scholarly journals Analisis Perpindahan Lateral Struktur Beton Bertulang Pada Bangunan Bertingkat Beraturan dan Ketidak Beraturan Horizontal

2020 ◽  
Vol 3 (1) ◽  
pp. 19
Author(s):  
Jawarta Simamora ◽  
Leonardus Setia Budi Wibowo ◽  
Didik Purwanto ◽  
Norman Ray

The effect of earthquake forces on buildings will certainly be different if applied to regular and irregular buildings. The performance of structures produced in irregular buildings will be different from the performance of irregular building structures for the same load intensity. In the earthquake resistant structure planning regulations, SNI 1726-2012 concerning structural irregularities. Where in this regulation there are two types of structural irregularities namely horizontal structural irregularities and vertical structural irregularities which are then subdivided into several types of irregularity. The study was carried out to compare the results of building structure performance with horizontal irregularity compared to regular buildings as seen from displacement, drift ratio, base shear, performance level based on ATC-40, differences in reinforcement weight. This research resulted in the largest displacement for the x-direction, namely the type A irregular building where it experiences a deviation of 0,49 m difference and for the y-direction of 0,44 m in the type A irregular building Type A. The biggest drift ratio of the x-direction and direction y is a Type B irregular building that is equal to 0,64 m for the x-direction and 0.57 m for the y-direction. The largest base shear occurs in regular buildings with Type B irregular buildings at 16.34%. the level of performance based on ATC-40 for all building models is immidiate occupancy, the biggest reinforcement need is the irregular building model B with a percentage difference of 11,20%.

2013 ◽  
Vol 40 (7) ◽  
pp. 655-662
Author(s):  
George K. Georgoussis

Building structures of low or medium height are usually designed with a pseudostatic approach using a base shear much lower than that predicted from an elastic spectrum. Given this shear force, the objective of this paper is to evaluate the effect of the element strength assignment (as determined by several building codes) on the torsional response of inelastic single-storey eccentric structures and to provide guidelines for minimizing this structural behaviour. It is demonstrated that the expected torque about the centre of mass (CM) may be, with equal probability, positive (counterclockwise) or negative (clockwise). This result means that the torsional strength should also be provided in equal terms in both rotational directions, and therefore the base shear and torque (BST) surface of a given system must be symmetrical (or approximately symmetrical). In stiffness-eccentric systems, appropriate BST surfaces may be obtained when a structural design is based on a pair of design eccentricities in a symmetrical order about CM, and this is shown in representative single-storey building models under characteristic ground motions.


Author(s):  
Sudhir Kumar

Abstract: Many past earthquake studies show that during strong vibrations, the adjacent building structures which are closely spaced to each other are vulnerable to severe damage when the adjacent buildings are not at an adequate distance to accommodate their relative displacements. The primary goal of this research is to find out the minimum separation gap between buildings of varying height at the same floor-to-floor height level. SAP 2000 software is used to analyze the structural behavior of building during the earthquake.Three building models are taken for the study, one is six floors (G+6) and another two are nine floors (G+9), and twelve floors (G+12) respectively. Six floors (G+6)& twelve floors (G+12) structures have the same floor to floor height and plan and same beam and column size (equal stiffness) and G+9 buildings have floor to floor height are same but different beam and column sizes (different stiffness). The linear dynamic (RSA) analysis method is used to calculate the response (Displacement, frequency at fundamental time, Base Shear) of the structure at different floors levels. Response (top story displacements) calculated from the response spectrum is compared with the provisions of seismic gap per story height given in IS 4326: 2005.


2019 ◽  
Vol 4 (4) ◽  
pp. 71 ◽  
Author(s):  
Anupoju Rajeev ◽  
Naveen Kumar Meena ◽  
Kumar Pallav

In India, damage cause by some major earthquakes, such as India/Nepal 2015, Sikkim 2011, Kashmir 2005, Bhuj 2001, Latur 1993, and Uttarkashi 1991, have raised alarms to professionals. The probability of seismic risk is higher in more densely populated Indian cities, such as Bhuj, Kashmir, Sikkim, Uttarkashi, as they come under the highest seismicity zone in India. Therefore, our primary interest is to investigate the seismic performance evaluation of the buildings in these seismic prone areas. Significant research has been conducted on the seismic performance of existing buildings. However, investigations on the seismic performance of a building with different country codes for the same earthquake event has not been explored, which is crucial in providing a deeper knowledge of the seismic performance of buildings. This paper presents a comparative study of an Ordinary Moment Resistant Frame (OMRF) building designed using three major codes, Indian (IS: 456-2000, IS: 1893-2002), British (BS: 8110-1997) and European (EC-2, EC-8). Six typical building models considered with earthquake (WiEQ), and without earthquake (WoEQ), and their assessments were interpreted using non-linear static analysis for determining their seismic performance. Seismic performance is compared in terms of base shear coefficient (BSC) and drift ratio that shows WiEQ models, at the drift ratio of 1.5%, the BSC was as follows; 0.78, 0.88, and 0.96 for the models designed for British, Euro, and Indian codes, respectively. The results show that the building models, that have been designed for the Indian codal provisions for both cases, performed well as compared to the other country codes. Base shear and drift ratio are the vital parameters that vary considerably among the building models. This aspect of the Indian code makes it a safer design methodology with higher reserve strength and a reasonably good displacement capacity before reaching the Collapse Prevention (CP) performance level.


Author(s):  
S. Fujinaga ◽  
K. Maruyama ◽  
C.W. Williams ◽  
K. Sekhri ◽  
L. Dmochowski

Yumoto and Dmochowski (Cancer Res.27, 2098 (1967)) reported the presence of mature and immature type C leukemia virus particles in leukemic organs and tissues such as lymph nodes, spleen, thymus, liver, and kidneys of SJL/J strain mice with Hodgki's-like disease or reticulum cell neoplasm (type B). In an attempt to ascertain the possibility that this neoplasia may be of viral origin, experiments with induction and transmission of this neoplasm were carried out using cell-free extracts of leukemic organs from an SJL/J strain mouse with spontaneous disease.It has been possible to induce the disease in low-leukemia BALB/c and C3HZB strain mice and serially transfer the neoplasia by cell-free extracts of leukemic organs of these mice. Histological examination revealed the neoplasia to be of either reticulum cell-type A or type B. Serial transfer is now in its fifth passage. In addition leukemic spleen from another SJL/J strain mouse with spontaneous reticulum cell neoplasm (type A) was set up in tissue culture and is now in its 141st serial passage in vitro. Preliminary results indicate that cell-free material of 39th tissue culture passage can reproduce neoplasia in BALB/c mice.


1992 ◽  
Vol 68 (03) ◽  
pp. 297-300 ◽  
Author(s):  
Monica Galli ◽  
Paul Comfurius ◽  
Tiziano Barbui ◽  
Robert F A Zwaal ◽  
Edouard M Bevers

SummaryPlasmas of 16 patients positive for both IgG anticardiolipin (aCL) antibodies and lupus anticoagulant (LA) antibodies were subjected to adsorption with liposomes containing cardiolipin. In 5 of these plasmas both the anticardiolipin and the anticoagulant activities were co-sedimented with the liposomes in a dose-dependent manner, whereas in the remaining cases only the anticardiolipin activity could be removed by the liposomes, leaving the anticoagulant activity (LA) in the supernatant plasma. aCL antibodies purified from the first 5 plasmas were defined as aCL-type A, while the term aCL-type B was used for antibodies in the other 11 plasmas, from which 2 were selected for this study.Prolongation of the dRVVT was produced by affinity-purified aCL-type A antibodies in plasma of human as well as animal (bovine, rat and goat) origin. aCL-type B antibodies were found to be devoid of anticoagulant activity, while the corresponding supernatants containing LA IgG produced prolongation of the dRVVT only in human plasma.These anticoagulant activities of aCL-type A and of LA IgG's were subsequently evaluated in human plasma depleted of β2-glycoprotein I (β2-GPI), a protein which was previously shown to be essential in the binding of aCL antibodies to anionic phospholipids. Prolongation of the dRVVT by aCL-type A antibodies was abolished using β2-GPI deficient plasma, but could be restored upon addition of β2-GPI. In contrast, LA IgG caused prolongation of the dRVVT irrespective of the presence or absence of β2-GPI.Since β2-GPI binds to negatively-charged phospholipids and impedes the conversion of prothrombin by the factor Xa/Va enzyme complex (Nimpf et al., Biochim Biophys Acta 1986; 884: 142–9), comparison was made of the effect of aCL-type A and aCL-type B antibodies on the rate of thrombin formation in the presence and absence of β2-GPI. This was measured in a system containing highly purified coagulation factors Xa, Va and prothrombin and lipid vesicles composed of 20 mole% phosphatidylserine and 80 mole% phosphatidylcholine. No inhibition on the rate of thrombin formation was observed with both types of aCL antibodies when either β2-GPI or the lipid vesicles were omitted. Addition of β2-GPI to the prothrombinase assay in the presence of lipid vesicles causes a time-dependent inhibition which was not affected by the presence of aCL-type B or non-specific IgG. In contrast, the presence of aCL-type A antibodies dramatically increased the anticoagulant effect of β2-GPI. These data indicate that the anticoagulant activity of aCL-type A antibodies in plasma is mediated by β2-GPI.


2013 ◽  
Vol 1 (1) ◽  
pp. 10
Author(s):  
Noar Muda Satyawan ◽  
Shelly Tutupoho ◽  
Yusli Wardiatno ◽  
Makoto Tsuchiya

Erosion rate on corals due to activities of other biota is called bioerosion. The rock-boring urchin, Echinometra mathaei, when it is abundant, plays a significant role in benthic ecosystems, including biological processes like coral erosion. During feeding, E. mathaei erodes calcium carbonate besides grazing on algae living on coral, so it plays an important role in both organic and inorganic carbons in coral reefs. The urchin E. mathaei actively feeds during the night time (nocturnal grazer). Although in Okinawa four types (A-D) of the urchin exist, the research only focused on the types A and B. Type A of E. mathaei produced 0.44951 g feces per day on average while type B produced 0.38030 g feces per day. CaCO3 analysis in feces and gut contents showed bioerosion rate of E. mathaei type A was 0.64492 g/individu/day, and 0.54436 g/individu/day in type B. There were no significant differences in bioerosion impact of E. mathaei type A and B© Laju erosi pada karang yang disebabkan oleh biota, dikenal dengan bioerosi. Bulu babi jenis Echinometra mathaei, ketika melimpah, menjadi sangat berpengaruh terhadap ekosistem bentik termasuk proses biologi seperti erosi karang. Selama aktivitas makan, E. mathaei menggerus kalsium karbonat dalam proporsi yang besar di samping alga yang tumbuh menempel pada karang sehingga memiliki peran penting dalam siklus karbon organik dan anorganik di ekosistem terumbu karang. Bulu babi E. mathaei aktif mencari makan pada malam hari (nocturnal grazer). Meskipun di Okinanawa ada 4 tipe (A-D), pada eksperimen kali ini memfokuskan pada tipe A dan B saja. Tipe A E. mathaei rata-rata memproduksi 0,44951 g feses/hari dan tipe B memproduksi 0,38030 g feses/hari. Berdasarkan analisis CaCO3 yang dilakukan pada feses dan isi lambung, laju bioerosi yang disebabkan oleh E. mathaei tipe A sebesar 0,64492 g/individu/hari sedangkan tipe B sebesar 0,54436 g/individu/hari. Tidak terdapat perbedaan dampak bioerosi yang signifikan antara E. mathaei tipe A dan B©


2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii41-ii41
Author(s):  
Junjie Zhen ◽  
Lei Wen ◽  
Shaoqun Li ◽  
Mingyao Lai ◽  
Changguo Shan ◽  
...  

Abstract BACKGROUND According to EANO-ESMO clinical practice guidelines, the MRI findings of LM are divided into 4 types, namely linear enhancement (type A), nodular enhancement (type B), linear combined with nodular enhancement (type C), and sign of hydrocephalus (type D). METHODS The MRI features of brain and spinal cord in patients diagnosed with NSCLC-LM in Guangdong Sanjiu Brain Hospital from 2010 until 2019 were investigated, and then were classified into 4 types. The imaging features were analyzed. RESULTS A total of 80 patients were enrolled in the study. The median age of the patients was 53.5 years old, and the median time from the initial diagnosis to the confirmed diagnosis of LM was 11.6 months. The results of enhanced MRI examination of the brain in 79 cases showed that the number of cases with enhancements of type A, B, C and D were 50 (63.3%), 0, 26 (32.9%) and 3 (3.8%), respectively, and that LM with metastases to the brain parenchyma was found in 42 cases (53.2%). The results of enhanced MRI examination of spinal cord in 59 cases showed that there were only enhancements of type A and C in 40 cases (67.8%) and 3 cases (5.0%), and no enhancement sign in the other 16 cases (27.2%). CONCLUSION MRI examination of brain and spinal cord will improve the detection rate of LM. The MRI features of NSCLC-LM in real world are mainly characterized by the linear enhancements of brain and spinal cord, followed by linear combined with nodular enhancement. The enhancements of type B and type D are rare in clinic. Almost half of the patients have LM and metastases to the brain parenchyma. Therefore, the differentiation of tumor metastases is needed to be paid attention to for the early diagnosis and the formulation of reasonable treatment plans.


BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Hüseyin Can ◽  
Sedef Erkunt Alak ◽  
Ahmet Efe Köseoğlu ◽  
Umut Şahar ◽  
Berna Bostanbaş ◽  
...  

Abstract Background Cytidine monophospho-n-acetylneuraminic acid hydroxylase (CMAH) gene associated with blood groups in cats encodes CMAH enzyme that converts Neu5Ac to Neu5Gc. Although variations in CMAH gene of pedigree cats have been revealed, the presence/lack of them in non-pedigree stray cats is unknown. Therefore, the present study aimed to investigate the variations in CMAH gene and the quantity of Neu5Ac and Neu5Gc on erythrocytes of non-pedigree stray cats (n:12) living in İzmir, Turkey. Also, the frequency of blood types was determined in 76 stray cats including 12 cats that were used for CMAH and Neu5A/Neu5Gc analysis. Results In total, 14 SNPs were detected in 5’UTR as well as in exon 2, 4, 9, 10, 11 and 12 of CMAH gene. Among these SNPs, -495 C > T in 5’UTR was detected for the first time as heterozygous in type A and AB cats, and homozygous and heterozygous in type B cats. The remaining 13 that have been detected in previous studies were also found as homozygous or heterozygous. Both Neu5Gc and Neu5Ac were detected in type A and AB cats. In type B cats, only Neu5Ac was detected. Among two type AB cats, the level of Neu5Ac was found higher in cat carrying heterozygous form (T/C) of 1392T > C. The prevalence of type B cats (67.1 %) was higher than others. Conclusions The presence of a new SNP as well as previous SNPs indicates that more variations can be found in stray cats with a more comprehensive study in the future. Also, the high prevalence of type B cats demonstrates the possible risk of neonatal isoerythrolysis among stray cats living in İzmir, Turkey.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T Yamaguchi ◽  
M Nakai ◽  
Y Sumita ◽  
Y Miyamoto ◽  
H Matsuda ◽  
...  

Abstract Background Despite recent advances in diagnosis and management, the mortality of acute aortic dissection (AAD) remains high. Purpose This study aims to develop quality indicators (QIs) for the management of AAD, and to evaluate the associations between QIs and outcomes of AAD in a Japanese nationwide administrative database. Methods A total of 18,348 patients suffered from AAD (Type A: 10,131, Type B: 8,217) in the Japanese Registry of All Cardiac and Vascular Diseases database between 2012 and 2015 were studied. A systematic review was performed to establish initial index items for QIs. Evaluation was performed through the expert consensus meeting using a Delphi method. Associations between developed QIs and the mortality were determined by multivariate mixed logistic regression analyses. Results A total of nine QIs (five structural and four processatic) were developed. Achievements of developed QIs (High: 7–9, Middle: 4–6, Low: 0–3) were significantly associated with lower in-hospital mortality even after adjustment for covariates in both type A (Middle: odds ratio [OR], 0.257; 95% confidence interval [CI], 0.211–0.312; P<0.001; High: OR, 0.064; 95% CI, 0.047–0.086; P<0.001 vs. Low) and type B (Middle: OR, 0.447; 95% CI, 0.338–0.590; P<0.001; High: OR, 0.128; 95% CI, 0.077–0.215; P<0.001 vs. Low). Additionally, achievements of structural and processatic QIs were consistently associated with reduced in-hospital mortality. QIs and in-hospital mortality Conclusions Developed QIs for AAD management were significantly associated with lower in-hospital mortality. Evaluation of each hospital's management with QIs could be helpful to equalize quality of treatment and to fill the evidence-to-practice gaps in the real-world treatment.


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