scholarly journals KENASABAN FOSFAT SERUM, C-REAKTIF PROTEIN DAN FETUIN A DI PASIEN GINJAL TAHAP AKHIR DENGAN HEMODIALISIS

2018 ◽  
Vol 22 (2) ◽  
pp. 187
Author(s):  
Indranila KS ◽  
Heri Winarto ◽  
Purwanto AP
Keyword(s):  
Reference Range ◽  
Serum Phosphate ◽  
Serum Phosphate Level ◽  
Cross Sectional ◽  
Fetuin A ◽  
Hemodialysis Unit ◽  
Spearman Correlation Test ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Patients with end-stage renal disease (ESRD) who undergo hemodialysis have chronic inflammation caused by several factors,including biocompatibility of dialyzer membran. Inflammation will decrease the fetuin A level in serum. The elevation of the markerinflammation (CRP), hyperphosphatemia and decrease of fetuin A level are the risk faktors for vascular calcification. The aim of thisstudy was to know the relationship between serum phosphate, CRP and fetuin A levels in ESRD patients who underwent hemodialysis. Theresearch was carried out by observational cross sectional analytical approach with consecutive sampling on 31 ESRD patients undergoingchronic hemodialysis in the Hemodialysis Unit of the Dr.Kariadi Hospital, by examining levels of CRP by ELISA, serum phosphate byPhosphomolibdate methods and fetuin A by ELISA. The relationships between phosphate serum and CRP, CRP and fetuin A, phosphateserum and fetuin A were analyzed using Spearman correlation test. In this study it was found that 100% of subjects had CRP levels >0.3mg/dL (reference range 0.1-0.3 mg/dL); 61.3% of subjects had serum phosphate >5.1 mg/dL (reference range 2.5-5.1 mg/dL) and allsubjects (100%) had fetuin A levels <0.5 ng/mL (reference range 0.5-1 ng/mL). There was a moderate positive significant correlationbetween serum phosphate and CRP (p=0.024 and r=0.404), there was a strong negative significant correlation between CRP and fetuinA (p=0.000 and r=-0.628). No significant correlation between the phosphate serum and fetuin A (p=0.365 and r=-0.168) was found.Based on this study, it was found that the higher serum phosphate level resulted in a higher CRP and lower fetuin A.

scholarly journals Risk Estimation of Aortic Stiffness in Patients with End Stage Renal Disease on Maintenance Haemodialysis

2019 ◽  
Vol 9 (1) ◽  
pp. 59-62
Author(s):  
Muhammad Abdur Razzak ◽  
Debasish Kumar Saha ◽  
Muhammad Ehsan Jalil ◽  
Mohammad Omar Faruque Miah ◽  
Abu Noim Md Abdul Hai ◽  
...  
Keyword(s):  
Renal Disease ◽  
Serum Calcium ◽  
End Stage Renal Disease ◽  
Aortic Stiffness ◽  
Serum Phosphate ◽  
Serum Phosphate Level ◽  
Maintenance Haemodialysis ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: The stiffness of the large elastic arteries increase the morbidity and mortality. The purpose of the present study was to estimate the risk of aortic stiffness among end stage renal disease patients on maintenance haemodialysis. Methods: This cross-sectional study was carried out in the Department of Nephrology at National Institute of Kidney Diseases and Urology (NIKDU), Dhaka and National Institute of Cardiovascular Disease and Hospital (NICVD), Dhaka, Bangladesh from January 2013 to December 2014 for a period of two years. Chronic kidney disease in stage 5 [CKD-5(D)] patients older than 18 years on maintenance haemodialysis (MHD) for more than 3 months were designated as case group and age and sex matched non CKD patients were considered as control group. Serum calcium, serum albumin, serum phosphate and iPTH were estimated by semi-automated biochemistry analyzer from the Department of Biochemistry of NIKDU, Dhaka and NICVD, Dhaka. Plain Xray abdomen in lateral view was performed for all patients. Result: A total number of 100 patients were enrolled for this study of which 50 patients were in end stage renal disease (ESRD) group and the rest 50 patients were in non-CKD group. Mean (±SD) aortic stiffness index was significantly higher (P<0.001) among ESRD population (3.27±1.70) compared to non CKD group of population (2.00±0.73). Mean (±SD) serum calcium (corrected) level was significantly high (P<0.001) in ESRD patients (9.79±0.87) compared to non CKD group of population (9.13±0.70). Mean (±SD) serum phosphate level was significantly higher (P<0.001) in ESRD patients (5.71±0.96) compared to non CKD group of population (4.20±0.59). However, mean (±SD) iPTH level showed no significant difference between ESRD (25.33±51.98) and non CKD group of population (38.53±19.52). Conclusion: In conclusion, aortic stiffness is significantly higher among ESRD subjects. Birdem Med J 2019; 9(1): 59-62

scholarly journals Risk Estimation of Aortic Stiffness in Patients with End Stage Renal Disease under Maintenance Haemodialysis

2019 ◽  
Vol 14 (2) ◽  
pp. 67-70
Author(s):  
Md Rasul Amin ◽  
Abdur Razzak ◽  
GM Sadik Hasan ◽  
ANM Abdul Hai ◽  
Chayan Kumar Singho ◽  
...  
Keyword(s):  
Renal Disease ◽  
Serum Calcium ◽  
End Stage Renal Disease ◽  
Aortic Stiffness ◽  
Serum Phosphate ◽  
Serum Phosphate Level ◽  
Maintenance Haemodialysis ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: The stiffness of the large elastic arteries increase the morbidity and mortality. Objective: The purpose of the present study was to estimate the risk of aortic stiffness among end stage renal disease patients under maintenance haemodialysis. Methodology: This case-control study was carried out in the Department of Nephrology at National Institute of Kidney Diseases and Urology (NIKDU), Dhaka and National Institute of Cardiovascular Disease and Hospital (NICVD), Dhaka, Bangladesh from January 2013 to December 2014 for a period of two (02) years. Chronic kidney disease in stage 5 [CKD-5(D)] patients older than 18 years on maintenance haemodialysis (MHD) for more than 3 months were designated as case group and age and sex matched non CKD patients were considered as control group. Serum calcium, serum albumin, serum phosphate and iPTH were estimated by semi-automated biochemistry analyzer from the Department of Biochemistry of NIKDU, Dhaka and NICVD, Dhaka. Plain X-ray abdomen in lateral view was performed for all patients. Result: A total number of 100 patients were enrolled for this study of which 50 patients were in end stage renal disease (ESRD) group and the rest 50 patients were in non-CKD group. Mean (±SD) aortic stiffness index was significantly higher (P<0.001) among ESRD population (3.27±1.70) compared to non CKD group of population (2.00±0.73). Mean (±SD) serum calcium (corrected) level was significantly high (P<0.001) in ESRD patients (9.79±0.87) compared to non CKD group of population (9.13±0.70). Mean (±SD) serum phosphate level was significantly higher (P<0.001) in ESRD patients (5.71±0.96) compared to non CKD group of population (4.20±0.59). However, mean (±SD) iPTH level showed no significant difference between ESRD (25.33±51.98) and non CKD group of population (38.53±19.52). Conclusion: In conclusionaortic stiffness is significantly higher among ESRD subjects. University Heart Journal Vol. 14, No. 2, Jul 2018; 67-70

scholarly journals Diabetic nephropathy as a cause of end-stage renal disease in Egypt: a six-year study

2004 ◽  
Vol 10 (4-5) ◽  
pp. 620-626 ◽  
Author(s):  
A. Afifi ◽  
M. El Setouhy ◽  
M. El Sharkawy ◽  
M. Ali ◽  
H. Ahmed ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Large Scale ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

The prevalence of diabetic nephropathy as a cause of end-stage renal disease [ESRD] in Egypt has been examined in small cross-sectional studies, with conflicting results. The need for a large-scale study prompted us to perform this 6-year multiple cross-sectional study. A sample of ESRD patients enrolled in the Egyptian renal data system was evaluated during the period 1996-2001 for the prevalence of diabetic nephropathy. Prevalence gradually increased from 8.9% in 1996, to 14.5% in 2001. The mean age of patients with diabetic nephropathy was significantly higher than that of patients with ESRD from other causes. Mortality was also significantly higher in diabetic patients with ESRD

scholarly journals Bone mineral density in Palestinian patients with end-stage renal disease and the related clinical and biochemical factors: Cross-sectional study

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0241201
Author(s):  
Zaher Nazzal ◽  
Shahd Khader ◽  
Hiba Zawyani ◽  
Mazen Abdallah ◽  
Osama Sawalmeh ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
End Stage Renal Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Introduction End-Stage Renal Disease (ESRD) is the ultimate result of chronic kidney disease (CKD). In Palestine, the prevalence of ESRD was 240.3 PMP which is comparable with the nearby countries. Accelerated bone loss among ESRD patients is attributed to abnormal bone turn over that leads to osteoporosis and osteopenia. The risk of fractures is increased four-fold in men and women on hemodialysis, which explains the importance of assessing the bone mineral density among these population. The goals of this study were to find the prevalence of osteoporosis in ESRD patients as determined by bone mineral density (BMD) at different sites and to determine whether BMD correlates with many other clinical parameters. Methods A cross-sectional study of 194 ESRD patients were recruited from the dialysis unit in An-Najah National University Hospital, Nablus, Palestine. The patients were on regular hemodialysis or peritoneal dialysis. BMD was measured at the lumbar spine and the hip using the dual-energy X-Ray absorptiometry (DEXA) and the value is expressed as T-score. The data were analyzed using SPSS, version 26. The relationship between BMD and the clinical and biochemical parameters among the ESRD patients was assessed. Results We found that 42.8% of ESRD patient had osteoporosis and 40.2% had osteopenia. There were significantly higher proportions of osteoporosis and osteopenia among patients >60 years of age (p<0.005). Patients with osteoporosis and osteopenia had significantly higher serum levels of PTH (792.9 and 469.7) (p<0.05). BMD decreases as the duration of dialysis (39.0 months Vs. 56.8 months), (p<0.05). We found no significant difference between patients on hemodialysis or peritoneal dialysis. Conclusion This study showed that Palestinian patients with ESRD have low BMD at the hip and spine. The observed high serum level of PTH was associated with low BMD. Those patients should be closely monitored especially those with more than one risk factor. Moreover, more attention should be paid for these category of patients to decrease the incidence of falling down and the resulting fractures that might lead to mortality and morbidity.

scholarly journals Adherence to Hemodialysis and Associated Factors among End Stage Renal Disease Patients at Selected Nephrology Units in Rwanda: A Descriptive Cross-Sectional Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Marie Claire Mukakarangwa ◽  
Geldine Chironda ◽  
Busisiwe Bhengu ◽  
Godfrey Katende
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Associated Factors ◽  
Health Concern ◽  
Public Health Concern ◽  
Cross Sectional ◽  
Factors Associated ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Introduction. Worldwide, End Stage Renal Disease (ESRD) has become a public health concern increasing the number of patients maintained on hemodialysis prior to renal transplantation. Nonadherence to hemodialysis continues to impact on the care of ESRD patients, causing high increase in morbidity and mortality. Purpose of the Study. The purpose of this study was to determine the level of adherence to hemodialysis and the associated factors among End Stage Renal Disease (ESRD) patients in selected nephrology units in Rwanda. Methods. This was a descriptive cross-sectional design involving 41 participants. Participants were recruited using a purposive sampling technique. Demographic and adherence to hemodialysis data were collected with the use of structured interview schedules. Descriptive statistics were used to describe the demographic variables and the level of adherence to hemodialysis. Inferential statistics of chi-square was used to establish factors associated with adherence to hemodialysis. Results. Twenty-one (51%) of ESRD participants adhered highly (scores < 80%) to HD. Seventeen (42%) adhered moderately (70–79%) to HD while three (7%) had low level of adherence to HD (below 70%). The factors associated with adherence to hemodialysis were age (mean = 27; 95% CI 26.76–29, 17; p = 038) and religion (95% CI 26.29–60.12, p = 003). Frequencies of education of health care workers about the importance of not missing dialysis (95% CI 26.71–42.56, p = .000), perceived relative importance of hemodialysis (95% CI 20.44–27.76, p = .020), and experiencing difficulties during the procedure (95% CI 20.80–28.36, p = .004) were significantly associated with adherence to hemodialysis. Conclusion. Adherence to hemodialysis is still a public health concern in Rwanda. Health care providers and particularly nurses should continue to advocate for adherence to HD for better health outcomes. Further research is needed to identify the barriers to HD in Rwanda.

scholarly journals Dialysis dose in end-stage renal disease patients undergoing regular hemodialysis at Ibn-Sena and AlNao hospitals in Sudan

2019 ◽  
Vol 9 (1) ◽  
pp. e10-e10
Author(s):  
Essamaddin A Ibrahim
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Average Duration ◽  
Descriptive Study ◽  
Dialysis Dose ◽  
Cross Sectional ◽  
Excretory Function ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Introduction: Ne Hemodialysis (HD) plays a fundamental role in the treatment of end-stage renal disease (ESRD) patients. A minimal duration between 9 to 12 hours per week is required for maintaining adequate HD to restore excretory function of the kidney. Objectives: To measure the average duration of HD among Sudanese patients, and compare with the universal recommended duration. Patients and Methods: A cross-sectional, descriptive study at IBN-SENA hospital and ALNAO teaching hospital was conducted. All patients were subjected to full medical history and examination to identify their age, gender, original kidney disease and duration and route of HD. Results: A total of 121 ESRD patients under regular HD participated in this study. The majority [78 (64.5%)] had an average duration of HD of 8 h/wk. Conclusion: A large proportion of our patients on HD are below target dialysis dose; mainly due to reducing in the number of sessions per week and average duration per each session.

scholarly journals Factors Affecting the Burden on Family Caregivers of ESRD Patients

2019 ◽  
Vol 31 (Number 2) ◽  
pp. 22-27
Author(s):  
E H Rabin ◽  
E Hogue ◽  
SN Ahmad ◽  
S Shikder
Keyword(s):  
Family Caregivers ◽  
Additional Stress ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Medical College ◽  
Care Givers ◽  
Care Giving ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Patients of chronic kidney disease on hemodialysis face varieties of challenges and comorbid conditions need regular assistance from family caregiver. Caregivers of end stage renal disease (ESRD) have to bear loads of patient's daily activities, cares, medication, carrying to hospital, managing their psycho-social and financial demands which impose additional stress and burden among them. The study was conducted to evaluate the effect of care giving of patients with ESRD and to analyze the factors associated with it This cross sectional, observational and descriptive type of study was conducted in the Department of Nephrology and Psychiatry of Holy Family Red Crescent Medical College during the period of July 2018 to June 2019. Fifty family caregivers of age more than 18 years providing care or assistance to a relative with ESRD on dialysis were included. The burden of the care giver was assessed by a verified and culturally adopted Bangla-version of 22 factor Zarit Burden Interview (ZBI-B) scale. Difference of burden was not statistically significant considering its sex, marital status, place of residence, education level, religion, relation with patient, living in same house with patient or duration of the care giving of the patients (p>0.05). In JO% cases care givers had little or no burden, 26% mild to moderate, 22% moderate and 2% severe burden. So, in Bangladesh caregiving to ESRD patients imposes no or little burden on majority offamdy caregivers.

scholarly journals Thyroid Hormone Abnormalities in Hemodialyzed Patients: Low Triiodothyronine As Well As High Reverse Triiodothyronine Are Associated With Increased Mortality

2012 ◽  
pp. 495-501 ◽  
Author(s):  
J. HORÁČEK ◽  
S. DUSILOVÁ SULKOVÁ ◽  
M. KUBIŠOVÁ ◽  
R. ŠAFRÁNEK ◽  
E. MALÍŘOVÁ ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Reference Range ◽  
Rank Test ◽  
Nonthyroidal Illness ◽  
Log Rank Test ◽  
Low T3 ◽  
Stage Renal Disease ◽  
End Stage ◽  
The Impact ◽  
Esrd Patients

Numerous abnormalities of thyroid hormones in end-stage renal disease (ESRD) have been described. Our aim was to analyze the impact of these abnormalities on survival. In 167 hemodialyzed ESRD patients, TSH and thyroid hormone levels (T4, fT4, T3, fT3, rT3) were determined. The patients were then prospectively followed up for up to 5 years and the possible impact of any observed abnormalities on their mortality was studied. Only 16.8 % patients had all six tests within the reference range. The pattern of nonthyroidal illness syndrome was found in 56.3 %. Low T3 was particularly common (44.3 %), and clearly associated with increased 6- and 12-month mortality and decreased overall survival (log rank test, P=0.007). Independent of T3 levels (Spearman correlation, NS), increased rT3 was more frequently observed (9.9 %) than expected from the literature, and was also related to increased mortality and decreased survival (log rank test, P=0.021). Increased rT3 may be more common in ESRD patients than previously described, and together with decreased T3 it may serve as an indicator of poor prognosis in subsequent months.

scholarly journals Drug utilization pattern and selected biochemical parameters in pre- and post-hemodialysis state in the end stage renal disease patients: a cross sectional study at a tertiary care hospital

2019 ◽  
Vol 8 (9) ◽  
pp. 2074
Author(s):  
S. P. Gokulraj ◽  
Surendra Kumar Bouddh ◽  
J. Rajesh
Keyword(s):  
Serum Albumin ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Significant Difference ◽  
Blood Haemoglobin ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: Chronic kidney disease can progress to end-stage kidney failure (ESRD), which is fatal without artificial filtering (dialysis) or a kidney transplant.Methods: The ESRD patients of either gender age >18 years who were diagnosed by nephrologist as ESRD and are on haemodialysis regularly included for the study.Results: The blood urea, serum creatinine, phosphorous, potassium levels were reduced significantly in post – haemodialysis condition, but, there was not much weight reduction after haemodialysis. Serum albumin, serum sodium and blood haemoglobin levels were almost unchanged in post – haemodialysis state. There was no significant difference between the pre and post haemodialysis parameters- serum Na+ serum albumin and blood hemoglobulin. Out of 75 ESRD patients, almost all patients 74 (98.7%) prescribed tablet Livogen, 73 (97.3%) patients given Inj. EPO, 55 (73.3%) tab Nicardia, 54 (76%) tab Sodamint, 43 (57.3%) capsule Alpha D3, 40 (53.3%) tab Shelcal. While between 12 (16%) to 20 (26%) patients prescribed tab Nodosis, tab Metoprolol, tab Febuget, tab Ecosprin, and tab Rantac. Only 1 (1.3%) to 9 (12%) patients received tablet Augmentin, tab Arkamine, tab Carvedilol, tab Para 500, tab Atorvas, Human mixtard, tab Calcicard, tab Minipress XL, tab Dytor, and tab Clopilet.Conclusions: The available two models of treatment, i.e., haemodialysis and poly pharmacy at hospital setup to face the challenges associated with the ESRD, and even outcome after application of both these two models of therapies did not provide optimal normal healthy life status to ESRD patients.

THE TREATMENT COST OF END-STAGE RENAL DISEASE WITH HEMODIALYSIS IN THU DUC DISTRICT HOSPITAL

2016 ◽  
pp. 34-40
Author(s):  
Hoang Lan Nguyen ◽  
Van Hung Phu
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
District Hospital ◽  
Financial Burden ◽  
Cross Sectional ◽  
Poor Households ◽  
Out Of Pocket Payments ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Background: Treatment of end-stage renal disease (ESRD) patients resulted in extension of their life expectancy, however they poses a financial burden on patients and their households. The study was conducted at Thu Duc district Hospital with the aim at calculating the monthly medical direct cost of ESRD patients with hemodialysis, and assessing financial burden of the disease treatment on their households. Method: A cross-sectional descriptive study. Cost data was collected by interviewing 100 patients dialysed. Financial invoices of patients were used to calculate monthly medical direct costs on the basis of health care payer’s perspective. Results: The financial burden of the treatmen was measured by proportion out-ofpocket payment from total household income remaining after subsistence needs met. The results showed that the monthly average total medical cost was 9,591,443 VND per person ($5,377US per year per person) in which out of pocket payments of patient was 3,192,610 VND. Out-of-pocket cost was 80.5% of total income remaining after subsistence needs met of the near poor households and exceeded near 7 times of that of the poor households every month. Key words: end-stage renal disease, hemodialysis, direct medical costs, out-of-pocket, financial burden

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