The Relationship between Chronic Rhinosinusitis and Metabolic Syndrome

2017 ◽  
Vol 31 (4) ◽  
pp. 222-227 ◽  
Author(s):  
Eun Jung Lee ◽  
Hye Jin Hwang ◽  
Chan Min Jung ◽  
Min Ki Kim ◽  
Min Seok Kang ◽  
...  

Background This study aimed to investigate the correlation between metabolic syndrome and chronic rhinosinusitis (CRS), with related risk factors for CRS according to data from the Korean National Health and Nutrition Examination Survey (KNHANES). Methods The KNHANES surveyed individuals >19 years of age from January 2010 to December 2011. CRS encompassed “symptom-based CRS” as defined by the European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Metabolic syndrome was diagnosed according to the American Heart Association/National Heart Lung and Blood Institute criteria. A χ2 analysis, univariate analysis, and multivariate analysis were conducted. Results A total of 12,015 individuals were analyzed in this study. The prevalence of CRS in the patients with metabolic syndrome (high triglyceride level, reduced high-density lipoprotein level, and elevated blood pressure) was significantly higher than that in patients without metabolic syndrome (14.15 versus 10.16%) (p < 0.05). Allergic rhinitis was the only significant risk factor for CRS found to be associated with metabolic syndrome (p < 0.05). Conclusion CRS was more prevalent in patients with metabolic syndrome, especially those with allergic rhinitis, than in patients without metabolic syndrome. Accordingly, CRS should be considered in patients with metabolic syndrome and allergic rhinitis.

2020 ◽  
Author(s):  
Shasha Yu ◽  
Xiaofan Guo ◽  
GuangXiao Li ◽  
Hongmei Yang ◽  
Liqiang Zheng ◽  
...  

Abstract Background To evaluate the possible predictive effect of metabolic syndrome (MetS) and its components on cardiovascular disease (CVD) in a longitudinal analysis according to different criteria of MetS among rural Chinese elderly. Method A population-based sample of 2486 rural elderly Chinese residents aged ≥ 60 years at baseline were followed up from 2012–2013 to 2015–2017. CVD included stroke, coronary heart disease (CHD) diagnosed by clinicians were self-reported and were confirmed by medical records. MetS was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) and the international Diabetes Federation (IDF) criterion respectively. Result Hazard ratio adjusting for CHD, Stroke and CVD in those with MetS using NCEP ATP III criteria in female were 1.27 (95%CI 0.73, 2.21), 1.54 (95%CI 0.99, 2.40) and 1.45 (95%CI 1.00, 2.10); 1.33 (95%CI 0.77, 2.32), 1.44 (95%CI 0.92, 2.25) and 1.36 (95%CI 0.94, 1.97) with the AHA/NHLBI criteria; and 1.10 (95%CI 0.89,1.36), 1.62 (95%CI 1.03, 2.55) and 1.36 (95%CI 0.93, 1.97) with IDF criteria. Besides, abdominal obesity using the AHA/NHLBI criteria was significantly associated with the incidence of stroke (HR: 1.60; 95%CI 1.01, 2.52). However, among rural male elderly, neither MetS nor its components were capable of predicting newly onset CVD. Conclusion MetS is significantly associated with high incidence of CVD among rural female elderly only, and the incidence of CVD was evident only when MetS was defined using NCEP ATP III criterion. In order to reduce CVD among elderly in rural China, effective strategies to prevent, diagnose, and treating MetS should be made in time, especially among female.


2021 ◽  
Author(s):  
Hye Jeong Kim ◽  
Sang Joon Park ◽  
Hyeong Kyu Park ◽  
Dong Won Byun ◽  
Kyoil Suh ◽  
...  

Objective Recent studies have reported that thyroid hormone levels are associated with metabolic syndrome (MetS) even in euthyroid subjects. However, the association between thyroid autoimmunity and MetS is uncertain. We aimed to investigate the relationship between thyroid autoimmunity and MetS in a large cohort study of euthyroid subjects. Methods A total of 4,775 participants aged ≥19 years from the Korea National Health and Nutrition Examination Survey VI (2013-2015) with anti-thyroid peroxidase antibody (TPOAb) results and normal thyroid functions were included in this study. Subjects were grouped according to thyroid autoimmunity (positivity of TPOAb). We estimated the odds ratios (ORs) for MetS according to TPOAb positivity using logistic regression models, adjusted for potential confounders. Results Among the study subjects, 25% (n=1,206) were diagnosed with MetS. Subjects with MetS showed higher median TPOAb levels (6.3 vs 6.8 IU/mL, p<0.001) and higher positivity of TPOAb (5 vs 7%, p=0.002) than those without MetS. There was a significant difference in prevalence of MetS depending on the TPOAb positivity (25% vs 33%, p=0.002). Subjects with TPOAb positive had a significantly greater risk of abdominal obesity [OR 1.675, 95% confidence interval (CI) 1.302-2.154, p<0.001], low high-density lipoprotein cholesterol (OR 1.603, 95% CI 1.244-2.066, p<0.001) and elevated blood pressure (OR 1.418, 95% CI 1.099-1.829, p=0.007), as compared to those with TPOAb negative. Positivity of TPOAb was a significant risk factor for MetS even after adjusting for confounding variables including age, sex, household income, education, smoking, alcohol consumption, walking activity, thyroid-stimulating hormone and free thyroxine (OR 1.389, 95% CI 1.048-1.841, p=0.022). Conclusion In euthyroid subjects, thyroid autoimmunity is associated with MetS. Further large longitudinal studies are needed to clarify causality.


2017 ◽  
Vol 7 (2) ◽  
pp. 100-104
Author(s):  
M. Rożniata ◽  
K. Zujko ◽  
M.E. Zujko

The term metabolic syndrome (MetS) defines the cooccurrence of the related risk factors of metabolic origin that promote the development of cardiovascular diseases with atherosclerotic background and type 2 diabetes. The diagnostic criteria of MetS have undergone modifications for years. Until now no clear definition of MetS has been established. The latest diagnostic criteria of MetS published in 2009 by a group of IDF (International Diabetes Federation) and AHA/NHLBI (American Heart Association/ National Heart, Lung and Blood Institute) experts discern three out of five risk factors: abdominal obesity (taking into consideration population differences), elevated level of triglycerides, reduced HDL cholesterol, hypertension and fasting hyperglycemia. Genetic predispositions and environmental factors, such as lack of physical activity and improper diet are considered to be responsible for MetS development. Therefore, prevention and treatment of MetS should be based first of all on a change in modifiable lifestyle factors, among which proper diet is of essential importance.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shasha Yu ◽  
Xiaofan Guo ◽  
GuangXiao Li ◽  
Hongmei Yang ◽  
Liqiang Zheng ◽  
...  

Abstract Background This study aimed to estimate whether metabolic syndrome (MetS) and its components could be used to predict cardiovascular disease (CVD) in a longitudinal analysis in a rural elderly Chinese population. Method At baseline during 2012–2013, a total of 2486 elderly from rural Chinese were enrolled and were followed up during 2015–2017. Stroke and coronary heart disease (CHD) were included in CVD and were diagnosed by clinicians. The National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III), the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) and the International Diabetes Federation (IDF) criteria were used to define MetS separately. Result Hazard ratios adjusting for CHD, stroke and CVD in those with MetS using the NCEP ATP III criteria in females were 1.27 (95 % CI 0.73, 2.21), 1.54 (95 % CI 0.99, 2.40) and 1.45 (95 % CI 1.00, 2.10), respectively; 1.33 (95 % CI 0.77, 2.32), 1.44 (95 % CI 0.92, 2.25) and 1.36 (95 % CI 0.94, 1.97), respectively, with the AHA/NHLBI criteria; and 1.10 (95 % CI 0.89,1.36), 1.62 (95 % CI 1.03, 2.55) and 1.36 (95 % CI 0.93, 1.97), respectively, with the IDF criteria. Additionally, abdominal obesity using the AHA/NHLBI criteria was significantly associated with the incidence of stroke (HR: 1.60; 95 % CI 1.01, 2.52). However, among rural elderly males, neither MetS nor its components predicted new-onset CVD. Conclusions MetS is correlated with high incidence of CVD among rural elderly female, and only using the NCEP ATP III criteria to define MetS could make the incidence of CVD obvious difference. In order to reduce rural elderly CVD, effective measures to prevent, diagnose, and treat MetS should be enacted in a timely manner, especially among females.


2017 ◽  
Vol 47 (4) ◽  
pp. 543-552
Author(s):  
Roberto Wagner Júnior Freire de Freitas ◽  
Márcio Flávio Moura de Araújo ◽  
Maria Wendiane Gueiros Gaspar ◽  
José Cláudio Garcia Lira Neto ◽  
Ana Maria Parente Garcia Alencar ◽  
...  

Purpose This paper aims to compare the prevalence of metabolic syndrome (MetS) on the basis of three criteria. The diagnostic criteria adopted were those of the International Diabetes Federation, the National Cholesterol Education Program – Adult Treatment Panel III and the American Heart Association/National Heart, Lung and Blood Institute.. Design/methodology/approach A transversal study was undertaken with 691 university students in Fortaleza, Brazil, in 2011-2013. Findings The prevalence of MetS varied considerably according to the criteria used, it being 4.1 per cent for the IDF, 0.7 per cent for the NCEP ATPIII and 1.7 per cent for the revised NCEP ATPIII. The criteria of the IDF presented reasonable agreement in relation to the NCEP ATP III (0.294) and revised NCEP ATP III (0.334). Moderate agreement was found between the NCEP ATPIII/revised NCEP ATPIII. Originality/value There is a need for a universal diagnostic criterion for MetS to obtain uniform and more reliable data for the elaboration of public health policies.


2016 ◽  
Vol 32 (3) ◽  
pp. 587-594 ◽  
Author(s):  
Meghan K. Edwards ◽  
Paul D. Loprinzi

Purpose: Limited research has evaluated the independent and additive associations of moderate-to-vigorous physical activity (MVPA), sedentary behavior (SB), and cardiorespiratory fitness (CRF) with metabolic syndrome, which was the purpose of this study. Design: Cross-sectional. Setting: National Health and Nutrition Examination Survey 2003 to 2004. Sample: Three hundred seven adults aged 20 to 49 years. Measures: Moderate-to-vigorous physical activity and SB were assessed via accelerometer, whereas CRF was assessed via submaximal treadmill testing. Metabolic syndrome was assessed via the American Heart Association/National Heart, Lung, and Blood Institute guidelines. Analysis: Multivariable logistic regression. Results: A 10 min/d increase in MVPA was associated with a 45% reduced odds of metabolic syndrome (odds ratio [OR] = 0.55, 95% confidence interval [CI] = 0.40-0.76, P = .001), and a 10 mL/kg/min increase in CRF was associated with a 43% reduced odds of having metabolic syndrome (OR = 0.57, 95% CI = 0.37-0.87, P = .013). Additionally, a statistically significant combined association of MVPA, SB, and CRF with metabolic syndrome was present; individuals who had below-median SB and above-median MVPA and CRF had an 88% reduced odds of metabolic syndrome (OR = 0.12, 95% CI = 0.03-0.48, P = .005) when compared to those who had below-median MVPA and CRF and above-median SB. Conclusion: When considering MVPA, SB, and CRF, MVPA and CRF were both independently associated with metabolic syndrome (SB was not) among this young adult population and there was also evidence to support a combined association of all 3 parameters on metabolic syndrome.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
J.R. Azanza ◽  
M. Bernardo ◽  
L. Rojo ◽  
J. Rejas-Gutiérrez ◽  
F. Mesa

Aims:The metabolic syndrome MS (visceral obesity, dyslipidaemia, hyperglycaemia, and hypertension), has become one of the major public-health challenges worldwide. Patients with schizophrenia are more likely to suffer from MS that the general population. We have analyzed the prevalence of MS in Spanish patients with schizophrenia and overweight.Methods:The CRESSOB study is a 12-month, prospective, naturalistic study including 110 community mental health clinics selected at random. Each site enrolled four consecutive patients with diagnosis of schizophrenia, according to DSM-IV TR criteria, and overweight (BMI > 25 Kg/m2). to assess the prevalence of MS we have analyzed the baseline results of the CRESSOB study. the National Cholesterol Educational Program (NCEP-ATPIII), the International Diabetes Federation (IDF) and the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) definitions were used to established the presence of MS.Results:A total of 391 patients were enrolled on the study (mean age 40.5 years, 63.8% men). 75.9% of the patients did not meet criteria for remission, using the selected PANSS items. Mean GAF score was 52.7 (SD 15.4). Using the different criteria, 59.0% of males and 58.3% of females fulfilled the NCEP-ATPIII criteria, 71.1% of males and 65.8% of females fulfilled the IDF criteria and 70.1% of males and 65.1% of females fulfilled the AHA/NHLBI criteria.Conclusions:The MS is highly prevalent in Spanish patients with schizophrenia and overweight. Given the metabolic syndrome is an important risk factor for cardiovascular disease, these patients should receive appropriate clinical monitoring for this syndrome.


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