, Wallenberg and Friedländer.

scholarly journals Brain-gut-microbiota axis in motor disorders

2021 ◽  
Author(s):  
Dariana Rodrigues Andrade ◽  
Letícia Mendes de Lima ◽  
Luis Henrique Goes Hamati Rosa ◽  
Edvaldo Cardoso
Keyword(s):  
Nervous System ◽  
Gut Microbiota ◽  
Intestinal Microbiota ◽  
Drug Targets ◽  
Fecal Microbiota Transplantation ◽  
Strong Relationship ◽  
Central Component ◽  
Motor Disorders ◽  
Vagus Nerves ◽  
The Brain

Introduction: There seems to be a strong relationship and influence on the brain-gut- microbiota axis in the control and prevention of several diseases, including degenerative diseases that are related to motor disorders. Objectives: To analyze the relationship between movement disorders and the intestinal microbiota. Methods: Integrative review performed at PUBMED, using the descriptors Movement disorder and intestinal microbiota, in the last five years and having as inclusion criteria complete texts in English. Results: The literature suggests that the intestinal microbiota regulates the activation of microglia through the production of bacteria metabolites. Gut dysbiosis is believed to generate metabolic disorders with decreased production of neuroprotective factors, increased pro-inflammatory cytokines, production of neurotoxins, and a misdirected immune response. Metabolites produced by an altered microbiota seem to enter the circulation and affect neurological function. Braak’s hypothesis postulates that aberrant accumulation of α-synuclein (αSyn), a central component of the pathophysiology of Parkinson’s disease (PD), begins in the intestine and propagates through the vagus nerve to the brain, given that αSyn inclusions previously arise in the enteric nervous system and glossopharyngeal and vagus nerves, and vagotomized individuals have reduced risk of PD. Conclusion: The identification of the microbiota or its altered metabolites may serve as biomarkers, or even drug targets for the treatment of diseases of the central nervous system. The microbiota can be modulated through antibiotic therapy, fecal microbiota transplantation, prebiotic supplementation, dietary interventions and many other potential methods.

Glucuronyl 3-sulfate occurs exclusively on distal unmyelinated terminals of selected sensory neurons in the peripheral nervous system

1995 ◽  
Vol 53 ◽  
pp. 958-959
Author(s):  
S.S. Spicer ◽  
B.A. Schulte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cerebral Cortex ◽  
Peripheral Nervous System ◽  
Sensory Neurons ◽  
Sensory Nerves ◽  
Tissue Antigens ◽  
The Central Nervous System ◽  
The Brain ◽  
Leu 7

Generation of monoclonal antibodies (MAbs) against tissue antigens has yielded several (VC1.1, HNK- 1, L2, 4F4 and anti-leu 7) which recognize the unique sugar epitope, glucuronyl 3-sulfate (Glc A3- SO4). In the central nervous system, these MAbs have demonstrated Glc A3-SO4 at the surface of neurons in the cerebral cortex, the cerebellum, the retina and other widespread regions of the brain.Here we describe the distribution of Glc A3-SO4 in the peripheral nervous system as determined by immunostaining with a MAb (VC 1.1) developed against antigen in the cat visual cortex. Outside the central nervous system, immunoreactivity was observed only in peripheral terminals of selected sensory nerves conducting transduction signals for touch, hearing, balance and taste. On the glassy membrane of the sinus hair in murine nasal skin, just deep to the ringwurt, VC 1.1 delineated an intensely stained, plaque-like area (Fig. 1). This previously unrecognized structure of the nasal vibrissae presumably serves as a tactile end organ and to our knowledge is not demonstrable by means other than its selective immunopositivity with VC1.1 and its appearance as a densely fibrillar area in H&E stained sections.

Ultrastructural morphology of neurosecretory neurons in the barnacle Balanus amphitrite

1990 ◽  
Vol 48 (3) ◽  
pp. 434-435
Author(s):  
Grazia Tagliafierro ◽  
Cristiana Crosa ◽  
Marco Canepa ◽  
Tiziano Zanin
Keyword(s):  
Nervous System ◽  
Ultrastructural Level ◽  
Uranyl Acetate ◽  
Balanus Amphitrite ◽  
Neurosecretory Neurons ◽  
The Central Nervous System ◽  
Ultrathin Sections ◽  
Dense Core Granules ◽  
The Brain ◽  
Ocellar Nerve

Barnacles are very specialized Crustacea, with strongly reduced head and abdomen. Their nervous system is rather simple: the brain or supra-oesophageal ganglion (SG) is a small bilobed structure and the toracic ganglia are fused into a single ventral mass, the suboesophageal ganglion (VG). Neurosecretion was shown in barnacle nervous system by histochemical methods and numerous putative hormonal substances were extracted and tested. Recently six different types of dense-core granules were visualized in the median ocellar nerve of Balanus hameri and serotonin and FMRF-amide like substances were immunocytochemically detected in the nervous system of Balanus amphitrite. The aim of the present work is to localize and characterize at ultrastructural level, neurosecretory neuron cell bodies in the VG of Balanus amphitrite.Specimens of Balanus amphitrite were collected in the port of Genova. The central nervous system were Karnovsky fixed, osmium postfixed, ethanol dehydrated and Durcupan ACM embedded. Ultrathin sections were stained with uranyl acetate and lead citrate. Ultrastructural observations were made on a Philips M 202 and Zeiss 109 T electron microscopy.

Complex Trauma and Prenatal Alcohol Exposure: Clinical Implications

2012 ◽  
Vol 13 (2) ◽  
pp. 32-42 ◽  
Author(s):  
Yvette D. Hyter
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Child Development ◽  
Academic Outcomes ◽  
Complex Trauma ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Clinical Implications ◽  
Prenatal Alcohol ◽  
The Brain

Abstract Complex trauma resulting from chronic maltreatment and prenatal alcohol exposure can significantly affect child development and academic outcomes. Children with histories of maltreatment and those with prenatal alcohol exposure exhibit remarkably similar central nervous system impairments. In this article, I will review the effects of each on the brain and discuss clinical implications for these populations of children.

Central Nerve System Impairment, AMA Guides, Sixth Edition: An Overview

2018 ◽  
Vol 23 (1) ◽  
pp. 10-13
Author(s):  
James B. Talmage ◽  
Jay Blaisdell
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Neurological Impairment ◽  
Sixth Edition ◽  
Central Nerve System ◽  
The Central Nervous System ◽  
The One ◽  
Nerve System ◽  
The Brain

Abstract Injuries that affect the central nervous system (CNS) can be catastrophic because they involve the brain or spinal cord, and determining the underlying clinical cause of impairment is essential in using the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), in part because the AMA Guides addresses neurological impairment in several chapters. Unlike the musculoskeletal chapters, Chapter 13, The Central and Peripheral Nervous System, does not use grades, grade modifiers, and a net adjustment formula; rather the chapter uses an approach that is similar to that in prior editions of the AMA Guides. The following steps can be used to perform a CNS rating: 1) evaluate all four major categories of cerebral impairment, and choose the one that is most severe; 2) rate the single most severe cerebral impairment of the four major categories; 3) rate all other impairments that are due to neurogenic problems; and 4) combine the rating of the single most severe category of cerebral impairment with the ratings of all other impairments. Because some neurological dysfunctions are rated elsewhere in the AMA Guides, Sixth Edition, the evaluator may consult Table 13-1 to verify the appropriate chapter to use.

Sign in / Sign up

Export Citation Format

Share Document