Divergence of Demographic Factors Associated with Clinical Severity Compared with Quality of Life Impact in Acne

2008 ◽  
Vol 12 (5) ◽  
pp. 235-242 ◽  
Author(s):  
Jerry K.L. Tan ◽  
Yudi Li ◽  
Karen Fung ◽  
Aditya K. Gupta ◽  
D. Richard Thomas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Demographic Factors ◽  
Female Gender ◽  
Male Gender ◽  
Clinical Severity ◽  
Factors Associated ◽  
Younger Age ◽  
Life Impact ◽  
Facial Acne

Background: Previous smaller studies suggest that age, gender, and duration of acne may individually be associated with clinical acne severity and quality of life (QoL) impact. Objective: Our purpose was to concurrently evaluate the association of demographic factors with clinical acne severity and with QoL impact. Methods: Clinical acne severity was assessed using the Investigators Global Assessment, whereas QoL impact was evaluated by the patient-completed Acne-QoL. These outcomes were correlated with sociodemographic variables, including age, gender, and duration of acne. Results: In 862 acne patients, clinical severity was associated with younger age, male gender, and shorter acne duration (1–5 years). In contrast, greater impact on QoL was associated with older age, female gender, and longer acne duration (> 5 years). Conclusions: Clinical and QoL measures each differentiate between groups of patients most severely affected by acne. Our findings reinforce the imperative for clinicians to use both measures for comprehensive patient management. Limitations: Study limitations include referral population of acne patients and the restriction of outcome measures to facial acne.

scholarly journals Anaemia Among Men in Malaysia: Who Are the Most Affected?

2021 ◽  
Author(s):  
S Maria Awaluddin ◽  
Nik Adilah Shahein ◽  
Norsyamlina Che Abdul Rahim ◽  
Nor Azian Mohd Zaki ◽  
Nur Hamizah Nasaruddin ◽  
...  
Keyword(s):  
Public Health ◽  
Quality Of Life ◽  
Older Men ◽  
Age Group ◽  
Factors Associated ◽  
Public Health Significance ◽  
Younger Age ◽  
Younger Men ◽  
Health Significance

Abstract This study aims to determine the prevalence of anaemia and factors associated with anaemia among men in Malaysia. Data from the National Health and Morbidity Survey 2019 was utilized. Haemoglobin level for men aged 15 years and above who gave their consent was measured using HemoCue® Hb 201+ System©. Majority of them (87.2%) were men aged 15-59 years referring to the younger age group. The prevalence of anaemia among men was 12.6% (95% confidence interval [CI]: 10.9, 14.5). Prevalence was higher in the older men (30.7%; 95% CI: 26.6, 35.1) than the younger men (10.0%; 95% CI: 8.2, 12.2). The multivariable logistic regression observed that anaemia among men was associated with older age (adjusted odds ratios [aOR] = 3.1; 95% CI: 2.1, 4.4) and those with diabetes (aOR = 1.5; 95% CI: 1.2, 2.1). Older men are more affected by anaemia than younger men. Anaemia among older men in Malaysia is considered at the level of moderate to severe public health significance and the likelihood of developing anaemia increases among older men with diabetes. These often-overlooked issues among men need to be detected and treated early to prevent complications and to improve their quality of life.

Abstract TMP101: Impact of Age at Stroke on Cognitive Outcome in Children: Selective Vulnerability of Younger Children

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Patricia Plumb ◽  
Peter L Stavinoha ◽  
Alice A Holland ◽  
Michael M Dowling
Keyword(s):  
Quality Of Life ◽  
Cognitive Outcome ◽  
Stroke Severity ◽  
Pediatric Stroke ◽  
Factors Associated ◽  
Stroke Etiology ◽  
Younger Age ◽  
The Impact

Background & Purpose: Long term cognitive deficits among pediatric stroke survivors have a significant impact on quality of life and long term functional outcome. The degree to which age at stroke relates to cognitive outcome is not clear, with some literature suggesting that younger age at stroke results in worse cognitive outcome. The present study investigated the impact of age at stroke on cognitive outcome measured by IQ in a pediatric sample with mixed stroke etiology. Methods: Subjects were 47 children (62% male) with mixed stroke etiology including sickle cell disease (23%), cardiac disease (15%), vascular disease (17%), and traumatic injury (11%) who were seen for neuropsychological evaluation as part of long-term clinical care, at which time an IQ score was obtained. Age at stroke, location, and etiology were gathered from records and considered for analysis. Results: Mean IQ for the sample was 83.68, although scores ranged from 45 to 121. There was a significant correlation between IQ and age at stroke (r = .290, p = .048), with younger age at stroke associated with lower IQ. When males and females were studied separately, this correlation was not significant for males (r = .305, p = .106) but was significant for females (r = .612, p = .007). A simultaneous linear regression model including age at stroke, gender, etiology, and stroke location significantly predicted variance in IQ (R = .543, F = 4.382, p = .005). Age at stroke and gender were the only two predictors that significantly contributed to the model. Conclusions: We found a significant correlation between stroke age and IQ, with younger stroke age associated with lower IQ. Results suggest a possible gender difference, with females in our sample more vulnerable to lower IQ as a function of younger age at stroke. Combining stroke age, gender, etiology, and stroke location accounted for a significant amount of IQ variance. Further research is necessary to clarify factors associated with outcome in survivors of pediatric stroke and should include factors such as stroke severity and socioeconomic status. Improved understanding of factors associated with cognitive outcome following pediatric stroke may inform clinical management to hopefully improve cognitive outcomes and quality of life in this population.

Socio-demographic factors associated with quality of life after a multicomponent aphasia group therapy in people with sub-acute and chronic post-stroke aphasia

Aphasiology ◽  
2020 ◽  
pp. 1-16
Author(s):  
Roxele Ribeiro Lima ◽  
Miranda L Rose ◽  
Helbert do Nascimento Lima ◽  
Ana Cristina Guarinello ◽  
Rosane Sampaio Santos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Group Therapy ◽  
Demographic Factors ◽  
Factors Associated ◽  
Post Stroke ◽  
Socio Demographic Factors

Effect of Quality of Life Impact and Clinical Severity on Adherence to Topical Acne Treatment

2009 ◽  
Vol 13 (4) ◽  
pp. 204-208 ◽  
Author(s):  
Jerry K.L. Tan ◽  
Madhan Balagurusamy ◽  
Karen Fung ◽  
Aditya K. Gupta ◽  
D. Richard Thomas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rank Correlation ◽  
Third Party ◽  
Clinical Severity ◽  
Smoking History ◽  
Acne Therapy ◽  
Chi Square Analysis ◽  
Topical Medications ◽  
Facial Acne

Background: Topical medications are the most commonly prescribed treatments for acne patients. However, adherence to these treatments and possible associations with clinical severity and quality of life (QoL) impact are unclear. Purpose: We evaluated the association between sociodemographic factors, clinical severity, and QoL impact and adherence to topical acne treatments. Methods: This was an observational study of acne patients referred for usual care to community-based dermatologists. Adherence was assessed with questionnaires after 2 months of acne therapy. The associations of adherence with factors of interest were evaluated by chi-square analysis and Spearman rank correlation. Results: In 152 acne patients treated with topical medications, low adherence was observed in 26%, medium in 49%, and high in 24%. Age, gender, duration of acne, education level, third-party drug plan coverage, smoking history, recreational drug use, ingestion of alcohol, and number of prescribed topical agents were not significantly associated with adherence. Adherence was significantly positively correlated with QoL impact ( r = .24, p = .003), with the role-emotional and self-perception domains having the highest correlations. In contrast, adherence was weakly negatively correlated with facial acne severity ( r = .16, p = .047). Limitations: This study focused on facial acne, and adherence was based on patient reporting. Conclusions: Adherence to topical acne therapy increases with impact on QoL but decreases with increasing acne severity.

scholarly journals Factors associated with quality of life in Italian children and adolescents with IBD

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Simona Gatti ◽  
Giada Del Baldo ◽  
Giulia Catassi ◽  
Andrea Faragalli ◽  
Marina Aloi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Internal Consistency ◽  
Young Patients ◽  
Female Gender ◽  
Negatively Associated ◽  
Factors Associated ◽  
Italian Children ◽  
The Impact ◽  
Active Disease

AbstractImproving the quality of life (QoL) is crucial in the management of pediatric inflammatory bowel disease (IBD). We aimed to (1) Validate the IMPACT-III questionnaire in Italian IBD children; (2) explore factors associated to QoL in pediatric IBD. Internal consistency, concurrent validity, discriminant validity and reproducibility of the Italian version of the IMPACT-III questionnaire was measured in IBD children/adolescents in 8 centers. Associations between patient and disease characteristics and the IMPACT-III domains were analyzed through quantile regression analysis. The IMPACT-III questionnaire, collected in 282 children with IBD (median age: 14.8 years; IQR 12.4–16.4) showed a median total score of 76 (IQR 67–83). Female gender, active disease and age were negatively associated with the total IMPACT-III score. Specifically, female gender was negatively associated with the Bowel/Systemic Symptoms, Emotional and Treatment domain scores, while disease activity was significantly associated with Bowel Symptoms and Treatment/Interventions reported QoL. The IMPACT- III showed good internal consistency (Cronbach’s alpha coefficient = 0.87, 95% CI 0.85–0.89) and reproducibility (Concordance Correlation Coefficient = 0.66, 95% CI 0.57–0.74). In Italian children with IBD active disease, female gender and adolescence are associated to a worse QoL, indicating the need of more attention in this subgroup of young patients. IMPACT-III questionnaire is a reliable instrument to measure QoL in Italian children.

scholarly journals Determinants of quality of life among people with epilepsy attending a secondary care rural hospita in south India

2013 ◽  
Vol 04 (S 01) ◽  
pp. S62-S66 ◽  
Author(s):  
M Ashwin ◽  
PS Rakesh ◽  
Ruby A Pricilla ◽  
K Manjunath ◽  
KS Jacob ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Secondary Care ◽  
Univariate Analysis ◽  
Female Gender ◽  
Social Consequences ◽  
Outpatient Department ◽  
World Health ◽  
Care Hospital ◽  
Factors Associated

ABSTRACT Context: Epilepsy is associated with profound physical, psychological, and social consequences. Aims : To assess the quality of life (QOL) among people with epilepsy attending the outpatient department of a secondary care hospital and to determine the various social and demographic factors affecting it. Materials and Methods: The QOL of 100 people with epilepsy attending the outpatient department of a community-based secondary care hospital was assessed using the WHOQOL-BREF (WHOQOL: World Health Organization QOL) questionnaire. Univariate analysis and logistic regression was done to determine the factors associated with poor QOL. Results: The QOL scores for all the domains ranged between 15.7 and 74.55 with a mean score of 51.49 [standard deviation (SD) 12.3]. The mean scores in the physical, psychological, social, and environmental domains were 55.7, 37.92, 57.75, and 50.56, respectively. Age more than 30 years [odds ratio (OR): 4.33, 95% confidence interval (CI): 1.73-10.82], female gender (OR: 2.90, 95% CI: 1.16-7.28), and currently married (OR: 3.82, 95% CI: 1.21-12.11) were the factors significantly associated with lower QOL scores. Conclusions: The QOL among people with epilepsy was lower in the psychological domain. Age more than 30 years, female gender, and being married were identified as the factors associated with poor QOL scores among people with seizure disorders.

scholarly journals Quality of life of adolescents with facial acne vulgaris before and after treatment in Ibadan, Nigeria

2019 ◽  
Vol 5 (1) ◽  
pp. 155
Author(s):  
Ehiaghe L. Anaba ◽  
O. O. Adebola
Keyword(s):  
Quality Of Life ◽  
Acne Vulgaris ◽  
Post Treatment ◽  
Clinical Severity ◽  
Cross Sectional ◽  
Before And After ◽  
Level Of Significance ◽  
Facial Acne ◽  
Ibadan Nigeria

<p class="abstract"><strong>Background:</strong> Adolescent facial acne vulgaris impairs their quality of life (QOL). This impairment of QOL in has been documented to improve with treatment. In Nigerian adolescents who have facial acne vulgaris, it is not known if QOL improves with treatment. The aim was to assess QOL improvement with in adolescents who have facial acne vulgaris. To identify the socio-demographic, CADI QOL items and clinical characteristics related to this QOL improvement.</p><p class="abstract"><strong>Methods:</strong> This was a cross-sectional comparative study. One hundred and nine adolescents aged 15-20 years clinically examined for facial acne vulgaris. Quality of life before and after 6 weeks of treatment with 10% benzoyl peroxide was assessed using the Cardiff acne disability index. Data was analyzed using SPSS 16. The differences in quality of life scores were tested using non-parametric tests. Level of significance of all tests was p&lt;0.05.<strong></strong></p><p class="abstract"><strong>Results:</strong> Post-treatment, the median CADI score improved to 2 from a pre-interventional score of 4, p&lt;0.001. Improvement was observed in all the components of the CADI especially with the question, “how bad do you think your acne is now” with a percentage reduction from 81.4% to 54.6% and this improvement was in more males with improvement from 92% to 65%. Also, post-treatment, moderate to severe clinical severity of acne improved from 49.1% to 10.3%, p&lt;0.001.</p><p class="abstract"><strong>Conclusions:</strong> Treatment of adolescent facial acne leads to improvement of QOL especially in the perception of facial skin appearance and the severity of acne.</p>

MALIGNANT TUMORS ASSOCIATED WITH METABOLIC SYNDROME: THE EXPRESSION PROFILE OF THE TRANSCRIPTIONAL AND GROWTH FACTORS

2017 ◽  
Vol 63 (6) ◽  
pp. 817-823
Author(s):  
Natalya Yunusova ◽  
Irina Kondakova ◽  
Sergey Afanasev ◽  
Larisa Kolomiets ◽  
Alena Chernyshova
Keyword(s):  
Quality Of Life ◽  
Metabolic Syndrome ◽  
Growth Factors ◽  
Cell Motility ◽  
Expression Profile ◽  
Malignant Tumors ◽  
Molecular Targets ◽  
Factors Associated ◽  
High Incidence

The study of the pathogenetic features of malignant tumors associated with metabolic syndrome (MS) is relevant because of high incidence of these tumors. Investigations of the mechanisms of involvement of MS in the pathogenesis of cancer reasonably supplemented by the study of transcription and growth factors associated with energy imbalance of the cell and involved in proliferation, apoptosis, angiogenesis, cell motility and inflammation. More research is needed to identify the most promising molecular targets for therapy of malignant tumors associated with MS with a view to increasing the survival and quality of life of these patients.

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