scholarly journals Cotard Syndrome in recurrent depressive disorder: case report

2021 ◽  
Vol 21 (4) ◽  
pp. 837-842
Author(s):  
Héctor Ocampo Ramos ◽  
Richard Jeremy Febres Ramos ◽  
Sheron Arestegui Saavedra ◽  
Rosa Bravo Torres ◽  
Danitza Cardenas Peralta
Keyword(s):  
Social Life ◽  
Scientific Literature ◽  
Psychiatric Treatment ◽  
The Body ◽  
Medical Progress ◽  
Symptoms Of Depression ◽  
Affective Symptoms ◽  
Suicidal Attempts ◽  
History Of ◽  
To Receive

The Cotard Syndrome, also known as delirium of negation or nihilistic delirium, was described by the French neurologist, Julius Cotard, on June 1880. From that time until the end of the 20th century, in scientific literature, approximately 100 cases were reported that presented symptoms of depression, anxiety, nihilist delusions concerning the body and existence, hypochondriacal and immortality delusions, as well as auditory and visual hallucinations. We present the case of a female patient, 73-years old, from Ayacucho, with a history of sexual assault at the age of 12 and suicidal attempts on 2 occasions, diagnosed with depression at 40 years of age, received treatment with quetiapine, trazadone and clonazepam. She remained with fluctuating medical progress, with symptoms worsening with stressors such as the death of her mother and husband and when she underwent surgeries. Currently, she presents sad and anxious mood, daily crying, ideas of guilt, disability and death, insomnia of conciliation, nihilistic delusive ideas concerning the body, referring that her stomach and bladder do not work, reason why she doesn’t want to eat or drink water. Due to the total refusal of food intake and persistent suicidal ideation, she was hospitalized to receive psychiatric treatment and nutritional support. It is concluded that there are few cases reported on the use of psychotherapy in Cotard's syndrome. Therefore, this case in which psychotherapy was indicated to reduce anxious-affective symptoms, to avoid isolation of the person and to redirect his personal and social life, is important.

Comorbid depression and ulcerative colitis – is there a connection?

2017 ◽  
Vol 41 (S1) ◽  
pp. S534-S534
Author(s):  
A. Melada ◽  
I. Krišto-Mađura ◽  
A. Vidović
Keyword(s):  
Ulcerative Colitis ◽  
Psychiatric Treatment ◽  
Psychiatric Symptoms ◽  
Specific Treatment ◽  
Unknown Etiology ◽  
Suicidal Thoughts ◽  
Symptoms Of Depression ◽  
Bidirectional Communication ◽  
History Of ◽  
Competing Interest

Ulcerative colitis (UC) is a subset disorder of inflammatory bowel disease (IBD) with chronic course and symptoms such as fatigue, gastrointestinal pain, fever, etc. IBD is associated with psychological manifestations including depression and anxiety. There is an increased number of studies trying to link these comorbidities. The gut-brain axis is regulated by intestinal microbiota and this bidirectional communication including immune, neural, endocrine and metabolic mechanisms may bring us closer to the answer. The following case concerns a 56-year-old patient with history of major depressive disorder who was in continuous psychiatric care and treated with antidepressants. Several years after the beginning of psychiatric treatment, he was hospitalized for diagnostic examination due to subfebrility of unknown etiology, but with no final somatic diagnosis. After two years he was referred to our department and at administration the patient showed symptoms of depression, anxiety, lack of motivation and suicidal thoughts and tendencies. Subfebrility was still present at that time. His psychopharmacotherapy was revised and there was a slight improvement in mood and behaviour. During outpatient follow-ups the symptoms of depression were still prominent and remission was not achieved even with modulation of antidepressant pharmacotherapy. The following year the patient was diagnosed with UC and started specific treatment after he presented with diarrhea in addition to subfebrility. Subsequently his mood improved, suicidal thoughts were diminished and ultimately remission was achieved. This case suggests that only after UC was being treated the psychiatric symptoms also withdrew which implicates that inflammatory mediators were involved in pathogenesis of depression.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The Two Bodies of Christ: Communion Frequency and Ecclesiastical Discourse in Pre–Vatican II Australian Catholicism

2010 ◽  
Vol 79 (2) ◽  
pp. 359-409
Author(s):  
Gavin Brown
Keyword(s):  
Vatican Ii ◽  
Fourth Century ◽  
The Body ◽  
Body Of Christ ◽  
Second Vatican Council ◽  
Vatican Council ◽  
History Of ◽  
To Receive ◽  
The Church ◽  
Two Bodies

Today, most Catholics attending Mass come forward to receive communion as a matter of course. But this fact actually belies a very long history of low communion frequency and an institution's often losing struggle to have Catholics regularly receive the body of Christ. Already by the end of the fourth century, communion frequency in the Church, both East and West, had declined rapidly. Thereafter, outside small circles of especially devout communicants, communion at Mass remained for most Catholics an infrequent act. Yet during the mid-twentieth century, in the space of just a few decades, this situation showed signs of quite dramatic reversal. In the nineteenth century in Australia, average communion frequency among most practising Catholics was relatively nominal—perhaps three or four times a year was typical. On the eve of the Second Vatican Council, however, most Catholics in Australia were partaking of communion fortnightly and even weekly. Why this shift? What happened in the course of a generation which turned around a situation spanning many centuries in the Church's tradition of eucharistic worship?

population of potential patients, but be such that they produce different effects when a patient is switched from formulation T to formulation R or vice-versa. In other words there is a significant subject-by-formulation interaction. To show that this is not the case T and R have to be shown to be IBE, i.e., individually bioequivalent. The measure of IBE that has been suggested by the regulators is an aggregate measure involving the means and variances of T and R and the subject-by-formulation inter-action. We will describe this measure in Section 7.4. In simple terms PBE can be considered as a measure that permits patients who have not yet been treated with T or R to be safely prescribed either. IBE, on the other hand, is a measure which permits a patient who is cur-rently being treated with R to be safely switched to T (FDA Guid-ance, 1997, 1999a,b, 2000, 2001). It is worth noting that if T is IBE to R it does not imply that R is IBE to T. The same can be said for PBE. An important practical implication of testing for IBE is that the 2×2 cross-over trial is no longer adequate. As will be seen, the volunteers in the study will have to receive at least one repeat dose of R or T. In other words, three-or four-period designs with sequences such as [RTR,TRT] and [RTRT,TRTR], respectively, must be used. The measures of ABE, PBE and IBE that will be described in Sec-tions 7.2, 7.5 and 7.4 are those suggested by the regulators. Dragalin and Fedorov (1999) and Dragalin et al. (2002) have pointed out some drawbacks of these measures and suggested alternatives which have more attractive properties. We will consider these alternatives in Section 7.7. All the analyzes considered in Sections 7.2 to 7.4 are based on sum-mary measures (AUC and Cmax) obtained from the concentration-time profiles. If testing for bioequivalence is all that is of interest, then these measures are adequate and have been extensively used in practice. How-ever, there is often a need to obtain an understanding of the absorb-tion and elimination processes to which the drug is exposed once it has entered the body, e.g., when bioequivalence is not demonstrated. This can be done by fitting compartmental models to the drug con-centrations obtained from each volunteer. These models not only pro-vide insight into the mechanisms of action of the drugs, but can also be used to calculate the AUC and Cmax values. In Section 7.8 we de-scribe how such models can be fitted using the methods proposed by Lindsey et al. (2000a). The history of bioequivalence testing dates back to the late 1960s and early 1970s. Two excellent review articles written by Patterson (2001a, 2001b) give a more detailed description of the history, as well as a more extensive discussion of the points raised in this section. The regulatory

2003 ◽  
pp. 351-351
Keyword(s):  
Practical Implication ◽  
The Body ◽  
Repeat Dose ◽  
Extensive Discussion ◽  
Time Profiles ◽  
History Of ◽  
The Subject ◽  
Bioequivalence Testing ◽  
To Receive ◽  
Insight Into

scholarly journals A CULTURE OF SELFISHNESS AS A FACTOR IN THE CONTINUATION OF THE PANDEMIC

2021 ◽  
Vol 5 (4) ◽  
pp. 409-416
Author(s):  
A.V. Merenkov
Keyword(s):  
Social Life ◽  
Negative Attitude ◽  
Point Of View ◽  
The Body ◽  
Medical Community ◽  
Public Places ◽  
Compulsory Vaccination ◽  
History Of ◽  
Living Organisms ◽  
True Knowledge

The pandemic, which lasts for two years, has significantly changed all aspects of people's social life due to restrictions on the usual forms of behavior of people in everyday life, public places, and at work. A person is put in a situation of choice: either continue to interact with relatives, friends, colleagues at work on the basis of stereotypes of behavior, but in a pandemic that poses a threat of unintentional infection with coronavirus, or strictly observe the rules of partial or complete isolation. The practice of organizing the behavior prescribed by the sanitary service of large groups of people has shown that a significant part of the population resists the requirements to wear personal protective equipment, to vaccinate with promptly created vaccines against coronavirus. Authorities are forced to impose increasingly stringent measures on violators of doctors' instructions. In the article, the clash of individual and public interests in a pandemic situation is analyzed from the point of view of a theory that reveals the essence and content of a culture of selfishness. It is a system created by people throughout the history of social development to increase the natural selfishness given to all living organisms, including humans. Some social groups, through cunning, lying, psychological and physical coercion, provide personal benefits, while others use these behaviors to preserve themselves, their families. The negative attitude of people to regulations that destroy traditional social ties, compulsory vaccination is considered as a manifestation of individual and group selfishness, formed on the basis of affirming the priority of personal freedom, their own ideas about how to protect the body from various diseases. In the actions of the part of the medical community that is trying not by the method of explanation, persuasion to develop a vaccination kit in people, but to force with the help of severe restrictions to force it, corporate selfishness is being implemented. Those who are guided by it attribute their possession of true knowledge to themselves, rejecting other options for combating the pandemic. The article states that acting on the basis of values and norms of a culture of cooperation, it is possible to achieve the desired success in suppressing coronavirus infection. The conditions for the transition of social subjects from the implementation of the rules of a culture of egoism to the adoption of values and norms of a culture of cooperation are revealed.

scholarly journals FROM THE HISTORY OF FEMINIST RESEARCH OF FEMALE BODY AND SEXUALITY IN ENGLISH-SPEAKING AND EUROPEAN COUNTRIES

2020 ◽  
pp. 18-22
Author(s):  
I. Ihnatenko
Keyword(s):  
Social Life ◽  
Female Body ◽  
Sexual Difference ◽  
The Body ◽  
Embodied Experience ◽  
Feminist Literature ◽  
History Of ◽  
English Speaking ◽  
And Control ◽  
Female Power

This article presents the analysis of the feminism history toward the female body, which has figured alternately as the source of women's oppression and as the locus of a specifically female power. Drawing on Europian and American feminist literature, the author of the article shows how feminist scholars focus first of all on the reproductive body and on female's sexuality. The key message of all these scientific works is that corporealities of women may be seen as making vulnerable to male domination and control, both directly through the exercise of superior physical power, and indirectly through social compulsions and the representation of sexual difference across a variety of discourses. It is shown that for feminist scholars, the body has always been of central importance for understanding women embodied experience, cultural and historical construction on the female body in the various contexts of social life.

scholarly journals La polonité des Hauts-de-France telle qu’inscrite sur les étendards. Une étude d’objets jusque-là négligés alors que riches d’informations

2020 ◽  
pp. 273-285
Author(s):  
Maryla Laurent ◽  
Iwona H. Pugacewicz
Keyword(s):  
Subject Matter ◽  
Social Life ◽  
Scientific Literature ◽  
The State ◽  
Northern France ◽  
Immigrant Identity ◽  
History Of ◽  
The Subject ◽  
State Of Research

The authors have considered the topic, rarely mentioned in the scientific literature, which are the inscriptions and symbols placed on polonical banners. A three-volume dissertation by Monika Salmon-Siama, entitled Vexillological heritage of the Polish immigration in northern France (1919-2018), turned out to be a contributing factor to this kind of scientific digression. In the introduction, they analyzed the state of research on Polish emigration, settled in northern France, indicating the main reasons for their poor representativeness in comparison with the entire emigre history of the Polish diaspora. Referring to the proper vexological studies, they brought closer the richness of sources that we deal with in the discussed region, and then showed the complexity of this type of bibliological-semiotic research. Taking up the subject matter from the Westphalian-French borderline, inevitably, after M. Salmon Siama, they showed aesthetic and axiological values, including patriotic values, a group of symbols and inscriptions discussed, and in turn showed the durability of the Polish immigrant identity of subsequent generations living in northern France. The article is also an attempt to show the reader the diversity and richness of organizational and social life over almost a century, introduces the mentality and customs of the Polish Diaspora, and shows the underestimated role of the Polish banner.  

mySmartCheck, a Digital Intervention to Promote Skin Self-examination Among Individuals Diagnosed With or at Risk for Melanoma: A Randomized Clinical Trial

2021 ◽  
Author(s):  
Sharon L Manne ◽  
Michael A Marchetti ◽  
Deborah A Kashy ◽  
Carolyn J Heckman ◽  
Lee M Ritterband ◽  
...  
Keyword(s):  
Positive Impact ◽  
Body Part ◽  
The Body ◽  
Clinical Settings ◽  
Body Parts ◽  
Increased Risk ◽  
History Of ◽  
Self Examination ◽  
To Receive

Abstract Background Regular skin self-examination (SSE) reduces melanoma mortality but is not often conducted. Purpose To promote SSE performance in individuals at increased risk for melanoma. Methods One hundred sixteen individuals at heightened risk for development of melanoma (i.e., personal/family history of melanoma, high-risk mole phenotype) who did not conduct a thorough SSE during in the prior 3 months were randomly assigned to receive either an automated internet-based intervention (mySmartCheck) or usual care (UC). One hundred sixteen participants completed surveys before random assignment and 99 completed the follow-up survey 13-weeks afterward. The primary outcome was participant self-reported examination (SSE) of all 15 parts of the body in the last 3 months. Secondary outcomes were SSE of any part of the body in the last 3 months and number of body parts examined during the last SSE. Results More mySmartCheck participants examined all 15 body parts (32.6% vs. 7.1%, p = .001). More individuals in mySmartCheck reported conducting SSE on any body part than those in UC (81.4% vs. 62.5%, p = .04). Effect sizes were large (d = 1.19 all 15 body parts) to moderate (d = 0.55 for any body part). mySmartCheck participants examined more body areas than UC participants (12.7 vs. 10.3, p = 0.003) during the last SSE. Participants in mySmartCheck reported higher levels of knowledge of suspicious lesions, SSE benefits, SSE self-efficacy, and planning for SSE, and lower SSE barriers, than those assigned to UC. Conclusions mySmartCheck had a significant positive impact on SSE performance and behaviors. Additional research with a larger sample size, a longer follow-up, and more varied clinical settings is needed. Trial Registration ClinicalTrials.gov registration # NCT03725449 (https://clinicaltrials.gov/ct2/show/NCT03725449).

scholarly journals How Did COVID-19 Affect Suicidality? Data from a Multicentric Study in Lombardy

2021 ◽  
Vol 10 (11) ◽  
pp. 2410
Author(s):  
Camilla Gesi ◽  
Federico Grasso ◽  
Filippo Dragogna ◽  
Marco Vercesi ◽  
Silvia Paletta ◽  
...  
Keyword(s):  
Psychiatric Treatment ◽  
Retrospective Chart Review ◽  
Time Frame ◽  
Emergency Rooms ◽  
Multicentric Study ◽  
Priority Level ◽  
History Of ◽  
To Receive ◽  
Free Women ◽  
Drug Free

The aim of the study was to describe the characteristics of subjects accessing the emergency rooms for suicidal behavior during the first epidemic wave of COVID-19 in three Emergency Departments (EDs) in Lombardy (Italy). A retrospective chart review was conducted for the period 8 March–3 June 2020, and during the same time frame in 2019. For all subjects accessing for suicidality, socio-demographic and clinical data were collected and compared between the two years. The proportion of subjects accessing for suicidality was significantly higher in 2020 than in 2019 (13.0 vs. 17.2%, p = 0.03). No differences between the two years were found for sex, triage priority level, history of substance abuse, factor triggering suicidality and discharge diagnosis. During 2020 a greater proportion of subjects did not show any mental disorders and were psychotropic drug-free. Women were more likely than men to receive inpatient psychiatric treatment, while men were more likely to be discharged with a diagnosis of acute alcohol/drug intoxication. Our study provides hints for managing suicidal behaviors during the still ongoing emergency and may be primary ground for further studies on suicidality in the course of or after massive infectious outbreaks.

A 200-Year History of the Study of Childhood Language Disorders of Unknown Origin: Changes in Terminology

2020 ◽  
Vol 5 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Laurence B. Leonard
Keyword(s):  
Language Impairment ◽  
Specific Language Impairment ◽  
Scientific Literature ◽  
Language Disorder ◽  
Language Disorders ◽  
Unknown Origin ◽  
Developmental Language Disorder ◽  
The Past ◽  
History Of ◽  
The Many

Purpose The current “specific language impairment” and “developmental language disorder” discussion might lead to important changes in how we refer to children with language disorders of unknown origin. The field has seen other changes in terminology. This article reviews many of these changes. Method A literature review of previous clinical labels was conducted, and possible reasons for the changes in labels were identified. Results References to children with significant yet unexplained deficits in language ability have been part of the scientific literature since, at least, the early 1800s. Terms have changed from those with a neurological emphasis to those that do not imply a cause for the language disorder. Diagnostic criteria have become more explicit but have become, at certain points, too narrow to represent the wider range of children with language disorders of unknown origin. Conclusions The field was not well served by the many changes in terminology that have transpired in the past. A new label at this point must be accompanied by strong efforts to recruit its adoption by clinical speech-language pathologists and the general public.

Suicidal Behavior in German Adolescents

2015 ◽  
Vol 43 (1) ◽  
pp. 39-45 ◽  
Author(s):  
Joana Straub ◽  
Ferdinand Keller ◽  
Nina Sproeber ◽  
Michael G. Koelch ◽  
Paul L. Plener
Keyword(s):  
Suicidal Behavior ◽  
Suicide Attempts ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Present Sample ◽  
Manic Symptoms ◽  
Symptoms Of Depression ◽  
Adolescent Sample ◽  
History Of ◽  
Sum Scores

Objective: Research in adults has identified an association between bipolar disorder and suicidal behavior. This relationship, however, has been insufficiently investigated in adolescents to date. Methods: 1,117 adolescents from 13 German schools (mean age = 14.83, SD = .63; 52.7% females) completed an extended German version of the Center for Epidemiological Studies Depression Scale (CES-D), which assesses depressive and manic symptoms during the last week, as well as the Self-Harm Behavior Questionnaire (SHBQ) for the assessment of lifetime suicidal behavior. Results: In the present sample 39.4% of the girls and 23.1% of the boys reported lifetime suicidal thoughts and 7.1% of the girls as well as 3.9% of the boys a lifetime history of suicide attempts. 18.7% of the adolescent sample revealed elevated symptoms of depression and 9% elevated levels of mania symptoms. Elevated sum scores of depression and mania were associated with a higher number of suicidal ideations and suicide attempts. A block-wise regression analysis revealed that sum scores of depression and mania predicted suicidal ideations best. Concerning suicide attempts, the best predictors were age as well as depression and mania sum scores. Conclusions: Suicidal behavior was reported more often when adolescents demonstrate symptoms of mania as well as symptoms of depression than when they demonstrate only depressive symptoms. The presence of bipolar symptoms in adolescents should alert clinicians to the heightened possibility of suicidal behavior.

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