scholarly journals Three New Polyketides from the Insect-Associated Fungus Letendraea sp. 5XNZ4-2

2021 ◽  
Vol 15 (3) ◽  
pp. 187-193
Author(s):  
Yan Xu ◽  
Nanyan Fu ◽  
Wanjing Ding ◽  
Pinmei Wang ◽  
Jinzhong Xu
Keyword(s):  
Antibacterial Activity ◽  
Single Crystal ◽  
Spectroscopic Data ◽  
Antibacterial Activities ◽  
X Ray Diffraction ◽  
Potato Dextrose Broth ◽  
Etoac Extract ◽  
X Ray ◽  
New Compounds ◽  
Modified Mosher’S Method

Chemical investigation of the EtOAc extract of an insect-associated fungus Letendraea sp. 5XNZ4-2 cultured in Potato Dextrose Broth (1/2 PDB) medium lead to the isolation of three new polyketides, named letendronol D (1), phomopsiketones H-I (2-3). The structures of new compounds were elucidated by the analysis of HRESIMS and NMR spectroscopic data, and the absolute configurations were determined by modified Mosher’s method, ECD calculation and single-crystal X-ray diffraction. Cytotoxicity and antibacterial activities of 1 were assayed and regrettably 1 didn’t display any cytotoxicity and antibacterial activity. 3 was the first phomopsiketone derivative obtaining the lactone.

scholarly journals Zopfiellasins A–D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment

Molecules ◽  
2021 ◽  
Vol 26 (18) ◽  
pp. 5611
Author(s):  
Jie-Yu Zhang ◽  
Juan He ◽  
Zheng-Hui Li ◽  
Tao Feng ◽  
Ji-Kai Liu
Keyword(s):  
Antibacterial Activity ◽  
Data Analysis ◽  
Single Crystal ◽  
Pseudomonas Syringae ◽  
Spectroscopic Data ◽  
Antibacterial Agents ◽  
X Ray Diffraction ◽  
X Ray ◽  
First Report ◽  
The Absolute

In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A–D (1–4), were characterized from the fungus Zopfiella sp. The structures were established on the basis of spectroscopic data analysis, while the absolute configurations were determined by single-crystal X-ray diffraction. Compounds 1 and 3 exhibited antibacterial activity against Psa with MIC values of 25 and 50 μg/mL, respectively. This is the first report of anti-Psa activity of cytochalasin derivatives.

Coordination of N-Heterocyclic Carbene to H2SiX2 (X = Cl, OTf) and H3SiOTf (OTf = OSO2CF3): Synthesis of Donor-stabilized Parent Silylium Salts with Four- and Five-coordinate Silicon Atoms

2013 ◽  
Vol 68 (5-6) ◽  
pp. 445-452 ◽  
Author(s):  
Yun Xiong ◽  
Shenglai Yao ◽  
Matthias Driess
Keyword(s):  
Single Crystal ◽  
Spectroscopic Data ◽  
Ion Pairs ◽  
X Ray Diffraction ◽  
X Ray ◽  
Multinuclear Nmr ◽  
Neutral Compounds ◽  
New Compounds ◽  
Ir Spectroscopic

The reactivity of the N-heterocyclic carbene (NHC) 1,3-bis(2,6-diisopropylphenyl)imidazol-2- ylidene towards dichlorosilane H2SiCl2, bis(trifluoromethanesulfonato)silane H2Si(OTf)2 (OTf = OSO2CF3), and silyl trifluoromethanesulfonate H3SiOTf has been investigated. It turned out that the coordination of the NHC ligand can occur stepwise to form the three neutral compounds (NHC)SiH2Cl2 (1), (NHC)2SiH2Cl2 (2), (NHC)SiH2(OTf)2 (3), as well as the two ion pairs [(NHC)SiH3]+(OTf-) (4) and [(NHC)2SiH3]+(OTf-) (5); the latter represent the first NHC adducts of the parent silylium cation (H3Si+). The multinuclear NMR and IR spectroscopic data of the products reflect the characteristics of four-, five-, and six-coordinate silane complexes. All new compounds were structurally characterized by single-crystal X-ray diffraction analyses

New iboga-type alkaloids from Ervatamia hainanensis

RSC Advances ◽  
2016 ◽  
Vol 6 (36) ◽  
pp. 30277-30284 ◽  
Author(s):  
Zhi-Wen Liu ◽  
Xiao-Jun Huang ◽  
Han-Lin Xiao ◽  
Guo Liu ◽  
Jian Zhang ◽  
...  
Keyword(s):  
Single Crystal ◽  
Spectroscopic Data ◽  
X Ray Diffraction ◽  
X Ray

The structures and absolute configurations of seven new iboga-type alkaloids 1–7 were determined by spectroscopic data, Mosher's method, single crystal X-ray diffraction and ECD analyses.

Synthese und Kristallstrukturen einiger Tetramethylstibonium-Hydrogendicarboxylate / Synthesis and Crystal Structures of Some Tetramethylstibonium Hydrogendicarboxylates

1982 ◽  
Vol 37 (11) ◽  
pp. 1393-1401 ◽  
Author(s):  
Beatrix Milewski-Mahrla ◽  
Hubert Schmidbaur
Keyword(s):  
Hydrogen Bonds ◽  
Crystal Structures ◽  
Spectroscopic Data ◽  
Molar Ratio ◽  
Ionic Structure ◽  
X Ray Diffraction ◽  
X Ray ◽  
Carboxylate Oxygen ◽  
Donor Acceptor ◽  
New Compounds

Reactions of pentamethylantimony (CH3)5Sb with carboxylic acids in the molar ratio 1:2 afford one equivalent of methane and essentially quantitative yields of crystalline tetramothylstibonium hydrogendicarboxylates. Six new compounds of this series have been synthesized using benzoic, o-phthalic, salicylic, 4-ethoxy-salicylic, oxalic, and malic acid, and characterized by analytical and spectroscopic data. An ionic structure with strong hydrogen bonds in the anionic components is proposed.The crystal structures of the hydrogen-dibenzoato (1), hydrogen-ortho-plithalato (2) and 4-ethoxy-hydrogen-salicylate (3) were determined by single crystal X-ray diffraction. The compounds can be described as having ionic lattices with some donor-acceptor inter­actions between the stibonium centers and the carboxylate oxygen atoms. The anions are characterized by strong hydrogen bonds O...H...O. Thus, the (CH3)4Sb-tetrahedron in 1 is distorted by two benzoate oxygon atoms (at 304(2) and 340(2) pin). The cation in 2 is largely undistorted and the anion has a hydrogenphthalate hydrogen bond of d(O...H...O) = 232 pm. The cation-anion contact in 3 is as short as d(Sb-O) = 289 pm rendering the Sb atom pentacoordinate.

The Structure and Antibacterial Activity of Taurine and its Magnesium Complex

2011 ◽  
Vol 366 ◽  
pp. 404-407
Author(s):  
Li Hua Wang
Keyword(s):  
Escherichia Coli ◽  
Antibacterial Activity ◽  
Bacillus Subtilis ◽  
Single Crystal ◽  
Dilution Method ◽  
Monoclinic Space Group ◽  
X Ray Diffraction ◽  
X Ray ◽  
Antibacterial Assay ◽  
Serial Dilution Method

The block single-crystals of taurine were obtained, and its structure was determined by single-crystal X-ray diffraction. The single-crystal X-ray analysis of taurine reveals that the crystal belongs monoclinic, space group P2(1)/c with a = 0.52824(10) nm, b = 1.1647(8) nm, c = 0.79236(13) nm, ß = 94.0850(10). The magnesium complex with taurine has been synthesized in ethanol. The antibacterial assay of the Mg (II) complex was measureed using a modified version of the 2-fold serial dilution method. The results show that the complex shows considerable antibacterial activity against escherichia coli, bacillus subtilis and staphylococcus white.

Mannich Reaction Product of Quinolin-8-ol (Oxine) and its Antibacterial Activity

1997 ◽  
Vol 50 (8) ◽  
pp. 861 ◽  
Author(s):  
Shaheen Faizi ◽  
Bina Shaheen Siddiqui ◽  
Rubeena Saleem ◽  
Farzana Akhtar ◽  
Khursheed Ali Khan ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Single Crystal ◽  
Mannich Reaction ◽  
Gram Negative Bacteria ◽  
X Ray Diffraction ◽  
Gram Positive ◽  
Gram Negative ◽  
Antimicrobial Screening ◽  
X Ray

Quinolin-8-ol (1) on reaction with 2,6-dichloroaniline and m-nitrobenzaldehyde afforded 7-(α-hydroxy- m-nitrobenzyl)quinolin-8-ol (2), which is an unusual Mannich reaction product. The structure of (2) was determined by spectroscopic and single-crystal X-ray diffraction studies. Preliminary antimicrobial screening showed that (1) and (2) have activity against a large number of Gram-positive and Gram-negative bacteria.

AlkalineEarthMetal-Hydride-Iodide Compounds: Syntheses andCrystal Structures of Sr2H3I and Ba5H2I3.9(2)O2

2011 ◽  
Vol 66 (1) ◽  
pp. 21-26
Author(s):  
Olaf Reckeweg ◽  
Francis J. DiSalvo
Keyword(s):  
Single Crystal ◽  
Single Crystals ◽  
Structural Model ◽  
Structure Type ◽  
Lattice Parameters ◽  
Molar Ratio ◽  
X Ray Diffraction ◽  
Space Group ◽  
X Ray ◽  
New Compounds

Single crystals of Sr2H3I andBa5H2I3.9(2)O2 were obtained by reacting Sr or Ba, respectively, with dried and sublimed NH4I in a 4 : 1 molar ratio in silica-jacketed Nb ampoules for 13 h at 1200 K. The crystal structures of the new compounds have been determined by means of single-crystal X-ray diffraction. Sr2H3I crystallizes in a stuffed anti-CdI2 structure isotypic to Ba2H3Cl in the space group P3m1 (no. 164) with the lattice parameters a = 426.0(1) and c = 774.9(2) pm, while Ba5H2I3.9(2)O2 crystallizes in a new structure type in the space group Cmcm (no. 63) with the lattice parameters a = 1721.0(2), b = 1452.5(2) and c = 639.03(9) pm. The structural results for Sr2H3I are corroborated by EUTAX calculations. For the disordered compound Ba5H2I3.9(2)O2, EUTAX calculations on an approximated, ordered structural model were used to find possible insights into the disorder

New quinolinone alkaloids from the heartwood of, Euxylophora paraensis

1981 ◽  
Vol 34 (8) ◽  
pp. 1625 ◽  
Author(s):  
L Jurd ◽  
RY Wong
Keyword(s):  
Single Crystal ◽  
Spectroscopic Data ◽  
X Ray Diffraction ◽  
X Ray

The heartwood of Euxylophora paraensis Hub. (Rutaceae) has given N-methylflindersine (2),spectabiline (3), skimmianine (4) and two new alkaloids, identified from spectroscopic data as 4-hydroxy-2,2,6-trimethyl-3,4,5,6-tetrahydro-2H-pyrano[3,2-c]quinolin-5-one (5) and 4-(2,3-dihydroxy-3-methylbutoxy)-1-methylquinolin-2(1H)-one (6). Five new dimeric quinolinone alkaloids, C30H30N2O4, were isolated. The structure of one of these, paraensidimerin D, has now been shown by single-crystal X-ray diffraction methods to be (11), viz. (6aα,7α,14aα)-6,6,9,16- tetramethyl-7-(2-methylprop-1-enyl)-6,6a,7,9,14a,16-hexahydro-8H,15H- quino[3'',4'':5',6'] pyrano [2',3':4,5] pyrano-[3,2-c]quinoline-8,15- dione.

scholarly journals ISOLATION AND STRUCTURAL ELUCIDATION OF A NEW DEPSIDE OF LICHEN Everniopsis trulla

2021 ◽  
Vol 87 (2) ◽  
pp. 97-106
Author(s):  
Olivio Nino Castro ◽  
Jesús López Rodilla ◽  
Sofia Pombal ◽  
Francisca Sanz González ◽  
Julio Santiago Contreras
Keyword(s):  
Mass Spectrometry ◽  
Melting Point ◽  
Hydrogen Bonds ◽  
Single Crystal ◽  
Spectroscopic Data ◽  
Intermolecular Forces ◽  
X Ray Diffraction ◽  
Intermolecular Hydrogen Bonds ◽  
X Ray ◽  
Uv Visible

In this research, a new depside of the lichen Everniopsis trulla has been isolated. The extraction was carried out to 400 g of dry sample and ground with ethanol for 3 repetitions, then, it was fractionated by applying column chromatography with the CHCl3-MeOH system and purified by recrystallization with MeOH-Acetone (1: 1); Finally, white crystals in the form of needles (solid C) with a melting point of 198 ° C were obtained, whose structure was elucidated based on spectroscopic data (UV-Visible, IR, NMR-H1, NMR-C13, mass spectrometry and single crystal X-ray diffraction). According to the Science Finder databases, it is a new depside, called trullarin, and it is observed that molecular packing is influenced by both intramolecular and intermolecular forces. Intermolecular hydrogen bonds of O - H -O type binds neighboring molecules forming dimers.

scholarly journals Secondary Metabolites with α-Glucosidase Inhibitory Activity from the Mangrove Fungus Mycosphaerella sp. SYSU-DZG01

Marine Drugs ◽  
2019 ◽  
Vol 17 (8) ◽  
pp. 483 ◽  
Author(s):  
Pei Qiu ◽  
Zhaoming Liu ◽  
Yan Chen ◽  
Runlin Cai ◽  
Guangying Chen ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Secondary Metabolites ◽  
Single Crystal ◽  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Spectroscopic Data ◽  
X Ray Diffraction ◽  
X Ray ◽  
Ic50 Values ◽  
New Metabolites

Four new metabolites, asperchalasine I (1), dibefurin B (2) and two epicoccine derivatives (3 and 4), together with seven known compounds (5–11) were isolated from a mangrove fungus Mycosphaerella sp. SYSU-DZG01. The structures of compounds 1–4 were established from extensive spectroscopic data and HRESIMS analysis. The absolute configuration of 1 was deduced by comparison of ECD data with that of a known structure. The stereostructures of 2–4 were further confirmed by single-crystal X-ray diffraction. Compounds 1, 8 and 9 exhibited significant α-glucosidase inhibitory activity with IC50 values of 17.1, 26.7 and 15.7 μM, respectively. Compounds 1, 4, 6 and 8 showed antioxidant activity by scavenging DPPH· with EC50 values ranging from 16.3 to 85.8 μM.

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