The Marquis de Sade and the Power of Eroticism

2019 ◽  
Author(s):  
Hasti Pourriahi
Keyword(s):  
Social Justice ◽  
Catholic Church ◽  
Psychological Effects ◽  
Marquis De Sade ◽  
Social Diversity ◽  
Relevant Today ◽  
A Site ◽  
Sexual Repression ◽  
Insight Into ◽  
Important Site

With increasing levels of consensus that sexuality is an important site of social diversity, we are gaining more insight into the detrimental social and psychological effects of sexual repression. Yet, sex continues to be a site shaped by taboo. Personal liberation seems to call for taboobreakers. With that, I ask whether there is anything liberating to learn from the life and work of one of the most notorious violators of sexual and other social mores. I consider the case of the Marquis de Sade (1740-1814). His writing and libertine philosophies were critical of the Catholic Church at a time when dissent was rising. But what made him so radical? Was he merely perceived as a threat by those wanting to protect their power? Or is there something more radically threatening and potentially liberating in his libertinism? What is it about the power of eroticism that makes it so threatening? Can this power be utilized as a tool for empowerment in the context of contemporary social justice struggles, or is it simply violence? I examine how de Sade’s work contributed to a radical counterargument against dominant sexually repressive mores. I conclude with critical remarks and provocative questions about the legacy of his work, which is no less relevant today than it has ever been

scholarly journals Development of Fragility Curves for Piping and Slope Stability of River Levees

Water ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 738
Author(s):  
Nicola Rossi ◽  
Mario Bačić ◽  
Meho Saša Kovačević ◽  
Lovorka Librić
Keyword(s):  
Slope Stability ◽  
Fragility Curves ◽  
Safety Margin ◽  
Water Levels ◽  
Flood Event ◽  
Soil Parameters ◽  
Design Code ◽  
A Site ◽  
Insight Into

The design code Eurocode 7 relies on semi-probabilistic calculation procedures, through utilization of the soil parameters obtained by in situ and laboratory tests, or by the means of transformation models. To reach a prescribed safety margin, the inherent soil parameter variability is accounted for through the application of partial factors to either soil parameters directly or to the resistance. However, considering several sources of geotechnical uncertainty, including the inherent soil variability, measurement error and transformation uncertainty, full probabilistic analyses should be implemented to directly consider the site-specific variability. This paper presents the procedure of developing fragility curves for levee slope stability and piping as failure mechanisms that lead to larger breaches, where a direct influence of the flood event intensity on the probability of failure is calculated. A range of fragility curve sets is presented, considering the variability of levee material properties and varying durations of the flood event, thus providing crucial insight into the vulnerability of the levee exposed to rising water levels. The procedure is applied to the River Drava levee, a site which has shown a continuous trend of increased water levels in recent years.

scholarly journals “IF YOU DON’T KNOW ME BY NOW…”

2021 ◽  
pp. 1-28
Author(s):  
Ellen M. Whitehead ◽  
Allan Farrell ◽  
Jenifer L. Bratter
Keyword(s):  
Race And Ethnicity ◽  
Mate Selection ◽  
Racial Identities ◽  
Hispanic Origin ◽  
Socially Constructed ◽  
Attitudinal Factors ◽  
A Site ◽  
Intimate Partnerships ◽  
College Educated ◽  
Insight Into

ABSTRACT The racial composition of couples is a salient indicator of race’s impact on mate selection, but how well do those in intimate partnerships know the racial identities of their partners? While prior research has revealed that an individual’s race may be perceived differently than how they identify, most of what is known comes from brief interactions, with less information on established relationships. This study examines whether discrepancies in the reports of a person’s race or ethnicity can be identified even within intimate relationships, as well as which relational, social, and attitudinal factors are predictive of divergent or concordant reports. We draw on the Fragile Families and Child Wellbeing Study (n=3467), a U.S.-based dataset that uniquely provides both the father’s self-reported race and Hispanic origin and the mother’s report of the father’s race and ethnicity. We compare reports of the father’s race/Hispanic origin from both parents to assess the extent of mismatch, and we distinguish between whether mothers view the father’s race as similar to or different from her own. We find roughly 14% of mothers provide a race and Hispanic origin that is inconsistent with the father’s report, with a large share reflecting differences in the self-identified and perceived race of fathers who are reported as Hispanic. Among mismatched reports, mothers are more likely to report a race/ethnicity for the father that matches her own, depressing the number reporting interracial unions. Perceptions of racial homogamy are especially likely when mothers view racial sameness as important to marriage. Further, mismatches are more common in the midst of weak relational ties (i.e. non-marital relationships) and are less common when both parents are college-educated. These findings reveal that intimate unions are a site where race is socially constructed and provide insight into how norms of endogamy manifest within formed relationships.

scholarly journals Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jiqing Du ◽  
Marie-Kristin von Wrisberg ◽  
Burak Gulen ◽  
Matthias Stahl ◽  
Christian Pett ◽  
...  
Keyword(s):  
Legionella Pneumophila ◽  
Adenosine Monophosphate ◽  
Vesicular Trafficking ◽  
Bacterial Protein ◽  
Post Translational Modification ◽  
Allosteric Control ◽  
Rab Protein ◽  
Biochemical Characterisation ◽  
A Site ◽  
Insight Into

AbstractLegionella pneumophila infects eukaryotic cells by forming a replicative organelle – the Legionella containing vacuole. During this process, the bacterial protein DrrA/SidM is secreted and manipulates the activity and post-translational modification (PTM) states of the vesicular trafficking regulator Rab1. As a result, Rab1 is modified with an adenosine monophosphate (AMP), and this process is referred to as AMPylation. Here, we use a chemical approach to stabilise low-affinity Rab:DrrA complexes in a site-specific manner to gain insight into the molecular basis of the interaction between the Rab protein and the AMPylation domain of DrrA. The crystal structure of the Rab:DrrA complex reveals a previously unknown non-conventional Rab-binding site (NC-RBS). Biochemical characterisation demonstrates allosteric stimulation of the AMPylation activity of DrrA via Rab binding to the NC-RBS. We speculate that allosteric control of DrrA could in principle prevent random and potentially cytotoxic AMPylation in the host, thereby perhaps ensuring efficient infection by Legionella.

scholarly journals Structure of a canonical RNase YoeB bound to the ribosome

2014 ◽  
Vol 70 (a1) ◽  
pp. C207-C207
Author(s):  
Yun Chen ◽  
Shu Feng ◽  
Katsuhiko Kamada ◽  
Han Wang ◽  
Kai Tang ◽  
...  
Keyword(s):  
Specific Activity ◽  
Base Catalysis ◽  
Mass Spectrometry Data ◽  
Catalytic Core ◽  
General Base ◽  
Rna Hydrolysis ◽  
70S Ribosome ◽  
A Site ◽  
Insight Into

As a typical endoribonuclease, YoeB mediates cellular adaptation in diverse bacteria by degrading mRNAs on its activation. Although the catalytic core of YoeB is thought to be identical to well-studied nucleases, this enzyme specifically targets mRNA substrates that are associated with ribosomes in vivo. However, the molecular mechanism of mRNA recognition and cleavage by YoeB, and the requirement of ribosome for its optimal activity, largely remain elusive. Here, we report the structure of YoeB bound to 70S ribosome in pre-cleavage state, revealing that both the 30S and 50S subunits participate in YoeB binding. The mRNA is recognized by the catalytic core of YoeB, of which the general base/acid (Glu46/His83) are within hydrogen-bonding distance to their reaction atoms, demonstrating an active conformation of YoeB on ribosome. Also, the mRNA orientation involves the universally conserved A1493 and G530 of 16S rRNA. In addition, mass spectrometry data indicated that YoeB cleaves mRNA following the second position at the A-site codon, resulting in a final product with a 3'–phosphate at the newly formed 3' end. Our results demonstrate a classical acid-base catalysis for YoeB-mediated RNA hydrolysis and provide insight into how the ribosome is essential for its specific activity.

Revisiting Trauma: Wounds Seen and Unseen in Canadian and Indian Prison Narratives

2021 ◽  
Vol 2 (3) ◽  
pp. 16-30
Author(s):  
Lavanya Dalal
Keyword(s):  
Psychological Trauma ◽  
Prison System ◽  
Psychological Effects ◽  
Trauma Studies ◽  
Prison Narratives ◽  
The Past ◽  
A Site

Trauma Studies and Prison Narratives have emerged over the past few decades as the most significant fields in the humanities. There has been a significant discussion regarding the psychological effects of incarceration; however, literature examining prison as a site of trauma is unusual. Focusing on Iftikhar Gilani's My Days in Prison (2005) and Yvonne Johnson and Rudy Wiebe's Stolen Life: The Journey of a Cree Woman (1998), the article analyzes how prison narratives represent prison as a violent space that inflicts trauma in its characters. These prison narratives represent Yvonne Johnson, the prisoner in Stolen Life, and Gilani as victims of acute psychological trauma faced due to the sheer viciousness of the prison system. The article also concentrates on how the prison experience is both similar and different in Canada and India.    

Nummulites Fayumensis N. Sp. and Nummulites Tenuissimus N. Sp. from Munquar El-rayan, Fayum, Egypt

2018 ◽  
Vol 48 (1) ◽  
pp. 17-28 ◽  
Author(s):  
Safia Al Menoufy ◽  
Mohamed Boukhary
Keyword(s):  
New Species ◽  
Foraminiferal Assemblage ◽  
Shallow Marine ◽  
Marine Facies ◽  
Benthic Foraminiferal Assemblage ◽  
Insight Into ◽  
Important Site

Abstract Nummulites fayumensis n. sp. and Nummulites tenuissimus n. sp. are described from the Munqar El-Rayan Section, Fayum, Egypt. Nummulites tenuissimus belongs to the N. partschi group, while N. fayumensis belongs to the N. gizehensis group, based on diameter and protoconch sizes, septal shape and granulations. Both new species are of Lutetian age, assigned to SBZ14/15, and encountered in shallow-marine facies. Wadi El-Rayan is an important site for vertebrate fossils in Egypt and the abundant larger benthic foraminiferal assemblage provides insight into paleoenvironmental parameters associated with the deposition of Eocene-age rock units of the Munqar El-Rayan Section.

scholarly journals Ks. Andrzej Dziełak „Gdyby nie kardynał kominek, nie byłoby Jana Pawła II”. Wspomnienie o Bolesławie Kominku i Orędziu biskupów Polskich do biskupów niemieckich

2011 ◽  
Vol 1 ◽  
pp. 195-212
Author(s):  
Piotr Sroka
Keyword(s):  
Catholic Church ◽  
Great Part ◽  
Scientific Conference ◽  
Catholic Clergy ◽  
Communist State ◽  
Pastoral Letter ◽  
Communist Government ◽  
Insight Into ◽  
The Catholic Church

An account given by Rev. Andrzej Dziełak is one of over a dozen such narratives written down for a scientific conference “Cardinal Kominek – a forerunner of the Polish-German reconciliation” which was organized by The Memory and Future Institute (Wrocław, 4th December 2008). These conference documents give us insight into circumstances and consequences of the Polish bishops addressing the German bishops. In some parts, these documents are focused in the narrative of Rev. Andrzej Dziełak, who in 1965 was a clerical student in the Higher Seminary in Wrocław. For contemporary clerics Cardinal Kominek was an indisputable authority, both moral and intellectual. Every Saturday during a seminary meeting he would share with them his observations on the situation of the Catholic Church in those days in Poland and abroad, and on complex relations with the communist state. Still, the Pastoral Letter of the Polish bishops to the German bishops turned out to be a huge surprise to the Catholic clergy of Wrocław, especially since at the beginning they did not have the text of the document at their disposal. Rev. Dziełak admits that at the beginning the message conveyed in the Letter was received with reluctance by a great part of the congregation. This was due to the recent war and a successful propaganda of the communist government. However, right from the beginning, clerics had no doubts as to the identity of the author of the groundbreaking document – they knew that it was prepared by a bishop of Wrocław who was the most knowledgeable person in the Episcopate regarding German issues.

scholarly journals Acknowledging the relevance of empathy in clinical legal education. Some proposals from the experience of the University of Brescia (IT) and Valencia (ESP)

2018 ◽  
Vol 25 (2) ◽  
pp. 218
Author(s):  
Andrés Gascón-Cuenca ◽  
Carla Ghitti ◽  
Francesca Malzani
Keyword(s):  
Social Justice ◽  
Clinical Education ◽  
Clinical Training ◽  
Legal Education ◽  
Social Diversity ◽  
The People ◽  
Training Plan ◽  
New Challenges ◽  
The University ◽  
Great Development

Legal Clinical Education is experiencing a great development in the Spanish and the Italian university context. Nevertheless, it comes with new challenges that professors have not faced until now: students working in the field with people in situations of vulnerability or in complex realities. Given that one of the major goals of CLE is the preparation not only of professionals for the practice of law, but also people concerned about social justice and social diversity, this piece of research looks into the significance of working with students about the key role that empathy plays in the development of their relation with the people they assist. Moreover, we will suggest some activities to be introduced in the clinical training plan with this purpose, and lastly, we will construct some final thoughts about this research and the feedback we obtain from our clinical colleagues.

scholarly journals The Irish Céilí: A Site for Constructing, Experiencing, and Negotiating a Sense of Community and Identity

2011 ◽  
Vol 29 (1) ◽  
pp. 43-60 ◽  
Author(s):  
Catherine E. Foley
Keyword(s):  
Nineteenth Century ◽  
Twentieth Century ◽  
Sense Of Community ◽  
Late Nineteenth Century ◽  
Social Dance ◽  
Late Nineteenth ◽  
A Site ◽  
Changing Role ◽  
Important Site

For over a hundred years the Irish céilí, as an ‘invented’ social dance event and mode of interaction, has played a significant and changing role. This paper examines the invention of this Irish dance event and how it has developed in Ireland throughout the twentieth century. From the Gaelic League's cultural nationalist, ideological agenda of the late nineteenth century, for a culturally unified Ireland, to the manifestation of a new cultural confidence in Ireland, from the 1970s, this paper explores how the céilí has provided an important site for the construction, experiencing and negotiation of different senses of community and identity.

scholarly journals "Unaccomodated Man": Dismodernism and Disability Justice in King Lear

2018 ◽  
Vol 38 (4) ◽  
Author(s):  
Christine M. Gottlieb
Keyword(s):  
Social Justice ◽  
Early Modern ◽  
Disability Studies ◽  
Theoretical Concept ◽  
King Lear ◽  
Significant Disability ◽  
Human Animal ◽  
Important Site

King Lear's exploration of what it means to be human has significant Disability Studies implications that have not yet been examined. Through the course of the play, Lear gains awareness of interdependence, bodily vulnerability, and human-animal kinship, and his new worldview unsettles the shared ground of ableism and anthropocentrism. Analyzing three of Lear's significant speeches, I argue that King Lear's exploration of what it means to be human anticipates Lennard Davis's recent theoretical concept, dismodernism. Both Lear and Gloucester express concern for Poor Tom in ways that link disability to community and social justice. Through considering King Lear in relation to early modern contexts and current Disability Studies theory and activism, I argue that the play is an important site for developing a socially conscious Shakespearean Disability Studies.

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