scholarly journals Incidence and location of bone metastases in breast cancer

2019 ◽  
Vol 2 (1) ◽  
pp. 28-31
Author(s):  
Monica Cirstoiu ◽  
Octavian Munteanu ◽  
Oana Bodean ◽  
Florina Paulet ◽  
Bogdan Șerban ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Nuclear Medicine ◽  
Medical Imaging ◽  
Bone Metastases ◽  
Retrospective Analysis ◽  
Functional Imaging ◽  
Imaging Techniques ◽  
X Ray ◽  
Osseous Metastases

AbstractThis report represents an analysis of 19 confirmed cases of breast cancer throughout a period of 14 months (January 2018 - February 2019), in which we assessed the incidence and sites of osseous metastases, in correlation with their histopathologic classification. This retrospective analysis is based on medical imaging techniques (X-ray radiography and nuclear medicine functional imaging).

scholarly journals Osseous metastases and ovarian cancer

2019 ◽  
Vol 2 (1) ◽  
pp. 32-34
Author(s):  
Monica Cirstoiu ◽  
Alexandru Baros ◽  
Florina Paulet ◽  
Delia Gradinaru-Fometescu ◽  
Bogdan Șerban ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Retrospective Study ◽  
Medical Imaging ◽  
Bone Metastases ◽  
Imaging Techniques ◽  
Histological Features ◽  
Osseous Metastases

AbstractThis article analyses a series of 22 confirmed cases of ovarian cancer throughout a period of 14 months (January 2018 - February 2019), in which we assessed the incidence of osseous metastases, in correlation with their histological features. This retrospective study, based on medical imaging techniques, demonstrates that bone metastases are not uncommon in ovarian cancer.

Diagnosis of Bone and Liver Metastases in Breast Cancer Comparing Tumor Markers and Imaging Techniques

1989 ◽  
Vol 4 (2) ◽  
pp. 103-105 ◽  
Author(s):  
P. Zanco ◽  
G. Rota ◽  
V. Sportiello ◽  
N. Borsato ◽  
G. Ferlin
Keyword(s):  
Breast Cancer ◽  
Liver Metastases ◽  
Bone Metastases ◽  
Tumor Markers ◽  
Imaging Techniques ◽  
Hepatic Metastases ◽  
Serum Levels ◽  
Serum Markers ◽  
Surgical Removal ◽  
Rule Out

One hundred and forty-seven patients were examined by bone scintigraphy, ultrasonography and scintigraphic scan of the liver, at different times after surgical removal of a breast cancer, to rule out skeletal and hepatic metastases. At the same time as imaging procedures, serum levels of tumor markers (CEA, TPA and CA 15–3) were determined using radioimmunometric methods. One or more markers were elevated in all 13 patients with hepatic metastases; 9 out of 46 patients with bone metastases had all serum markers normal, with a sensitivity of 80%. Combined assay of the markers proved useful, TPA and CA 15–3 showing the best sensitivity in bone metastases, and all three markers in liver metastases.

Current Status and New Developments in Breast Cancer Diagnosis and Detection

2013 ◽  
Vol 09 (01) ◽  
pp. 21 ◽  
Author(s):  
Demitrios Tzias ◽  
Elizabeth AM O’Flynn ◽  
Steven D Allen ◽  
A Robin M Wilson ◽  
◽  
...  
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Breast Imaging ◽  
Imaging Techniques ◽  
Current Status ◽  
Routine Practice ◽  
Resonance Imaging ◽  
High Frequency Ultrasound ◽  
X Ray

Despite extensive research into new ways of imaging the breast x-ray mammography and breast ultrasound, supplemented where necessary by magnetic resonance imaging, remain the techniques used for the vast majority of breast imaging for screening and the assessment of symptomatic breast problems. Recent advances in these technologies mean that these three techniques are highly effective for both detecting disease and for confirming normality. X-ray based imaging of the breast has been around now for 100 years but it is only in the last 10 years or so that digital technology developments have allowed for major advances in the efficacy of this technique. Digital breast tomosynthesis is currently the most promising technology as it has the potential to both improve detection of breast cancer and greatly reduce the numbers of false positive events. Technological advances in grey scale high frequency ultrasound imaging mean that it is now universally used in both symptomatic diagnosis and breast screening. Newer ultrasound techniques such as 3D imaging, Doppler analyses and elastography add some additional value but so far none of these has achieved their hoped for additional potential. Magnetic resonance imaging is currently the most sensitive imaging technique for the detection and characterisation of breast disease, but its cost remains a barrier to its more widespread use. Nuclear medicine techniques have a role is special circumstances but are yet to show that they should be used in routine practice. There are a large number of potential alternative new imaging techniques for the breast, but, as yet, none of these have shown any significant benefits over the current techniques. Dedicated breast computed tomography has perhaps the best promise but clinically effective breast imaging at present remains in the application and refinement of recent developments in digital mammography, ultrasound and magnetic resonance imaging.

scholarly journals Radiological and nuclear medicine examinations in breastfeeding women. A novel protocol of the Academy of Breastfeeding

2021 ◽  
Vol 4 (3) ◽  
pp. 238-242
Author(s):  
Y.L. Gerashchenko ◽  
◽  
◽  
Keyword(s):  
Nuclear Medicine ◽  
Review Paper ◽  
Imaging Techniques ◽  
Reproductive Technologies ◽  
Lactating Women ◽  
X Ray ◽  
Breast Examination ◽  
The Russian Federation ◽  
Second Period ◽  
And Child Health

This paper discusses a particular time in woman’s life, breastfeeding, that takes from 4 months to 2 years. Mean age of pregnant women increases every year, while reproductive technologies allow for realizing childbearing function in the second period of adulthood. Many diseases those diagnosis requires multiple examinations occur with age. When the mother is forced to stop breastfeeding in view of the need for examination, it is essential for her to get a reasoned rationale and to know the duration of limitations. Unfortunately, no regulations covering the use of modern nuclear medicine and X-ray technologies in breastfeeding women are available in the Russian Federation. Foreign experience may address the existing lack of knowledge. In the future, these data may provide guidance to develop national recommendations. This review paper summarizes the studies on imaging techniques and nuclear medicine procedures in lactating women and limitations of breastfeeding in their use. KEYWORDS: lactation, breastfeeding, breast examination, nuclear medicine, mammologist. FOR CITATION: Gerashchenko Y.L. Radiological and nuclear medicine examinations in breastfeeding women. A novel protocol of the Academy of Breastfeeding. Russian Journal of Woman and Child Health. 2021;4(3):238–242 (in Russ.). DOI: 10.32364/2618-8430-2021-4-3-238-242.

Geomatics for Precise 3D Breast Imaging

2005 ◽  
Vol 4 (1) ◽  
pp. 29-38
Author(s):  
Hilary Alto
Keyword(s):  
Breast Cancer ◽  
Breast Imaging ◽  
Imaging Techniques ◽  
Survey Methods ◽  
Control Object ◽  
Depth Map ◽  
Bundle Adjustment ◽  
X Ray ◽  
Screening Programs ◽  
Direct Linear Transform

Canadian women have a one in nine chance of developing breast cancer during their lifetime. Mammography is the most common imaging technology used for breast cancer detection in its earliest stages through screening programs. Clusters of microcalcifications are primary indicators of breast cancer; the shape, size and number may be used to determine whether they are malignant or benign. However, overlapping images of calcifications on a mammogram hinder the classification of the shape and size of each calcification and a misdiagnosis may occur resulting in either an unnecessary biopsy being performed or a necessary biopsy not being performed. The introduction of 3D imaging techniques such as standard photogrammetry may increase the confidence of the radiologist when making his/her diagnosis. In this paper, traditional analytical photogrammetric techniques for the 3D mathematical reconstruction of microcalcifications are presented. The techniques are applied to a specially designed and constructed x-ray transparent Plexiglas phantom (control object). The phantom was embedded with 1.0 mm x-ray opaque lead pellets configured to represent overlapping microcalcifications. Control points on the phantom were determined by standard survey methods and hand measurements. X-ray films were obtained using a LORAD M-III mammography machine. The photogrammetric techniques of relative and absolute orientation were applied to the 2D mammographic films to analytically generate a 3D depth map with an overall accuracy of 0.6 mm. A Bundle Adjustment and the Direct Linear Transform were used to confirm the results.

scholarly journals Bone density as a marker for local response to radiotherapy of spinal bone metastases in women with breast cancer: a retrospective analysis

2015 ◽  
Vol 10 (1) ◽  
pp. 62 ◽  
Author(s):  
Robert Foerster ◽  
Christian Eisele ◽  
Thomas Bruckner ◽  
Tilman Bostel ◽  
Ingmar Schlampp ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Density ◽  
Bone Metastases ◽  
Retrospective Analysis ◽  
Local Response ◽  
Spinal Bone Metastases

scholarly journals Functionalized Lanthanide Oxide Nanoparticles for Tumor Targeting, Medical Imaging, and Therapy

Pharmaceutics ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1890
Author(s):  
Mohammad Yaseen Ahmad ◽  
Huan Yue ◽  
Tirusew Tegafaw ◽  
Shuwen Liu ◽  
Son Long Ho ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Contrast Agents ◽  
Tumor Targeting ◽  
Imaging Techniques ◽  
Tumor Therapy ◽  
Mri Contrast Agents ◽  
Mri Contrast ◽  
Lanthanide Oxide ◽  
X Ray

Recent progress in functionalized lanthanide oxide (Ln2O3) nanoparticles for tumor targeting, medical imaging, and therapy is reviewed. Among the medical imaging techniques, magnetic resonance imaging (MRI) is an important noninvasive imaging tool for tumor diagnosis due to its high spatial resolution and excellent imaging contrast, especially when contrast agents are used. However, commercially available low-molecular-weight MRI contrast agents exhibit several shortcomings, such as nonspecificity for the tissue of interest and rapid excretion in vivo. Recently, nanoparticle-based MRI contrast agents have become a hot research topic in biomedical imaging due to their high performance, easy surface functionalization, and low toxicity. Among them, functionalized Ln2O3 nanoparticles are applicable as MRI contrast agents for tumor-targeting and nontumor-targeting imaging and image-guided tumor therapy. Primarily, Gd2O3 nanoparticles have been intensively investigated as tumor-targeting T1 MRI contrast agents. T2 MRI is also possible due to the appreciable paramagnetic moments of Ln2O3 nanoparticles (Ln = Dy, Ho, and Tb) at room temperature arising from the nonzero orbital motion of 4f electrons. In addition, Ln2O3 nanoparticles are eligible as X-ray computed tomography contrast agents because of their high X-ray attenuation power. Since nanoparticle toxicity is of great concern, recent toxicity studies on Ln2O3 nanoparticles are also discussed.

scholarly journals Impact of surgery on survival in breast cancer with bone metastases only: a SEER database retrospective analysis

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Pai Peng ◽  
Jiang-Yuan Chen ◽  
Yun-Tao Han ◽  
Xin Chen ◽  
Hong-Yuan Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Metastasis ◽  
Bone Metastases ◽  
Survival Time ◽  
Retrospective Analysis ◽  
Median Survival ◽  
Median Survival Time ◽  
Seer Database ◽  
Primary Surgery ◽  
Surgical Group

Abstract Background It was controversial to operate on the primary site of breast cancer (BC) with bone metastasis only. We investigated the impact of surgery on BC patients with bone metastases via a SEER database retrospective analysis. Methods A total of 2917 BC cases with bone metastasis, first diagnosed between 2010 and 2015 in the Surveillance, Epidemiology, and Results Database (SEER) of National Cancer Institute were selected. We assessed the effect of different surgical procedures on survival and prognosis. Results Compared with the non-surgical group, the primary tumor surgical group showed longer median survival time (χ2 = 146.023, P < 0.001), and the breast-conserving subgroup showed the highest median survival time of 70 months (χ2 = 157.117, P < 0.001). Compared with the non-surgery group, the median overall survival (OS) of primary surgery group was longer (HR = 0.525, 95%CI = 0.467–0.590, P < 0.001), and the breast-conserving subgroup showed the longest median operative OS (HR = 0.394, 95%CI = 0.325–0.478, P < 0.001). Conclusion This study showed that primary surgery could improve the median survival time and OS of BC patients with bone metastasis. Moreover, under the condition of low tumor burden, breast conserving surgery was a better choice.

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