scholarly journals De periodontitis agresiva a periodontitis: modificaciones en su clasificación y tratamiento a través del reporte de caso

UVserva ◽  
2021 ◽  
pp. 93-104
Author(s):  
Michelle Rustrián-Campillo ◽  
Miguel Hazael Russell-Hernández ◽  
Miguel Eric García-Rivera ◽  
María Gabriela Nachón-García
Keyword(s):  
Periodontal Disease ◽  
Familial Aggregation ◽  
Bone Destruction ◽  
Stage Iv ◽  
Oral Pathology ◽  
Aggressive Periodontitis ◽  
Comprehensive Treatment ◽  
Radiographic Findings ◽  
Palabras Clave

Introducción: En la Clasificación de las Enfermedades y Afecciones Periodontales y Periimplantarias de 2018, la periodontitis agresiva (PA), se considera como enfermedad periodontal estadio IV, grado C, patrón incisivo molar. Consiste en una patología bucal que ocurre en individuos aparentemente sanos, con periodontitis, rápida pérdida de inserción, destrucción ósea y agregación familiar. A lo largo de décadas esta enfermedad ha sufrido cambios en su definición y clasificación. Objetivo: Describir por medio del caso clínico las características y tratamiento de la periodontitis agresiva en la clasificación periodontal más reciente. Reporte de caso: hombre de 49 años, diagnosticado con periodontitis agresiva generalizada (PAG), con base en los hallazgos clínicos y radiográficos. Se realizó un tratamiento integral, con seguimiento de tres años, observando recidiva de la enfermedad. Conclusión: la implementación del uso de indicadores séricos y exámenes microbiológicos podría mejorar la clasificación actual y facilitar el diagnóstico y manejo del paciente. Palabras clave: Periodontitis agresiva; enfermedad periodontal estadio IV-grado C; clasificación periodontal; diagnóstico periodontal. From aggressive periodontitis to periodontitis: modifications in its classification and treatment through the case reportIntroduction: In the Classification of Periodontal and Peri-implant Diseases and Conditions of 2018, aggressive periodontitis (AP) is considered stage IV, grade C periodontal disease, molar incisor pattern. It consists of an oral pathology that occurs in apparently healthy individuals, with periodontitis, the rapid loss of attachment, bone destruction, and familial aggregation. Over the decades, this disease has changed its definition and classification. Objective: To describe aggressive periodontitis's characteristics and treatment in the most recent periodontal through the clinical case category. Case report: 49-year-old man, diagnosed with generalized aggressive periodontitis (PAG), based on clinical and radiographic findings. Comprehensive treatment was carried out, with a three-year follow-up, observing recurrence of the disease. Conclusion: The implementation of serum indicators and microbiological examinations could improve the current classification and facilitate the patient's diagnosis and management.Keywords: aggressive periodontitis, stage IV-grade C periodontal disease, periodontal classification, periodontal diagnosis. 

scholarly journals AGGRESSIVE PERIODONTITIS: 18 MONTHS FOLLOW UP - A CASE REPORT

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dagar Mona ◽  
Sharma Anamika
Keyword(s):  
Surgical Intervention ◽  
Periodontal Diseases ◽  
International Workshop ◽  
Aggressive Periodontitis ◽  
Scaling And Root Planing ◽  
Disease Treatment ◽  
Radiographic Findings ◽  
Hereditary Factors

The diagnosis "Aggressive Periodontitis", defined by the International Workshop for Classification of Periodontal Diseases and Conditions in 1999, refers to the multifactorial, severe, and rapidly progressive form of Periodontitis, which primarily – but not exclusively – affects younger patients. Aggressive periodontitis have localized and generalized forms. It is currently believed that combination of bacteriologic, immunologic and hereditary factors are of major importance in the etiology of this disease. The case was of a 20 year old female and her clinical and radiographic findings were typical for generalized Aggressive Periodontitis. Treatment consisted of thorough scaling and root planing along with administration of tetracycline250 mg every six hours for three weeks, followed by surgical intervention. Keywords: Aggressive periodontitis, multifactorial disease, treatment

scholarly journals Comprehensive periodontal treatment in generalized stage iv, grade c periodontitis: a clinical case report

2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Sahar Chokami Rafiei ◽  
Jowel Makdisi ◽  
Samira Mohamad Mirzapour
Keyword(s):  
Case Report ◽  
Bone Destruction ◽  
Stage Iv ◽  
Aggressive Periodontitis ◽  
Periodontal Treatment ◽  
Successful Outcome ◽  
Scaling And Root Planing ◽  
Implant Placement ◽  
Root Planing ◽  
The One

Generalized stage IV, grade C periodontitis results in rapid bone destruction in the periodontium and can lead to early tooth loss. Scaling and root planing (SRP) complemented by systemic antibiotics, access surgery, regenerative techniques and implant placement are among the treatments used for patients with this condition. The aim of this article is to report a comprehensive periodontal treatment in a 23-year-old male who was referred to the periodontology department due to complaints of tooth mobility and gum infections diagnosed with generalized stage IV, grade C periodontitis according to the clinical, systemic, and family history features observed. Thorough non-surgical periodontal treatment consisting of scaling and root planing was provided, followed by a series of regenerative periodontal surgeries including guided tissue regeneration (GTR) and guided bone regeneration(GBR) to manage advanced bone defects. Six months after periodontal therapy, all implants were inserted using a one-stage approach and Six months later, they were restored with porcelain fused to metal crowns. During the one and two-year follow-ups, the teeth and implants did not show any signs of instability, attachment loss or bone loss. This case report shows that within the limitations of this study a successful outcome can be achieved with an early diagnosis and treatment involving elimination of infectious microorganisms and meticulous long-term maintenance combined with regenerative techniques and implant placement to restore the masticatory function and improve the quality of life for the patient. However further investigation and clinical studies are required to confirm these results. KEYWORDS Stage IV grade C periodontitis; Aggressive periodontitis; Dental implants; Maintenance; Regeneration.

scholarly journals Prevalence and characteristics of aggressive periodontitis

2011 ◽  
Vol 23 (2) ◽  
Author(s):  
Diatri Nariratih ◽  
Janti Rusjanti ◽  
Agus Susanto
Keyword(s):  
Periodontal Disease ◽  
Diagnostic Criteria ◽  
Alveolar Bone ◽  
Bone Destruction ◽  
Aggressive Periodontitis ◽  
Attachment Loss ◽  
Localized Aggressive Periodontitis ◽  
Low Prevalence ◽  
Age Range ◽  
Bilateral Destruction

Aggressive Periodontitis is one of periodontal disease that generally affects individuals less than 30 years old, with a rapid attachment loss and alveolar bone destruction. Special features of the disease are affected incisors and first molars with symmetrical bilateral destruction. The purpose of this study was to determine the prevalence and characteristics of Aggressive Periodontitis at Student Clinics, Faculty of Dentistry Padjadjaran University on May to July 2010. Based on accidentally sampling, 415 new patients at Dental and Oral Hospital, Faculty of Dentistry Padjadjaran University and Dental and Oral Polyclinic at RSUP dr. Hasan Sadikin Bandung participated in this study. Each subject filled out the questionnaire and did a clinical examination. Patients with attachment loss ≥ 4 mm were referred for radiographic and microbiologic examination to support the diagnosis. The results showed that there were 13 patients who have the diagnostic criteria of Aggressive Periodontitis. Nine patients were diagnosed as Localized Aggressive Periodontitis, and 4 patients as Generalized Aggressive Periodontitis. It is concluded that the prevalence of Aggressive Periodontitis was 3.13%, and indicated low prevalence. Characteristics of Localized Aggressive Periodontitis patients were female in 20-29 age range, whereas characteristics of Generalized Aggressive Periodontitis patients were male in 30-39 age range.

scholarly journals Melanotic Neuroectodermal Tumor of Infancy: A Clinicopathological and BRAF V600E Mutation Study of 11 Cases

2021 ◽  
Vol 11 ◽  
Author(s):  
Rong-Hui Xia ◽  
Chun-Ye Zhang ◽  
Li-Zhen Wang ◽  
Yu-Hua Hu ◽  
Jing-Jing Sun ◽  
...  
Keyword(s):  
Bone Destruction ◽  
Tooth Germ ◽  
Oral Pathology ◽  
Clinicopathological Characteristics ◽  
Neuroectodermal Tumor ◽  
Braf V600e ◽  
Amplification Refractory Mutation System ◽  
Epithelioid Cells ◽  
Ki 67

PurposeTo investigate the clinicopathological features and BRAF V600E mutation of melanotic neuroectodermal tumor of infancy (MNTI).Materials and MethodsEleven cases of MNTI diagnosed at the Department of Oral Pathology were collected. Clinicopathological characteristics were obtained from the medical records. Immunostaining was performed by immunohistochemistry (IHC). Amplification-Refractory Mutation System-qPCR (ARMS-qPCR) and Sanger Sequencing were used to detect BRAF V600E mutation.ResultsOf the 11 cases, 3 cases were female and 8 cases were male. The mean age of the first symptoms was 3.2 months (range: 1 to 6 months). Ten cases (90.9%) located in maxilla but only one (9.1%) in mandible. Most of the cases demonstrated well-defined mass with lytic bone destruction and tooth germ affecting radiologically. Histologically, MNTI was consisted of large polygonal melanin-producing epithelioid cells and small round neuroblast-like cells which arranged in irregular alveolar, tubuloglandular and fissured architecture. The epithelioid cells expressed Vim, Pan-CK, NSE and HMB45, while the smalls cells expressed Syn, NSE and scattered Vim. Most cases showed low Ki-67 index (range: <1% to 50%). None of the MNTI cases showed BRAF V600E mutation. Most cases were treated with enucleation (45.4%) or curettage (36.4%). Among the 11 cases, 6 cases had follow-up information, and 2 cases had recurrence lesions after surgery.ConclusionMNTI, an extremely rare tumor, mainly affects male infants with strong preference for maxilla. Distinct histopathological features and immunohistochemical profile are helpful to distinguish from other melanin-containing tumors and small round cell tumors. No BRAF V600E mutation in MNTI is detected in the present study and needs further investigations. The factors that contribute to the local recurrence of MNTI are controversial, but the close follow-up for the patients is recommended.

Genetics and Aggressive Periodontal Disease: An Update Review

2012 ◽  
Vol 6 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Deepika Bali ◽  
Nymphea Pandit ◽  
Rouble Kathuria ◽  
Amit Bali
Keyword(s):  
Periodontal Disease ◽  
Familial Aggregation ◽  
Periodontal Diseases ◽  
Aggressive Periodontitis ◽  
Primary Role ◽  
Nucleotide Polymorphisms ◽  
Related Factors ◽  
Etiologic Agents ◽  
Susceptibility Factors ◽  
Progression Of Disease

ABSTRACT Periodontitis is an inflammatory condition of supporting tissues of teeth, for which several risk and susceptibility factors are proposed. Periodontal disease results when balance between host factors and etiologic agents is disrupted. Bacteria have a primary role in the initiation of periodontal disease, and a range of host related factors influence the clinical presentation and rate of progression of disease. Genetic variations that modify immunological reactions identify the disease susceptibility in various individuals. Many studies have proved the effect of various single or composite nucleotide polymorphisms to susceptibility, progression or severity of periodontal diseases. Despite these studies, association between periodontal disease and candidate genes is still not clear. The reports of familial nature of chronic periodontitis are less frequent as compared to aggressive periodontitis. The striking familial aggregation of trait in aggressive periodontitis is consistent with significant genetic etiology. In this paper, an attempt has been made to summarize recent views on various genes involved in the pathogenesis and progression of aggressive periodontal disease. Data were identified by searches of the Medline, and Pubmed. Articles published in English were selected, and most up-to-date or relevant references were chosen.

A 5-Year Follow-up of an Implant Placed in a Patient with Generalized Aggressive Periodontitis

2011 ◽  
Vol 2 (2) ◽  
pp. 155-158
Author(s):  
J Praveen ◽  
CD Dwarakanath ◽  
Sidharth Shankar ◽  
Lakshmi Bai
Keyword(s):  
Patient Compliance ◽  
Treatment Option ◽  
Pathogenic Bacteria ◽  
Bone Destruction ◽  
Aggressive Periodontitis ◽  
Highly Pathogenic ◽  
Good Patient ◽  
Good Patient Compliance ◽  
Viable Treatment

ABSTRACT The placement of implants in patients with aggressive periodontitis has always been questioned. The presence of highly pathogenic bacteria, severe periodontal bone destruction and the refractory nature of this disease tends to deter the clinician from placing implants in these patients. With good patient compliance and regular maintenance, the placement of implants in these patients becomes a viable treatment option. The following is a report of an implant placed in one such patient and successfully followed up over a period of 5 years.

scholarly journals Prosthetic rehabilatiton of aggressive periodontitis patients: a case series

2019 ◽  
pp. 24-29
Author(s):  
Shraddha Sahni ◽  
Akhil G Rathi ◽  
Usha M Radke
Keyword(s):  
Key Words ◽  
Pathogenic Bacteria ◽  
Clinical Manifestations ◽  
Case Series ◽  
Bone Destruction ◽  
Aggressive Periodontitis ◽  
Early Age ◽  
Highly Pathogenic ◽  
Partial Denture

Aggressive periodontitis (AgP) comprises a group of rare, often severe, rapidly progressive forms of periodontitis which is characterized by an early age of clinical manifestations. It usually affects people under 30 years of age. Microbiota associated are Aggregatibacter, Actinomycetemcomitans and Porphyromonasgingivalis. The presence of highly pathogenic bacteria, severe periodontal bone destruction and the refractory nature of this disease tends to deter the clinician from placing implants in these patients. This article represents case series of patients with generalized aggressive periodontitits (GAP) rehabilitated prosthetically with successful 2 years follow-up. Key Words : Aggressive periodontitis, preservation, cast partial denture

Follow-up of Osteomyelitis of Infants with Systemic Serum Parameters and Bone Scintigraphy

1996 ◽  
Vol 35 (04) ◽  
pp. 116-121 ◽  
Author(s):  
G. E Fueger ◽  
M. Vejda ◽  
R. M. Aigner
Keyword(s):  
Bone Scintigraphy ◽  
Antibiotic Treatment ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Laboratory Findings ◽  
Radiographic Findings ◽  
Serum Parameters ◽  
Wbc Count ◽  
Differential White Blood Cell

Summary Aim: To prevent orthopedic sequelae in acute hematogenous pyogenic osteomyelitis (AHPO) of infants early diagnosis, recognition of recurrence and effective therapy is needed. This retrospective study of 47 infants with bacteriologically confirmed AHPO concerned with an analysis of the diagnostic value of systemic serum parameters compared to bone scintigraphy (BSC). Methods: AHPO was characterized initially and during the course of disease by clinical findings, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), total and differential white blood cell (WBC) count, BSC, and plain radiography. Results: CRP was the most effective serum parameter for follow- up of disease. The first sign of BSC to signal adequate response to antibiotic treatment was the decrease or normalization of hyperperfusion. Escape from therapy or poor prognosis, even when the serum parameters were normalized, was signaled by the recurrence of focal hyperperfusion and the persistent or increasing local uptake ratios on the 3-h-image over 6 weeks during a course of antibiotic treatment. Conclusion: Antibiotic treatment masks the clinical presentation, and the radiographic findings, causes non-characteristic laboratory findings, but do not prevent the scintigraphic visualization; BSC and serum parameters used in the right completion are the most successful and efficient modalities for follow-up of AHPO. Maintenance of antibiotic therapy should be done until BSC findings have reverted to normal.

scholarly journals Periodontal Manifestations in a Patient with Haim-Munk Syndrome

2010 ◽  
Vol 04 (03) ◽  
pp. 338-340
Author(s):  
Kamile Erciyas ◽  
Serhat Inaloz ◽  
A. Fuat Erciyas
Keyword(s):  
Autosomal Recessive ◽  
Alveolar Bone ◽  
Bone Destruction ◽  
Autosomal Recessive Disorder ◽  
Aggressive Periodontitis ◽  
Pes Planus ◽  
Rare Autosomal Recessive Disorder ◽  
Rare Anomaly ◽  
Palmoplantar Hyperkeratosis

Haim-Munk syndrome is an extremely rare autosomal recessive disorder characterized clinically by palmoplantar hyperkeratosis, aggressive periodontitis with severe alveolar bone destruction, onychogryphosis, pes planus, arachnodactyly, and acro-osteolysis. Consanguinity seems a notable prerequisite. The aim of this study was therefore to report one case of this syndrome and to focus on the periodontal manifestations, in order to attract the attention of dental clinicians to this rare anomaly. (Eur J Dent 2010;4:338-340)

scholarly journals Risk Factors for Failure in Conservatively Treated Osteoporotic Vertebral Fractures: A Systematic Review

2021 ◽  
pp. 219256822098227
Author(s):  
Max J. Scheyerer ◽  
Ulrich J. A. Spiegl ◽  
Sebastian Grueninger ◽  
Frank Hartmann ◽  
Sebastian Katscher ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Treatment Failure ◽  
Patient Specific ◽  
Mineral Density ◽  
Radiographic Findings ◽  
Specific Risk ◽  
Fracture Development ◽  
Predict Treatment Failure

Study Design: Systematic review. Objectives: Osteoporosis is one of the most common diseases of the elderly, whereby vertebral body fractures are in many cases the first manifestation. Even today, the consequences for patients are underestimated. Therefore, early identification of therapy failures is essential. In this context, the aim of the present systematic review was to evaluate the current literature with respect to clinical and radiographic findings that might predict treatment failure. Methods: We conducted a comprehensive, systematic review of the literature according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) checklist and algorithm. Results: After the literature search, 724 potentially eligible investigations were identified. In total, 24 studies with 3044 participants and a mean follow-up of 11 months (range 6-27.5 months) were included. Patient-specific risk factors were age >73 years, bone mineral density with a t-score <−2.95, BMI >23 and a modified frailty index >2.5. The following radiological and fracture-specific risk factors could be identified: involvement of the posterior wall, initial height loss, midportion type fracture, development of an intravertebral cleft, fracture at the thoracolumbar junction, fracture involvement of both endplates, different morphological types of fractures, and specific MRI findings. Further, a correlation between sagittal spinal imbalance and treatment failure could be demonstrated. Conclusion: In conclusion, this systematic review identified various factors that predict treatment failure in conservatively treated osteoporotic fractures. In these cases, additional treatment options and surgical treatment strategies should be considered in addition to follow-up examinations.

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