scholarly journals INDEKS ATEROGENIK PLASMA DI PENYAKIT DIABETES MELITUS TIPE 2 (Atherogenic Index of Plasma in Type 2 Diabetes Mellitus)

2018 ◽  
Vol 22 (1) ◽  
pp. 82
Author(s):  
Amarensi M Betaubun ◽  
Uleng Bahrun ◽  
Ruland Pakasi
Keyword(s):  
Glucose Level ◽  
Fasting Glucose ◽  
Colorimetric Method ◽  
Cross Sectional Study ◽  
Atherogenic Index ◽  
Atherogenic Dyslipidemia ◽  
Fasting Glucose Level ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma

Atherogenic Index of Plasma (AIP) as a new marker of atherogenicity and directly related to the risk of atherosclerosis, is a simpleand inexpensive method to assess the severity of atherogenic dyslipidemia. 97% of adult patients with type 2 DM (T2DM) will havedyslipidemia including increased levels of TG, low HDL-C levels whereas LDL cholesterol levels had no effect. To determine the atherogenicindex of plasma in controlled and uncontrolled T2DM. A Cross-sectional study was conducted on 72 controlled T2DM samples and 112uncontrolled T2DM samples from Clinic of Endocrine and Methabolic dr Wahidin Sudirohusodo Hospital Makassar, starting from April-May 2013. Fasting glucose level, triglycerides, HDL-C and HbA1c determined using ABX Pentra 400 (colorimetric method). Data thenanalyzed with Mann Withney U test. Most of the samples are male, with the age range from 51-60 years old. Mean AIP is not so differentbetween the two groups (0.51±0.28 and 0.55±0.28 respectively). Fasting glucose level, triglycerides, HDL-C in T2DM uncontrolled werehigher than controlled. The atherogenic index of plasma of controlled T2DM group were 0.93 times lower than uncontrolled T2DM, MannWithney U test showed that there were no significant correlation between both of group (p>0.05). Atherogenic index of plasma cannotbe used to distinguish between controlled and uncontrolled T2DM.

Abstract T P99: Elevated Fasting Glucose as a Potential Predictor for Asymptomatic Cerebral Stenosis: A Cross-Sectional Study in Chinese Adults

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Jing Wang ◽  
Jianwei Wu ◽  
Chunxue Wang ◽  
Shouling Wu ◽  
Xingquan Zhao
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Carotid Stenosis ◽  
Glucose Level ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Cross Sectional Study ◽  
Fasting Glucose Level ◽  
Cross Sectional ◽  
Potential Risk Factors

Purpose: Cerebral Stenosis is known as an important cause of stroke, and elevated fasting glucose level is traditionally supposed as a risk factor for stroke; however, it is doubtful whether elevated fasting glucose is associated with cerebral stenosis, especially with asymptomatic cerebral stenosis . Methods: 5,309 participants with age of 40 years or older, free of stroke, transient ischemic attack, and coronary disease, were enrolled in this study from 2010 to 2011. Information of potential risk factors for cardiovascular disease were collected and cerebral stenosis was assessed by Doppler ultrasound. Participants were classified into four subtypes: non-cerebral steosis (NCS), intracranial artery stenosis (ICAS), extracranial carotid stenosis (ECCS) and combined intracranial and extracranial carotid stenosis (IECS). Fasting blood glucose (FBG) was also stratified into normal fasting glucose (FBG<5.60mmol/L), impaired fasting glucose (IFG) (FBG: 5.60-6.99mmol/L) and diabetes (FBG>6.99mmol/L) groups. The IFG group was further divided into IFG1 and IFG2 at cutpoint of 6.10mmol/L. A multivariate logistic regression was used to examine the association between FBG and cerebral stenosis. Results: FBG levels were significantly higher in ICAS and IECS groups than the other two groups. In multiple regression analysis, IFG2 level was the risk factor for ICAS (OR 1.50, 95%CI 1.10-2.06), and diabetes level was a powerful predictor for ICAS (OR 1.82, 95%CI 1.43-2.31) and IECS (OR 2.22, 95%CI 1.36-3.62). However, the paper finds fasting glucose level was not a risk factors for ECCS. Conclusions: The results suggest that elevated fasting glucose level is associated with asymptomatic cerebral stenosis, especially with ICAS and IECS, which suggesting the importance of fasting glucose control in the prevention of asymptomatic cerebral stenosis.

scholarly journals The relationship between the atherogenic index of plasma and arterial stiffness in essential hypertensive patients from China: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Juan Yin ◽  
Minghui Li ◽  
Lingling Yu ◽  
Feng Hu ◽  
Yu Yu ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Arterial Stiffness ◽  
Linear Regression Analysis ◽  
Cross Sectional Study ◽  
Atherogenic Index ◽  
Chinese Patients ◽  
Multivariate Linear Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma

Abstract Background The atherogenic index of plasma (AIP) always remains in a potential association with arterial stiffness, however, this association has not been fully discovered and needs to be studied in depth in large hypertensive patient populations. The present analysis thus sought to further explore the association that exists between AIP and arterial stiffness in Chinese patients diagnosed with arterial hypertension. Methods This cross-sectional study analyzed 4744 Chinese individuals with essential hypertension. AIP was defined as the base 10 logarithm of the ratio of plasma of triglycerides to high-density lipoprotein cholesterol levels indicated in molar concentrations. Measurement of arterial stiffness was carried out via brachial-ankle pulse wave velocity (baPWV). Results Data were adjusted for potential confounding variables, and multivariate linear regression analysis revealed AIP to be positively correlated with baPWV (β = 1.34, 95% CI: 0.96 to 1.72, P < 0.001). When AIP was instead treated as a categorical variable divided into quartiles, the same relationship was observed (P for trend < 0.001). We additionally found AIP and baPWV had a stronger positive association in individuals with a body mass index (BMI) < 24 kg/m2 (P for interaction < 0.05). Conclusion AIP and arterial stiffness were positively correlated in essential hypertension patients in China, especially in those with a BMI < 24 kg/m2. Clinical trial registration ChiCTR1800017274.

scholarly journals The Relationship Between the Atherogenic Index of Plasma and Arterial Stiffness in Essential Hypertensive Patients from China: A Cross-Sectional Study

2021 ◽  
Author(s):  
Juan Yin ◽  
Minghui Li ◽  
Lingling Yu ◽  
Feng Hu ◽  
Yu Yu ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Arterial Stiffness ◽  
Linear Regression Analysis ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Atherogenic Index ◽  
Multivariate Linear Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma

Abstract Background: The atherogenic index of plasma (AIP) always remains in a potential association with the arterial stiffness, however, in large hypertensive patient populations, this relation is not fully discovered and needs to be studied in depth. The present analysis thus sought to further explore the association that exists between AIP and arterial stiffness in patients diagnosed with arterial hypertension in China.Methods: This cross-sectional study analyzed 4744 Chinese individuals with essential hypertension. AIP was defined as the base 10 logarithm of the ratio of plasma of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-c) levels indicates as in molar concentrations. Measurement of arterial stiffness was carried out via brachial-ankle pulse wave velocity (baPWV).Results: Data were adjusted for potential confounding variables, after which a multivariate linear regression analysis revealed AIP to be positively correlated with baPWV (β = 1.34, 95% CI: 0.96 to 1.72, P < 0.001). When AIP was instead treated as a categorical variable divided into quartiles, this same relationship was observed (P for trend < 0.001). We additionally found AIP and baPWV had a stronger positive association in individuals with a body mass index (BMI) < 24 kg/m2 (P for interaction < 0.05).Conclusion: AIP and arterial stiffness were positively correlated in essential hypertension patients in China, especially in those with a BMI < 24 kg/m2.

scholarly journals Association of impaired fasting glucose and Type 2 Diabetes Mellitus with brain volume changes in Alzheimer’s Disease patients analyzed by MRI: a retrospective study

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e9801
Author(s):  
Weiwei Wang ◽  
Leongtim Wong ◽  
Lin Shi ◽  
Yishan Luo ◽  
Zhanhua Liang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glucose Level ◽  
Brain Volume ◽  
Fasting Glucose ◽  
Fasting Glucose Level ◽  
Volume Changes ◽  
Brain Volumes

Objectives Alzheimer’s disease (AD), impaired fasting glucose (IFG), and Type 2 diabetes mellitus (T2DM) were reported associated with smaller brain volumes. Nevertheless, the association of hyperglycemia with brain volume changes in AD patients remains unclear. To investigate this issue, structural magnetic resonance imaging was used to compare brain volumes among AD patients with different fasting glucose levels. Methods Eighty-five AD patients were divided into three groups based on their fasting glucose level as suggested by the American Diabetes Association: normal fasting glucose group (AD_NFG, n = 45), AD_IFG group (n = 15), and AD_T2DM group (n = 25). Sagittal 3D T1-weighted images were obtained to calculate the brain volume. Brain parenchyma and 33 brain structures were automatically segmented. Each regional volume was analyzed among groups. For regions with statistical significance, partial correlation analysis was used to evaluate their relationships with fasting glucose level, corrected for Mini-Mental State Examination score, age, education level, cholesterol, triglyceride, and blood pressure. Results Compared with the AD_IFG and AD_NFG groups, the volume of pons in AD_T2DM group was significantly smaller. Fasting glucose was negatively correlated with pontine volume. Conclusions T2DM may exacerbate pontine atrophy in AD patients, and fasting glucose level is associated with pontine volume.

Fasting glucose level is associated with nocturnal hypoglycemia in elderly male patients with type 2 diabetes

2013 ◽  
Vol 16 (3) ◽  
pp. 132-136 ◽  
Author(s):  
Fusheng Fang ◽  
Haiying Xiao ◽  
Chunlin Li ◽  
Hui Tian ◽  
Jian Li ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glucose Level ◽  
Fasting Glucose ◽  
Fasting Glucose Level ◽  
Elderly Male ◽  
Nocturnal Hypoglycemia ◽  
Male Patients

scholarly journals Secondhand Smoke Exposure, Diabetes, Elevated Glucose Level Are Risk Factors for Uterine Cervical Cancer: A Cross-Sectional Study From the Korea National Health and Nutrition Examination Survey (2010-2018)

2021 ◽  
Author(s):  
Ji Young Kim ◽  
Dae Woo Lee ◽  
Min Jeong Kim ◽  
Jae Eun Shin ◽  
Yeun Joo Shin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
Glucose Level ◽  
Secondhand Smoke ◽  
Fasting Glucose ◽  
Smoke Exposure ◽  
Secondhand Smoke Exposure ◽  
Work Schedule ◽  
Fasting Glucose Level ◽  
Cross Sectional

Abstract Background: Human papilloma virus infection and tobacco smoking are the major risk factors for cervical cancer. There are limited studies searching other risk factors for cervical cancer and the results are not consistent. This study investigated the relations between cervical cancer and possible risk factors, including secondhand cigarette smoke exposure, diabetes, work schedule. Methods: In this cross-sectional study, 29,557 women completed a cervical cancer questionnaire and were selected using 2010–2018 data from the Korea National Health and Nutrition Examination Survey. Details in secondhand smoke exposure, diabetes, work schedule were assessed from participants’ health interviews and blood test results were used for fasting glucose level and hemoglobin A1c (HbA1c) level.Results: Two hundred sixty-two women (0.89%) in the sample were diagnosed with cervical cancer. Domestic secondhand smoke exposure, diabetes, high fasting glucose level, and high HbA1c significantly increased cervical cancer risk. The respective odd ratios and 95% confidence intervals were: 1.488 (1.002–2.207), 2.369 (1.713–3.274), 1.008 (1.005–1.009), and 1.304 (1.193–1.425). Weekly work hours and work schedule were not significantly related to cervical cancer incidence.Conclusion: Among Korean women, passive exposure to cigarette smoke at home, diabetes, elevated fasting glucose level, and high HbA1c level all increase risk for cervical cancer.

Strong association between serum Vitamin D and Vaspin Levels, AIP, VAI and liver enzymes in NAFLD patients

2020 ◽  
Vol 90 (1-2) ◽  
pp. 59-66 ◽  
Author(s):  
Azimeh Izadi ◽  
Fereshteh Aliasghari ◽  
Bahram Pourghassem Gargari ◽  
Sara Ebrahimi
Keyword(s):  
Vitamin D ◽  
Liver Enzymes ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Atherogenic Index ◽  
Visceral Adiposity Index ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Serum Vitamin D ◽  
Males And Females

Abstract. Some studies indicated poor vitamin D level in NAFLD which is independently correlated with severity of steatosis. Low 25(OH) D3 levels are associated with an impaired lipid profile. Impaired levels and function of vaspin and omentin, which are adipokines, have been demonstrated in NAFLD patients. This study determined the relationship between vitamin D and serum liver enzymes, ultrasound findings, some adipokines, atherogenic index of plasma (AIP) and visceral adiposity index (VAI) in patients with NAFLD in a cross-sectional study. This study was a cross-sectional study in eighty-three NAFLD patients (57 males and 26 females). Plasma levels of omentin-1e-1, vaspin were measured. Anthropometric indices metabolic status was assessed. Visceral adiposity index and atherogenic index of plasma were calculated according to suggested formula. Anthropometric indices, lipid profiles, liver enzymes as well as abdominal ultrasonography and the status of vitamin D were assessed. The results showed that aspartate aminotransferase (AST) (44.22 ± 8.5 IU/L vs. 40.19 ± 8.75 IU/L, p-value = 0.039) AIP (0.767 ± 0.142 vs. 0.6417 ± 0.139, p < 0.001) and VAI (9.28 ± 3.25 vs. 7.048 ± 2.415, p = 0.001) were significantly higher in patients with vitamin D deficiency compared to those with vitamin D sufficiency. The positive correlations between Vaspin levels and vitamin D were found to be remarkably significant in both males and females (r = 0.437; P = 0.004; P < 0.001, r = −0.709, respectively. In both males and females serum vitamin D concentrations were negatively associated with AIP. Partial correlations controlling for age and sex showed that vitamin D is significantly and inversely associated with AIP, VAI, AST, and ALT. Additionally, vitamin D levels correlated directly with vaspin.

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