scholarly journals Is the Patent System the Way Forward with the CRISPR-Cas 9 Technology?

2020 ◽  
Vol 33 (4) ◽  
pp. 2-23
Author(s):  
Franc Mali
Keyword(s):  
Genetic Engineering ◽  
Scientific Discovery ◽  
Human Life ◽  
New Technology ◽  
Basic Research ◽  
Scientific Institutions ◽  
Patent Landscape ◽  
Central Argument ◽  
Over 40 Years ◽  
The Way

CRISPR-Cas9 technology is reshaping the way scientists conduct research in genetic engineering. It is predicted to revolutionise not only the fields of medicine, biology, agriculture and industry but, much like all revolutionary technologies of the past, the way humans live. Given the anticipated and already seen benefits of CRISPR-Cas 9 in different areas of human life, this new technology may be defined as a true breakthrough scientific discovery. The article presents several challenges connected with various dimensions of the CRISPR-Cas 9 patent landscape. The central argument is that today the biggest challenge is finding a intermediary way that ensures a balance between providing sufficient openness for the further progress of basic research in CRISPR-Cas 9 such as ‘niche’ areas of the latest genetic engineering and adequate intellectual property rights to incentivise its commercialisation and application. The article contends the endeavours by academic scientific institutions to arrive at short-term benefits of the new CRISPR-Cas 9 technology do not constitute such an intermediary way, especially when the CRISPR-Cas 9 patent landscape is viewed as part of a series of controversial bioethical discussions that have been underway for over 40 years.

Design Capability for Science-based Innovation

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
ROTHKÖTTER Stefanie ◽  
Craig C. GARNER ◽  
Sándor VAJNA
Keyword(s):  
Literature Review ◽  
Scientific Discovery ◽  
New Technology ◽  
Academic Research ◽  
Research Interest ◽  
Design Practice ◽  
Design Technology ◽  
Innovation Potential ◽  
Design Integration ◽  
Cultural Constraints

In light of a growing research interest in the innovation potential that lies at the inter­section of design, technology, and science, this paper offers a literature review of design initiatives centered on scientific discovery and invention. The focus of this paper is on evidence of design capabilities in the academic research environment. The results are structured along the Four Orders of Design, with examples of design-in-science initiatives ranging from (1) the design of scientific figures and (2) laboratory devices using new technology to (3) interactions in design workshops for scientists and (4) inter­disciplinary design labs. While design capabilities have appeared in all four orders of design, there are barriers and cultural constraints that have to be taken into account for working at or researching these creative intersections. Modes of design integration and potentially necessary adaptations of design practice are therefore also highlighted.

First as Sociology, Then as Geography

2015 ◽  
Vol 44 (1) ◽  
pp. 39-43
Author(s):  
Justin Tse
Keyword(s):  
Social Geography ◽  
New Age ◽  
Religious Studies ◽  
Critical Geography ◽  
Social Fact ◽  
Central Argument ◽  
Ideological Work ◽  
The Way

This essay reviews Steven J. Sutcliffe and Ingvild Sælid Gilhus's New Age Spiritualities: Rethinking Religion. It shows that their attempt to redefine religion through new age spiritualities is actually an attempt to impose an economically elite social geography onto religious studies as a social fact. My central argument is that this effort in turn reveals that religious studies serves as a sociological factory for liberal economic ideologies. It suggests that to mitigate this ideological work, a shift toward critical geography in religious studies is the way forward.

Un Dieu sadique : le rôle de l’image blasphématoire de Dieu dans Dolce agonia de Nancy Huston

2013 ◽  
pp. 160-166
Author(s):  
Izabela Front
Keyword(s):  
Present Article ◽  
Human Life ◽  
Character Of God ◽  
Double Character ◽  
The Way

The present article seeks to analyze the way in which the blasphemous figure of God in Dolce agonia by Nancy Huston allows the author to describe the sacred element in human life, seen as deprived of transcendental character. This is possible thanks to the three aspects of the text dependent on the type of God’s figure, which are: the contrast between passages marked by the cynical God’s voice and passages focused on man’s life filled with suffering; the tone and the appropriation of time var-iations and, finally, the double character of God who, at the same time, is indifferent to man’s lot while touched by his capacity of love.

Redesigning Life

2020 ◽  
Author(s):  
John Parrington
Keyword(s):  
Genetic Engineering ◽  
The World ◽  
The Future ◽  
Synthetic Organisms ◽  
The Way

We can now edit genomes. The technique, which involves cutting and pasting DNA code into the genome, is faster and cheaper than traditional genetic engineering and can be used on almost any animal or plant. What will this technology mean for the future? It may pave the way to banishing many diseases, and help feed the burgeoning population of the world. Woolly mammoths may again roam the tundra. But are there also risks? Might a nightmarish world of bioterrorism and rogue synthetic organisms await? John Parrington reports on the astonishing revolution underway in genetic engineering and why it matters to us all.

Beauty, Morality, and the Promise of Happiness

2017 ◽  
Author(s):  
Sarah Stewart-Kroeker
Keyword(s):  
Human Life ◽  
Iris Murdoch ◽  
Fundamental Feature ◽  
The Way

This chapter takes up the themes of Chapter 3—loving beauty’s formative power—in a dialogue with contemporary philosophers Alexander Nehamas and Elaine Scarry, as well as with (to a lesser extent) Iris Murdoch. It explores the nature of love, beauty, and morality through a dialogue across historical–contemporary, theological–philosophical lines. A number of prominent modern criticisms of Augustine focus on a fundamental feature of his thought: that everything in human life is ordered towards the promise of heavenly happiness. This chapter shows some of the resources Augustine offers contemporary discussions of aesthetics by arguing that the way he links beauty and morality accounts for the ethical demands of love elicited by attraction to beauty.

scholarly journals The Enduring Greatness: The Mahāpuruşha Paradigm—An Indian Perspective

2021 ◽  
pp. 002216782110008
Author(s):  
Maharaj K. Raina
Keyword(s):  
Moral Responsibility ◽  
Human Nature ◽  
Human Life ◽  
Human Spirit ◽  
Positive Direction ◽  
Indian Tradition ◽  
Indian Perspective ◽  
Relative Concept ◽  
The Way

Greatness, a relative concept, has been historically approached in different ways. Considering greatness of character as different from greatness of talents, some cultures have conceptualized greatness as an expression of human spirit leading to transcending existing patterns and awakening inner selves to new levels of consciousness, rising above times and circumstances, and to change the direction of human tide. Individuals characterized by such greatness working with higher selves, guided by moral and ethical imperatives, and possessing noble impulses of human nature are considered to be manifesting spiritual greatness. Examining such greatness is the goal of this article. Keeping Indian tradition in focus, this article has studied how greatness has been conceptualized in that particular tradition and the way in which life and times have shaped great individuals called Mahāpuruşha who exhibited extraordinary moral responsibility relentlessly in pursuit of their visions of addressing contemporary major issues and changing the direction of human life. Four Mahāpuruşha, who possessed such enduring greatness and excelled in their thoughts and actions to give a new positive direction to human life, have been profiled in this article. Suggestions have also been made for studies on moral and spiritual excellence to help realize our true human path and purpose.

scholarly journals Does the Arc of Science Bend Towards Impact? Four Decades of Empirical Research Published in JADD Since the DSM-III

2021 ◽  
Author(s):  
Peter Doehring
Keyword(s):  
Empirical Research ◽  
Research Funding ◽  
Basic Research ◽  
Intervention Research ◽  
Community Based ◽  
Community Impact ◽  
Population Impact ◽  
Community Based Programs ◽  
Over 40 Years ◽  
Over Time

AbstractThe present study explored the shift from understanding to intervention to population impact in the empirical research published in this journal at five points of time over 40 years since the release of DSM-III. Two-thirds of the more than 600 original studies identified involved basic research, a pattern that is consistent with previous analyses of research funding allocations and that did not change over time. One of every eight studies involved intervention research, which occurred in community-based programs only about one-quarter of the time. These gaps in intervention research and community impact did not improve over time. The findings underscore the need to broaden the training and experience of researchers, and to re-consider priorities for research funding and publication.

scholarly journals Osteosarcoma Pathogenesis Leads the Way to New Target Treatments

2021 ◽  
Vol 22 (2) ◽  
pp. 813
Author(s):  
Isabel Fernandes ◽  
Cecília Melo-Alvim ◽  
Raquel Lopes-Brás ◽  
Miguel Esperança-Martins ◽  
Luís Costa
Keyword(s):  
Clinical Trials ◽  
Phase I ◽  
Poor Prognosis ◽  
Therapeutic Targets ◽  
Rare Condition ◽  
Basic Research ◽  
Metastatic Setting ◽  
Phase I And Ii ◽  
The Way

Osteosarcoma (OS) is a rare condition with very poor prognosis in a metastatic setting. Basic research has enabled a better understanding of OS pathogenesis and the discovery of new potential therapeutic targets. Phase I and II clinical trials are already ongoing, with some promising results for these patients. This article reviews OS pathogenesis and new potential therapeutic targets.

Can animals sing? On birdsong, music and meaning

2013 ◽  
Vol 52 (2) ◽  
pp. 272-286 ◽  
Author(s):  
Hektor KT Yan
Keyword(s):  
Human Life ◽  
Human Beings ◽  
A Value ◽  
Music And Meaning ◽  
To Come ◽  
Factual Issue ◽  
The Way

This article deals with conceptual questions regarding claims to the effect that humans and animals share artistic abilities such as the possession of music. Recent works focusing on animals, from such as Hollis Taylor and Dominique Lestel, are discussed. The attribution of artistic traits in human and animal contexts is examined by highlighting the importance of issues relating to categorization and evaluation in cross-species studies. An analogy between the denial of major attributes to animals and a form of racism is drawn in order to show how questions pertaining to meaning can impact on our understanding of animal abilities. One of the major theses presented is that the question of whether animals possess music cannot be answered by a methodology that is uninformed by the way concepts such as music or art function in the context of human life: the ascription of music to humans or non-humans is a value-laden act rather than a factual issue regarding how to represent an entity. In order to see how humans and animals share a life in common, it is necessary to come to the reflective realization that how human beings understand themselves can impact on their perception and experience of human and non-human animals.

Is God Really in History?

1979 ◽  
Vol 15 (3) ◽  
pp. 379-390
Author(s):  
Frederick Sontag
Keyword(s):  
Nineteenth Century ◽  
Human Life ◽  
History Of ◽  
The Relationship ◽  
As If ◽  
The Way

For some time it seemed as if Christianity itself required us to say that ‘God is in history’. Of course, even to speak of ‘history’ is to reveal a bias for eighteenth- and nineteenth-century forms of thought. But the justification for talking about the Christian God in this way is the doctrine of the incarnation. The centre of the Christian claim is that Jesus is God's representation in history, although we need not go all the way to a full trinitarian interpretation of the relationship between God and Jesus. Thus, the issue is not so much whether God can appear or has appeared within, or entered into, human life as it is a question of what categories we use to represent this. To what degree is God related to the sphere of human events? Whatever our answer, we need periodically to re-examine the way we speak about God to be sure the forms we use have not become misleading.

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