scholarly journals Synthesis and characterization of Fe3O4/PEG-400/oxalic acid magnetic nanoparticles as a heterogeneous catalyst for synthesis of pyrrolin-2-ones derivatives

2021 ◽  
pp. 59-59
Author(s):  
Seyran Esmaeilzadeh ◽  
Davood Setamdideh
Keyword(s):  
Oxalic Acid ◽  
Mass Spectra ◽  
Chemical Structure ◽  
Room Temperature ◽  
One Pot ◽  
Chemical Structures ◽  
Peg 400 ◽  
Ft Ir ◽  
New Compounds

In this study, oxalic acid has been successfully loaded on Fe3O4/PEG-400 under ultrasonic irradiation and Fe3O4/PEG/oxalic acid as a new nanomagnetic catalyst has been synthesized. The chemical structure of the catalyst has been investigated by FT-IR spectrum, XRD, EDX and SEM methods. The catalyst has been used for the synthesis of 3-acyl-5-hydroxy-3-pyrrolin-2-one derivatives from the corresponding aldehydes, anilines and dimethyl acetylenedicarboxylate (DMAD) by one-pot and three-component the MCR reaction in the excellent yields (90-95 %) of products within 24 hours at room temperature. The fourteen samples are available. The recovered catalyst could be satisfactorily used for the second and third run without regeneration. This method has green and eco-friendly profile. Also, this research introduces an improvement mechanism for the types of this reaction. The chemical structures of new compounds have been characterized by FT-IR, 1H-NMR, 13C-NMR, and Mass spectra.

New bioactive metabolites from Penicillium purpurogenum MM

2016 ◽  
Vol 71 (4) ◽  
pp. 287-295 ◽  
Author(s):  
Mohamed Shaaban ◽  
Mohammad Magdy El-Metwally ◽  
Hartmut Laatsch
Keyword(s):  
Mass Spectra ◽  
Dimethyl Acetal ◽  
Bioactive Metabolites ◽  
Cytotoxic Activities ◽  
Penicillium Purpurogenum ◽  
Chemical Structures ◽  
Ergosterol Peroxide ◽  
New Compounds ◽  
Taxonomic Characterization

AbstractThree new bioactive compounds, namely (S)-tenellic acid B dimethyl acetal (1a), (3R,3′R/S)-isotalarone (2), and (3R,5R)-cis-5-methyl-3-(2-oxobutyl)-dihydrofuran-2-one (3), were isolated from the terrestrial fungus Penicillium purpurogenum MM, together with 15 known metabolites: talaroflavone, pestalasin A, altenuene, penicillide, 3′-O-methyl-dehydroisopenicillide, rubralactone, tenellic acid B, diaporthin, butyrolactone 1, butyrolactone-V, 4-hydroxy-2-methoxyacetanilide, ergosterol, ergosterol peroxide, linoleic acid, and glycerol monolinoleate. The chemical structures of the three new compounds were confirmed by extensive one- and two-dimensional NMR and electron spray ionization high-resolution mass spectra measurements and by comparison with literature data. The absolute configurations of the new compounds, and of talaroflavone (4a) and tenellic acid B (2b), were determined by ab initio calculations of ECD, ORD, and NMR data. The antimicrobial and cytotoxic activities of the crude extract and of the isolated compounds were studied using a set of microorganisms and brine shrimp assay, respectively. The isolation and taxonomic characterization of P. purpurogenum MM is reported.

Preparation and Characterization of Soybean Oil-based Flame Retardant Rigid Polyurethane Foams Containing Phosphaphenanthrene Groups

2020 ◽  
Vol 17 (10) ◽  
pp. 760-771
Author(s):  
Qirui Gong ◽  
Niangui Wang ◽  
Kaibo Zhang ◽  
Shizhao Huang ◽  
Yuhan Wang
Keyword(s):  
Soybean Oil ◽  
Flame Retardant ◽  
Chemical Structure ◽  
Cell Structure ◽  
Polyurethane Foams ◽  
Limiting Oxygen Index ◽  
Rigid Polyurethane Foams ◽  
Degradation Activation Energy ◽  
Ft Ir

A phosphaphenanthrene groups containing soybean oil based polyol (DSBP) was synthesized by epoxidized soybean oil (ESO) and 9,10-dihydro-oxa-10-phosphaphenanthrene-10-oxide (DOPO). Soybean oil based polyol (HSBP) was synthesized by ESO and H2O. The chemical structure of DSBP and HSBP were characterized with FT-IR and 1H NMR. The corresponding rigid polyurethane foams (RPUFs) were prepared by mixing DSBP with HSBP. The results revealed apparent density and compression strength of RPUFs decreased with increasing the DSBP content. The cell structure of RPUFs was examined by scanning electron microscope (SEM) which displayed the cells as spherical or polyhedral. The thermal degradation and flame retardancy of RPUFs were investigated by thermogravimetric analysis, limiting oxygen index (LOI), and UL 94 vertical burning test. The degradation activation energy (Ea) of first degradation stage reduced from 80.05 kJ/mol to 37.84 kJ/mol with 80 wt% DSBP. The RUPF with 80 wt% DSBP achieved UL94 V-0 rating and LOI 28.3. The results showed that the flame retardant effect was mainly in both gas phase and condensed phase.

scholarly journals Clean one-pot multicomponent synthesis of pyrans using a green and magnetically recyclable heterogeneous nanocatalyst

SynOpen ◽  
2021 ◽  
Author(s):  
Mina Ghassemi ◽  
Ali Maleki
Keyword(s):  
Room Temperature ◽  
Significant Loss ◽  
Copper Ferrite ◽  
Multicomponent Synthesis ◽  
Thermo Gravimetric ◽  
Sem Images ◽  
One Pot ◽  
Three Component Reaction ◽  
Ft Ir ◽  
The One

Copper ferrite (CuFe2O4) magnetic nanoparticles (MNPs) were synthesized via thermal decomposition method and applied as a reusable and green catalyst in the synthesis of functionalized 4H-pyran derivatives using malononitrile, an aromatic aldehyde and a β-ketoester in ethanol at room temperature. Then it was characterized by Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX) analysis, scanning electron microscopy (SEM) images, thermo gravimetric and differential thermo gravimetric (TGA/DTG) analysis. The catalyst was recovered from the reaction mixture by applying an external magnet and decanting the mixture. Recycled catalyst was reused for several times without significant loss in its activity. Running the one-pot three-component reaction at room temperature, no use of eternal energy source and using a green solvent provide benign, mild, and environmentally friendly reaction conditions; as well, ease of catalyst recovering, catalyst recyclability, no use of column chromatography and good to excellent yields are extra advantages of this work.

scholarly journals 5-((8-Hydroxyquinolin-5-yl)diazenyl)-3-methyl-1H-pyrazole-4-carboxylic Acid

Molbank ◽  
10.3390/m1238 ◽  
2021 ◽  
Vol 2021 (2) ◽  
pp. M1238
Author(s):  
Ion Burcă ◽  
Valentin Badea ◽  
Calin Deleanu ◽  
Vasile-Nicolae Bercean
Keyword(s):  
Chemical Structure ◽  
Functional Group ◽  
Coupling Reaction ◽  
2D Nmr ◽  
Azo Coupling ◽  
2D Nmr Spectroscopy ◽  
Azo Compound ◽  
Ft Ir ◽  
New Compounds ◽  
Carboxylic Functional Group

A new azo compound was prepared via the azo coupling reaction between 4-(ethoxycarbonyl)-3-methyl-1H-pyrazole-5-diazonium chloride and 8-hydroxyquinoline (oxine). The ester functional group of the obtained compound was hydrolyzed and thus a new chemical structure with a carboxylic functional group resulted. The structures of the new compounds were fully characterized by: UV–Vis, FT-IR, 1D and 2D NMR spectroscopy, and HRMS spectrometry.

scholarly journals Synthesis and Bioinformatic Characterization of New Schiff Bases with Possible Applicability in Brain Disorders

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4160
Author(s):  
Speranta Avram ◽  
Ana Maria Udrea ◽  
Diana Camelia Nuta ◽  
Carmen Limban ◽  
Adrian Cosmin Balea ◽  
...  
Keyword(s):  
Schiff Bases ◽  
Neurodegenerative Disorders ◽  
Aromatic Aldehydes ◽  
Brain Disorders ◽  
Ir And Nmr Spectroscopy ◽  
Bioinformatics Tools ◽  
Ft Ir ◽  
New Treatments ◽  
New Compounds

(1) Background: The research aims to find new treatments for neurodegenerative diseases, in particular, Alzheimer’s disease. (2) Methods: This article presents a bioinformatics and pathology study of new Schiff bases, (EZ)-N′-benzylidene-(2RS)-2-(6-chloro-9H-carbazol-2-yl)propanehydrazide derivatives, and aims to evaluate the drug-like, pharmacokinetic, pharmacodynamic and pharmacogenomic properties, as well as to predict the binding to therapeutic targets by applying bioinformatics, cheminformatics and computational pharmacological methods. (3) Results: We obtained these Schiff bases by condensing (2RS)-2-(6-chloro-9H-carbazol-2-yl)propanehydrazide with aromatic aldehydes, using the advantages of microwave irradiation. The newly synthesized compounds were characterized spectrally, using FT-IR and NMR spectroscopy, which confirmed their structure. Using bioinformatics tools, we noticed that all new compounds are drug-likeness features and may be proposed as potentially neuropsychiatric drugs (4) Conclusions: Using bioinformatics tools, we determined that the new compound 1e had a high potential to be used as a good candidate in neurodegenerative disorders treatment.

New soluble 4-(4-formyl-2,6-dimethoxyphenoxy) substituted phthalocyanines: Synthesis, characterization, photophysical and photochemical properties

2021 ◽  
pp. 1-10
Author(s):  
Ibrahim Erden ◽  
Betül Karadoğan ◽  
Fatma Aytan Kılıçarslan ◽  
Göknur Yaşa Atmaca ◽  
Ali Erdoğmuş
Keyword(s):  
Quantum Yield ◽  
Singlet Oxygen ◽  
Fluorescence Quantum Yield ◽  
Metal Ion ◽  
Mass Spectra ◽  
Quantum Yields ◽  
Therapeutic Outcomes ◽  
Ft Ir ◽  
Photochemical Properties ◽  
New Compounds

This work describes the synthesis, spectral and fluorescence properties of bis 4-(4-formyl-2,6-dimethoxyphenoxy) substituted zinc (ZnPc) and magnesium (MgPc) phthalocyanines. The new compounds have been characterized by elemental analysis, UV-Vis, FT-IR, 1H-NMR and mass spectra. Afterward, the effects of including metal ion on the photophysicochemical properties of the complexes were studied in biocompatible solvent DMSO to analyze their potential to use as a photosensitizer in photodynamic therapy (PDT). The fluorescence and singlet oxygen quantum yields were calculated as 0.04–0.15 and 0.70–0.52 for ZnPc and MgPc, respectively. According to the results, MgPc has higher fluorescence quantum yield than ZnPc, while ZnPc has higher singlet oxygen quantum yield than MgPc. The results show that the synthesized complexes can have therapeutic outcomes for cancer treatment.

scholarly journals Synthesis and Characterization of 2-Pyrazoline Derivatives and their in silico and in vitro Studies on Antimicrobial and Anticancer Activities

2019 ◽  
Vol 31 (10) ◽  
pp. 2191-2196 ◽  
Author(s):  
S. Rathinamanivannan ◽  
K. Megha ◽  
Raja Chinnamanayakar ◽  
Ashok Kumar ◽  
M.R. Ezhilarasi
Keyword(s):  
Breast Cancer ◽  
Synthesis And Characterization ◽  
Anticancer Activities ◽  
1H And 13C Nmr ◽  
Chemical Structures ◽  
Ft Ir ◽  
Affinity Score ◽  
High Binding Affinity

The new series of 1-(4,5-dihydro-5-phenyl-3-diphenylpyrazol-1-yl)butan-1-one derivatives were synthesized by cyclization method using biphenyl chalcone with n-butyric acid and hydrazine hydrate. The synthesized 1-(4,5-dihydro-5-phenyl-3-diphenylpyrazol-1-yl)butan-1-one derivatives chemical structures were confirmed from spectral data such as FT-IR, 1H and 13C NMR. 2-Pyrazoline derivatives were docked with bacterial (1UAG) and breast cancer (1OQA) protein. Based on high binding affinity score, the best compound was subjected to in vitro anticancer activity by MTT assay. Also, antimicrobial activity were studied for synthesized 2-pyrazoline derivatives.

scholarly journals Chemical Structure of Mangrove Species Rhizophora stylosa as Natural Dyes

METANA ◽  
2020 ◽  
Vol 16 (1) ◽  
pp. 33-38
Author(s):  
Paryanto Paryanto ◽  
Sunu Herwi Pranolo ◽  
Ari Diana Susanti ◽  
Kristina Ratna Dewi ◽  
Meydiana Rossari
Keyword(s):  
Chemical Structure ◽  
Liquid Extraction ◽  
Natural Dyes ◽  
Synthetic Dyes ◽  
Mangrove Species ◽  
Rhizophora Stylosa ◽  
Solid Mixture ◽  
Chemical Structures ◽  
Ft Ir ◽  
Solid Liquid

Textile dyes are divided into two types, natural dyes and synthetic dyes. Natural dyes commonly made from extraction. Extraction is a process in which one or more components are separated selectively from a liquid or solid mixture, the feed, by means of a liquid immiscible solvent. Extraction can be classified into two group, liquid extraction and solid-liquid extraction. Solvents that are usually used in the extraction of natural dyes are aquades and ethanol. The purpose of this research was to determine the chemical structure, especially tannin in natural dyes from mangrove species Rhizophora stylosa through several samples testing natural dyes. Rhizophora stylosa that have been extracted and evaporated will conducted several tests to obtain chemical structures in natural dyes and yield of tannin in natural dyes. Tests carried out include testing FT-IR, and HPLC. Based on FT-IR analysis, the extraction of Rhizophora stylosa containing tannin indicated by the presence of hydroxyl (O-H) in the area of 3385.36 cm-1, aromatic (C-H) in the area of 1365.53 cm-1, carbonyl (C=O) in the area 1646.36 cm-1, esters (C-O) in the area 1217.30 cm-1. While tannin content obtained from the analysis of HPLC were 6.087 ppm. 

scholarly journals Efficient Synthesis and Characterization of Some Novel Nitro-Schiff Bases and Their Complexes of Nickel(II) and Copper(II)

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Hossein Naeimi ◽  
Mohsen Moradian
Keyword(s):  
Schiff Base ◽  
Schiff Base Complexes ◽  
Synthesis And Characterization ◽  
Planar Geometry ◽  
Hydroxyl Groups ◽  
Spectroscopic Techniques ◽  
Spectral Techniques ◽  
Chemical Structures ◽  
Ft Ir

Synthesis and characterization of some new Schiff base ligands derived from various diamines and nitrosalicylaldehyde and their complexes of Ni(II) and Cu(II) are reported. Several spectral techniques such as UV-Vis, FT-IR, and NMR spectra were used to identify the chemical structures of the reported ligands and their complexes. The ligands are found to be bound to the metal atom through the oxygen atoms of the hydroxyl groups and nitrogen atoms of imine groups, which is also supported by spectroscopic techniques. The results obtained by FT-IR and NMR showed that the Schiff base complexes of transition metal (II) have square-planar geometry.

scholarly journals Thermal characterization of novel aliphatic polyesters with ether and thioether linkages

e-Polymers ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
M. Soccio ◽  
N. Lotti ◽  
L. Finelli ◽  
A. Munari
Keyword(s):  
Thermal Stability ◽  
Molecular Weight ◽  
Chemical Structure ◽  
Room Temperature ◽  
Crystallization Rate ◽  
Thermal Characterization ◽  
Scanning Calorimetry ◽  
Aliphatic Polyesters ◽  
Good Thermal Stability

AbstractSeveral novel ether or thioether linkage containing aliphatic polyesters and poly(alkylene dicarboxylate)s were synthesized for comparison and characterized in terms of chemical structure and molecular weight. The thermal behavior was examined by thermogravimetric analysis and differential scanning calorimetry. All the polymers showed a good thermal stability, even though lower for the ether or thioether linkage-containing polyesters. The decrement of the thermal stability appears to be more relevant in the case of the presence of sulphur atoms. At room temperature the samples appeared semicrystalline, except PTTDG and PDEDG, which were viscous oils; the effect of the introduction of ether or thioether group was an increment of the Tgvalue, a decrement of the melting temperature and a significant decrease of the crystallization rate. The entity of the variations was found to be affected by the kind of group introduced, and the trend observed can be explained on the basis of atom electronegativity and dimensions

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