scholarly journals Prevalence and peculiarities of clinical signs of periodontium diseases in patients with chronic pancreatitis

2014 ◽  
Vol 18 (2 (70)) ◽  
Author(s):  
N. V. Chornii
Keyword(s):  
Chronic Pancreatitis ◽  
Periodontal Disease ◽  
Clinical Signs ◽  
Periodontal Status ◽  
High Prevalence

This paper presents the results of a study of periodontal status in patients with chronic pancreatitis. The study established the high prevalence of periodontal disease in individuals with chronic pancreatitis.The disease manifested itself in a form of generalized chronic catarrhal gingivitis and chronic generalized periodontitis of mild and moderate degrees.

scholarly journals Porcine Gammaherpesviruses in Italian Commercial Swine Population: Frequent but Harmless

Pathogens ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 47
Author(s):  
Giovanni Franzo ◽  
Michele Drigo ◽  
Matteo Legnardi ◽  
Laura Grassi ◽  
Maria Luisa Menandro ◽  
...  
Keyword(s):  
Real Time ◽  
Real Time Pcr ◽  
Clinical Signs ◽  
Northern Italy ◽  
Porcine Circovirus ◽  
Swine Industry ◽  
Positive Interaction ◽  
High Prevalence ◽  
Swine Population ◽  
Clinical Conditions

Differently from alpha- and betaherpesviruses affecting swine, interest in the recently discovered Suid gammaherpesvirus 3, Suid gammaherpesvirus 4, and Suid gammaherpesvirus 5, also known as porcine lymphotropic herpesviruses (PLHV-1, PLHV-2, and PLHV-3), has largely focused on their role as potential zoonotic agents in cases of xenotransplantation. However, their role as primary pathogens of swine or as co-factors for other lymphotropic infections has essentially been neglected. The present study aims at filling this gap, evaluating the association between PLHVs infection and different clinical conditions and/or porcine circovirus (PCV) co-infection. One hundred seventy-six samples were obtained from different animals located in a high-density pig area of Northern Italy in the period 2017–2020. The presence of PLHVs and PCVs was tested and quantified by specific real-time PCR: PLHVs were widespread among pigs (PLHV-1, PLHV-2, and PLHV-3 prevalence was 28.97%, 10.79%, and 4.54%, respectively) and detected in all considered tissues and clinical conditions. Frequent co-infections were also observed among PLHVs and with PCVs, although a significant association was not detected with the exception of a positive interaction between PLHV-1 and PLHV-3, and a negative one between PLHV-2 and PCV-2. Significantly, no association between PLHVs, alone or in co-infection, emerged with any of the considered clinical signs, their frequency being comparable between healthy and diseased animals. Based on these pieces of evidence and despite their high prevalence, PLHVs’ relevance for the swine industry appears negligible, either as primary pathogens or as predisposing factors for circovirus-induced diseases.

scholarly journals Swine Inflammation and Necrosis Syndrome (SINS)

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1670
Author(s):  
Gerald Reiner ◽  
Josef Kuehling ◽  
Frederik Loewenstein ◽  
Mirjam Lechner ◽  
Sabrina Becker
Keyword(s):  
Scientific Evidence ◽  
Age Groups ◽  
Clinical Signs ◽  
Well Being ◽  
Defence Mechanisms ◽  
Newborn Piglets ◽  
High Prevalence ◽  
Histopathological Studies ◽  
Molecular Patterns ◽  
Tail Damage

Tail biting is a prevalent and undesirable behaviour in pigs and a major source of significant reduction in well-being. However, focusing on biting considers only one part of the solution, because tail damage can be found with a high prevalence without any action by other pigs. The lesions are not limited to the tail but can also be found in the ears, heels, soles, claw coronary bands, teats, navel, vulva, and face. Environmental improvement alone often fails to overcome the problem. This review addresses a new inflammation and necrosis syndrome in swine (SINS). It shows the clinical signs and the frequencies of occurrence in different age groups. It compiles scientific evidence from clinical and histopathological studies in newborn piglets that argue for a primary endogenous aetiology of the disease. Bringing together the findings of a broad body of research, the possible mechanisms leading to the disease are identified and then discussed. This part will especially focus on microbe-associated molecular patterns in the circulation and their role in activating defence mechanisms and inflammation. Finally, the methods are identified to ameliorate the problem by optimizing husbandry and selecting a suitable breeding stock.

scholarly journals Bird Lice (Mallophaga, Philopteridae, Menoponidae) of Domestic Pigeons on Specialized Pigeon Breeding Farms in Poltava

2017 ◽  
Vol 51 (6) ◽  
pp. 487-492 ◽  
Author(s):  
I. O. Kolomak ◽  
O. V. Kruchynenko
Keyword(s):  
Species Composition ◽  
Clinical Signs ◽  
Considerable Effect ◽  
Infection Prevalence ◽  
Host Body ◽  
Closed Type ◽  
High Prevalence ◽  
Breeding Farms ◽  
Domestic Pigeons ◽  
Pigeon Breeding

Abstract The species composition of pigeon lice parasitic on pigeons of ornamental breeds on the specialized closed-type farm (Poltava) was studied. Five species of these ectoparasites were registered: Columbicola columbae Linnaeus, 1758, Campanulotes compar Burmeister, 1838, (Philopteridae, Ischnocera), Bonomiella columbae Emerson, 1957, Hohorstiella lata Piaget, 1880 and Neocolpocephalus turbinatum (Denny, 1842) (Menoponidae, Amblycera). For each species, the data on infection prevalence, intensity and abundance were obtained. High prevalence of infection was registered for all pigeon lice species, while the intensity and, especially, the abundance were considerably different. C. columbae turned out to be the most abundant. B. columbae was rather common. The peculiarities of pigeon lice species localization on the host body were investigated. During the intensive infection of pigeons with lice, the complex of clinical signs is manifested, which testifies about considerable effect of these parasites on the host. The highest pathogenicity is characteristic for H. lata, which usually feeds on blood and lymph.

scholarly journals Clinical signs of trachoma are prevalent among Solomon Islanders who have no persistent markers of prior infection with Chlamydia trachomatis

2018 ◽  
Vol 3 ◽  
pp. 14
Author(s):  
Robert Butcher ◽  
Oliver Sokana ◽  
Kelvin Jack ◽  
Leslie Sui ◽  
Charles Russell ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Sexual Debut ◽  
Solomon Islands ◽  
Clinical Signs ◽  
World Health ◽  
Direct Result ◽  
Policy Makers ◽  
The Public ◽  
High Prevalence ◽  
Health Organization

Background: The low population-prevalence of trachomatous trichiasis and high prevalence of trachomatous inflammation–follicular (TF) provide contradictory estimates of the magnitude of the public health threat from trachoma in the Solomon Islands. Improved characterisation of the biology of trachoma in the region may support policy makers as they decide what interventions are required. Here, age-specific profiles of anti-Pgp3 antibodies and conjunctival scarring were examined to determine whether there is evidence of ongoing transmission and pathology from ocular Chlamydia trachomatis (Ct) infection. Methods: A total of 1511 individuals aged ≥1 year were enrolled from randomly selected households in 13 villages in which >10% of children aged 1–9 years had TF prior to a single round of azithromycin mass drug administration undertaken six months previously. Blood was collected to be screened for antibodies to the Ct antigen Pgp3. Tarsal conjunctival photographs were collected for analysis of scarring severity. Results: Anti-Pgp3 seropositivity was 18% in 1–9 year olds, sharply increasing around the age of sexual debut to reach 69% in those over 25 years. Anti-Pgp3 seropositivity did not increase significantly between the ages of 1–9 years and was not associated with TF (p=0.581) or scarring in children (p=0.472). Conjunctival scars were visible in 13.1% of photographs. Mild (p<0.0001) but not severe (p=0.149) scars increased in prevalence with age. Conclusions: Neither conjunctival scars nor lymphoid follicles were associated with antibodies to Ct, suggesting that they are unlikely to be a direct result of ocular Ct infection. Clinical signs of trachoma were prevalent in this population but were not indicative of the underlying rates of Ct infection. The current World Health Organization guidelines for trachoma elimination indicated that this population should receive intervention with mass distribution of antibiotics, but the data presented here suggest that this may not have been appropriate.

scholarly journals Periodontal clinical features of bronchial asthma patient using inhalation drugs

2021 ◽  
Vol 33 (3) ◽  
pp. 217
Author(s):  
Maria Efrinta Ginting ◽  
Rosiliwati Wihardja ◽  
Dyah Nindita Carolina
Keyword(s):  
Periodontal Disease ◽  
Clinical Features ◽  
Bronchial Asthma ◽  
Periodontal Pocket ◽  
Periodontal Status ◽  
Asthmatic Patients ◽  
Gingival Bleeding ◽  
Periodontal Index ◽  
Asthma Patients ◽  
One Year

Introduction: Bronchial asthma patients use inhalation drugs as therapy to achieve a controlled asthma state. Inhaled corticosteroids and β2 agonists are the medication that is being used in this case. Prolonged use of inhalation drugs will affect the health of periodontal tissue. The effect of these drugs can reduce the periodontal defense mechanism and increase the risk of periodontal disease. This study aims to determine the periodontal clinical features of bronchial asthma patients using inhalation drugs. Method: This research was a descriptive study. The sample of the study were 22 females and 8 males bronchial asthma patients at the Community Lung Health Center of Bandung (Balai Besar Kesehatan Paru Masyarakat Bandung/BBKPM Bandung) who had been using inhalation drugs for at least one year. The periodontal clinical feature was assessed by employing a Community Periodontal Index (CPI) modified with probing the gingival sulcus to assess the presence of gingival bleeding, periodontal pocket, and loss of clinical attachment where then a periodontal status was obtained. The periodontal status data were then processed using the periodontitis case definitions from the Centers for Disease Control and Prevention/American Academy of Periodontology (CDC/AAP) to determine periodontal disease in asthmatics patients. Results: Clinical features of gingival bleeding were found in 26 asthmatic patients (86.7%), periodontal pockets in 18 asthmatic patients (60%), and loss of clinical attachment in 27 asthmatic patients (90%). Based on the CDC/AAP case definition, 23 asthmatic patients (76.7%) had periodontitis. Bronchial asthma patients who used inhalation drugs had a risk of periodontitis.Conclusion: Bronchial asthma patients who used inhalation drugs for at least one year had gingival bleeding and loss of clinical attachment and periodontal pocket.

scholarly journals NLRP3 Inflammasome Expression in Gingival Crevicular Fluid of Patients with Periodontitis and Chronic Hepatitis C

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Petra Surlin ◽  
Luminita Lazar ◽  
Cerasella Sincar ◽  
Dorin Nicolae Gheorghe ◽  
Dora Maria Popescu ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Periodontal Disease ◽  
Chronic Hepatitis C ◽  
Inflammatory Reaction ◽  
Nlrp3 Inflammasome ◽  
Gingival Crevicular Fluid ◽  
Periodontal Status ◽  
Local Inflammatory Reaction ◽  
Crevicular Fluid

The study is aimed at assessing the impact that periodontal disease and chronic hepatitis C could have on gingival crevicular fluid levels of the NLRP3 inflammasome, caspase-1 (CASP-1), and interleukin-18 (IL-18) and at evaluating whether the increased local inflammatory reaction with clinical periodontal consequences is correlated to their upregulation. Patients were divided into four groups, according to their periodontal status and previously diagnosed hepatitis C, as follows: (i) CHC group, chronic hepatitis C patients; (ii) P group, periodontal disease patients, systemically healthy; (iii) CHC + P group, patients suffering from both conditions; and (iv) H group, systemically and periodontally healthy controls. Gingival crevicular samples were collected for quantitative analysis of the NLRP3 inflammasome, CASP-1, and IL-18. CHC + P patients expressed the worse periodontal status and the highest NLRP3, CASP-1, and IL-18 levels, the difference being statistically significant ( p < 0.05 ). The P group patients also expressed significantly more elevated NLRP3, CASP-1, and IL-18 levels, as compared to nonperiodontal patients (CHC and H groups). Chronic hepatitis C and periodontal disease could have a significant influence on the upregulation of NLRP3 inflammasome and its components, possibly contributing to an increased local inflammatory reaction and clinical periodontal consequences.

First report of wild boar susceptibility to Porcine circovirus type 3: High prevalence in the Colli Euganei Regional Park (Italy) in the absence of clinical signs

2018 ◽  
Vol 65 (4) ◽  
pp. 957-962 ◽  
Author(s):  
Giovanni Franzo ◽  
Claudia Maria Tucciarone ◽  
Michele Drigo ◽  
Mattia Cecchinato ◽  
Marco Martini ◽  
...  
Keyword(s):  
Wild Boar ◽  
Clinical Signs ◽  
Porcine Circovirus Type ◽  
Porcine Circovirus ◽  
First Report ◽  
High Prevalence ◽  
Type 3

α1-Antitrypsin Phenotypes in Patients with Anti-Neutrophil Cytoplasmic Antibody-Positive Vasculitis

1994 ◽  
Vol 87 (6) ◽  
pp. 693-695 ◽  
Author(s):  
Karl Lhotta ◽  
Wolfgang Vogel ◽  
Thomas Meisl ◽  
Martina Buxbaum ◽  
Ulrich Neyer ◽  
...  
Keyword(s):  
Systemic Vasculitis ◽  
Clinical Signs ◽  
Rapidly Progressive Glomerulonephritis ◽  
Control Group ◽  
Severe Deficiency ◽  
High Prevalence ◽  
Antitrypsin Deficiency ◽  
Hardy Weinberg Equilibrium ◽  
Microscopic Polyarteritis ◽  
A Minor

1. The genetic background of anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis remains largely unknown. Recently a very high prevalence of medium and severe deficiency of α1-antitrypsin was described in a small group of patients with Wegener's granulomatosis and c-ANCA. c-ANCAs are autoantibodies against proteinase 3, and α1-antitrypsin is the main inhibitor of this enzyme. 2. α1-Antitrypsin phenotypic polymorphism was determined by isoelectric focusing in 32 patients with c-ANCA-associated systemic vasculitis. Twenty-nine patients had Wegener's disease, two had microscopic polyarteritis and one suffered from idiopathic rapidly progressive glomerulonephritis. 3. Two patients were homozygous PiZZ and three were heterozygous PiMZ. These phenotype frequencies differed significantly from expected values, assuming Hardy-Weinberg equilibrium (P < 0.01). Compared with a control group of 868 healthy blood donors, these results meant a significant increase in the PiZ allele (0.0138 versus 0.1094, P< 0.001). 4. Furthermore, the serum of 47 patients with severe α1-antitrypsin deficiency (PiZZ) was tested for the presence of ANCA. All sera were negative for c-ANCA and p-ANCA. None of the patients showed clinical signs of systemic vasculitis. 5. In conclusion, these data indicate that α1-antitrypsin deficiency, despite being significantly more common in patients with c-ANCA-associated systemic vasculitis, is only a minor genetic risk factor for the development of this disease.

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