Effects of Attention State on Electrodermal Activity during Auditory Stimulation of Children

1992 ◽  
Vol 75 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Masamitsu Shibagaki ◽  
Tadashige Yamanaka ◽  
Takeshi Furuya

During passive and active listening tasks electrodermal activity of 49 healthy school children was studied. The procedure included baseline recording, a passive listening task, instructions, and simple and discriminative active-listening tasks. On the passive task from Trials 1 to 10, habituation of the amplitude of the skin conductance response (SCR) occurred. Habituation of SCR amplitude did not occur during the active tasks. The children seemed to pay more attention during the active tasks than during the passive task, since the need to press the key is apt to require and may even increase general attention. As for temporal variables of SCR, the frequency of spontaneous SCRs showed a significant negative correlation with SCR latency and rise time. Reaction time exhibited a significant negative correlation with age. An increase in reaction time was found during the discriminative active-listening task over that for the simple active-listening task during the course of 10 trials. The younger children (6–8 yr.) seemed to require longer to pay attention than the older ones (10–12 yr.). Children seemed to pay more attention during the discriminative than during the simple active-listening task, since the need to press the key for discrimination should require and is likely to increase general attention.

1993 ◽  
Vol 77 (1) ◽  
pp. 331-338 ◽  
Author(s):  
Masamitsu Shibagaki ◽  
Tadashige Yamanaka ◽  
Takeshi Furuya

Electrodermal activity during passive and active listening tasks of 18 children with Attention-Deficit Hyperactivity Disorder (ADHD) and 49 healthy school children was studied. The procedure included baseline recording, a passive listening task, instructions, and both simple and discriminative active-listening tasks. ADHD subjects tended to exhibit lower arousal as indicated by the decrease in amplitude of the skin conductance response. Present findings confirm classical observation that ADHD children have shorter attention spans.


1994 ◽  
Vol 79 (1) ◽  
pp. 403-410 ◽  
Author(s):  
Masamitsu Shibagaki ◽  
Masahiro Sakamoto ◽  
Takeshi Furuya

Age differences in characteristics of the attention process of electrodermal activity during passive and active Listening tasks were studied with 43 nursery and 49 primary school children and 38 university students. The procedure included baseline recording, a passive listening task, instruction, and an active listening task. Significant differences in skin conductance response (SCR) were found among the three age groups. The SCR became smaller for the groups of increasing ages only for the active listening task. As the trials progressed, there was a trend in the three age groups for decreasing SCR amplitude during the passive listening task.


1997 ◽  
Vol 84 (3) ◽  
pp. 967-975 ◽  
Author(s):  
Masamitsu Shibagaki ◽  
Takeshi Furuya

During passive and active listening tasks baseline respiratory sinus arrhythmia and heart-rate responses were studied of 18 children with Attention-Deficit Hyperactivity Disorder (ADHD) and 49 healthy school children. The experimental procedure included baseline recording (no task), a passive listening task, instructions, and both simple and discriminative active-listening tasks. ADHD subjects showed less respiratory sinus arrhythmia than normal children but were similarly responsive to tone stimuli.


2008 ◽  
Vol 28 (S 01) ◽  
pp. S61-S66 ◽  
Author(s):  
G. Cvirn ◽  
A. Rosenkranz ◽  
B. Leschnik ◽  
W. Raith ◽  
W. Muntean ◽  
...  

SummaryThrombin generation was studied in paediatric patients with congenital heart disease (CHD) undergoing cardiac surgery using the calibrated automated thrombography (CAT) in terms of the lag time until the onset of thrombin formation, time to thrombin peak maximum (TTP), endogenous thrombin potential (ETP), and thrombin peak height. The suitability to determine the coagulation status of these patients was investigated. Patients, material, methods: CAT data of 40 patients with CHD (age range from newborn to 18 years) were compared to data using standard coagulation parameters such as prothrombin (FII), antithrombin (AT), tissue factor pathway inhibitor (TFPI), prothrombin fragment 1.2 (F 1.2), thrombin-antithrombin (TAT), activated partial thromboplastin time (aPTT), and prothrombin time (PT). Results: A significant positive correlation was seen between ETP and FII (p < 0.01; r = 0.369), as well as between peak height and F II (p < 0.01; r = 0.483). A significant negative correlation was seen between ETP and TFPI values (p < 0.05; r = –0.225) while no significant correlation was seen between peak height and TFPI. A significant negative correlation was seen between F 1.2 generation and ETP (p < 0.05; r = –0.254) and between F 1.2 generation and peak height (p < 0.05; r = –0.236). No correlation was seen between AT and ETP or peak. Conclusions: CAT is a good global test reflecting procoagulatory and inhibitory factors of the haemostatic system in paediatric patients with CHD.


2019 ◽  
Vol 19 (2) ◽  
pp. 120-126
Author(s):  
J. Wei ◽  
Y. Yu ◽  
Y. Feng ◽  
J. Zhang ◽  
Q. Jiang ◽  
...  

Background: Homocysteine (Hcy) has been suggested as an independent risk factor for atherosclerosis. Apolipoprotein M (apoM) is a constituent of the HDL particles. The goal of this study was to examine the serum levels of homocysteine and apoM and to determine whether homocysteine influences apoM synthesis. Methods: Serum levels of apoM and Hcy in 17 hyperhomocysteinemia (HHcy) patients and 19 controls were measured and their correlations were analyzed. Different concentrations of homocysteine (Hcy) and LY294002, a specific phosphoinositide 3- kinase (PI3K) inhibitor, were used to treat HepG2 cells. The mRNA levels were determined by RT-PCR and the apoM protein mass was measured by western blot. Results: We found that decreased serum apoM levels corresponded with serum HDL levels in HHcy patients, while the serum apoM levels showed a statistically significant negative correlation with the serum Hcy levels. Moreover, apoM mRNA and protein levels were significantly decreased after the administration of Hcy in HepG2 cells, and this effect could be abolished by addition of LY294002. Conclusions: resent study demonstrates that Hcy downregulates the expression of apoM by mechanisms involving the PI3K signal pathway.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Machiko Nakagawa ◽  
Hidenobu Ohta ◽  
Rinshu Shimabukuro ◽  
Yoko Asaka ◽  
Takayo Nakazawa ◽  
...  

AbstractThe purpose of the present study is to examine the association between toddlers' sleep arrangements and their nighttime sleep duration and other sleep variables. For this investigation, we performed a study in which child activity and sleep levels were recorded using actigraphy. The parents of 1.5-year-old toddlers (n = 106) were asked to attach an actigraphy unit to their child’s waist with an adjustable elastic belt and complete a sleep diary for 7 consecutive days. Questionnaires were used to assess the sleep arrangements of the toddlers. There was a significant negative correlation between nap duration and nighttime sleep duration, suggesting that longer nap sleep induces shorter nighttime sleep duration. Among the sleep arrangements, such as nighttime breastfeeding or co-sleeping, only nighttime breastfeeding predicted shorter nighttime sleep duration. Our findings indicate that shorter naps induce a longer nighttime sleep in 1.5-year-old toddlers while nighttime breastfeeding decreases their nighttime sleep duration.


Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1061
Author(s):  
Wajdy J. Al-Awaida ◽  
Baker Jawabrah Al Hourani ◽  
Samer Swedan ◽  
Refat Nimer ◽  
Foad Alzoughool ◽  
...  

The outbreak of coronavirus disease 2019 (COVID-19), by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly developed into a worldwide pandemic. Mutations in the SARS-CoV-2 genome may affect various aspects of the disease including fatality ratio. In this study, 553,518 SARS-CoV-2 genome sequences isolated from patients from continents for the period 1 December 2020 to 15 March 2021 were comprehensively analyzed and a total of 82 mutations were identified concerning the reference sequence. In addition, associations between the mutations and the case fatality ratio (CFR), cases per million and deaths per million, were examined. The mutations having the highest frequencies among different continents were Spike_D614G and NSP12_P323L. Among the identified mutations, NSP2_T153M, NSP14_I42V and Spike_L18F mutations showed a positive correlation to CFR. While the NSP13_Y541C, NSP3_T73I and NSP3_Q180H mutations demonstrated a negative correlation to CFR. The Spike_D614G and NSP12_P323L mutations showed a positive correlation to deaths per million. The NSP3_T1198K, NS8_L84S and NSP12_A97V mutations showed a significant negative correlation to deaths per million. The NSP12_P323L and Spike_D614G mutations showed a positive correlation to the number of cases per million. In contrast, NS8_L84S and NSP12_A97V mutations showed a negative correlation to the number of cases per million. In addition, among the identified clades, none showed a significant correlation to CFR. The G, GR, GV, S clades showed a significant positive correlation to deaths per million. The GR and S clades showed a positive correlation to number of cases per million. The clades having the highest frequencies among continents were G, followed by GH and GR. These findings should be taken into consideration during epidemiological surveys of the virus and vaccine development.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A153-A154
Author(s):  
Huisu Jeon ◽  
Sonhye Jeoung ◽  
Goeun Kim ◽  
Hyeyoung An ◽  
Hyojin Nam ◽  
...  

Abstract Introduction Bedtime Procrastination (BP) is defined as the behavior of going to bed later than intended, despite the absence of external factors. Bedtime procrastination is also prevalent among insomnia patients, and is associated with various sleep problems. Recent studies suggest emotional regulation as a mechanism of the procrastination behavior that is the conceptual foundation of bedtime procrastination. Emotional regulation difficulties are also associated with insomnia, but there is still a lack of research on the relationship between insomnia, emotional regulation strategies and bedtime procrastination. Thus, the study assumed that severity of insomnia would affect bedtime procrastination, and examined the moderating effect of the emotional regulation strategies in this relationship. Methods This study was conducted in 376 adults (mean age 23.73 ±2.14 years, 84.6% females). Participants were asked to answer Bedtime procrastination scale (BPS), an emotional regulation strategy checklist, and the Insomnia severity scale (ISI). Results As a result, a significant positive correlation was found between insomnia severity and bedtime procrastination (r=.286, p&lt;.01), and avoidant/distractive regulation style (r=.101, p&lt;.05). active regulation style (r=-.172, p&lt;.01) and support seeking regulation style (r=-.102, p&lt;.01) showed a significant negative correlation with the severity of insomnia. Bedtime procrastination behavior showed significant negative correlation only with active regulation style (r=-.151, p&lt;.01). Support seeking regulation style moderated the relationship between insomnia and bedtime procrastination behavior (B=.0165, 95%, CI=.0014, .0316). The interaction effect between insomnia and support seeking regulation style was also significant (∆R^2=.0112, p&lt;.05), indicating that the effect of insomnia on bedtime procrastination depends on the level of use of the support seeking regulation style. Conclusion These findings suggest that the level of support seeking regulation style is meaningful in terms of how insomnia affects bedtime procrastination. Support (if any) This work was supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea(NRF-2018S1A5A8026807)


2021 ◽  
pp. 1-8
Author(s):  
Foad Alzoughool ◽  
Huda Al Hourani ◽  
Manar Atoum ◽  
Sajedah Bateineh ◽  
Hanan Alsheikh ◽  
...  

BACKGROUND/AIM: The newly described proteins adropin and irisin are a highly conserved polypeptide that plays essential roles in metabolic and energy homeostasis, insulin resistance, and fat browning. The aim of this study is to evaluate the circulating levels of serum adropin and irisin in type 2 diabetes mellitus (T2DM) patients and also to elucidate possible relationships between serum adropin and irisin levels with anthropometric obesity indices and biochemical parameters. SUBJECTS AND METHODS: Single-center prospective observational study included 90 T2DM patients referred to the diabetes outpatient clinic. Height, weight, and waist circumference (WC) were measured. Body mass index (BMI) and waist to height ratio (WHtR) were calculated. Fasting blood glucose, glycosylated hemoglobin, serum lipids, creatinine, urea, and blood urea nitrogen were evaluated. Estimated glomerular filtration rate (GFR) was calculated, serum adropin and irisin were evaluated. RESULTS: The results showed a significant positive correlation between adropin and irisin in females but not in males (r = 0.311; P = 0.042). In males’ group, serum adropin levels showed significant negative correlation with serum glucose (–0.423, P = <  0.05), HbA1C (–0.364, P = <  0.05), and GFR (–0.355, P = <  0.05). In contrast, creatinine was showed a significant positive correlation with adropin in males (0.381, P = <  0.05). In females’ group, adropin showed a significant negative correlation with weight (–0.371, P = <  0.05), BMI (–0.349, P = <  0.05), WC (–0.402, P = <  0.01), and WHtR (–0.398, P = <  0.01). Contrary, in males’ group, serum irisin levels showed significant positive correlation with weight (0.338, P = <  0.05), BMI (0.332, P = <  0.05), WC (0.409, P = <  0.01), and WHtR (0.432, P = <  0.01). CONCLUSION: This study demonstrated that, in T2DM patients, circulating serum adrpoin correlated negatively with anthropometric obesity indices of obesity in females, while serum irisin was positively correlated with anthropometric obesity indices of obesity in males.


2003 ◽  
Vol 149 (6) ◽  
pp. 543-548 ◽  
Author(s):  
AG Rockall ◽  
SA Sohaib ◽  
D Evans ◽  
G Kaltsas ◽  
AM Isidori ◽  
...  

OBJECTIVE: Hepatic steatosis may occur in association with insulin resistance and obesity, two features commonly seen in Cushing's syndrome (CS). The aim of this report is to assess the prevalence of hepatic steatosis in patients with active CS using computed tomography (CT) and to identify any associations between hepatic steatosis, endocrine and biochemical variables and body fat distribution. PATIENTS AND MEASUREMENTS: We identified 50 patients with active CS in whom appropriate CT was available to allow measurement of liver and spleen attenuation. In 26 patients, abdominal fat measurements were also available. Serum markers of CS and liver function tests were recorded. RESULTS: Ten of 50 patients had a liver-to-spleen CT attenuation ratio (L/S) of less than 1, indicating hepatic steatosis. There was a significant negative correlation between both liver attenuation and L/S ratio with total abdominal fat area, visceral fat area, the percentage of visceral fat and the visceral to subcutaneous fat ratio; the strongest negative correlation was found between visceral fat area and L/S ratio (r=-0.638, P<0.001, n=26). L/S ratio positively correlated with alkaline phosphatase levels (r=+0.423, P=0.044, n=23) but with no other serum marker of CS activity or liver enzyme. CONCLUSIONS: We have demonstrated hepatic steatosis on CT in 20% of patients with active CS. The presence of hepatic steatosis was significantly correlated with total abdominal fat area and visceral fat area.


Sign in / Sign up

Export Citation Format

Share Document