scholarly journals Automated Identification of Cephalometric Landmarks: Part 2- Might It Be Better Than human?

2019 ◽  
Vol 90 (1) ◽  
pp. 69-76 ◽  
Author(s):  
Hye-Won Hwang ◽  
Ji-Hoon Park ◽  
Jun-Ho Moon ◽  
Youngsung Yu ◽  
Hansuk Kim ◽  
...  
Keyword(s):  
Reference Points ◽  
Identification System ◽  
Learning Method ◽  
Detection Error ◽  
Hard Tissue ◽  
Automated Identification ◽  
Viable Option ◽  
The Mean ◽  
Clinically Significant ◽  
Better Than

ABSTRACT Objectives To compare detection patterns of 80 cephalometric landmarks identified by an automated identification system (AI) based on a recently proposed deep-learning method, the You-Only-Look-Once version 3 (YOLOv3), with those identified by human examiners. Materials and Methods The YOLOv3 algorithm was implemented with custom modifications and trained on 1028 cephalograms. A total of 80 landmarks comprising two vertical reference points and 46 hard tissue and 32 soft tissue landmarks were identified. On the 283 test images, the same 80 landmarks were identified by AI and human examiners twice. Statistical analyses were conducted to detect whether any significant differences between AI and human examiners existed. Influence of image factors on those differences was also investigated. Results Upon repeated trials, AI always detected identical positions on each landmark, while the human intraexaminer variability of repeated manual detections demonstrated a detection error of 0.97 ± 1.03 mm. The mean detection error between AI and human was 1.46 ± 2.97 mm. The mean difference between human examiners was 1.50 ± 1.48 mm. In general, comparisons in the detection errors between AI and human examiners were less than 0.9 mm, which did not seem to be clinically significant. Conclusions AI showed as accurate an identification of cephalometric landmarks as did human examiners. AI might be a viable option for repeatedly identifying multiple cephalometric landmarks.

scholarly journals International normalized ratio (INR) testing in Europe: between-laboratory comparability of test results obtained by Quick and Owren reagents

2018 ◽  
Vol 56 (10) ◽  
pp. 1698-1703 ◽  
Author(s):  
Piet Meijer ◽  
Karin Kynde ◽  
Antonius M.H.P. van den Besselaar ◽  
Marjan Van Blerk ◽  
Timothy A.L. Woods
Keyword(s):  
Plasma Sample ◽  
International Normalized Ratio ◽  
Test Results ◽  
Local Calibration ◽  
The Mean ◽  
The Difference ◽  
Clinically Significant ◽  
Single Plasma ◽  
Better Than

Abstract Background: This study was designed to obtain an overview of the analytical quality of the prothrombin time, reported as international normalized ratio (INR) and to assess the variation of INR results between European laboratories, the difference between Quick-type and Owren-type methods and the effect of using local INR calibration or not. In addition, we assessed the variation in INR results obtained for a single donation in comparison with a pool of several plasmas. Methods: A set of four different lyophilized plasma samples were distributed via national EQA organizations to participating laboratories for INR measurement. Results: Between-laboratory variation was lower in the Owren group than in the Quick group (on average: 6.7% vs. 8.1%, respectively). Differences in the mean INR value between the Owren and Quick group were relatively small (<0.20 INR). Between-laboratory variation was lower after local INR calibration (CV: 6.7% vs. 8.6%). For laboratories performing local calibration, the between-laboratory variation was quite similar for the Owren and Quick group (on average: 6.5% and 6.7%, respectively). Clinically significant differences in INR results (difference in INR>0.5) were observed between different reagents. No systematic significant differences in the between-laboratory variation for a single-plasma sample and a pooled plasma sample were observed. Conclusions: The comparability for laboratories using local calibration of their thromboplastin reagent is better than for laboratories not performing local calibration. Implementing local calibration is strongly recommended for the measurement of INR.

scholarly journals Peningkatan Teknik Shooting Melalui Model Pembelajaran Team Assisted Individualization (TAI)

2017 ◽  
Vol 3 (2) ◽  
pp. 154
Author(s):  
Muchamad Ishak
Keyword(s):  
Sampling Technique ◽  
Learning Model ◽  
Control Group ◽  
Cluster Sampling ◽  
Learning Method ◽  
Tenth Grade ◽  
The Mean ◽  
And Control ◽  
Experimental Group ◽  
Better Than

The intention of this research is to know the influence of Team Assisted Individualization (TAI) learning model to increase students’ shooting using instep part in football. The method of this research was experimental method. The population that was taken was the entire tenth grade students of SMK PASUNDAN 2 Cimahi consisted of 51 students. Using cluster sampling technique, it was obtained sample as many as 26 participants which were divided into two groups: experimental group (Team Assisted Individualization (TAI) learning model and control group (conventional). Based on the data analysis, students’ shooting in experiment group is better than control group (6.32 > ttable 1.80). Meanwhile, the statistical calculation showed the mean score of experiment group is bigger than control group (43.31>4.07). The conclusion is Team Assisted Individualization (TAI) learning method gives significant influence to increase students’ shooting using instep part in football.

scholarly journals Clinical Profile and Visual Outcome of Ocular Bartonellosis in Malaysia

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Chai Lee Tan ◽  
Lai Chan Fhun ◽  
Evelyn Li Min Tai ◽  
Nor Hasnida Abdul Gani ◽  
Julieana Muhammed ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Clinical Presentation ◽  
Visual Outcome ◽  
Limited Data ◽  
Viable Option ◽  
Systemic Corticosteroids ◽  
History Of ◽  
Unilateral Involvement ◽  
The Mean ◽  
Better Than

Background.Ocular bartonellosis can present in various ways, with variable visual outcome. There is limited data on ocular bartonellosis in Malaysia.Objective.We aim to describe the clinical presentation and visual outcome of ocular bartonellosis in Malaysia.Materials and Methods.This was a retrospective review of patients treated for ocular bartonellosis in two ophthalmology centers in Malaysia between January 2013 and December 2015. The diagnosis was based on clinical features, supported by a positiveBartonellaspp. serology.Results.Of the 19 patients in our series, females were predominant (63.2%). The mean age was 29.3 years. The majority (63.2%) had unilateral involvement. Five patients (26.3%) had a history of contact with cats. Neuroretinitis was the most common presentation (62.5%). Azithromycin was the antibiotic of choice (42.1%). Concurrent systemic corticosteroids were used in approximately 60% of cases. The presenting visual acuity was worse than 6/18 in approximately 60% of eyes; on final review, 76.9% of eyes had a visual acuity better than 6/18.Conclusion.Ocular bartonellosis tends to present with neuroretinitis. Azithromycin is a viable option for treatment. Systemic corticosteroids may be considered in those with poor visual acuity on presentation.

Immunologic Assessment of Patients Treated with Bovine Fibrin as a Hemostatic Agent

1996 ◽  
Vol 76 (06) ◽  
pp. 0925-0931 ◽  
Author(s):  
John F Carroll ◽  
Keith A Moskowitz ◽  
Niloo M Edwards ◽  
Thomas J Hickey ◽  
Eric A Rose ◽  
...  
Keyword(s):  
Coagulation Factors ◽  
Allergic Reactions ◽  
Factor V ◽  
Normal Range ◽  
Serum Samples ◽  
Human Fibrinogen ◽  
Bovine Thrombin ◽  
Thrombotic Complications ◽  
The Mean ◽  
Clinically Significant

SummaryTwenty-one cardiothoracic surgical patients have been treated with fibrin as a topical hemostatic/sealing agent, prepared from bovine fibrinogen clotted with bovine thrombin. Serum samples have been collected before treatment with fibrin and postoperatively between 1 and 9 days, 3 and 12 weeks, and 6 and 8 months. The titers of anti-bovine fibrinogen antibodies, measured by ELISA specific for immunoglobulins IgG or IgM, increased to maximal values after about 8 or 6 weeks, respectively. After 8 months, IgG titers were on average 20-fold lower than the mean maximal value, while IgM titers returned to the normal range. IgG was the predominant anti-bovine fibrinogen immunoglobulin as documented by ELISA, affinity chromatography and electrophoresis. Anti-bovine fibrinogen antibodies present in patients reacted readily with bovine fibrinogen, but did not cross-react with human fibrinogen as measured by ELISA or by immunoelectrophoresis. A significant amount of antibodies against bovine thrombin and factor V has been found, many cross-reacting with the human counterparts. No hemorrhagic or thrombotic complications, or clinically significant allergic reactions, occurred in any patient, in spite of antibody presence against some bovine and human coagulation factors. The treatment of patients with bovine fibrin, without induction of immunologic response against human fibrinogen, appeared to be an effective topical hemostatic/sealing measure.

THE USE OF COMMUNITY LANGUAGE LEARNINGMETHOD TO IMPROVE STUDENTS’ SPEAKING ACHIEVEMENT

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Eko Widoyo Putro ◽  
Berlin Sibarani
Keyword(s):  
Language Learning ◽  
Secondary Data ◽  
Primary Data ◽  
Second Grade ◽  
Learning Method ◽  
Field Notes ◽  
The Subject ◽  
The Mean ◽  
Method Improvement ◽  
Community Language

This study is aimed at improving the second grade of students’ speakingachievement by using Community Language Learning (CLL) Method. Theresearch was conducted by applying classroom action research. The subject of this study was second grade of Private Senior High School (Sekolah Menengah Atas Swasta) of Dwi Tunggal Tanjung Morawa which consisted of 31 students. To collect the data, the instruments used were primary data (SpeakingTest) and secondary data (interview sheet, observation sheet, field notes). It can be seen from the score in test I, test II and test III. In the Test I, the mean of the students’score was (64.77), in the Test II was (71.35), and the mean of the students’ score of the Test III was (80.90). Based on the interview, and observation sheet, it shows that the expression and excitement of the students got improved as well. It was found that teaching of speaking by using Community Language Learningcould significantly improve students’ speaking achievement.Key Words: Community Language Learning, Method, Improvement, Speaking Achievement

scholarly journals The Sankara Nethralaya Tamil Nadu Essilor Myopia (STEM) Study—Defining a Threshold for Non-Cycloplegic Myopia Prevalence in Children

2021 ◽  
Vol 10 (6) ◽  
pp. 1215
Author(s):  
Aparna Gopalakrishnan ◽  
Jameel Rizwana Hussaindeen ◽  
Viswanathan Sivaraman ◽  
Meenakshi Swaminathan ◽  
Yee Ling Wong ◽  
...  
Keyword(s):  
Open Field ◽  
Tamil Nadu ◽  
Mean Difference ◽  
School Vision ◽  
Elite School ◽  
Prevalence Estimates ◽  
The Mean ◽  
Clinically Significant ◽  
Set Up ◽  
Definition Of

The aim of this study was to investigate the agreement between cycloplegic and non-cycloplegic autorefraction with an open-field auto refractor in a school vision screening set up, and to define a threshold for myopia that agrees with the standard cycloplegic refraction threshold. The study was conducted as part of the Sankara Nethralaya Tamil Nadu Essilor Myopia (STEM) study, which investigated the prevalence, incidence, and risk factors for myopia among children in South India. Children from two schools aged 5 to 15 years, with no ocular abnormalities and whose parents gave informed consent for cycloplegic refraction were included in the study. All the children underwent visual acuity assessment (Pocket Vision Screener, Elite school of Optometry, India), followed by non-cycloplegic and cycloplegic (1% tropicamide) open-field autorefraction (Grand Seiko, WAM-5500). A total of 387 children were included in the study, of whom 201 were boys. The mean (SD) age of the children was 12.2 (±2.1) years. Overall, the mean difference between cycloplegic and non-cycloplegic spherical equivalent (SE) open-field autorefraction measures was 0.34 D (limits of agreement (LOA), 1.06 D to −0.38 D). For myopes, the mean difference between cycloplegic and non-cycloplegic SE was 0.13 D (LOA, 0.63D to −0.36D). The prevalence of myopia was 12% (95% CI, 8% to 15%) using the threshold of cycloplegic SE ≤ −0.50 D, and was 14% (95% CI, 11% to 17%) with SE ≤ −0.50 D using non-cycloplegic refraction. When myopia was defined as SE of ≤−0.75 D under non-cycloplegic conditions, there was no difference between cycloplegic and non-cycloplegic open-field autorefraction prevalence estimates (12%; 95% CI, 8% to 15%; p = 1.00). Overall, non-cycloplegic refraction underestimates hyperopia and overestimates myopia; but for subjects with myopia, this difference is minimal and not clinically significant. A threshold of SE ≤ −0.75 D agrees well for the estimation of myopia prevalence among children when using non-cycloplegic refraction and is comparable with the standard definition of cycloplegic myopic refraction of SE ≤ −0.50 D.

scholarly journals Can mean ADC value and ADC ratio of benign prostate tissue to prostate cancer assist in the prediction of clinically significant prostate cancer within the PI-RADSv2 scoring system?

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Samar Ramzy Ragheb ◽  
Reem Hassan Bassiouny
Keyword(s):  
Prostate Cancer ◽  
Sensitivity And Specificity ◽  
Gleason Score ◽  
Treatment Strategies ◽  
Serum Levels ◽  
Prostatic Tissue ◽  
Histopathological Analysis ◽  
Adc Value ◽  
The Mean ◽  
Clinically Significant

Abstract Background The aim of this study is to investigate whether quantitative DW metrics can provide additive value to the reliable categorization of lesions within existing PI-RADSv2 guidelines. Fifty-eight patients with clinically suspicious prostate cancer who underwent PR examination, PSA serum levels, sextant TRUS-guided biopsies, and bi-parametric MR imaging were included in the study. Results Sixty-six lesions were detected by histopathological analysis of surgical specimens. The mean ADC values were significantly lower in tumor than non-tumor tissue. The mean ADC value inversely correlated with Gleason score of tumors with a significant p value < 0.001.Conversely, a positive relationship was found between the ADC ratio (ADC of benign prostatic tissue to prostate cancer) and the pathologic Gleason score with a significant elevation of the ADC ratio along with an increase of the pathologic Gleason score (p < 0.001). ROC curves constructed for the tumor ADC and ADC ratio helped to distinguish pathologically aggressive (Gleason score ≥ 7) from non-aggressive (Gleason score ≤ 6) tumors and to correlate it with PIRADSv2 scoring to predict the presence of clinically significant PCA (PIRADSv2 DW ≥ 4). The ability of the tumor ADC and ADC ratio to predict highly aggressive tumors (GS> 7) was high (AUC for ADC and ADC ratio, 0.946 and 0.897; p = 0.014 and 0.039, respectively). The ADC cut-off value for GS ≥ 7 was < 0.7725 and for GS ≤ 6 was > 0.8620 with sensitivity and specificity 97 and 94%. The cutoff ADC ratio for predicting (GS > 7) was 1.42 and for GS ≤ 6 was > 1.320 with sensitivity and specificity 97 and 92%. By applying this ADC ratio cut-off value the sensitivity and specificity of reader 1 for correct categorization of PIRADSv2 DW > 4 increased from 90 and 68% to 95 and 90% and that of reader 2 increased from 94 and 88% to 97 and 92%, respectively. Conclusion Estimation of DW metrics (ADC and ADC ratio between benign prostatic tissue and prostate cancer) allow the non-invasive assessment of biological aggressiveness of prostate cancer and allow reliable application of the PIRADSv2 scoring to determine clinically significant cancer (DW score > 4) which may contribute in planning initial treatment strategies.

scholarly journals Does Every Calculation Formula Fit for All Types of Intraocular Lenses? Optimization of Constants for Tecnis ZA9003 and ZCB00 Is Necessary

Medicina ◽  
2021 ◽  
Vol 57 (4) ◽  
pp. 319
Author(s):  
Ivajlo Popov ◽  
Veronika Popova ◽  
Juraj Sekac ◽  
Vladimir Krasnik
Keyword(s):  
Prediction Error ◽  
Poor Performance ◽  
Intraocular Lenses ◽  
Power Calculation ◽  
Universal Formula ◽  
Aspheric Iol ◽  
Different Types ◽  
The Mean ◽  
Clinically Significant ◽  
Mean Prediction Error

Background and Objectives: To evaluate the performance of intraocular lenses (IOLs) using power calculation formulas on different types of IOL. Materials and Methods: 120 eyes and four IOL types (BioLine Yellow Accurate Aspheric IOL (i-Medical), TECNIS ZCB00, TECNIS ZA9003 (Johnson & Johnson) (3-piece IOL) and Softec HD (Lenstec)) were analyzed. The performance of Haigis, Barret Universal II and SKR-II formulas were compared between IOL types. The mean prediction error (ME) and mean absolute prediction error (MAE) were analyzed. Results: The overall percentage of eyes predicted within ±0.25 diopters (D) was 40.8% for Barret; 39.2% Haigis and 31.7% for SRK-II. Barret and Haigis had a significantly lower MAE than SRK-II (p < 0.05). The results differed among IOL types. The largest portion of eyes predicted within ±0.25 D was with the Barret formula in ZCB00 (33.3%) and ZA9003 (43.3%). Haigis was the most accurate in Softec HD (50%) and SRK-II in Biolline Yellow IOL (50%). ZCB00 showed a clinically significant hypermetropic ME compared to other IOLs. Conclusions: In general, Barret formulas had the best performance as a universal formula. However, the formula should be chosen according to the type of IOL in order to obtain the best results. Constant optimizations are necessary for the Tecnis IOL ZCB00 and ZA9003, as all of the analyzed formulas achieved a clinically significant poor performance in this type of IOL. ZCB00 also showed a hypermetropic shift in ME in all the formulas.

Quantitative analysis of static equilibrium in women after mastectomy

2014 ◽  
Vol 14 (1) ◽  
pp. 81-87
Author(s):  
Maciej Rachwał ◽  
Justyna Drzał-Grabiec ◽  
Katarzyna Walicka-Cupryś ◽  
Aleksandra Truszczyńska
Keyword(s):  
Mean Amplitude ◽  
Control Group ◽  
Foot Pressure ◽  
Locomotor System ◽  
Center Of Foot Pressure ◽  
The Mean ◽  
Almost All ◽  
Posture Stability ◽  
Mastectomy Group ◽  
Better Than

Abstract Background: The post-mastectomy changes to the locomotor system are related to the scar and adhesion or to the lymphatic edema after amputation which, in turn, lead to local and global distraction of the work of the muscles. These changes lead to body statics disturbance that changes the projection of the center of gravity and worsens motor response due to changing of the muscle sensitivity. Objective: The aim of the study was to evaluate the static balance of women after undergoing mastectomy. Methods: The study included 150 women, including 75 who underwent mastectomy (mean age: 60±7.6) years, mean body mass index (BMI): 26 (±3.6) kg/m2) and 75 who were placed in the control group with matched age and BMI. The study was conducted using a tensometric platform. Results: Statistically significant differences were found for almost all parameters between the post-mastectomy group and group of healthy women, regarding center of foot pressure (COP) path length in the Y and X axes and the mean amplitude of COP. Conclusions: First, the findings revealed that balance in post-mastectomy women is significantly better than in the control group. Second, physiotherapeutic treatment of post-mastectomy women may have improved their posture stability compared with their peers.

scholarly journals Heterobeltiosis in French Marigold (Tagetes patula L.)

2016 ◽  
Vol 8 (8) ◽  
pp. 182
Author(s):  
Kanwar Priyanaka ◽  
Y. C. Gupta ◽  
S. R. Dhiman ◽  
R. K. Dogra ◽  
Sharma Madhu ◽  
...  
Keyword(s):  
Rainy Season ◽  
Quantitative Traits ◽  
Block Design ◽  
Tagetes Patula ◽  
Male Sterile ◽  
Randomized Block Design ◽  
Parental Material ◽  
The Mean ◽  
Parental Lines ◽  
Better Than

<p>The studies on heterosis were carried with four male sterile lines namely; ms<sub>7</sub>, ms<sub>8</sub>, ms<sub>9,</sub> ms<sub>10</sub> and 18 diverse pollinators as tester by using line × tester crossing programme. The 72 F<sub>1</sub> hybrids were produced and evaluated along with 22 parental lines during summer 2009 and rainy season 2009 in Randomized Block Design. Observations were recorded on nine quantitative traits during both the seasons. Highly significant variances for all the traits indicated the sufficient variability in the parental material for all the characters under study. The performance of F<sub>1</sub> hybrids was much better than the mean performance of parents during both the crop seasons. Appreciable heterosis was observed in all the characters, except flower weight in summer and plant height in rainy season.</p>

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