scholarly journals COST AND EFFECTIVENESS OF ATYPICAL-ATYPICAL ANTIPSYCHOTIC COMBINATIONS AND ATYPICAL-TYPICAL ANTIPSYCHOTIC COMBINATIONS IN PATIENTS OF PSYCHOTIC DISORDERS IN INSTALLATION OF EMERGENCY IN GRHASIA MENTAL HOSPITAL, YOGYAKARTA

2021 ◽  
Vol 18 (2) ◽  
pp. 112-117
Author(s):  
Arya Dibyo Adisaputra ◽  
Endang Darmawan ◽  
Arum Siwinarni
Keyword(s):  
Atypical Antipsychotic ◽  
Average Cost ◽  
Psychotic Disorders ◽  
Combination Group ◽  
Typical Antipsychotic ◽  
Total Cost ◽  
Time Period ◽  
The Difference ◽  
The Government ◽  
The Cost

Psychotic disorders create a burden on the government, family, and society because of decreasing patient productivity. The use of atypical-atypical and atypical-typical antipsychotic combinations is one of the most commonly used combinations for patients with psychotic disorders. The study was conducted to determine the average total cost and effectiveness of the therapy measured by the difference in PANSS-EC pre-post scores during intensive care. The study was conducted prospectively to analyse the total cost and effectiveness of the therapy using combinations of antipsychotics in psychotic disorders patients. The measured costs include the cost of nursing classes, laboratory, medical treatment, doctor's visit, and antipsychotic. The effectiveness is measured by the difference in PANSS-EC pre-post scores. As many as 32 treated patients with psychotic disorders met the inclusion criteria. The average cost of atypical-typical antipsychotic combination group (Rp1,184,043) was higher than atypical atypical antipsychotic combination group (Rp1,115,829). The effectiveness of the therapy was represented by the value of the difference between the PANSS-EC pre and post scores, which in this research yielded a mean of 7,125 for atypical-atypical antipsychotic combinations and 8,375 for atypical-typical antipsychotic combinations. In conclusion, there is a difference in the total average cost and effectiveness of the therapy. There is a difference between PANSS-EC pre and post scores during the time period from intensive room to quiet room in atypical-typical antipsychotic combinations compared with atypical-atypical antipsychotic combinations.

scholarly journals Review of the efficacy of placebo in comparative clinical trials between typical and atypical antipsychotics

2009 ◽  
Vol 31 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Irismar Reis de Oliveira ◽  
Paulo Menezes Nunes ◽  
Domingos Macedo Coutinho ◽  
Eduardo Pondé de Sena
Keyword(s):  
Clinical Trials ◽  
Atypical Antipsychotic ◽  
Atypical Antipsychotics ◽  
Rating Scale ◽  
Study Drug ◽  
Typical Antipsychotic ◽  
The Difference ◽  
Psychiatric Rating Scale ◽  
Efficacy Parameters ◽  
Typical Antipsychotics

OBJECTIVE: To review the efficacy of placebo in comparison with atypical and typical antipsychotics for the treatment of schizophrenia and schizoaffective disorder and to evaluate the pertinence of using placebo in clinical trials with antipsychotics. METHOD: Trials in which the atypical antipsychotics were compared with typical antipsychotics and placebo were included. A search was conducted using the terms "amisulpride", "aripiprazole", "clozapine", "olanzapine", "quetiapine", "risperidone", "sertindole", "ziprasidone" and "zotepine". Main efficacy parameters were calculated using the proportion of "events" (defined as a deterioration or lack of improvement by at least 20% in Positive and Negative Syndrome Scale or Brief Psychiatric Rating Scale) and the pooled relative risk with random effects, with their respective 95% confidence intervals. We also calculated the necessary sample sizes in studies in which the study drug is compared to a typical antipsychotic or placebo. RESULTS: The pooled efficacy rates observed were 40.8%, 34.9% and 21.3% for the atypical antipsychotics, typical antipsychotics and placebo, respectively. One hundred and sixty six patients would have to be included when a new drug is compared with placebo if calculation is based on a difference of 20% found between the atypical antipsychotic and placebo and 2,054 if the difference sought were that found between the atypical antipsychotic and the typical antipsychotic, i.e. 6%. The estimated therapeutic failures would be 115 of the 166 patients when the study drug is compared with placebo, and 1,274 failures in the 2,054 patients when the study drug is compared to the typical antipsychotic. CONCLUSIONS: Placebo controlled studies may reduce the number of individuals exposed to the harmful effects of ineffective drugs.

Cost-Consequence Analysis of Single-Dose Dalbavancin Versus Standard of Care for the Treatment of Acute Bacterial Skin and Skin Structure Infections in a Multisite Healthcare System

2020 ◽  
Author(s):  
Julia Gonzalez ◽  
Diana Carolina Andrade ◽  
JianLi Niu
Keyword(s):  
Healthcare System ◽  
Treatment Success ◽  
Standard Of Care ◽  
Cost Of Care ◽  
Secondary Outcome ◽  
Total Cost ◽  
Skin Structure ◽  
Cost Consequence ◽  
The Difference ◽  
The Cost

Abstract Background Acute bacterial skin and skin structure infections (ABSSSIs) are common infectious diseases that cause a significant economic burden on the healthcare system. This study aimed to compare the cost-effectiveness of dalbavancin vs standard of care (SoC) in the treatment of ABSSSI in a community-based healthcare system. Methods This was a retrospective study of adult patients with ABSSSI treated with dalbavancin or SoC during a 27-month period. Patients were matched based on age and body mass index. The primary outcome was average net cost of care to the healthcare system per patient, calculated as the difference between reimbursement payments and the total cost to provide care to the patient. The secondary outcome was proportion of cases successfully treated, defined as no ABSSSI-related readmission within 30 days after the initiation of treatment. Results Of the 418 matched patients, 209 received SoC and 209 received dalbavancin. The average total cost of care per patient was greater with dalbavancin vs SoC ($4770 vs $2709, P < .0001). The average reimbursement per patient was $3084 with dalbavancin vs $2633 SoC (P = .527). The net cost, calculated as revenue minus total cost, was $1685 with dalbavancin vs $75 with SoC (P = .013). The overall treatment success rate was 74% with dalbavancin vs 85% with SoC (P = .004). Conclusions Dalbavancin was more costly than SoC for the treatment of ABSSSI, with a higher 30-day readmission rate. Dalbavancin does not offer an economic or efficacy advantage.

scholarly journals ANALISIS KETERLAMBATAN PROYEK SERTA DAMPAKNYA TERHADAP BIAYA DAN WAKTU PELAKSANAAN PROYEK

2019 ◽  
Vol 5 (1) ◽  
pp. 13-19
Author(s):  
Fitri Nur Kharina ◽  
Kusno Adi Sambowo
Keyword(s):  
Construction Projects ◽  
Construction Project ◽  
Project Performance ◽  
Project Work ◽  
Earned Value ◽  
Time Period ◽  
Review Period ◽  
The Difference ◽  
The Cost ◽  
The Impact

Construction projects in all regions continues to be developed for the creation of facilities that can be utilized by the community. One of them is the construction of apartments which are now being intensively carried out to meet residential needs for the community. Making a construction project plan always refers to estimates that exist at the time development plan is made, therefore problems can arise if there is a discrepancy between the plans that have been made and the actual reality. So the impact that often occurs is the delay in the time of project implementation which can also be accompanied by an increase in the cost of implementing the project. In the construction project of Cinere Terrace Suites Apartemen & Citywalk, Jakarta there was a delay resulting in a late payment of monthly bill progress by the owner. Based on the above reasons, this research was conducted to find out how the project performance was seen from the cost and time period of the review period. how is the estimated cost and time to complete the overall project work. The method used in the analysis of this study is the Earned Value Method. Based on the results of the analysis carried out for 29 weeks the project performance on schedule has been delayed and cost shows a positive value. For the estimated completion time of the project there is an increase in time whose duration increases from the planned 98 weeks or 685 days to 109,624 weeks or 768 days. While the estimated cost of completing the project from the results of the analysis obtained a value of Rp. 270,147,448,569.16 smaller than the planned cost of Rp. 315,272,727,272.73. With the difference VAC of Rp. 45,125,278,703.57 this shows that there are benefits obtained by the contractor.

scholarly journals Deprivation of Liberty Safeguards in England: implementation costs

2011 ◽  
Vol 199 (3) ◽  
pp. 232-238 ◽  
Author(s):  
Ajit Shah ◽  
Mark Pennington ◽  
Chris Heginbotham ◽  
Cam Donaldson
Keyword(s):  
Average Cost ◽  
Mental Capacity ◽  
Resource Utilisation ◽  
First Year ◽  
Mental Capacity Act 2005 ◽  
Implementation Costs ◽  
The Government ◽  
Mental Capacity Act ◽  
The Cost ◽  
Utilisation Data

BackgroundThe Deprivation of Liberty Safeguards (DoLS), introduced into the Mental Capacity Act 2005, were fully implemented on 1 April 2009 in England and Wales. The government estimated 20 000 assessments for DoLS at a cost of £600 per assessment.AimsTo estimate the costs likely to be incurred with the implementation of DoLS in England.MethodThe cost of conducting a single DoLS assessment was estimated using resource-utilisation data ascertained from 37 professionals, secretarial staff and independent mental capacity advocates involved with DoLS assessments in six diverse local DoLS offices.ResultsThe estimated average cost of a single DoLS assessment was £1277.ConclusionsThe estimated average cost of a single DoLS assessment was significantly higher than the £600 estimated by the government. However, the allocated budget, based on 20 000 estimated DoLS assessments in the first year of its implementation, is likely to be adequate because a significantly lower number of assessments (only 5200) were conducted in the first 9 months after its implementation.

scholarly journals ANALISIS USAHA HOME INDUSTRI KERUPUK RAMBAK

2017 ◽  
Vol 11 (1) ◽  
pp. 35-45
Author(s):  
Syarifah Aini ◽  
Erlin Widya Fatmawati
Keyword(s):  
Variable Cost ◽  
Fixed Cost ◽  
Business Activity ◽  
Total Cost ◽  
Total Variable Cost ◽  
Cost Of Production ◽  
The Government ◽  
The Cost ◽  
Breakeven Point

The purpose of this research is to know the amount of cost, acceptance, profit, profitability, and R / C Ratio from home industry crackers rambak in Sembon Village Satreyan District Kanigoro Blitar District. The result of this research shows that the total variable cost at rambak cracker agroindustry center is equal to Total variable cost Rp 1,139,783, - per day, total fixed cost Rp 4,953, - per day. So the total total cost of production is Rp 1,144,076, - per month. The breakeven point or BEP unit is 3 units. BEP Rp for RP 16,017, -. BEP revenue of Rp 16,017, - per day. Received revenue of Rp 1.650.000, - so the profit earned by employers is amounted to Rp 505,924, -. While the profitability of business is 44% which means this business is profitable. Home industry that run during this efficiency has been shown with R / C ratio of more than 1 that is equal to 1.44. Based on the criteria used, this business has been efficient because the efficiency value of more than 1. This means that every Rp 1.00 issued by the entrepreneur at the beginning of the business activities will get 1.44 times revenue from the cost incurred at the end of the business activity. This can be interpreted that home industry crackers rambak said Eligible to run. From this research it is suggested that entrepreneurs do creations by adding a sense of the product, so that the quality of the product can be increased and not less competitive with similar entrepreneurs from other regions. For the government, the Government of Blitar Regency through the Department of Industry and Trade and other related agencies should try to help develop the business crackers rambak by providing low-interest capital loans to entrepreneurs agro-industry crackers rambak.

scholarly journals ANALISIS PERBANDINGAN EFISIENSI TENAGA KERJA SEMI MEKANIS DAN MANUAL PADA SESI POTONG BUAH (Studi kasus di Puhus 2 Estate PT Dharma Agrotama Nusantara di Desa Muara Wahau) (The Comparison Analysis of Efficiency of Semi Mechanical and Manual Labors on Fruit Cutting Session (Case study at Puhus 2 Estate PT. Dharma Agrotama Nusantara in Muara Wahau Village))

2018 ◽  
Vol 1 (1) ◽  
pp. 39
Author(s):  
PUTERI APRILANI ◽  
TETTY WIJAYANTI
Keyword(s):  
Palm Oil ◽  
Average Cost ◽  
Production Factor ◽  
Manual Labor ◽  
Comparison Analysis ◽  
The Difference ◽  
Fresh Fruit Bunches ◽  
The Cost ◽  
The Village

The purposes of this research were to know the difference between semi mechanical and manual on harvesting of palm oil and to know the efficiency of semi mechanical and manual labor on fruit cutting session of Fresh Fruit Bunches (TBS) of palm oil in Puhus 2 Estate of PT. Dharma Agrotama Nusantara (DAN) in the Village of Muara Wahau. This research was held for three months, start from March to May 2017 in Puhus 2 Estate PT. DAN in  Muara Wahau Village, Muara Wahau Subdistrict, East Kutai District. The result showed that the difference of utilization of semi mechanical and manual labor is not just on the use of machine or tools but there is also difference on the basic of the harvesters and cost. In semi mechanical labor, the average cost in four months was IDR89,057 ton-1 and 2,628.41 ton of production, while the cost of manual labor was IDR108,367 ton-1 with 1,677.03 ton of production. The production factor utilization of semi mechanical labor is more efficien compare to utilization of manual labor in the fruit cutting session of PT. DAN in Muara Wahau Village, Muara Wahau District, East Kutai District.

scholarly journals Financial cost of elective day of surgery cancellations

2018 ◽  
Vol 7 (5) ◽  
pp. 30
Author(s):  
Elina Turunen ◽  
Merja Miettinen ◽  
Leena Setälä ◽  
Katri Vehviläinen-Julkunen
Keyword(s):  
Healthcare Services ◽  
University Hospital ◽  
Financial Loss ◽  
Financial Cost ◽  
Total Cost ◽  
Operative Care ◽  
Time Period ◽  
Cancellation Rate ◽  
The Cost

Operative care is one of the major areas of healthcare services as over 310 million surgeries are conducted yearly. Surgery cancellations is a widely used indicator when evaluating the quality of preoperative care. Cancellations cause financial lost for organizations, however there is only limited research about the costs. The aim of this study was to evaluate the cost of elective day of surgery (DOS) cancellations in 13 operative specialties at a university hospital in Finland between September 1, 2015 and May 31, 2016 after a structured preoperative protocol was implemented to practice and a cancellation rate of 4.7% was recognized. Procedure prices conducted the data for the research and were collected from the hospital’s invoicing system. Financial loss and savings of cancellations were calculated from the total cost of procedures. As a result the total cost of DOS cancellations during the nine-month time period was 953,374.27 euros and mean loss of a single cancelled operation was 2,459.91 euros. The total of material savings for the hospital were 106,917.33 euros. As a conclusion, DOS cancellations cause unnecessary wastage, and financial aspects should be followed and evaluated systematically by setting goals and providing continuing developments.

scholarly journals Research on Behavior Incentives of Prefabricated Building Component Manufacturers

Information ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 284
Author(s):  
Pinbo Yao ◽  
Hongda Liu
Keyword(s):  
Incremental Cost ◽  
Evolutionary Game ◽  
Development Stage ◽  
Mature Stage ◽  
Positive Externalities ◽  
Initial Stage ◽  
Material Component ◽  
The Difference ◽  
The Government ◽  
The Cost

Based on the positive externalities of prefabricated buildings, this paper constructs an evolutionary game model between the government and material component vendors and analyzes the changes in the behavior of the government and component vendors in different stages of the advancement of prefabricated buildings. Based on data modeling and equation prediction analysis, it can be found that the expansion of the incremental cost of construction at the initial stage inhibits the enthusiasm of the government. Thus, the government’s incentive behavior effectively affects the behavior of component vendors, and fiscal taxation and punishment policies will promote component vendors to provide prefabricated components. In the development stage, the government’s fiscal policy influence that weakens and affects component vendors’ behavior mainly comes from the incremental costs and benefits of components. Additionally, the difference between the builder’s incremental cost and the sales revenue narrowed. At this time, the behavior prediction of both parties tends to be steady. In the mature stage, prefabricated buildings will mainly rely on market forces, and the government can gradually withdraw from the market. The cost variable tends to be lower, and it can be predicted that component vendors tend to supply components, while the government tends to restrict policies.

Media Capture and Bias in the Market for News

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Abhra Roy
Keyword(s):  
Media Bias ◽  
The State ◽  
Actual State ◽  
Noisy Signal ◽  
Free Press ◽  
State Of The Economy ◽  
The Media ◽  
The Difference ◽  
The Government ◽  
The Cost

Abstract We analyze a model of media bias under government capture and a free press. The government wants citizens to invest in a project. Citizens gain from investing only if the state of the economy is good. The state is unobserved. The media firm receives a noisy signal about the actual state and makes a report about whether or not the state of the economy is good. Citizens read the report and decide whether or not to invest. In this context, we show that media bias under government capture may be smaller (greater) than that under free press if the cost of investment is sufficiently high (low) provided that the signal noise is below a certain threshold. Finally, we show that the difference between the bias under government capture and free press diverges (converges) when the cost of investment is sufficiently high (low) in response to a reduction in noise.

scholarly journals The difference between the magnetic diurnal variations on ordinary and quiet days at Kew Observatory

1915 ◽  
Vol 91 (630) ◽  
pp. 370-381
Keyword(s):  
Magnetic Force ◽  
Mean Value ◽  
Magnetic Elements ◽  
New Material ◽  
The Mean ◽  
The Difference ◽  
The Government ◽  
Government Grant ◽  
The Cost ◽  
Large Disturbance

§1. While investigating the nature of the diurnal inequality of the magnetic elements at Kew Observatory, I have discovered a somewhat remarkable relationship between the inequalities derived respectively from quiet days and from ordinary days ( i. e. all days expert those of large disturbance). The period whose records were employed consisted of the 11 years 1890 to 1900. During that period five days were selected for each month by the Astronomer Royal as typical of quiet conditions. An analysis of the diurnal inequalities at Kew on these days was given in an earlier paper. Use is also made of the diurnal inequalities derived from 209 disturbed days, being the days of principal disturbance from 1890 to 1900. The new material employed consists of diurnal inequalities based on all the days of the 11 years, excluding the 209 highly disturbed days but including the quiet days. The cost of measuring the curves was defrayed by a grand from the Government Grant Committee. The diurnal variation in the horizontal components of magnetic force is often advantageously studied by considering the vector which represents the force to whose action the departure from the mean value for the day may be ascribed.

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