scholarly journals Thin-layer hydration method to prepare a green tea extract niosomal gel and its antioxidant performance

2021 ◽  
Vol 68 (1) ◽  
pp. 126-136
Author(s):  
U. Chasanah ◽  
N. Mahmintari ◽  
F. Hidayah ◽  
F.A. El Maghfiroh ◽  
D. Rahmasari ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Thin Layer ◽  
Green Tea ◽  
Chorioallantoic Membrane ◽  
Entrapment Efficiency ◽  
Physical Characteristics ◽  
Green Tea Extract ◽  
Gelling Agent ◽  
Niosomal Gel ◽  
Tea Extract

Abstract This study aimed to prepare a niosomal gel of green tea (Camellia sinensis) extract containing catechins, mostly epigallocatechin-3-gallate (ECGC), as a potent antioxidant. Niosomes can increase EGCG's stability and penetration into the skin for a better therapeutic effect. Niosomes were prepared by a thin-layer hydration method, were evaluated for their vesicle shape, particle size, polydispersity index, zeta potential and entrapment efficiency, and then incorporated into gels using sodium alginate as a gelling agent. Three niosomal gel formulations were prepared with different concentrations of niosomes green tea extract. Afterwards, organoleptic properties, chemical and physical characteristics, antioxidant activity, and stability and irritability of the niosomal gels were investigated. The different concentrations of green tea extract had a significant effect on the physical characteristics, but not on the chemical ones. Its antioxidant activity was determined using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging method. The 50% extract green tea niosomes gel showed the highest inhibition value (25.13%). The stability was determined by freeze–thaw and real-time methods; they showed a decrease in pH, but still within the pH range of skin. The irritability test used was the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) method, which showed no irritation for all formulas. In conclusion, 50% green tea extract niosomes gel results showed it to be the best formulation with optimal antioxidant results.

scholarly journals FORMULATION OF NIOSOMAL GEL CONTAINING GREEN TEA EXTRACT (CAMELLIA SINENSIS L. KUNTZE) USING THIN-LAYER HYDRATION

2017 ◽  
Vol 9 ◽  
pp. 38 ◽  
Author(s):  
Astrid Permatasari Isnan ◽  
Mahdi Jufri
Keyword(s):  
Thin Layer ◽  
Green Tea ◽  
Encapsulation Efficiency ◽  
Drug Stability ◽  
Epigallocatechin Gallate ◽  
Gelling Agent ◽  
Liposomal Drug ◽  
Molar Ratios ◽  
Niosomal Gel ◽  
Tea Extract

Objective: Green tea is known as a source of antioxidants. The most abundant of these is epigallocatechin gallate, which has been shown to modulatebiochemical pathways in the skin. Niosomes are an alternative to liposomal drug-vehicle systems, which have disadvantages such as cost and stability.To overcome the problem of low permeation of active substances through skin layers and to increase their stability, a topical antioxidant preparationbased on niosomes was prepared.Materials and Methods: To enhance drug stability, niosomal formulations were prepared in four different molar ratios of surfactant-to-cholesterol,that is, 3:1 (F1), 2:1 (F2), 1:1 (F3), and 0.5:1 (F4). These were prepared using the thin-layer method. The niosomal suspensions were evaluated forparticle size and distribution, lamellarity, encapsulation efficiency, and zeta potential, and were then incorporated into gels using hydroxypropylmethylcellulose as the gelling agent. The niosomal gels were evaluated for organoleptic properties, pH, viscosity, stability, and antioxidant activityusing 1,1-diphenyl-2-picrylhydrazyl.Results: Results for the suspensions showed that F1 had the best encapsulation efficiency but experienced separation after 7 days.Conclusions: Results for the niosomal gels (using F3) showed stable formulation without changes.

Synthesis and Antioxidant Activity of Resin of Chitosan Cerium Encapsulated Green Tea Extract Microspheres

2011 ◽  
Vol 194-196 ◽  
pp. 734-741
Author(s):  
Li Na Yu ◽  
Dong Feng Wang ◽  
Qing Li Yang ◽  
Hai Yan Li ◽  
Bing Jie Liu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Green Tea ◽  
Polyphenolic Compounds ◽  
Green Tea Extract ◽  
Emission Spectrometry ◽  
Narrow Particle Size Distribution ◽  
Human Beings ◽  
Free Radical Damage ◽  
Tea Extract

The purpose of this paper is to investigate a new type of resin of chitosan cerium encapsulated green tea extract microspheres (RCCM-GTE) prepared by the reversed-phase suspension cross-linking polymerization and study the scavenging activity against DPPH free radical. The results showed that RCCM-GTE was a type of deep brown-yellow spherical resin with smooth surface and it presented uniform and narrow particle size distribution as determined by the Laser Particles Sizer. The Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES), Fourier Transform Infrared Spectroscopy (FT-IR) and differential scanning calorimetry (DSC) study demonstrated that there was cerium existing in RCCM-GTE. The polyphenolic compounds existed in RCCM-GTE and the total content of polyphenolic compounds encapsulated in RCCM-GTE was found to be 92.550±1.145 μg/g. It is considered that the good antioxidant activity of RCCM-GTE was the comprehensive results of the action of tea polysaccharide-protein conjugate, polyphenolic compounds, cerium and Schiff base chitosan. Investigation showed that a lot of extracts coming from agriculture and food industry contain reactive components of polyphenolic compounds and polysaccharides. It can be effective in protection of human beings from free radical damage if these extracts are directly or after the extraction and purification added to food as natural food antioxidant or they are prepared micospheres reacted with some biopolymers through coordination as a health food. Then the emerging area of research on encapsulating GTE in chitosan cerium resin must have a broad developing prospect.

scholarly journals GREEN TEA EXTRACT IN AN EYELASH GROWTH ENHANCER GEL FORMULATION: STABILITY TEST, EYE IRRITATION TEST, AND HUMAN EYELASH GROWTH ACTIVITY

2017 ◽  
Vol 10 (6) ◽  
pp. 243
Author(s):  
Indra Syahputra Roes Lie ◽  
Joshita Djajadisastra ◽  
Fadlina Chany Saputri
Keyword(s):  
Green Tea ◽  
Chorioallantoic Membrane ◽  
Test Group ◽  
Green Tea Extract ◽  
Stability Test ◽  
Eye Irritation ◽  
Before And After ◽  
Irritation Test ◽  
Tea Extract

Objective: To formulate a green tea extract (GTE), which is often used as a hair growth product, to produce an eyelash gel with good stability, effectiveness, and safety for growing eyelashes.Methods: GTE was formulated into a gel. A stability test was performed at a high temperature (40±2°C), room temperature (25±2°C), low temperature (4±2°C), and a cycling temperature. An in vitro hen’s egg test-chorioallantoic membrane assay was performed to evaluate potential eye irritation. An eyelash growth test was conducted by length measurement using an eyelash ruler before and after 2 mo of application in human volunteers. Results: The GTE gel was stable in storage at high, room, and low temperatures and at cycling temperatures and did not cause eye irritation. Eyelashes grew significantly more in the test group than in the placebo group after 2 mo of application (p<0.05). Conclusion: GTE gel provides a new, safe, and effective option for growing natural eyelashes.

scholarly journals Controlling the Antioxidant Activity of Green Tea Extract through Encapsulation in Chitosan-Citrate Nanogel

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
F. Piran ◽  
Z. Khoshkhoo ◽  
S. E. Hosseini ◽  
M. H. Azizi
Keyword(s):  
Antioxidant Activity ◽  
Particle Size ◽  
Zeta Potential ◽  
Green Tea ◽  
Chitosan Nanoparticles ◽  
Green Tea Extract ◽  
X Ray Diffraction ◽  
Bioactive Ingredients ◽  
Ft Ir ◽  
Tea Extract

Applying bioactive ingredients in the formulation of foods instead of artificial preservatives is problematic because bioactive ingredients are unstable and sensitive to environmental conditions. The present study aimed to control the antioxidant activity of green tea extract (GT) through encapsulating in chitosan nanoparticles (CS-NP). The synthesized nanoparticles were analyzed by using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD). The encapsulation efficiency (EE), particle size, zeta potential, and polydispersity index (PDI) of GT-loaded CS-nanoparticles (CS-NP-GT) were assessed. Based on the results, the particle size and zeta potential related to the ratio of CS to GT of 1 : 0.5 were obtained as 135.43 ± 2.52 nm and 40.40 ± 0.2 mV, respectively. Furthermore, the results of FT-IR and XRD confirmed the validity of encapsulating GT in CS-NP. In addition, the antioxidant activity of GT increased after nanoencapsulation since the IC50 value of CS-NP-GT decreased to 6.13 ± 0.12 μg/ml. Finally, applying these particles for delivering GT polyphenols in foods is regarded as promising.

scholarly journals Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement

2004 ◽  
Vol 80 (6) ◽  
pp. 1558-1564 ◽  
Author(s):  
Susanne M Henning ◽  
Yantao Niu ◽  
Nicolas H Lee ◽  
Gail D Thames ◽  
Rosario R Minutti ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Green Tea ◽  
Black Tea ◽  
Green Tea Extract ◽  
Tea Extract

scholarly journals Effects of Tannase and Ultrasound Treatment on the Bioactive Compounds and Antioxidant Activity of Green Tea Extract

Antioxidants ◽  
2019 ◽  
Vol 8 (9) ◽  
pp. 362 ◽  
Author(s):  
Xiao-Yu Xu ◽  
Jin-Ming Meng ◽  
Qian-Qian Mao ◽  
Ao Shang ◽  
Bang-Yan Li ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Green Tea ◽  
Bioactive Compounds ◽  
Ph Value ◽  
Enzymatic Reaction ◽  
Green Tea Extract ◽  
Ultrasound Treatment ◽  
Ultrasonic Power ◽  
Ultrasonic Time ◽  
Tea Extract

The present study investigated the effects of tannase and ultrasound treatment on the bioactive compounds and antioxidant activity of green tea extract. The single-factor experiments and the response surface methodology were conducted to study the effects of parameters on antioxidant activity of green tea extract. The highest antioxidant activity was found under the optimal condition with the buffer solution pH value of 4.62, ultrasonic temperature of 44.12 °C, ultrasonic time of 12.17 min, tannase concentration of 1 mg/mL, and ultrasonic power of 360 W. Furthermore, phenolic profiles of the extracts were identified and quantified by high-performance liquid chromatography. Overall, it was found that tannase led to an increase in gallic acid and a decrease in epigallocatechin gallate, and ultrasounds could also enhance the efficiency of enzymatic reaction.

Immobilization of green tea extract on polypropylene films to control the antioxidant activity in food packaging

2013 ◽  
Vol 53 (1) ◽  
pp. 522-528 ◽  
Author(s):  
Carol López de Dicastillo ◽  
María del Mar Castro-López ◽  
José Manuel López-Vilariño ◽  
María Victoria González-Rodríguez
Keyword(s):  
Antioxidant Activity ◽  
Green Tea ◽  
Food Packaging ◽  
Green Tea Extract ◽  
Polypropylene Films ◽  
Tea Extract
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