scholarly journals Influence of different types of surgical suture material on the intensity of tissue reaction in oral cavity

2008 ◽  
pp. 91-99
Author(s):  
Sinisa Mirkovic ◽  
Ljubisa Dzambas ◽  
Srecko Selakovic
Keyword(s):  
Suture Material ◽  
Oral Surgery ◽  
Fibrous Tissue ◽  
Tissue Reaction ◽  
Routine Practice ◽  
Suture Materials ◽  
Experimental Conditions ◽  
Monofilament Suture ◽  
Surgical Suture ◽  
Basic Features

Throughout the history the most diverse suture material have been used for closing and suturing surgical wounds. The four basic features of suture material are described: knot safety, stretch capacity, tissue reactivity and wound safety. Tissue reaction, even the minimum one, which develops during the first to seven days after applying the suture in the tissue. The aim of this study was to investigate influence of a monofilament suture material (nylon) on the intensity of local tissue reaction in experimental conditions, and to compare it with the multifilament suture used in the routine practice of oral surgery (silk). This investigation is a prospective experimental study carried out on Wistar rats. The experiment included 30 animals, in which Black Silk (thickness 4-1) and Nylon (thickness 4-0) were applied in the upper and lower jaw, respectively. To monitor tissue reaction on different suture materials the following parameters were used: coagulum formation, presence of polymorphonuclear leukocytes, presence of macrophages and granuloma, formation of epithelial bridge and connective tissue, collagen synthesis, granulomatous tissue formation and presence of fibrous tissue. After comparing parameters for the intensity of tissue reaction to the investigate suture materials by suturing the oral mucosa, certain advantage could be given to the monofilament suture materials.

scholarly journals Comparative study of tissue response to polyglecaprone 25, polyglactin 910 and polytetrafluorethylene suture materials in rats

2002 ◽  
Vol 13 (2) ◽  
pp. 86-91 ◽  
Author(s):  
Hugo Nary Filho ◽  
Mariza Akemi Matsumoto ◽  
Aline Carvalho Batista ◽  
Luís César Lopes ◽  
Fernanda Costa Grizzo de Sampaio Góes ◽  
...  
Keyword(s):  
Suture Material ◽  
Oral Surgery ◽  
Subcutaneous Tissue ◽  
Tissue Response ◽  
Biological Behavior ◽  
Dorsal Region ◽  
Suture Materials ◽  
Polyglactin 910 ◽  
Hematoxylin And Eosin ◽  
Selection Of

The authors evaluated the biocompatibility of three suture materials, polyglecaprone 25, polyglactin 910 and polytetrafluorethylene, implanted into subcutaneous tissue in the dorsal region of 20 Wistar albinus rats. After periods of 2, 7, 14 and 21 days, the rats were sacrificed and the specimens were processed for routine histotechnical analysis and stained with hematoxylin and eosin. The rate of fibrosis, angioblastic and fibroblastic proliferation, and also the intensity of inflammation were observed with the optic microscope. The results showed that polyglecaprone 25 suture material induced a mild inflammatory reaction, followed by polyglactin 910 and polytetrafluorethylene, respectively. Such biological behavior must be considered during the selection of the suture material to be used in oral surgery.

scholarly journals Influence of different types of surgical suture materials on mehanical damage of oral mucosa

2011 ◽  
Vol 64 (3-4) ◽  
pp. 157-160 ◽  
Author(s):  
Sinisa Mirkovic ◽  
Tatjana Djurdjevic-Mirkovic
Keyword(s):  
Oral Mucosa ◽  
Soft Tissues ◽  
Tissue Reaction ◽  
Control Group ◽  
Prospective Clinical Study ◽  
Suture Materials ◽  
Surgical Suture ◽  
Surgical Wounds ◽  
Synthetic Monofilament ◽  
Basic Characteristics

Introduction. Throughout history many kinds of different suture materials have been used for closing and suturing surgical wounds. Medical literature describes four basic characteristics of suture material: knot safety, tensile strength, tissue reaction and wound safety. The tissue reaction is reflected in an inflammatory response, which, though minimal, occurs during first two to seven days after implanting suture into the tissue. The aim of this research was to investigate whether different suture materials affect the development of decubital damage of oral mucosa, which to a great extent can compromise the process of wound healing. Material and methods. The investigation was designed as a prospective clinical study including 150 patients of both genders, aged between 25 and 60. The patients were distributed into three groups of 50 persons. The suture Black Silk was used in the first group, designated as a control group. Nylon and Vicril were used in the second and third group, i.e. experimental groups, respectively. Decubital damage of the surrounding soft tissues was the main parameter for monitoring the effects of selected suture materials on the oral mucosa. Conclusion. The comparison of results obtained for the investigated suture materials after suturing oral mucosa revealed that certain advan?tage could be given to synthetic monofilament suture materials

scholarly journals Clinical and histologic tissue responses of skin incisions closed with glycomer 631 and lactomer 9-1 using subcuticular technique in pigs

2019 ◽  
Author(s):  
Tanja Plavec ◽  
Tanja Švara ◽  
Irena Zdovc ◽  
Mitja Gombač ◽  
Marija Damjanovska ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Suture Material ◽  
Giant Cells ◽  
Tissue Reaction ◽  
Absorbable Suture ◽  
Suture Materials ◽  
Tissue Samples ◽  
Trueperella Pyogenes ◽  
Cumulative Score ◽  
Tissue Reactions

Abstract Background: Glycomer 631 and lactomer 9-1 are absorbable suture materials indicated for soft tissue approximation in non-infected wounds. Pigs are often used as surgical models in translational research, however, the reports of tissue reactions to both suture materials in pigs are lacking. The aim of this study was to assess clinical and histologic responses of skin incisions closed with subcuticular technique using glycomer 631 and lactomer 9-1 in pigs. Results: Skin incisions of 17 pigs were closed with glycomer 631 and lactomer 9-1 and clinical reactive score (CRS) including erythema, swelling, discharge, and dehiscence was calculated on postoperative days 7 and 14. Subcuticular tissue reaction was assessed histologically on postoperative day 14 (the presence of extravascular neutrophils, macrophages, multinucleated giant cells, lymphocytes, fibroblasts, bacterial colonies, overall severity of inflammatory response to suture material), and the cumulative score of variables calculated as aggregate tissue irritation score (ATIS). Tissue samples were examined for suture extrusion and evaluated microbiologically. Clinical reactive score did not differ between the suture materials. Only one variable of ATIS, overall severity of inflammatory response, was lower ( p = 0.029) when glycomer 631 was used. Suture extrusion was found in 10/17 of incisions closed by glycomer 631 and in 7/13 of incisions closed by lactomer 9-1. Trueperella pyogenes was isolated from the skin and from the area of tissue reaction in six pigs. Conclusions: No difference in CRS between the suture materials was observed. Glycomer 631 induced less tissue reaction only in terms of overall severity of inflammatory response. Suture extrusion was observed in more than 50% of incisions regardless of the suture material. Trueperella pyogenes was the only pathogen isolated from the tissue surrounding the suture material.

A prospective randomized trial of suture material in aural wound closure

1988 ◽  
Vol 102 (9) ◽  
pp. 788-790 ◽  
Author(s):  
D. J. Willatt ◽  
L. Durham ◽  
M. F. Ramadan ◽  
N. Bark-Jones
Keyword(s):  
Wound Healing ◽  
Wound Closure ◽  
Suture Material ◽  
Wound Dehiscence ◽  
Chromic Catgut ◽  
Wound Infections ◽  
Suture Materials ◽  
Factors Affecting ◽  
Monofilament Suture ◽  
Synthetic Monofilament

AbstractThe aim of the study was to compare synthetic monofilament suture materials with chromic catgut and silk in aural wound closure. Forty patients undergoing mastoidectomy or tympanoplasty were randomized to closure with either 30 PDS (Polydioxanone) to fascia plus 30 Prolene to skin, or 20 chromic catgut to fascia plus 30 silk to skin. Known or suspected factors affecting wound healing were recorded. Nine patients had post-operative wound infections. The infection rate was significantly lower in wounds closed with PDS and Prolene (χ2 = 6.05, p<.05), and in tympanoplasty operations (χ2 = 4.42, p<.05). Four patients suffered wound dehiscence, all four had been closed with catgut and silk. No other complication of wound healing was noted in the trial. In conclusion, PDS and Prolene are superior suture materials to catgut and silk in the closure of aural wounds.

scholarly journals Clinical and histologic tissue responses of skin incisions closed with glycomer 631 and lactomer 9-1 using subcuticular technique in pigs

2019 ◽  
Author(s):  
Tanja Plavec ◽  
Tanja Švara ◽  
Irena Zdovc ◽  
Mitja Gombač ◽  
Marija Damjanovska ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Suture Material ◽  
Giant Cells ◽  
Tissue Reaction ◽  
Absorbable Suture ◽  
Suture Materials ◽  
Tissue Samples ◽  
Trueperella Pyogenes ◽  
Cumulative Score ◽  
Tissue Reactions

Abstract Background: Glycomer 631 and lactomer 9-1 are absorbable suture materials indicated for soft tissue approximation in non-infected wounds. Pigs are often used as surgical models in translational research, however, the reports of tissue reactions to both suture materials in pigs are limited. The aim of this study was to assess clinical and histologic responses of skin incisions closed with subcuticular technique using glycomer 631 and lactomer 9-1 in pigs. Results: Skin incisions of 17 pigs were closed with glycomer 631 and lactomer 9-1 and clinical reactive score (CRS) including erythema, swelling, discharge, and dehiscence was calculated on postoperative days 7 and 14. Subcuticular tissue reaction was assessed histologically on postoperative day 14 (the presence of extravascular neutrophils, macrophages, multinucleated giant cells, lymphocytes, fibroblasts, bacterial colonies, overall severity of inflammatory response to suture material), and the cumulative score of variables calculated as aggregate tissue irritation score (ATIS). Tissue samples were examined for suture extrusion and evaluated microbiologically. Clinical reactive score did not differ between the suture materials. Only one variable of ATIS, overall severity of inflammatory response, was lower (p = 0.029) when glycomer 631 was used. Suture extrusion was found in 10/17 of incisions closed by glycomer 631 and in 7/13 of incisions closed by lactomer 9-1. Trueperella pyogenes was isolated from the skin and from the area of tissue reaction in six pigs. Conclusions: No difference in CRS between the suture materials was observed. Glycomer 631 induced less tissue reaction only in terms of overall severity of inflammatory response. Suture extrusion was observed in more than 50% of incisions regardless of the suture material. Trueperella pyogenes was the only pathogen isolated from the tissue surrounding the suture material. Thinner suture material with less knots should be used for subcuticular closure in pigs.

scholarly journals Clinical and histologic tissue responses of skin incisions closed with glycomer 631 and lactomer 9-1 using a subcuticular technique in pigs

2020 ◽  
Author(s):  
Tanja Plavec ◽  
Tanja Švara ◽  
Irena Zdovc ◽  
Mitja Gombač ◽  
Marija Damjanovska ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Suture Material ◽  
Giant Cells ◽  
Tissue Reaction ◽  
Absorbable Suture ◽  
Suture Materials ◽  
Tissue Samples ◽  
Trueperella Pyogenes ◽  
Cumulative Score ◽  
Tissue Reactions

Abstract Background : Glycomer 631 and lactomer 9-1 are absorbable suture materials indicated for soft tissue approximation in non-infected wounds. Pigs are often used as surgical models in translational research; however, reports of tissue reactions to both suture materials in pigs are limited. The aim of this study was to assess clinical and histologic responses of skin incisions closed with a subcuticular technique using glycomer 631 and lactomer 9-1 in pigs. Results: Skin incisions on 17 pigs were closed with glycomer 631 and lactomer 9-1, and a clinical reactive score (CRS) including erythema, swelling, discharge and dehiscence was calculated on postoperative days 7 and 14. Subcuticular tissue reaction was assessed histologically on postoperative day 14 (the presence of extravascular neutrophils, macrophages, multinucleated giant cells, lymphocytes, fibroblasts, bacterial colonies and the overall severity of the inflammatory response to the suture material), and the cumulative score of the variables was calculated as an aggregate tissue irritation score (ATIS). Tissue samples were examined for suture extrusion and evaluated microbiologically. The clinical reactive score did not differ between the suture materials. Only one ATIS variable, namely the overall severity of the inflammatory response, was lower ( p = 0.029) when glycomer 631 was used. Suture extrusion was found in 10/17 of the incisions closed by glycomer 631 and in 7/13 of the incisions closed by lactomer 9-1. Trueperella pyogenes was isolated from the skin and from the area of tissue reaction in six pigs. Conclusions: No difference in CRS between the suture materials was observed, and thus both materials may be used for the subcuticular technique in pigs. Glycomer 631 induced less tissue reaction only in terms of the overall severity of the inflammatory response. Suture extrusion was observed in more than 50% of incisions regardless of the suture material, possibly due to a large amount of suture material in the wound. Trueperella pyogenes was the only pathogen isolated from the tissue surrounding the suture material.

scholarly journals Histological evaluation of five suture materials in the telson ligament of the American horseshoe crab (Limulus polyphemus)

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7061
Author(s):  
Ami E. Krasner ◽  
Amy Hancock-Ronemus ◽  
Larry S. Christian ◽  
Emily H. Griffith ◽  
Gregory A. Lewbart ◽  
...  
Keyword(s):  
Horseshoe Crab ◽  
Suture Material ◽  
Secondary Infection ◽  
Polyglycolic Acid ◽  
Tissue Reaction ◽  
Limulus Polyphemus ◽  
Histological Evaluation ◽  
Suture Materials ◽  
Soft Membrane ◽  
Horseshoe Crabs

An ideal suture material supports healing, minimizes inflammation, and decreases the likelihood of secondary infection. While there are published recommendations for suture materials in some invertebrates, there are no published recommendations for Limulus polyphemus or any chelicerate. This study evaluates the histological reaction of horseshoe crabs to five commonly used suture materials: monofilament nylon, silk, poliglecaprone, polydioxanone, and polyglycolic acid. None of the materials were superior with regards to holding nor was there any dehiscence. Nylon evoked the least amount of tissue reaction. This work also provides a histopathological description of the soft membrane at the hinge area between the opisthosoma and telson (telson ligament) and comments on euthanasia with intracardiac eugenol.

Suture Materials and Technics, Possible Cause for C-Section Scar Defect

2017 ◽  
Vol 752 ◽  
pp. 54-58 ◽  
Author(s):  
Aida Petca ◽  
Dan Cristian Radu ◽  
Mona Zvâncă ◽  
Bogdan Mastalier-Manolescu ◽  
Răzvan Petca ◽  
...  
Keyword(s):  
Caesarean Section ◽  
Suture Material ◽  
Anterior Wall ◽  
Tissue Reaction ◽  
Suture Materials ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Materials Used ◽  
Possible Cause

With the increasing number of births by Caesarean section a new pathology has made its presence felt, linked to the scarring of the low uterine transverse incision. It was found that after the birth by caesarean section some patients presented postmenstrual prolonged bleeding, spotting, pelvic pain and infertility. First described in 1995, the isthmocele is a healing defect in the anterior wall of the lower uterine segment at the caesarean hysterotomy site. This faulty scarring could be attributed to physiological peculiarities of the patient, to the suturing technique or ascribed to tissue reaction specifically to the type of suture material used. We found that it may be a correlation between the suture materials used and the appearance of the isthmocele. There are no large studies that asses the long-term outcome of C-section scar on prolonged menstrual bleeding, spotting and infertility and no comparison on the rate of appearance of this pathology by account of the suture material.

scholarly journals Choice of surgical suture material used in oral cavity: Clinical study

2010 ◽  
Vol 63 (7-8) ◽  
pp. 497-501 ◽  
Author(s):  
Sinisa Mirkovic ◽  
Tatjana Djurdjevic-Mirkovic ◽  
Branislav Bajkin ◽  
Ivan Sarcev
Keyword(s):  
Clinical Study ◽  
Oral Cavity ◽  
Soft Tissues ◽  
Suture Material ◽  
Wound Dehiscence ◽  
Prospective Clinical Study ◽  
Suture Materials ◽  
Surgical Suture ◽  
Wide Range ◽  
Operative Wound

Introduction. Historical data on closing and suturing of surgical wounds describe a wide range of various suture materials. The choice of the surgical catgut, i.e. type and diameter, depends on the localization, characteristics and condition of the tissue to be treated. From the stand-point of oral-surgical practice the following clinical parameters are of the outstanding importance regarding the choice of suture material: accumulation of soft deposits on the sutures, decubitus of the adjacent soft tissues and dehiscence of the operative wound. Aim. The aim of this research was to determine the correlation between different types of suture materials and accumulation of soft deposits on the sutures, decubitus of the adjacent soft tissues and dehiscence of the operative wound. Material and methods. Our prospective clinical study included 150 patients distributed into three groups of 50 subjects. The surgical procedure performed on each patient involved resection (apicoectomy) of the tooth root end in the intercanine sector of the upper jaw. The following suture materials were applied: BLACK SILK 5-0, NYLON 5-0 and VICRYL 5-0. The effects of the selected sutures were evaluated by using several parameters: accumulation of soft deposits, wound dehiscence and decubitus of the adjacent soft tissues. The effects of the applied sutures were recorded on days 2, 5 and 7 after the surgery. Conclusion. The comparison of cited parameters of the investigated materials after suture of oral cavity mucosa revealed that none of the used material was ideal; however, a certain preference might be given to the synthetic monofilament suture materials.

scholarly journals Clinical and histologic tissue responses of skin incisions closed with glycomer 631 and lactomer 9-1 using subcutaneous and subcuticular techniques in pigs

2019 ◽  
Author(s):  
Tanja Plavec ◽  
Tanja Švara ◽  
Irena Zdovc ◽  
Mitja Gombač ◽  
Marija Damjanovska ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Suture Material ◽  
Giant Cells ◽  
Tissue Reaction ◽  
Absorbable Suture ◽  
Suture Materials ◽  
Tissue Samples ◽  
Trueperella Pyogenes ◽  
Cumulative Score ◽  
Tissue Reactions

Abstract Background: Glycomer 631 and lactomer 9-1 are absorbable suture materials indicated for soft tissue approximation in non-infected wounds. Pigs are often used as surgical models in translational research, however, the reports of tissue reactions to both suture materials in pigs are deficient. The aim of this study was to assess clinical and histologic responses of skin incisions closed with subcutaneous and subcuticular techniques using glycomer 631 and lactomer 9-1 in pigs. Results: Skin incisions of 17 pigs were closed with glycomer 631 and lactomer 9-1 and clinical reactive score (CRS) including erythema, swelling, discharge, and dehiscence was calculated on postoperative days 7 and 14. Tissue reaction was assessed histologically on postoperative day 14 (the presence of extravascular neutrophils, macrophages, multinucleated giant cells, lymphocytes, fibroblasts, bacterial colonies, overall severity of inflammatory response to suture material), and the cumulative score of variables calculated as aggregate tissue irritation score (ATIS). Tissue samples were examined for suture extrusion and evaluated microbiologically. Clinical reactive score did not differ between the suture materials. Only one variable of ATIS, overall severity of inflammatory response, was lower (p = 0.029) when glycomer 631 was used. Suture extrusion was found in 10/17 of incisions closed by glycomer 631 and in 7/13 of incisions closed by lactomer 9-1. Trueperella pyogenes was isolated from the skin and from the area of tissue reaction in six pigs. Conclusions: No difference in CRS between the suture materials was observed. Glycomer 631 induced less tissue reaction only in terms of overall severity of inflammatory response. Suture extrusion was observed in more than 50% of incisions regardless of the suture material. Trueperella pyogenes was the only pathogen isolated from the tissue surrounding the suture material.

Sign in / Sign up

Export Citation Format

Share Document