scholarly journals The reliability and reproducibility of an Android cephalometric smartphone application in comparison with the conventional method

2020 ◽  
Author(s):  
Obada M. Zamrik ◽  
Haluk İşeri
Keyword(s):  
Conventional Method ◽  
Pearson Correlation ◽  
Correlation Coefficients ◽  
Smartphone Application ◽  
Linear Measurement ◽  
Significant Difference ◽  
The Difference ◽  
Clinically Significant ◽  
Mean Differences ◽  
Tracing Techniques

ABSTRACT Objectives To assess the reliability and reproducibility of linear and angular measurements of the cephalometric smartphone Android application OneCeph in comparison with the conventional method. Materials and Methods A total number of 22 landmarks were registered, and 26 skeletal and dental cephalometric parameters were measured on 30 pretreatment cephalograms. The measurements for both digital (OneCeph) and conventional tracings were performed twice with a 4-week interval. The reliability (intraexaminer error) was evaluated by using the Pearson correlation coefficient. The variation in measurements between the tracing techniques (reproducibility) was determined by paired t-test. Results The Pearson correlation coefficients of all cephalometric measurements for each tracing technique were ≥ 0.95. Significant differences between the two tracing techniques were detected in five measurements (SNB angle, N I to Pog linear measurement, U1-Apoint linear measurement, U lip to S line, and nasiolabial angle; P < .05). Conclusions Using 26 measurements to compare both tracing methods, all mean differences between the digital (OneCeph) and conventional methods were below 1 degree/1 mm, indicating that differences between the tracing methods were clinically insignificant. The U1-A point measurement was an exception for the digital method (OneCeph) with a clinically significant difference of 1.25 mm (P < .01); the difference was a result of wrongly measuring the distance from the A line to the incisor edge of the upper central incisor rather than the facial surface of the upper incisor. This leads to the conclusion that both tracing methods were reliable for daily clinical practice.

Comparison of ACT point-of-care measurements: repeatability and agreement

Perfusion ◽  
2006 ◽  
Vol 21 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Y PJ Bosch ◽  
Y M Ganushchak ◽  
D S de Jong
Keyword(s):  
Point Of Care ◽  
Pearson Correlation ◽  
Correlation Coefficients ◽  
Clotting Time ◽  
Time Data ◽  
P Values ◽  
Activated Clotting Time ◽  
Significant Difference ◽  
Before And After ◽  
Mean Differences

Background: Accurate control of heparin anticoagulation is necessary during all stages of cardiopulmonary bypass (CPB). The activated clotting time, first described by Hattersley in 1966, is mostly used for determination of anticoagulation. Either celite or kaolin are used as activators. An ACT value of 480 sec is proposed to be the safe minimum level for anticoagulation during CPB. This study was designed to determine if the activated coagulation time (ACT) values of each analyser separately are repeatable, and to determine whether there exists a significant difference in ACT values measured by three different analysers: the GEM PCL (Instrumentation Laboratory), the Hemochron 801 (International Techni-dyne Corporation) and the ACT II Automated Coagulation Timer (Medtronic). Methods: All patients underwent cardiovascular surgical procedures requiring heparinisation (200 - 300 IU/kg). Blood samples for the measurement of the ACT were taken from all patients before and after heparinisation, during CPB, and after protamine administration. All samples were measured in duplicate with the three different analysers. To compare the activated clotting time data, the method described by Bland and Altman was used. The Pearson correlation coefficient was used to determine whether the differences were related to the average ACTs. p-Values < 0.05 were considered statistically significant. Results: The results showed that the three tested ACT analysers met the requirements of repeatability. The mean differences and standard deviations of the ACT values measured with the GEM PCL, the Hemochron 801, and the ACT II analyser were, respectively, -8.789 ± 37.61, -19.779±68.82, and -6.239±39.21, with p-values=0.177, 0.081 and 0.384, respectively. The Pearson correlation coefficients were too low (-0.012, -0.221 and -0.241, respectively) to show any correlation between the differences and the means. The ACT values measured with the Hemochron 801 were not significantly different from the ACT values measured with the ACT II analyser: ΔACT=-34.09 ± 146.68, with p=0.132. However, the GEM PCL did not agree with the Hemochron 801: ΔACT=-80.29 ± 143.06, with p=0.001, or the ACT II analyser: ΔACT=-119.139 ± 138.51, with p<0.001. A rather strong correlation was evident between the differences and the means measured with the GEM PCL compared with the Hemochron 801 (r=0.68) and the ACT II analyser (r=0.76). Conclusions: All analysers used celite or kaolin as activator. However, it was evident that the ACT measurements depended also on the analyser that had been chosen. A precaution that ACT values could not always be interpreted in the same way seems to be necessary.

4971Blood viscosity and its relevance to the diagnosis and management of pulmonary hypertension: a new elephant in the cathlab

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A Kempny ◽  
K Dimopoulos ◽  
A E Fraisse ◽  
G P Diller ◽  
L C Price ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Cardiac Catheterization ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Pulmonary Vasculature ◽  
Pulmonary Vascular Disease ◽  
Significant Difference ◽  
The Difference ◽  
Clinically Significant ◽  
The Relationship

Abstract Background Pulmonary vascular resistance (PVR) is an essential parameter assessed during cardiac catheterization. It is used to confirm pulmonary vascular disease, to assess response to targeted pulmonary hypertension (PH) therapy and to determine the possibility of surgery, such as closure of intra-cardiac shunt or transplantation. While PVR is believed to mainly reflect the properties of the pulmonary vasculature, it is also related to blood viscosity (BV). Objectives We aimed to assess the relationship between measured (mPVR) and viscosity-corrected PVR (cPVR) and its impact on clinical decision-making. Methods We assessed consecutive PH patients undergoing cardiac catheterization. BV was assessed using the Hutton method. Results We included 465 patients (56.6% female, median age 63y). The difference between mPVR and cPVR was highest in patients with abnormal Hb levels (anemic patients: 5.6 [3.4–8.0] vs 7.8Wood Units (WU) [5.1–11.9], P<0.001; patients with raised Hb: 10.8 [6.9–15.4] vs. 7.6WU [4.6–10.8], P<0.001, respectively). Overall, 33.3% patients had a clinically significant (>2.0WU) difference between mPVR and cPVR, and this was more pronounced in those with anemia (52.9%) or raised Hb (77.6%). In patients in the upper quartile for this difference, mPVR and cPVR differed by 4.0WU [3.4–5.2]. Adjustment of PVR required Conclusions We report, herewith, a clinically significant difference between mPVR and cPVR in a third of contemporary patients assessed for PH. This difference is most pronounced in patients with anemia, in whom mPVR significantly underestimates PVR, whereas in most patients with raised Hb, mPVR overestimates it. Our data suggest that routine adjustment for BV is necessary.

scholarly journals Assessment of necessity of neuronavigation in localization of calvarial extra-axial lesions in the setting of limited resources

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Hussein Soffar ◽  
Mohamed F. Alsawy
Keyword(s):  
Conventional Method ◽  
Linear Measurement ◽  
Limited Resources ◽  
Linear Measurements ◽  
Surgical Interventions ◽  
Localization Method ◽  
Mean Error ◽  
Significant Difference ◽  
The Mean ◽  
Mean Time

Abstract Background Neuronavigation is a very beneficial tool in modern neurosurgical practice. However, the neuronavigation is not available in most of the hospitals in our country raising the question about its importance in localizing the calvarial extra-axial lesions and to what extent it is safe to operate without it. Methods We studied twenty patients with calvarial extra-axial lesions who underwent surgical interventions. All lesions were preoperatively located with both neuronavigation and the usual linear measurements. Both methods were compared regarding the time consumed to localize the tumor and the accuracy of each method to anticipate the actual center of the tumor. Results The mean error of distance between the planned center of the tumor and the actual was 6.50 ± 1.762 mm in conventional method, whereas the error was 3.85 ± 1.309 mm in IGS method. Much more time was consumed during the neuronavigation method including booting, registration, and positioning. A statistically significant difference was found between the mean time passed in the conventional method and IGS method (2.05 ± 0.826, 24.90 ± 1.334, respectively), P-value < 0.001. Conclusion In the setting of limited resources, the linear measurement localization method seems to have an accepted accuracy in the localization of calvarial extra-axial lesions and it saves more time than neuronavigation method.

Attention Deficit Hyperactivity Disorder, Creativity, and the Effects of Methylphenidate

PEDIATRICS ◽  
1993 ◽  
Vol 91 (4) ◽  
pp. 816-819
Author(s):  
Jeanne B. Funk ◽  
John B. Chessare ◽  
Michael T. Weaver ◽  
Anita R. Exley
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Repeated Measures ◽  
Creative Thinking ◽  
Adhd Group ◽  
Hyperactivity Disorder ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Difference ◽  
Clinically Significant

Given that children with attention deficit hyperactivity disorder (ADHD) are more impulsive than peers, this study explored whether they are correspondingly more creative, and whether creativity declines when impulsivity is decreased through methylphenidate (Ritalin) therapy. A repeated-measures quasi-experimental design was used to compare the performance of 19 boys with previously diagnosed ADHD and 21 comparison boys aged 8 through 11 on two administrations of alternate forms of the Torrance Tests of Creative Thinking-Figural (nonverbal). Boys with ADHD received prescribed methylphenidate only for the first session. Overall, mean Torrance summary scores for comparison boys (mean = 115.1, SD = 16.1) were higher than for boys with ADHD (mean = 107.6, SD = 12.7). However, the difference between means was small (7%) and did not meet the 25% criterion for a clinically significant difference. No changes in performance over time (comparison group) or medication state (ADHD group) were observed. These data suggest that, when measured nonverbally, the creative thinking performance of boys with ADHD is not superior to that of peers who do not have ADHD. Regarding the effects of methylphenidate, prescribed therapy did not influence performance on this measure of creative thinking.

scholarly journals A Comparison Between Two Types of Radiographic Film for Accuracy of Measurements of Approximal Osseous Defects

2006 ◽  
Vol 7 (3) ◽  
pp. 22-29
Author(s):  
Farah Masood ◽  
Christos Angelopoulos ◽  
Alan Glaros
Keyword(s):  
Bone Loss ◽  
Ground Truth ◽  
Radiographic Film ◽  
Radiographic Images ◽  
Accuracy Of Measurements ◽  
Significant Difference ◽  
Molar Teeth ◽  
The Difference ◽  
Clinically Significant ◽  
Osseous Defects

Abstract Aim The purpose of this study was to compare two types of conventional radiographic film: Ekta-speed plus and Insight (Eastman Kodak Co, Rochester NY, USA) for accuracy of measurements of approximal bone loss. Methods and Materials Four dried human mandibles with complete dentition were selected. Radiographic images were made with a standardized technique. Mesial and distal bone levels on the mandibular premolar and molar teeth were measured on the two types of radiographs (Ekta-speed plus and Insight) by nine observers. The data obtained by the observers were compared with the primary investigators’ corresponding measurements, which served as “the ground truth” for this study. Results The results of the analysis of variance (ANOVA) demonstrated a significant difference for the Ektaspeed plus film (p = .001), but the difference was not clinically significant. The level of intra-rater reliability was high for the observers (0.969 to 0.990). Conclusion Performance of Ekta-speed plus and Insight films was found to be similar. Citation Masood F, Angelopoulos C, Glaros A. A Comparison Between Two Types of Radiographic Film for Accuracy of Measurements of Approximal Osseous Defects. J Contemp Dent Pract 2006 July;(7)3:022-029.

Q-TWiST analysis of tivozanib (T) versus sorafenib (S) in patients with advanced renal cell carcinoma (RCC) in the TIVO-3 study.

2021 ◽  
Vol 39 (6_suppl) ◽  
pp. 298-298
Author(s):  
Michael Szarek ◽  
Michael N. Needle ◽  
Brian I. Rini ◽  
Sumanta K. Pal ◽  
David F. McDermott ◽  
...  
Keyword(s):  
Progression Free Survival ◽  
Phase Iii ◽  
P Value ◽  
Patient Centered ◽  
Health States ◽  
Significant Difference ◽  
Phase Iii Study ◽  
The Difference ◽  
Similar Survival ◽  
Mean Differences

298 Background: In the randomized phase III study TIVO-3, the VEGFR-TKI tivozanib (TIVO) increased progression-free survival with better tolerability but no difference in overall survival (OS) relative to sorafenib (SORA) as third- or fourth-line therapy in patients with metastatic RCC. These results provide motivation to apply quality-adjusted time without symptoms of disease and toxicity (Q-TWiST) methods to quantify the net health benefits of TIVO, in the presence of similar survival, when compared to SORA. Methods: In application of Q-TWiST, patient-level OS was subdivided into three mutually exclusive states: time with toxicity (TOX), time without symptoms and toxicity (TWiST), and time after progression/relapse (REL). Mean Q-TWiST was calculated by applying utility coefficients of 0.5, 1.0, and 0.5 to the restricted mean (max 36 months follow-up) health states of TOX, TWiST, and REL, respectively; 95% CIs for the means and mean differences were estimated by bootstrap distributions. Relative Q-TWiST gain was defined as the mean absolute Q-TWiST difference divided by the SORA mean OS. Results: Mean TWiST was significantly longer for TIVO than for SORA (10.30 months v.5.35 months; Table). Mean REL time was significantly shorter for TIVO, with no difference in mean TOX time. Mean Q-TWiST was 15.04 and 12.78 months for TIVO and SORA, respectively, a statistically significant difference (p=0.0493). The relative gain for TIVO was 11.2%. Clinical trial information: NCT02627963 . Values in table are mean (95% CI) in months or p-value for difference in treatment group means. Conclusions: The difference in Q-TWiST in TIVO-3 was primarily driven by benefits of TIVO in TWiST, partially offset by superiority of SORA in REL time. As a third- or fourth-line treatment for RCC, TIVO significantly increased Q-TWiST relative to SORA, primarily through an increase in TWiST, which is generally considered to be the state with highest utility to patients. Consequently, Q-TWiST may be considered an alternative patient-centered measure of benefit of TIVO in these settings. [Table: see text]

scholarly journals A Comparative Study of Clinical vs. Digital Exophthalmometry Measurement Methods

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Tháıs de Sous Pereira ◽  
Cristina Hiromi Kuniyoshi ◽  
Cristiane de Almeida Leite ◽  
Eloisa M. M. S. Gebrim ◽  
Mário L. R. Monteiro ◽  
...  
Keyword(s):  
Ct Scan ◽  
Pearson Correlation ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Measurement Methods ◽  
Gold Standard Method ◽  
Mean Values ◽  
Ct Measurements ◽  
Mean Differences ◽  
No Gold Standard

Background. A number of orbital diseases may be evaluated based on the degree of exophthalmos, but there is still no gold standard method for the measurement of this parameter. In this study we compare two exophthalmometry measurement methods (digital photography and clinical) with regard to reproducibility and the level of correlation and agreement with measurements obtained with Computerized Tomography (CT) measurements. Methods. Seventeen patients with bilateral proptosis and 15 patients with normal orbits diseases were enrolled. Patients underwent orbital CT, Hertel exophthalmometry (HE) and standardized frontal and side facial photographs by a single trained photographer. Exophthalmometry measurements with HE, the digital photographs and axial CT scans were obtained twice by the same examiner and once by another examiner. Pearson correlation coefficient (PCC) was used to assess correlations between methods. Validity between methods was assessed by mean differences, interintraclass correlation coefficients (ICC’s), and Bland–Altman plots. Results. Mean values were significantly higher in the proptosis group (34 orbits) than in the normal group (30 orbits), regardless of the method. Within each group, mean digital exophthalmometry measurements (24.32 ± 5.17 mm and 18.62 ± 3.87 mm) were significantly greater than HE measurements (20.87 ± 2.53 mm and 17.52 ± 2.67 mm) with broader range of standard deviation. Inter-/intraclass correlation coefficients were 0.95/0.93 for clinical, 0.92/0.74 for digital, and 0.91/0.95 for CT measurements. Correlation coefficients between HE and CT scan measurements in both groups of subjects (r = 0.84 and r = 0.91, p<0.05) were greater than those between digital and CT scan measurements (r = 0.61 and r = 0.75, p<0.05). On the Bland–Altman plots, HE showed better agreement to CT measurements compared to the digital photograph method in both groups studied. Conclusions. Although photographic digital exophthalmometry showed strong correlation and agreement with CT scan measurements, it still performs worse than and is not as accurate as clinical Hertel exophthalmometry. This trail is registered with NCT01999790.

scholarly journals Does the Symmetry of Patellar Morphology Matter When Matching Osteochondral Allografts for Osteochondral Defects Involving the Central Ridge of the Patella?

2020 ◽  
Vol 8 (7_suppl6) ◽  
pp. 2325967120S0044
Author(s):  
Nabeel Salka ◽  
Austin Ramme ◽  
John Grant ◽  
Jaron Scott ◽  
Karan Patel
Keyword(s):  
Surface Morphology ◽  
Pearson Correlation ◽  
Random Number Generator ◽  
Patellar Height ◽  
Osteochondral Defects ◽  
Surface Mapping ◽  
Significant Difference ◽  
Central Ridge ◽  
Clinically Significant ◽  
Osteochondral Allografts

Objectives: Osteochondral allografts of the patellar are currently matched solely based on tibial width. It is currently unknown whether matching by tibial width is a reasonable surrogate measurement to allow for optimum chondral surface matching or if patellar size and/or surface morphology (i.e., Wiberg classification) should be taken into account. This consideration may be especially important for chondral defects on the patellar apex. The purpose of this study was to use circumferential step-off height and chondral surface mapping to determine if differences in patellar surface morphology (i.e., Wiberg classification) play a role in the ability of donor patellar osteochondral allografts to match the native patellar surface when treating osteochondral defects involving the central ridge of the patella. The secondary purpose was to explore the relationship between tibial width and patellar size (width and height) to determine if tibial width strongly related to patellar size to allow it to act as a surrogate measure for patellar size. Methods: Twenty (10 Wiberg I and 10 Wiberg II/III) fresh frozen patellae were designated as the recipient. Each recipient was size-matched (within ± 2mm tibial width) to both a Wiberg I and a Wiberg II/III patellar donor to produce 20 size-matched trios. All patellas were classified as Wiberg I, II, or III by visual inspection. The patellar height and widths were also measured. The recipient patella underwent initial nanoCT scanning to quantify the native chondral surface morphology. A 16mm circular osteochondral “defect” centered on the central ridge of the patella was then created in the recipient patella. Within each set of three patellae, the donor Wiberg I and Wiberg II/III patellae were randomly assigned, using a random number generator, to be transplanted first or second. The randomly ordered donor Wiberg I or Wiberg II/III plug was harvested from a homologous location and transplanted into the recipient. The recipient was then nano-CT scanned, digitally reconstructed, registered to the initial nano-CT scan of the recipient patella. It was then processed in Dragon Fly to determine circumferential step-off heights between the native and donor surfaces at three degree intervals. This was calculated for the entire circumference and for each quadrant (superior, medial, inferior, lateral) to determine if the ste-off heights varied by locations. MATLAB was used to determine the height deviation (dRMS) between the native and donor surfaces at over 3000 surface points (Figure 1). The initial transplant was carefully removed and the process was then repeated for the other donor allograft. Pearson correlation coefficient, 2-way ANOVA with Tukey’s multiple comparison, and paired t-tests were used when appropriate. Sample size of 10 trios was determined based on previous work in our lab (clinically relevant difference of 0.75mm, SD = 0.5mm, α = 0.05, power 0.8; 7 samples per group). Results: There was no significant difference in mean step-off heights between matched and unmatched Wiberg allograft plugs (Table 1). When analyzing all patellas, the superior (p = 0.01) and lateral (p = 0.001) quadrants demonstrated step-off heights that were significantly greater compared to the inferior quadrant, however these findings were not clinically significant. There was a statistically significant difference in height deviation over the whole surface between native and donor plugs when comparing matched and unmatched Wiberg plugs (p=0.049), however this finding was not clinically significant (Table 2). There was no difference across individual quadrants. There was a linear correlation when comparing tibial width to patellar width (r = 0.82) and patellar height (r = 0.68). Conclusions: Differences in Wiberg classification did not lead to clinically relevant differences in step-off height or surface height deviations for the whole donor plug or by quadrant. Tibial width is a reasonable measure to predict patellar size (width and height). It is therefore reasonable to continue matching osteochondral allografts of the patella based on the easy to measure value of tibial width without consideration for patellar size or Wiberg classification. [Table: see text][Table: see text]

scholarly journals Validation of protein and potassium intakes assessed from 24 h recalls against levels estimated from 24 h urine samples in children and adolescents of Turkish descent living in Germany: results from the EVET! Study

2011 ◽  
Vol 15 (4) ◽  
pp. 640-647 ◽  
Author(s):  
Beate Bokhof ◽  
Anette E Buyken ◽  
Canan Doğan ◽  
Arzu Karaboğa ◽  
Josa Kaiser ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Urine Sample ◽  
Dietary Habits ◽  
Pearson Correlation ◽  
Correlation Coefficients ◽  
Assessment Tools ◽  
Nutritional Intake ◽  
Cross Sectional ◽  
Mean Differences ◽  
Study Participants

AbstractObjectiveNutrition-related health problems such as obesity are frequent among children and adolescents of Turkish descent living in Germany, yet data on their dietary habits are scarce. One reason might be the lack of validated assessment tools for this target group. We therefore aimed to validate protein and K intakes from one 24 h recall against levels estimated from one 24 h urine sample in children and adolescents of Turkish descent living in Germany.DesignCross-sectional analyses comprised estimation of mean differences, Pearson correlation coefficients, cross-classifications and Bland–Altman plots to assess the agreement between the nutritional intake estimated from a single 24 h recall and a single 24 h urine sample collected on the previous day.SettingDortmund, Germany.SubjectsData from forty-three study participants (aged 5–18 years; 26 % overweight) with a traditional Turkish background were included.ResultsThe 24 h recall significantly overestimated mean protein and K intake by 10·7 g/d (95 % CI of mean difference: 0·6, 20·7 g/d) and 344 mg/d (95 % CI 8, 680 mg/d), respectively. Correlations between intake estimates were r = 0·25 (P = 0·1) and 0·31 (P = 0·05). Both methods classified 70 % and 69 % of the participants into the same/adjacent quartile of protein and K intake and misclassified 7 % and 7 %, respectively, into the opposite quartile. Bland–Altman plots indicated a wide scattering of differences in both protein and K intake.ConclusionsAmong children and adolescents of traditional Turkish descent living in Germany, one 24 h recall may only be valid for categorizing subjects into high, medium or low consumers.

scholarly journals Correlation of VIT D3 and serum ferritin levels in anemic patients in a hospital based study.

2020 ◽  
Vol 27 (11) ◽  
pp. 2376-2382
Author(s):  
Hamzullah Khan ◽  
Mohammad Basharat
Keyword(s):  
Serum Ferritin ◽  
Standard Error ◽  
Ferritin Level ◽  
Pearson Correlation ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Iron Deficient ◽  
Significant Difference ◽  
The Difference ◽  
Gender Groups

Objectives: To determine the correlation of Vit D3 levels with serum ferritin in patients with anemia. Study Design: Cross Sectional study. Setting: Department of Pathology, Qazi Hussain Ahmed Medical Complex Nowshera. Period: 5th Jan 2019 to 31st Dec 2020. Material & Methods: Data entered in SPSS 25th version. Descriptive statistics was used for numerical variables. Pearson correlation was used for correlation of Vit D3 with gender. Normality of data was checked by Shapiro wilk test. Mann Whitney U test was used to show the difference of Vit D3 and ferritin levels in gender. Results: The total of 192 anemic patients with Hb<10g/dl as per definition of WHO1 were referred for ferritin level estimation with 142(74%) females and 50(26%) males. Out of total, 47 were also advised with Vit D3 level estimation with 29(61.7%) females and 18(38.3%) males. Mean with standard deviation for age was 30+9.6 years. Mean with standard Error of mean of Vit D3 was (Mean-15.5ng/ml, SE 2.19). Mean with standard Error of mean of serum ferritin was (Mean-48.2ng/ml, SE 5.90). We observed 35(74.5%) cases out of 47, as Vit D3 deficient with a count less than 20 ng/ml. We observed that 118 (61.5%) were iron deficient with serum ferritin less than 15ng/ml. Person correlation showed a statistically significant correlation of Vit D3 with ferritin (p= 0.022, r=0.7). Spearman ranked correlation showed a statistically significant correlation between the categories of Vit D3 and ferritin (p=0.022, r=0.7). Mann Whitney U Test showed no significant difference in gender groups for botht the variables (p= 0.86 &p=0.33 respectively) thus retain the null hypotheses. Conclusion: The frequency of deficiency Vit D3<20ng/ml in anemic patients was 74% while that of ferritin<15ng/ml in anemic patients was 61.5%. There is a strong statistically significant correlation of Vit D3 with serum ferritin in anemic patients with Hb<11g/dl.

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