Assessment of Memory for Remote Events

1975 ◽  
Vol 37 (1) ◽  
pp. 223-234 ◽  
Author(s):  
Larry R. Squire ◽  
Paul M. Chace ◽  
Pamela C. Slater

Two retrospective tests are described for the assessment of remote memory for past events. Both tests ask about former television programs broadcast for a single season from 1957 to 1972. One test asks about the plots of programs, and the other asks for judgments about their temporal order. The usefulness of such tests for experimental and clinical studies of memory is discussed.

1977 ◽  
Vol 20 (4) ◽  
pp. 742-751 ◽  
Author(s):  
Walter L. Cullinan ◽  
Elaine Erdos ◽  
Ronald Schaefer ◽  
Mary Ellen Tekieli

Recent findings indicate that the presence of formant transitions aids the perception of the order of stimuli in repeating sequences of vowels or consonant-vowel (CV) syllables. In this study, 12 listeners reported the perceived order of four vowels or CVs in repeating sequences. Stimuli ranged in duration from 75 to 300 msec in 25-msec steps. Four stimulus sequences were used (1) varying vowels (Vv), (2) CVs with varying consonants but a constant vowel (CvVc), (3) CVs with a constant consonant but varying vowels (CcVv), (4) CVs with consonants and vowels varying (CvVv). Percentage of correct identification of order was significantly higher and mean threshold duration significantly lower for the CvVv and CvVc conditions than for the Vv condition. Mean number of sequences per response was significantly smaller for the CvVv condition than for the other conditions. Threshold durations ranged from 100 msec for the CvVv sequences to 135 msec for the Vv sequences. Ordering performance was nearly perfect for stimulus durations of about 225 to 250 msec. The results support the hypothesis that as stimuli in repeating sequences more closely resemble connected speech, listeners can more easily correctly identify the order of the stimuli.


Author(s):  
Chhavi Asthana ◽  
Gregory M Peterson ◽  
Madhur D Shastri ◽  
Rahul P Patel

Abstract Background Clinical studies have reported inconsistent outcomes of glucosamine therapy in osteoarthritis patients. One possible reason could be the use of glucosamine products of varying quality. Objective Hence, this study aimed to assess the quality of glucosamine products marketed in Australia and India. This is the first study to investigate both the content and dissolution profiles of glucosamine products. Method The content and dissolution analysis of Australian (n = 25 brands) and Indian (n = 21 brands) glucosamine products was performed according to the criteria specified in the United States Pharmacopoeia (USP). Results The quality analysis revealed that 16% and 18% of Australian brands, as well as 24% and 19% of Indian brands, did not fulfil the USP content and dissolution criteria, respectively. In approximately half of these cases, the glucosamine content was only slightly below (<3%) that specified by the USP and dissolution was achieved within 15 min after the duration specified by the USP. Conclusions The majority of the brands did meet both the content and dissolution analysis criteria of the USP. The extent of deviation from the specified criteria for the other brands was probably insufficient to account for the significant variability in clinical effects. Hence, the study proposed that inter-patient pharmacokinetic variations in glucosamine could be another potential reason for inconsistent therapeutic effects. Highlights


1982 ◽  
Vol 28 (4) ◽  
pp. 672-675 ◽  
Author(s):  
P H Duncan ◽  
M R Wills ◽  
B J Smith ◽  
J Savory

Abstract A recently developed gel-filtration technique allows protein-bound calcium fractions to be separated and quantitated; the protein is separated under physiological conditions of pH, temperature, and concentrations of Na, Mg, and Ca to assure that the calcium-proteinate equilibrium is not disturbed. We used this gel-filtration technique to study the protein-bound calcium fractions in 18 patients with hyperparathyroidism, multiple myeloma, diabetes, osteoporosis, or liver cirrhosis. We calculated the amount of calcium bound per gram of protein for each of the three protein peaks and the intrinsic association constant (Ka) for calcium/albumin. Results with the multiple myeloma patients (three IgG, one IgA) indicated that IgG did not bind calcium appreciably, that IgA had about the same affinity as albumin for Ca, and that Ka was slightly low for one patient of the IgG type (79 L/mol) and normal for the other three myeloma patients (106, 90, and 91 L/mol). Results for patients with the other diseases were also essentially normal, except for the osteoporesis patients (two men, one woman), whose Ka values (69, 75, and 73 L/mol) were lower than normal.


Kant-Studien ◽  
2019 ◽  
Vol 110 (3) ◽  
pp. 413-436
Author(s):  
Hope C. Sample

Abstract When interpreters orient Kant’s philosophy of time in relation to McTaggart’s distinction among different ways of characterizing a temporal order, they claim that he is best described as endorsing an A series position according to which there is a metaphysically privileged present that determines the past and the future. Whether Kant might also be understood as a proponent of the B series - according to which there is no privileged present, but rather time is comprised of relations of earlier than, later than, and simultaneity - has not been discussed in the literature. I argue that, for Kant, the appearances can be described as an A series, while the phenomena are to be understood as a B series, neither of which is more fundamental than the other. Contra a common approach in the literature that neglects a metaphysical difference between appearances and phenomena, I argue Kant’s transcendental idealism about time is best understood in relation to his account of appearances and phenomena.


PMLA ◽  
1960 ◽  
Vol 75 (2) ◽  
pp. 30-34
Author(s):  
Ralph Paul de Gorog

Unlike the other countries of northern Europe, Finland has two official languages, Finnish and Swedish, a fact which is reflected in the emphasis placed on languages in the high-school curriculum. In the coastal communities from Lovisa to Turku (Åbo) on the southern shore, as well as in the towns from Pori (Björneborg) to Pietarsaari (Jakobstad), Swedish influence is stronger than anywhere else in Finland, and in many of these towns and villages only Swedish is spoken. In these communities and in the national capital itself, therefore, government workers and employees of business and industry are required to be fluent in both official languages. As in other bilingual countries, the use of two languages can be observed not only in official government documents, currency, postagestamps, and the like, but also in such things as signposts, advertisements, menus in restaurants, and time-tables. There are radio and television programs in both languages, and foreign films appear with two sets of subtitles on the same film, one in Finnish and one in Swedish. Thus whatever one's first language is, there is always ample opportunity to hear and see the other official language written. It should be mentioned, however, that ninety per cent of the population speaks Finnish as the first language and that very little Swedish can be heard in northern and in eastern Finland (except, of course, on the radio), but even in those Finnish-language areas, people are exposed to written Swedish on the label of virtually every product they buy, if nowhere else.


2021 ◽  
pp. 157-170
Author(s):  
I. I. Volkova ◽  
E. L. Proskurnova ◽  
T. T. D. Tran

The issues of the development of traditional news television in the context of a single information space are considered. The goal is to look at how much content creators and consumers agree in their predictions about the future of TV. The data of in-depth interviews were used as empirical material: professional television journalists (federal TV channels) and students (PFUR “Television” department) were interviewed. The contradictions between the two basic types of media consumption, which are characteristic of addressers and addressees of television messages, are revealed. It is shown that these contradictions explain the generational gap in the perception of modern news television programs, predetermine the decrease in TV consumption of news content from federal channels designed for a mass audience. The relevance of the work is due to the rethinking of the functions and prospects for the development of traditional TV by both professional broadcasters and consumers. The conclusion is made about the further development of news television. It is noted that, on the one hand (the opinion of professionals), traditional television broadcasting will be preserved while adjusting the agenda, rethinking interaction with the audience, changing the broadcasting paradigm, mastering new competencies by professional journalists and using the opportunities of the online space. On the other hand (students’ opinion), subject-to-object news broadcasting of federal channels will cease to exist when the generation of viewers and the funding model change.


2015 ◽  
Vol 10 (1) ◽  
pp. 67-72
Author(s):  
Alexandru Mircea NICOLAU ◽  
◽  
Vlad-Gabriel VASILESCU ◽  
Viorica MILICESCU ◽  
◽  
...  

Miniimplant recently became a way of orthodontic treatment. Compared to the other implants, miniimplants are relatively small, allowing them to be placed between the dental roots in various areas of the jaws and serve as skeletal anchorage for orthodontic tooth movements. The use of miniimplants for orthodontic skeletal anchorage may be an predictable and accurate alternative without requiring patient compliance, compared with conventional versions of anchorage. The paper presents a series of clinical cases seen and treated within the dental office of S.C. RANDI SRL and in the Department of Orthodontics at New York University College of Dentistry.


1988 ◽  
Vol 59 (01) ◽  
pp. 096-100 ◽  
Author(s):  
F W G Leebeek ◽  
J Stibbe ◽  
E A R Knot ◽  
C Kluft ◽  
M J Gomes ◽  
...  

SummaryA Dutch family, of which 13 members are heterozygotes, deficient for α2-antiplasmin (α2-AP) is reported. Clinical studies showed that 2 heterozygotes had a mild bleeding tendency, which presented as bleeding episodes after tooth extraction and after surgery and, in one patient, also as excessive menstruation. Laboratory investigations revealed an α2-AP activity of 62% (51-71) (median and range) and an antigen level of 60% (60-66). The plasminogen binding as well as the fibrin binding properties of α2-AP were normal. Plasminogen concentrations were significantly higher in the heterozygotes compared to the other family members. However, free plasminogen not bound to histidine-rich glycoprotein was not significantly different between these two groups. We propose that in this family the deficiency of α2-AP is due to a decreased synthesis of a normal α2-AP molecule. This present study brings the frequency of heterozygous α2-AP deficient patients with a bleeding tendency to 13 out of 59 heterozygotes reported in the literature.


Bioanalysis ◽  
2019 ◽  
Vol 11 (15) ◽  
pp. 1389-1403 ◽  
Author(s):  
Åsa Makower ◽  
Erik Arnelöf ◽  
Tommy Andersson ◽  
Per-Olof Edlund ◽  
Susanne Gustavsson ◽  
...  

Aim: Accumulation of heparan sulfate (HS) is associated with the neurodegenerative disorder Mucopolysaccharidosis type IIIA (MPS IIIA). Here, we compare HS levels in brain and cerebrospinal fluid (CSF) of MPS IIIA mice after treatment with a chemically modified sulfamidase (CM-rhSulfamidase). Materials & methods: Two LC–MS/MS methods were adapted from literature methodology, one to measure HS metabolites (HSmet), the other to measure digests of HS after heparinase treatment (HSdig). Results: The HSmet and HSdig methods showed similar relative reduction of HS in brain after CM-rhSulfamidase administration to MPS IIIA mice and the reduction was reflected also in CSF. Conclusion: The results of the two methods correlated and therefore the HSdig method can be used in clinical studies to determine HS levels in CSF from patients with MPS IIIA.


Author(s):  
Murray Pomerance

While Herrmann's twenty-four successful and one failed collaboration with Hitchcock – including films and television programs – featured compositional scoring to some degree, Herrmann's work on The Man Who Knew Too Much (1956) is a peculiar deviation in the pattern of their regular working relationship because there are only a very small number of composed cues. The bulk of Herrmann's work on this film, which involved some considerable legal machinations, consisted of two very different kinds of contribution, each of which can tell us something about the composer's talents, diligence, and sensitivity to film production. On one hand he was called upon to arrange "received" music, and this in a wide range from Moroccan folk tunes to elaborate symphonic work, and including the traditionalist hymn, "The Portents." On the other, he became a member of the cast, on this one occasion only in his filmic work with Hitchcock, playing the role of a conductor at a performance in the Royal Albert Hall. This chapter argues that, since the overall score of the film is essentially an acoustic quilt, we find here evidence of a talent for assemblage and backgrounding that Herrmann does not have opportunity to show in his other work with Hitchcock.


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