Taste Profiles from Single Human Taste Papillae

1978 ◽  
Vol 47 (1) ◽  
pp. 279-286 ◽  
Author(s):  
James T. Kuznicki

Earlier psychophysical research on single human fungiform taste papillae employed a procedure which limited subjects to selecting only one taste to describe the sensations they experienced. That procedure precludes the possibility of determining whether single papillae can mediate complex tastes, i.e., tastes consisting of more than one sensation experienced simultaneously. By using highly trained subjects and allowing them freedom to describe all sensations simultaneously elicited by a given taste stimulus, single papilla taste profiles were obtained. It is suggested that obtaining taste profiles may increase the utility of single papillae as models for study of the taste system.

1997 ◽  
Vol 272 (1) ◽  
pp. C1-C26 ◽  
Author(s):  
R. E. Stewart ◽  
J. A. DeSimone ◽  
D. L. Hill

Major advances in the understanding of mammalian gustatory transduction mechanisms have occurred in the past decade. Recent research has revealed that a remarkable diversity of cellular mechanisms are involved in taste stimulus reception. These mechanisms range from G protein-and second messenger-linked receptor systems to stimulus-gated and stimulus-admitting ion channels. Contrary to widely held ideas, new data show that some taste stimuli interact with receptive sites that are localized on both the apical and basolateral membranes of taste cells. Studies of taste system development in several species indicate that the transduction pathways for some stimuli are modulated significantly during the early postnatal period. In addition, recent investigations of adult peripheral gustatory system plasticity strongly suggest that the function of the Na+ sensing system can be modulated by circulating hormones, growth factors, or cytokines.


2020 ◽  
Vol 29 (3) ◽  
pp. 429-435
Author(s):  
Patricia C. Mancini ◽  
Richard S. Tyler ◽  
Hyung Jin Jun ◽  
Tang-Chuan Wang ◽  
Helena Ji ◽  
...  

Purpose The minimum masking level (MML) is the minimum intensity of a stimulus required to just totally mask the tinnitus. Treatments aimed at reducing the tinnitus itself should attempt to measure the magnitude of the tinnitus. The objective of this study was to evaluate the reliability of the MML. Method Sample consisted of 59 tinnitus patients who reported stable tinnitus. We obtained MML measures on two visits, separated by about 2–3 weeks. We used two noise types: speech-shaped noise and high-frequency emphasis noise. We also investigated the relationship between the MML and tinnitus loudness estimates and the Tinnitus Handicap Questionnaire (THQ). Results There were differences across the different noise types. The within-session standard deviation averaged across subjects varied between 1.3 and 1.8 dB. Across the two sessions, the Pearson correlation coefficients, range was r = .84. There was a weak relationship between the dB SL MML and loudness, and between the MML and the THQ. A moderate correlation ( r = .44) was found between the THQ and loudness estimates. Conclusions We conclude that the dB SL MML can be a reliable estimate of tinnitus magnitude, with expected standard deviations in trained subjects of about 1.5 dB. It appears that the dB SL MML and loudness estimates are not closely related.


1999 ◽  
Vol 13 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Laurence Casini ◽  
Françoise Macar ◽  
Marie-Hélène Giard

Abstract The experiment reported here was aimed at determining whether the level of brain activity can be related to performance in trained subjects. Two tasks were compared: a temporal and a linguistic task. An array of four letters appeared on a screen. In the temporal task, subjects had to decide whether the letters remained on the screen for a short or a long duration as learned in a practice phase. In the linguistic task, they had to determine whether the four letters could form a word or not (anagram task). These tasks allowed us to compare the level of brain activity obtained in correct and incorrect responses. The current density measures recorded over prefrontal areas showed a relationship between the performance and the level of activity in the temporal task only. The level of activity obtained with correct responses was lower than that obtained with incorrect responses. This suggests that a good temporal performance could be the result of an efficacious, but economic, information-processing mechanism in the brain. In addition, the absence of this relation in the anagram task results in the question of whether this relation is specific to the processing of sensory information only.


2006 ◽  
pp. 28-29
Author(s):  
Suzanne Sollars
Keyword(s):  

Author(s):  
Witalo Kassiano ◽  
Bruna Daniella de Vasconcelos Costa ◽  
João Pedro Nunes ◽  
Andreo Fernando Aguiar ◽  
Belmiro F. de Salles ◽  
...  

AbstractSpecialized resistance training techniques (e.g., drop-set, rest-pause) are commonly used by well-trained subjects for maximizing muscle hypertrophy. Most of these techniques were designed to allow a greater training volume (i.e., total repetitions×load), due to the supposition that it elicits greater muscle mass gains. However, many studies that compared the traditional resistance training configuration with specialized techniques seek to equalize the volume between groups, making it difficult to determine the inherent hypertrophic potential of these advanced strategies, as well as, this equalization restricts part of the practical extrapolation on these findings. In this scenario, the objectives of this manuscript were 1) to present the nuance of the evidence that deals with the effectiveness of these specialized resistance training techniques and — primarily — to 2) propose possible ways to explore the hypertrophic potential of such strategies with greater ecological validity without losing the methodological rigor of controlling possible intervening variables; and thus, contributing to increasing the applicability of the findings and improving the effectiveness of hypertrophy-oriented resistance training programs.


2018 ◽  
Vol 54 (3) ◽  
pp. 670-678 ◽  
Author(s):  
Xiaojing Tian ◽  
Jun Wang ◽  
Ruiqian Shen ◽  
Zhongren Ma ◽  
Mingsheng Li
Keyword(s):  

1995 ◽  
Vol 48 (6) ◽  
Author(s):  
P. Palatini ◽  
S. Bongiovi ◽  
L. Mario ◽  
P. Mormino ◽  
A.C. Pessina ◽  
...  

2004 ◽  
Vol 96 (2) ◽  
pp. 531-539 ◽  
Author(s):  
Mark S. Tremblay ◽  
Jennifer L. Copeland ◽  
Walter Van Helder

The purpose of this study was to determine the acute anabolic and catabolic hormone response to endurance and resistance exercise bouts of equal volume in subjects with differing training status. Twenty-two healthy men were recruited who were either resistance trained ( n = 7), endurance trained ( n = 8), or sedentary ( n = 7). Three sessions were completed: a resting session, a 40-min run at 50-55% maximal oxygen consumption, and a resistance exercise session. Expired gases were monitored continuously during exercise, and the endurance and resistance exercise sessions were individually matched for caloric expenditure. Blood samples were drawn before exercise and 1, 2, 3, and 4 h after the start of the exercise. Plasma was analyzed for luteinizing hormone, dehydroepiandrosterone sulfate, cortisol, and free and total testosterone. Androgens increased in response to exercise, particularly resistance exercise, whereas cortisol only increased after resistance exercise. Dehydroepiandrosterone sulfate levels increased during the resistance exercise session and remained elevated during recovery in the resistance-trained subjects. Endurance-trained subjects displayed less pronounced changes in hormone concentrations in response to exercise than resistance-trained subjects. After an initial postexercise increase, there was a significant decline in free and total testosterone during recovery from resistance exercise ( P < 0.05), particularly in resistance-trained subjects. On the basis of the results of this study, it appears that the endogenous hormone profile of men is more dependent on exercise mode or intensity than exercise volume as measured by caloric expenditure. The relatively catabolic environment observed during the resistance session may indicate an intensity-rather than a mode-dependent response.


1991 ◽  
Vol 9 (1) ◽  
pp. 47-70 ◽  
Author(s):  
Minoru Tsuzaki

In an investigation of interactions between scales and intervals in music cognition, melodic intervals were judged in three preceding-scale contexts: diatonic, chromatic, and no scale. Musically less trained and highly trained subjects compared standard and comparison intervals using three response categories: smaller, equal, and larger. Standard intervals began with notes B or C and ascended by 100, 150, or 200 cents. Discriminal dispersion was estimated for each combination of standard and comparison intervals, based on the assumption that the bandwidth of subjective equality was constant. The dispersion width and the modal dispersion corresponded to the equality- related and sizerelated aspects of interval judgments, respectively. The size-related aspect was strongly influenced by the size of the standard intervals. The point of balance, which corresponds to the traditional point of subjective equality (PSE), tended to be smaller as the standard interval became larger. It was, however, anchored to the point of musical equality when the standard interval began with the tonic. The equality-related aspect was influenced by the relationship between the preceding scale and the intervals to be judged. The diatonic preceding scale differentiated the intervals by their positions along the scale, that is, a sharp discriminal dispersion was estimated when the judged intervals were congruent with the diatonic scale. Such differentiation was not clearly observed in the chromatic condition. The relationship between these two aspects of interval judgment and the subject's musical ability is discussed.


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