scholarly journals Comparative study of tissue response to polyglecaprone 25, polyglactin 910 and polytetrafluorethylene suture materials in rats

2002 ◽  
Vol 13 (2) ◽  
pp. 86-91 ◽  
Author(s):  
Hugo Nary Filho ◽  
Mariza Akemi Matsumoto ◽  
Aline Carvalho Batista ◽  
Luís César Lopes ◽  
Fernanda Costa Grizzo de Sampaio Góes ◽  
...  
Keyword(s):  
Suture Material ◽  
Oral Surgery ◽  
Subcutaneous Tissue ◽  
Tissue Response ◽  
Biological Behavior ◽  
Dorsal Region ◽  
Suture Materials ◽  
Polyglactin 910 ◽  
Hematoxylin And Eosin ◽  
Selection Of

The authors evaluated the biocompatibility of three suture materials, polyglecaprone 25, polyglactin 910 and polytetrafluorethylene, implanted into subcutaneous tissue in the dorsal region of 20 Wistar albinus rats. After periods of 2, 7, 14 and 21 days, the rats were sacrificed and the specimens were processed for routine histotechnical analysis and stained with hematoxylin and eosin. The rate of fibrosis, angioblastic and fibroblastic proliferation, and also the intensity of inflammation were observed with the optic microscope. The results showed that polyglecaprone 25 suture material induced a mild inflammatory reaction, followed by polyglactin 910 and polytetrafluorethylene, respectively. Such biological behavior must be considered during the selection of the suture material to be used in oral surgery.

scholarly journals The Dynamics of Subcutaneous Tissue Response to Microorganisms Associated with the Extract of Araçá (Psidium cattleianum): An Edemogenic and Microscopic Analysis

2017 ◽  
Vol 20 (2) ◽  
pp. 93 ◽  
Author(s):  
Alessandra Cury Machado ◽  
Denise Belucio Ruviere ◽  
Renata Zoccal Novais ◽  
Carlos Roberto Emerenciano Bueno ◽  
Elerson Gaetti Jardim Jr ◽  
...  
Keyword(s):  
Subcutaneous Tissue ◽  
Tissue Response ◽  
Male Rats ◽  
Saline Control ◽  
Control Group ◽  
Dorsal Region ◽  
Hydroalcoholic Extract ◽  
Psidium Cattleianum ◽  
Significant Difference

<p><strong>Objective:</strong> To evaluate <em>in vivo </em>tissue reaction to the extract of araçá (<em>Psidium cattleianum</em>) associated with inactivated microorganisms. <strong>Material and Methods:</strong> A 0.1 mL suspension was used containing Porphyromonas gingivalis, Prevotella intermedia, <em>Fusobacterium nucleatum, Enterococcus faecalis, Peptostreptococcus micros</em>, and <em>Porphyromonas endodontalis,</em> which were inactivated by heat and mixed into a 1.0 mL saline (control group), an aqueous solution, or a hydroalcoholic extract of araçá. Eighteen male rats (<em>Rattus norvegiccus</em>) under general anesthesia received 0.2 mL of 1% intravenous Evans blue. Thirty minutes later, 0.1 mL of one of the associations was injected into the animals’ dorsal region. The animals were euthanized after 3 and 6 hours, and the materials obtained were placed in formamide for 72 hours then analyzed in a spectrophotometer (λ=630 hm). For the morphological analysis, 30 rats received polyethylene tubes implants with the extracts or the saline with the associations in the dorsal region and euthanized after 7 and 30 days to be analyzed according to an inflammation cell score. <strong>Results:</strong> No significant difference (p&gt;0.05) was observed in the edema among groups. The optical microscopy results showed a repair in the 30-day-period, which was higher when compared to the 7-day-period (p&lt;0.0001). Nevertheless, in the 7-day-period, the hydroalcoholic extract presented a significant response compared to the aqueous extract (p=0.05) and a trend for better results than the control group. <strong>Conclusion: </strong>The aqueous and hydroalcoholic araçá extracts associated with inactivated microorganisms showed similar responses to control, indicating no interference on the toxic effects of the bacterial components in tissue repair.</p><p><strong>Keywords</strong></p><p>Anaerobic bacteria; Edema; Inflammation; Plant extracts; <em>Psidium.</em></p>

scholarly journals Influence of different types of surgical suture material on the intensity of tissue reaction in oral cavity

2008 ◽  
pp. 91-99
Author(s):  
Sinisa Mirkovic ◽  
Ljubisa Dzambas ◽  
Srecko Selakovic
Keyword(s):  
Suture Material ◽  
Oral Surgery ◽  
Fibrous Tissue ◽  
Tissue Reaction ◽  
Routine Practice ◽  
Suture Materials ◽  
Experimental Conditions ◽  
Monofilament Suture ◽  
Surgical Suture ◽  
Basic Features

Throughout the history the most diverse suture material have been used for closing and suturing surgical wounds. The four basic features of suture material are described: knot safety, stretch capacity, tissue reactivity and wound safety. Tissue reaction, even the minimum one, which develops during the first to seven days after applying the suture in the tissue. The aim of this study was to investigate influence of a monofilament suture material (nylon) on the intensity of local tissue reaction in experimental conditions, and to compare it with the multifilament suture used in the routine practice of oral surgery (silk). This investigation is a prospective experimental study carried out on Wistar rats. The experiment included 30 animals, in which Black Silk (thickness 4-1) and Nylon (thickness 4-0) were applied in the upper and lower jaw, respectively. To monitor tissue reaction on different suture materials the following parameters were used: coagulum formation, presence of polymorphonuclear leukocytes, presence of macrophages and granuloma, formation of epithelial bridge and connective tissue, collagen synthesis, granulomatous tissue formation and presence of fibrous tissue. After comparing parameters for the intensity of tissue reaction to the investigate suture materials by suturing the oral mucosa, certain advantage could be given to the monofilament suture materials.

scholarly journals Preference of Suture Specifications in a Selected Periodontal and Implant Surgeries in Turkey

2019 ◽  
Vol 13 (01) ◽  
pp. 108-113
Author(s):  
Cenker Zeki Koyuncuoglu ◽  
Duygu Yaman ◽  
Gokhan Kasnak ◽  
Korkud Demirel
Keyword(s):  
Private Practice ◽  
Suture Material ◽  
Suture Materials ◽  
Dental Surgery ◽  
Future Studies ◽  
Mucogingival Surgery ◽  
Multiple Choice Questionnaire ◽  
Periodontal Plastic Surgery ◽  
E Mail ◽  
Selection Of

Abstract Objective Various suture materials and needles are now available for use in the dental surgery. The aim of this study was to determine the preference of suture materials among Turkish dentists by a dental survey. Materials and Methods The survey was prepared and sent electronically to Turkish dentists through e-mail and/or Facebook. Dentists were asked to report their graduation year from dental school and their specialty if they have one. In addition, the type periodontal/implant operations and the frequency of those operations applied by them were questioned. The participants were to indicate their suture preferences for these procedures in a multiple-choice questionnaire. Results Fifty-seven regular dentists, 49 periodontists, 22 oral surgeons, and 8 other specialists completed a self-administered survey. The majority of clinicians worked in private practice (77.9%). Nonabsorbable sutures were the most preferred for all procedures except periodontal plastic surgery. In regenerative surgeries, monofilament, 5–0 diameter suture material on a reverse cutting, 3/8 circle needle was preferred. In addition, for mucogingival surgery, 5–0 diameter suture material on a reverse cutting and 3/8 circle needle was favored. For dental implants, 4–0 diameter suture material on a reverse cutting and 3/8 circle needle was preferred. Monofilament and braided sutures were selected almost equally for implant operations. Conclusions In periodontal and implant surgeries, dentists highly preferred the use of nonabsorbable sutures. In addition, the shape and diameter of needle had an important role in the selection of suture material. The present study's results may serve as a guide for the future studies.

scholarly journals Evaluation of the Biocompatibility of a Recent Bioceramic Root Canal Sealer (BioRoot™ RCS): In-vivo Study

2020 ◽  
Vol 8 (D) ◽  
pp. 100-106
Author(s):  
Laila Hussein El-Mansy ◽  
Magdy Mohamed Ali ◽  
Reham EL Sayed Hassan
Keyword(s):  
Root Canal ◽  
Subcutaneous Tissue ◽  
Tissue Response ◽  
Physical Parameters ◽  
Ah Plus ◽  
Negative Controls ◽  
And Control ◽  
Root Canal Sealers ◽  
Selection Of

BACKGROUND: Recently, new calcium silicate bioceramic sealers were introduced to the market. The selection of root canal sealers should not only be based on the different physical parameters but also on local biocompatibility and tissue tolerance. AIM: This study aimed to evaluate and compare the in-vivo biocompatibility of a BioRoot RCS in parallel to MTA Fillapex and AH Plus sealers. METHODS: Polyethylene tubes containing the freshly mixed test materials were implanted in the subcutaneous tissue of 32 Wistar rats. Empty tubes served as negative controls. After 7, 14, 30, and 60 days, the animals were sacrificed, and the implants with surrounding tissues were processed for routine histological analysis. Histological sections were analyzed under light microscopy. The tissue response was determined by the inflammatory cell infiltration intensity and the fibrous capsule thickness. RESULTS: Results revealed a statistically significant decrease of the inflammation intensity by time within each group for all tested sealers and control. A well-defined thin capsule was observed for all tested sealers at 60 days. CONCLUSION: BioRoot RCS exhibited rapid recovery of inflammation similar to controls. Thus, within the limitations of this study, it can be considered a biocompatible sealer with acceptable tissue tolerance.

scholarly journals Biological Tissue Response to a New Formulation of a Silicone Based Endodontic Sealer

2016 ◽  
Vol 27 (6) ◽  
pp. 657-663 ◽  
Author(s):  
Flávia Emi Razera Baldasso ◽  
Patrícia Maria Poli Kopper ◽  
Renata Dornelles Morgental ◽  
Liviu Steier ◽  
José Antônio Poli de Figueiredo ◽  
...  
Keyword(s):  
Subcutaneous Tissue ◽  
Inflammatory Cells ◽  
Giant Cells ◽  
Negative Control ◽  
Tissue Response ◽  
Biological Behavior ◽  
Control Group ◽  
Tissue Samples ◽  
New Formulation ◽  
Post Hoc

Abstract Satisfactory biological behavior is a necessary requirement for clinical application of endodontic materials. In this study, the connective tissue responses to silicone (GuttaFlow 2), epoxy resin (AH Plus) and zinc oxide and eugenol (Endofill) based sealers were compared. Twelve Wistar rats had polyethylene tubes (four per animal) containing one of the tested sealers and empty tubes (negative control) implanted in their subcutaneous tissue. The tubes were randomly placed 2 cm from the spine and at least 2 cm apart from one another. Tissue samples with implants were processed for histological analysis after 7 or 60 days (n=6 animals per period). Inflammatory cells, fibrous condensation and abscess were scored according to their intensity. Friedman, followed by Dunn's post hoc, was used to compare sealers. Differences between the two experimental periods were verified using Mann-Witney U test (p<0.05). At 7 days, most of the histological parameters showed no significant differences amongst groups. Endofill group scored higher than the others for giant cells (o<0.05) and promoted a greater number of samples presenting abscess formation. GuttaFlow 2 tended to show a less intense inflammatory infiltrate compared to the other materials. At 60 days, there were no significant differences between groups in most of the histological parameters evaluated. However, it was observed that Endofill scored higher for macrophages (p<0.05) compared to the control group, and GuttaFlow 2 tended to present lower scores than the others for neutrophils and abscess. GuttaFlow 2 showed proper biological behavior and should be considered adequate for clinical practice.

scholarly journals Polyglactin 910 versus irradiated polyglactin 910 for subcuticular closure in elective surgeries: a randomized double-blind study

2020 ◽  
Vol 8 (1) ◽  
pp. 242
Author(s):  
Darpan Bansal ◽  
Gurpreet Singh Bhangu ◽  
Shivkaran Kaur Gill ◽  
Divya Julka
Keyword(s):  
Tensile Strength ◽  
Suture Material ◽  
Wound Dehiscence ◽  
Double Blind Study ◽  
Skin Closure ◽  
Suture Materials ◽  
Polyglactin 910 ◽  
Chi Square ◽  
Double Blind

Background: All suture materials are treated as foreign bodies and bring out a reaction in the tissues. The severity and duration of response depends on the type of suture material used. The choice of suture material is based on the concept that it should provide adequate tensile strength across the wound until tissue tensile strength has adequately developed, approximation of the epithelial portion has occurred and that the suture material should be absorbed after serving its function. this study was done to compare irradiated polyglactin 910 (Vicryl Rapide) versus polyglactin 910 (Vicryl) for subcuticular skin closure in patients of elective surgeries and to note post-operative wound inflammation, pain, dehiscence and quality of scar.Methods: 60 consecutive patients undergoing elective surgeries in department of surgery SGRD hospital were taken up for the study from April 2020 to June 2020. After randomization the subjects were divided into two groups. Subcuticular skin closure at the end of surgery was done using a 3-0 polyglactin 910 in group A and 3-0 irradiated polyglactin 910 in group B with cutting needle in both groups. Postoperatively the wound was inspected on day 3, 5, 7 and again 3 weeks after surgery.Results:  Postoperatively the wounds were observed for the signs of inflammation and infection. Each was given a wound score according to scoring system. Statistical analysis by SPSS 17.0 software and chi-square test. Irradiated polyglactin 910 showed less inflammation, pain and dehiscence along with good quality of scar as compared to polyglactin 910 on comparison.Conclusions: It was concluded that irradiated polyglactin 910 was a better choice for suture material than polyglactin 910 for subcuticular skin closure in terms of postoperative pain, wound dehiscence and quality of scar.

Absorbable suture material in carotid surgery

VASA ◽  
2015 ◽  
Vol 44 (6) ◽  
pp. 451-457 ◽  
Author(s):  
Vincenzo Gasbarro ◽  
Luca Traina ◽  
Francesco Mascoli ◽  
Vincenzo Coscia ◽  
Gianluca Buffone ◽  
...  
Keyword(s):  
Suture Material ◽  
Absorbable Suture ◽  
Paediatric Surgery ◽  
Carotid Surgery ◽  
Suture Materials ◽  
Absorbable Suture Material ◽  
Absorbable Sutures ◽  
Group A ◽  
Group B

Abstract. Background: Absorbable sutures are not generally accepted by most vascular surgeons for the fear of breakage of the suture line and the risk of aneurysmal formation, except in cases of paediatric surgery or in case of infections. Aim of this study is to provide evidence of safety and efficacy of the use of absorbable suture materials in carotid surgery. Patients and methods: In an 11 year period, 1126 patients (659 male [58.5 %], 467 female [41.5 %], median age 72) underwent carotid endarterectomy for carotid stenosis by either conventional with primary closure (cCEA) or eversion (eCEA) techniques. Patients were randomised into two groups according to the type of suture material used. In Group A, absorbable suture material (polyglycolic acid) was used and in Group B non-absorbable suture material (polypropylene) was used. Primary end-point was to compare severe restenosis and aneurysmal formation rates between the two groups of patients. For statistical analysis only cases with a minimum period of follow-up of 12 months were considered. Results: A total of 868 surgical procedures were considered for data analysis. Median follow-up was 6 years (range 1-10 years). The rate of postoperative complications was better for group A for both cCEA and eCEA procedures: 3.5 % and 2.0 % for group A, respectively, and 11.8 % and 12.9 % for group B, respectively. Conclusions: In carotid surgery, the use of absorbable suture material seems to be safe and effective and with a general lower complications rate compared to the use of non-absorbable materials.

scholarly journals Obstructive pneumonia owing to migration of a Teflon pledget at 8 years after surgery for a pulmonary carcinoid tumor: a case report

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Hikaru Watanabe ◽  
Kohei Abe ◽  
Naoki Kanauchi
Keyword(s):  
General Anesthesia ◽  
Carcinoid Tumor ◽  
Suture Material ◽  
Rare Complication ◽  
Absorbable Suture ◽  
Suture Materials ◽  
Bronchial Stump ◽  
Flexible Bronchoscope ◽  
Pulmonary Carcinoid ◽  
Bronchial Lumen

Abstract Background It is uncommon for a bronchial stump-related complication to develop during the remote postoperative period in a case of obstructive pneumonia owing to migration of the suture material. Here, we describe a case of bronchial obstructive pneumonia that developed owing to migration of the suture material in the airway 8 years after pulmonary resection. Case presentation A 34-year-old woman underwent left lower lobectomy for a pulmonary carcinoid tumor (pT1bN0M0-stage IA) in 2010. She experienced obstructive pneumonia, and chest computed tomography revealed a mass protruding from the bronchial stump to the bronchial lumen in 2018. After treatment for pneumonia, flexible bronchoscopy showed the presence of a fibrous suture material (Teflon pledget) completely obstructing the left second carina. A week later, the Teflon pledget obstructing the bronchial lumen was removed using a flexible bronchoscope with the patient under general anesthesia. The procedure was completed without removing the small amount of granulation tissue because the bronchial lumen opened after removing the Teflon pledget. She has remained asymptomatic for 1 year after removal. Conclusions In this case, the complication of obstructive pneumonia developed owing to migration of the non-absorbable suture materials used to suture the bronchial stump. Bronchoscopic management of this rare complication comprised endobronchial removal with the patient under general anesthesia. Given our experience with this case, we believe that such conservative management should allow for excellent results in most instances and avoid the need for reoperation.

Comparative Study of Tissue Response of Various Suture Materials in Rats

2002 ◽  
Vol 32 (1) ◽  
pp. 113
Author(s):  
Jae-seok Kim ◽  
Joon-Bong Park ◽  
Man-sup Lee ◽  
Yeek Herr
Keyword(s):  
Comparative Study ◽  
Tissue Response ◽  
Suture Materials
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