Zapalenie przyzębia u kobiet ciężarnych z cukrzycą i jego kliniczne implikacje – problem wielodyscyplinarny. Przegląd piśmiennictwa

2020 ◽  
Vol 25 (1) ◽  
Author(s):  
Joanna Waligóra ◽  
Maria Chomyszyn-Gajewska ◽  
Jolanta Pytko-Polończyk
Keyword(s):  
Diabetes Mellitus ◽  
Pregnant Women ◽  
Periodontal Diseases ◽  
Health Condition ◽  
Systemic Diseases ◽  
Rapid Diagnostics ◽  
Medical Databases ◽  
Constant Control ◽  
Appropriate Treatment ◽  
Patients With Diabetes

Periodontitis is a multifactorial bacterial infection that causes destruction of tissues surrounding the tooth. Its relationship with numerous systemic diseases was confirmed in vast studies. Concerns of maternal and fetus wellness are raised by gestational diabetes mellitus and prepregnancy diabetes causing need for regular periodontal control. The paper is a review of available literature published in medical databases (PubMed, EMBASE, MEDLINE) and in Polish dental journals in the years 1999-2018. Diabetes is one of the risk factors for periodontitis occurrence and its exacerbation. In pregnant women there may be an exacerbation of the already existing periodontal disease. Periodontitis in pregnant patients with diabetes is associated with the risk of many complications for both the mother and the fetus. Pregnant women with diabetes should be under constant control of a gynecologist, diabetologist and dentist. Periodontal care in such patients should focus on rapid diagnostics of periodontal diseases and the implementation of appropriate treatment. Future mothers should be educated that oral health can affect pregnancy, childbirth and the health condition of mother and the child.

scholarly journals Clinical and cytological characteristic of a condition of the oral cavity at pregnant women with various types of a diabetes mellitus

2016 ◽  
Vol 65 (6) ◽  
pp. 45-51 ◽  
Author(s):  
Ludmila Yu Orekhova ◽  
Anna A Aleksandrova ◽  
Ludmila A Aleksandrova ◽  
Ramila S Musaeva ◽  
Gulrukhsor Kh Tolibova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Oral Cavity ◽  
Pregnant Women ◽  
Inflammatory Diseases ◽  
Type I Diabetes ◽  
Periodontal Diseases ◽  
Diabetes Mellitus Type 1 ◽  
Control Group ◽  
Type I ◽  
Liquid Based Cytology

Introduction. More and more researches dedicated to the communication of diseases of the oral cavity of pregnant women with diabetes. It is proved that the intensity of caries and inflammatory periodontal diseases (gingivitis and periodontitis) increase significantly during pregnancy, while the presence of comorbidities, such as diabetes, increase these indexes.Aim. The aim of the work was to study the dental status of pregnant women with diabetes.Materials and methods. The study compared women with gestational diabetes mellitus, type 1 diabetes, and type 2 diabetes, to a control group of pregnant women without diabetes. In addition to clinical research methods, liquid-based cytology of the contents of the gingival sulcus was performed.Results. The results of clinical and laboratory studies have shown that inflammatory diseases of periodontium and teeth within pregnant women with diabetes are more common than within the pregnant women without this disease. It should be noted that the frequency of occurrence and severity of these diseases in the pregnant women with type I diabetes is higher than in the other groups.Conclusion. Pregnant women with diabetes are at risk for dental disease and require more attention from dentists, endocrinologists and obstetricians. The use of liquid-based cytology method helps in the diagnosis of inflammatory periodontal diseases.

scholarly journals Prevalensi periodontitis pada pasien diabetes mellitus (Studi observasional di poliklinik penyakit dalam RSUP Dr. Sardjito)

2017 ◽  
Vol 3 (2) ◽  
pp. 98 ◽  
Author(s):  
Rezmelia Sari ◽  
Dahlia Herawati ◽  
Rizky Nurcahyanti ◽  
Pramudita Kusuma Wardani
Keyword(s):  
Internal Medicine ◽  
Diabetes Mellitus ◽  
Informed Consent ◽  
Observational Study ◽  
General Hospital ◽  
Oral Hygiene ◽  
Periodontal Diseases ◽  
Central Java ◽  
Patients With Diabetes ◽  
Tissue Attachment

Prevalence of periodontal diseases in patients with  diabetes mellitus (An observational study     at internal medicine polyclinic in  Dr.  Sardjito General Hospital). Diabetes Mellitus (DM) is a  chronic disease    with an increasing prevalence and causes complications. The most frequent complication found in the oral cavity of patients with diabetes mellitus is periodontal diseases is characterized by the loss of tissue attachment. There have been numerous studies on the association of DM with periodontal diseases but there has not been any data on the prevalence of periodontal diseases in diabetic group, especially in Yogyakarta and Central Java. Dr. Sardjito General Hospital is a referral hospital in DIY and Central Java, so this study is expected to provide a picture regarding the level of periodontal tissue health among people in Yogyakarta and Central Java. This research was an observational study, involving 36 patients with DM according to criteria of the subjects: suffering from type 2 diabetes, being cooperative  and willing to sign an informed consent. The controlled variables: being 40 – 60 years of age, having good oral hygiene (OHI) according to Green and Vermillion, taking neither antibiotics nor anti-inammatory drugs in the last 3 months, not having a history of other systemic diseases. Oral hygiene exams were carried out, followed by examination using probe WHO to determine if there is CAL. The data were presented descriptively. The results showed that the prevalence of periodontal diseases in patients with DM at Internal Medicine Polyclinic in Dr. Sardjito General Hospital is 88.24% with a mean of CAL distance of 4.6 mm. The conclusion of this study is that the prevalence of periodontal diseases in patients with DM is high although the oral hygiene status is good. ABSTRAKDiabetes Mellitus (DM) adalah penyakit kronis menahun dengan prevalensi yang semakin meningkat dan menimbulkan komplikasi. Komplikasi yang paling sering terjadi di rongga mulut pasien DM adalah periodontitis yang ditandai dengan kehilangan perlekatan jaringan. Penelitian tentang hubungan DM dengan periodontitis banyak dilakukan namun belum ditemukan data mengenai prevalensi periodontitis pada kelompok  DM  khususnya di DIY dan  Jawa Tengah.  RSUP Dr. Sardjito merupakan rumah sakit rujukan DIY dan Jawa Tengah sehingga penelitian ini diharapkan dapat memberi gambaran mengenai tingkat kesehatan jaringan periodontal di masyarakat DIY dan Jawa Tengah. Jenis penelitian ini adalah observasional dengan melibatkan 36 orang pasien DM sesuai kriteria subjek yaitu menderita DM tipe II, kooperatif dan bersedia menandatangani informed consent. Variabel terkendali yaitu usia 40 – 60 tahun, kebersihan mulut (OHI) menurut Green and Vermillion dalam kriteria baik, tidak menggunakan antibiotik dan antiinamasi dalam 3 bulan terakhir dan tidak memiliki riwayat penyakit sistemik lain. Dilakukan pemeriksaan kebersihan mulut dilanjutkan dengan pemeriksaan menggunakan probe WHO untuk menentukan ada tidaknya CAL. Data disajikan secara deskriptif. Hasil penelitian menunjukkan bahwa prevalensi periodontitis pada pasien DM di Poli Klinik Penyakit Dalam RSUP Dr. Sardjito adalah 88,24% dengan rata-rata jarak CAL adalah 4,6 mm. Kesimpulan penelitian ini adalah prevalensi periodontitis pada pasien DM tinggi walaupun status kebersihan mulut tergolong dalam kriteria baik.

scholarly journals RESOURCES TO IMPROVE THE EFFECTIVENESS OF PERIODONTAL TREATMENT IN PATIENTS WITH DIABETES MELLITUS

2021 ◽  
Vol 74 (3) ◽  
pp. 702-707
Author(s):  
Galyna F. Biloklytska ◽  
Svitlana Yu. Viala
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Periodontal Disease ◽  
Healthy Lifestyle ◽  
Periodontal Diseases ◽  
Well Being ◽  
Type Ii Diabetes Mellitus ◽  
Type I ◽  
Patients With Diabetes ◽  
Local Risk

The aim: Is to characterize the «Medico-sociological map» developed by us to identify systemic and local risk factors for periodontal disease in patients with type I and II diabetes mellitus as a resource to improve the treatment of generalized periodontitis. Materials and methods: We have developed a Medic-sociological map to identify systemic and local risk factors for periodontal disease in patients with type I and type II diabetes mellitus. Methods of accumulation of primary dental and endocrinological information, review and analytical methods. Statistical methods for comparing empirical data and their generalization. Results: Thanks to the «Medico-sociological map» developed by us, systemic and local risk factors for the development of periodontal tissue diseases in patients with type I and II diabetes mellitus have been identified. Factors for improving the well-being of patients in the treatment of periodontal diseases have been comprehensively studied. Patients with type 1 and type 2 diabetes mellitus have been shown to give up healthy habits (cigarette smoking) and lead a healthy lifestyle and reduce the health risks that can be caused by generalized periodontitis in combination with diabetes mellitus. Conclusions: It has been demonstrated that resources to improve the effectiveness of periodontitis treatment in patients with diabetes mellitus include not only cooperation with endocrinologists, but also our «Medico-sociological map» to identify systemic and local risk factors for periodontal disease in patients with type I and II diabetes mellitus.

scholarly journals Diabetes mellitus and periodontal diseases: A two way relationship

2021 ◽  
Vol 6 (2) ◽  
pp. 43-56
Author(s):  
Gowhar Nazir ◽  
◽  
Josee Amin ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Systemic Effect ◽  
Diabetic Patients ◽  
Periodontal Infection ◽  
Bidirectional Relationship ◽  
Patients With Diabetes ◽  
Global Health Care

Diabetes mellitus and periodontits are both highly prevalent chronic inflammatory diseases. Both diseases share the same risk factors and are a significant global health care burden adversely affecting the quality of life. Evidence from various studies have demonstrated that diabetes is a major risk factor for periodontal disease and is associated with increased incidence, prevalence and severity of periodontal disease. Hyperglycemia associated with diabetes mellitus results in an increased host immunoinflammatory response which adversely affects the periodontal health. Conversely, periodontits is associated with poor metabolic control in patients with diabetes and increased development of diabetic complications suggesting a bidirectional relationship between the two diseases. Periodontal infection via bacteremia exerts a wide systemic effect by contributing to chronic systemic inflammatory burden worsening diabetic state by increasing insulin resistance. Moreover, studies have demonstrated an improvement in glycemic control following periodontal therapy in prediabetic and diabetic patients with periodontitis.

Analysis of anti-inflammatory toothpastes efficiency among patients with diabetes mellitus and chronic generalized periodontitis

2020 ◽  
Vol 25 (1) ◽  
pp. 47-53
Author(s):  
L. Yu. Orekhova ◽  
R. S. Musaeva ◽  
E. S. Loboda ◽  
E. V. Grinenko ◽  
A. V. Chuprinina ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Oral Cavity ◽  
Oral Hygiene ◽  
Periodontal Diseases ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Periodontal Tissues ◽  
Patients With Diabetes ◽  
Anti Inflammatory

Relevance. Inflammatory periodontal diseases (IPD) on the background of microangiopathy among patients with diabetes mellitus (DM) are considered one of the main complications. Reduced resistance of periodontal tissues and trophic disorders due to changes in capillary walls leads to development of inflammatory processes with the destruction of gingival joint. The presence of diabetes mellitus in patients with chronic generalized periodontitis requires not only conservative periodontal therapy by a dentist, but also constant maintenance therapy, which consists in the ability of patient to maintain satisfactory oral hygiene and the use of therapeutic and prophylactic toothpastes.Purpose. To evaluate the effectiveness of using toothpastes with anti-inflammatory components among pa-tients with chronic generalized periodontitis and type 1 diabetes after professional oral hygiene complex.Materials and methods. The examination of 60 patients with diabetes mellitus type 1 and chronic generalized periodontitis at the age of 20 to 50 years was conducted. All patients underwent a questionnaire on the presence of complaints about state of the oral cavity and a comprehensive dental examination with definition of basic dental indices. Then, a complex of professional oral hygiene with individual hygiene training was carried out. Patients were divided into groups depending on the prescribed paste with anti-inflammatory components. Repeated examination was carried out after 1 month.Results. In 1 month after conservative therapy was carried out, improvement of all indexes in all groups, improvement of the acid-base state of the oral fluid was found. Patients themselves noted a better way change in state of oral cavity tissues. The best dynamics after treatment complex was observed in the 1st group.Conclusion. Hygienic and periodontal condition of the oral cavity among patients with diabetes mellitus type 1 was initially at a rather low level. It has been revealed that complex of professional oral hygiene and prescription of therapeutic and prophylactic toothpaste improve periodontal status of patients with diabetes.

scholarly journals Comparative characteristics of the fetoplacental complex in women with type 1 diabetes and in pregnant women with gestational diabetes

2019 ◽  
Vol 23 (4) ◽  
pp. 652-658
Author(s):  
A.P. Dnistryanska ◽  
O.S. Musienko ◽  
L.V. Yaremchuk
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Gestational Diabetes ◽  
Pregnant Women ◽  
Termination Of Pregnancy ◽  
Fetoplacental Complex ◽  
Biophysical Profile ◽  
Patients With Diabetes ◽  
History Of

Annotation. In the structure of causes of maternal mortality, extragenital pathology accounts for 25%. Among them, endocrine pathology is 6%, diabetes accounts for 31.9%. 1% of women of childbearing age suffer from type 1 diabetes, and 2–17% has gestational diabetes (GD). The aim is to compare the condition of the fetoplacental complex in the third trimester of pregnancy in 9 pregnant women with type 1 diabetes (group 1) and in 12 women with GD (group 2) who were observed at “Vinnitsa City Clinical Hospital and child” for 2016–2019. The control group included 10 patients with physiological pregnancy. Women with diabetes had a history of gynecological diseases: colpitis (8 patients (88.8%)), cervical erosion (2 (22.2%)), chronic adnexitis (5 (55.5%)). Among the complications of previous pregnancies in the group of patients with diabetes mellitus (5 births) were unauthorized miscarriages (1 (11.1%)), the risk of termination of pregnancy (5 (55%)). In women with a history of GD, colpitis was observed in 3 (24.9%), which is significantly less than in women with type 1 diabetes. There were 2 pregnant women with GD: preterm births (16.6%). Among the complications of pregnancy in 1 patient was the threat of abortion in previous cases. Changes in the indexes of hemodynamics of the uterine-placental complex were evaluated on the basis of cardiotocography, ultrasound on ultrasound machine “Logic-5” with 2D measurement, Doppler, evaluation of the biophysical profile of the fetus (BPF). Statistical data processing was performed by calculating Student coefficients (+) using the Microsoft Excel program. It was established that in the 1st trimester of pregnancy, 5 (55.5%) women with type 1 diabetes were diagnosed with a threat of termination of pregnancy (TTP), and in the 1st (11.1%), they had a retroplacental hematoma. Two (22.2%) women with GD were diagnosed with TTF. In the 2nd trimester, 2 women with GD remained symptomatic of TTF. Six (66.7%) women with type 1 diabetes have symptoms of TTF. In the 1 pregnant woman developed pyelonephritis. Childbirth in 8 (88.8%) women with type 1 diabetes ended through natural birth canal, in 1 woman — a caesarean section. The weight of the child was 4435±2 g. In women with GD the weight of the child was 3756±12. In 7 (77.8%) patients, fetal weight exceeded 4000 g. BPF in the group of patients with diabetes was significantly different from the group with GD at 37–38 weeks of pregnancy. BPF in the 1st group — 7.6±0.2, in the 2nd group — 8.7±0.2, resistance index (RI): 1st group — 0.61±0.01, 2-ha group — 0.57±0.01, CO/K: in the 1st group — 3.2±0.1, in the 2nd group — 3.1±0.1. The correlation between the level of GD compensation and pathological changes in the fetoplacental complex has been established. The data obtained indicate that early screening of this pathology and appropriate compensation for carbohydrate metabolism in the presence of diabetes mellitus should be noted as one of the methods for the prevention of the development of complications in GD.

scholarly journals The role of pro-inflammatory cytokines in diabetic nephropathy in pregnant women with type 1 diabetes mellitus

2013 ◽  
Vol 94 (1) ◽  
pp. 105-110
Author(s):  
G R Gazizova
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Growth Factors ◽  
Pregnant Women ◽  
Inflammatory Cytokines ◽  
Interstitial Fibrosis ◽  
Inflammatory Reactions ◽  
Patients With Diabetes ◽  
Pro Inflammatory Cytokines

Diabetic nephropathy is one of the most frequent and unfavorable complications of pregnancy in terms of prognosis in patients with diabetes mellitus. The combination of pregnancy and uncompensated diabetes with such complications as diabetic nephropathy, diabetic retinopathy, diabetic neuropathy, leads to overproduction of pro-inflammatory cytokines, thromboses and ischemic necroses of the fetoplacental tissues, and low blood level of immunosuppressive cytokines increases the severity of the disease. This mechanism may be one of the reasons of the spontaneous abortion and pregnancy loss in early pregnancy term in women with diabetes. For a long time the leading role in diabetic nephropathy formation was acknowledged for hyperglycemia, dyslipidemia, oxidative stress, and arterial and renal intraglomerular hypertension. Diabetic nephropathy was recognized as non-immune and non-inflammatory process. Currently diabetic nephropathy is considered as a series of inflammatory reactions involving inflammatory cytokines and chemokines, consisting in the migration of monocytes or macrophages to the kidneys and glomerular and interstitial fibrosis development. Recent studies prove the role of immune-inflammatory reactions in diabetic kidney damage development and confirm an imbalance of the collagen exchange regulating factors, even at the stage of reversible renal dysfunction - microalbuminuria. The close relationship found between hyperglycemia, overproduction of growth factors and nephrosclerosis development in diabetes mellitus. The detection of pro-inflammatory cytokines and fibrogenic growth factors in the urine of patients with diabetes, especially in pregnant women with diabetes, can be used to prompt diagnosis and evaluation of processes occurring in the kidneys, to study the degree of sclerosis, and as a consequence, to predict kidney functional disorders development. Keywords: diabetes mellitus, pregnancy, diabetic nephropathy, cytokines, growth factors.

scholarly journals Infusion therapy of sepsis in trauma in patients with diabetes mellitus

2019 ◽  
Vol 41 part 2 (2) ◽  
pp. 9-11
Author(s):  
O. V. Tribushnoj ◽  
Y. P. Klyatsky ◽  
I. I. Trufanov ◽  
O. V. Banit
Keyword(s):  
Diabetes Mellitus ◽  
Inflammatory Process ◽  
Multiple Organ ◽  
Infusion Therapy ◽  
Diabetic Patients ◽  
Foot Injuries ◽  
Foot Bones ◽  
Results Of Treatment ◽  
Constant Control ◽  
Patients With Diabetes

Purpose of the study. Develop schemes for infusion therapy of sepsis with purulent complications of fractures of the foot bones in patients with diabetes mellitus. In order to restore disorders of homeostasis, patients received a complex of medical measures including surgical treatment, infusion therapy, immunotherapy, antibiotic therapy. The results of treatment of 22 diabetic patients with foot injuries that were complicated by purulent-inflammatory process and sepsis were studied. The patients were under the constant control of the endocrinologist. The use of the developed medical tactics allowed improving the results of treatment of patients with diabetes with traumatic sepsis. Keywords: sepsis, multiple organ failure, surgery, infusion therapy.

scholarly journals FEATURES OF MICROBIOLOGICAL AND IMMUNE STATE IN PREGNANT WOMEN WITH INFLAMMATORY PERIODONTAL DISEASES AGAINST THE BACKGROUND OF GESTATIONAL DIABETES MELLITUS

2020 ◽  
Vol 75 (3) ◽  
pp. 83-86
Author(s):  
Ye.I. Alexandrov ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Oral Cavity ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Periodontal Diseases ◽  
Main Group ◽  
Control Group ◽  
Periodontal Health ◽  
Periodontal Tissues

90 pregnant women with inflammatory periodontal diseases, aged 27 to 35 years were examined. The main group consisted of 60 pregnant women with gestational diabetes mellitus and the control one consisted of 30 patients with physiological pregnancy. All patients were examined before providing treatment and preventive measures at 14–15 weeks of pregnancy and after them at 37–38 weeks. Studies have shown deterioration in periodontal health, oral hygiene and increase in contamination of the oral cavity in patients of the main group as compared with patients of the control group. The use of the anti-inflammatory succinic acid based preparation is effective for inflammatory periodontal diseases in pregnant women with gestational diabetes. The improvement of periodontal tissues health was confirmed by the posttreatment indices of hygiene, immunoglobulins, microbiocenosis and periodontal indices that promote normalization of the oral cavity.

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