Evaluation of effectiveness of a new combined method of treatment of primary progressive pterygium

2021 ◽  
pp. 221-225
Author(s):  
A.N. Bochkareva ◽  
◽  
V.V. Egorov ◽  
O.V. Kolenko ◽  
G.P. Smoliakova ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Surgical Treatment ◽  
Ultraviolet Irradiation ◽  
Combined Treatment ◽  
Disease Recurrence ◽  
Surgical Removal ◽  
Initial Growth ◽  
Ophthalmological Examination ◽  
Combined Method ◽  
Primary Progressive

Purpose. Evaluation of the effectiveness of the combined method in the surgical treatment of pterygium. Material and methods. There were 30 patients (30 eyes) under observation for primary progressive pterygium. To assess the condition of the ocular surface and the functional effectiveness of the new combined method of treating pterygium, the patients were divided into two groups. The main group consisted of 15 patients (15 eyes) who underwent surgical treatment of the pterygium according to the developed method. The comparison group consisted of 15 patients (15 eyes), who underwent pterygium removal using standard technology. Standard ophthalmological examination included: visometry, autorefractokeratometry, biomicroscopy with fluorescence test. The criteria for evaluating the effectiveness of treatment were: maximally corrected visual acuity; the degree of corneal astigmatism; the presence and degree of turbidity in the operation area; the frequency of relapse. Results. The use of the proposed method of combined treatment of pterygium, including surgical removal with plasty of the amnion in the zone of initial growth in combination with ultraviolet irradiation of the de-epithelialized corneal bed in the postoperative period, leads to the restoration of transparency and the correct shape of the cornea, therefore, and minimization of induced astigmatism, which is accompanied by an increase in functional parameters eyes. Conclusion. The results obtained, the simplicity and availability of the method developed by us allow us to recommend it for wider use in the surgical treatment of pterygium in order to increase the functional, cosmetic effect, surgical rehabilitation and prevention of disease recurrence. Key words: pterygium, combined treatment, visual acuity, ultraviolet irradiation.

scholarly journals The Effect of Pterygium Surgery on Corneal Topography

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
N M Welson ◽  
M M M Samy ◽  
A A Gaafar ◽  
T A Badran
Keyword(s):  
Visual Acuity ◽  
Surgical Treatment ◽  
Corneal Topography ◽  
Surgical Removal ◽  
Significant Difference ◽  
Uncorrected Visual Acuity ◽  
Pterygium Surgery ◽  
The Mean ◽  
Pterygium Excision ◽  
Topographic Astigmatism

Abstract Objective To evaluate the effect of pterygium surgery on corneal topography by comparing wave front analysis before and one month after the surgical treatment. Methodology Fifty eyes of forty-one patients were included in this study. Twenty five male and sixteen female patients seeking pterygium surgery were recruited from the Ophthalmology Department Outpatient Clinic in Sohag Teaching Hospital during the period from July 2017 to May 2018. All eyes underwent pterygium excision with conjunctival autograft. Results In this study we found a highly statistically significant improvement in the mean uncorrected visual acuity from 0.44±0.21SD preoperatively to 0.62±0.18SD postoperatively (p < 0.001) and a highly statistically significant difference in the mean logMAR visual acuity as it was decreased from 0.43±0.28 SD preoperatively to 0.34±0.23 SD postoperatively (p < 0.001). Also, there was a highly statistically significant improvement in mean of manifest refractive astigmatism from -4.08±3.28 SD preoperatively to -1.46±1.40 SD postoperatively (p < 0.001). We also found a highly statistically significant improvement in the mean cycloplegic astigmatism from -4.00±3.01 SD preoperatively to -1.39±1.33 SD postoperatively (p < 0.001) and also there was a highly statistically significant improvement in the mean topographic astigmatism from -5.17±4.08 SD preoperatively to -2.20±2.31 SD postoperatively (p < 0.001). We also found a highly statistically significant improvement in the mean of ISV (Index of Surface Variance) from 76.22±36.86 SD preoperatively to 33.56±15.02 SD post operatively (p < 0.001) and also there was a highly statistically significant improvement in the mean IHD (Index of Height Decentration) from 0.042±0.027SD pre-operatively to 0.023±0.036 SD post operatively. Conclusion There was a highly statistically significant difference in the mean logMAR visual acuity and a highly statistically significant improvement in the mean uncorrected visual acuity. A highly statistically significant improvement in both refractive and topographic astigmatism after one month of the surgery was noted also. Here were also a highly statistically significant improvement in ISV and IHD that indicate improvement after pterygium removal. Recommendations Patient with pterygium that inducing astigmatism will benefit from surgical removal of the pterygium.

scholarly journals Prospects of Chemotherapy for Gastrointestential Stromal Colon Tumours

2020 ◽  
Vol 10 (3) ◽  
pp. 249-253
Author(s):  
A. R. Mukhamediyarov ◽  
L. I. Bashirova ◽  
A. I. Maksyutova ◽  
A. T. Gattarova
Keyword(s):  
Surgical Treatment ◽  
Kinase Inhibitors ◽  
Combined Treatment ◽  
Objective Response ◽  
Symptomatic Treatment ◽  
Objective Evaluation ◽  
The United States ◽  
Surgical Removal ◽  
Gastrointestinal Stromal Tumours ◽  
Initial Stage

Gastrointetinal stromal tumours are the most common primary mesenchymal tumours of the gastrointestinal tract. According to statistical data, the annual incidence of this pathology in Russia comprises 13 patients per 1 million inhabitants, i.e. about 2,000 patients per year on average. In the United States, 3,000–4,000 cases are registered every year. This article discusses general and specific issues associated with morbidity and mortality from gastrointestinal stromal tumours, as well as reasons for the low efficacy of surgical and targeted therapies. Methods for combined treatment of patients with gastrointestinal stromal tumours are proposed. The treatment of such pathologies has evolved with the development of immunohystochemical analytical procedures and therapies against KIT/PDGFRA-specific protooncogenes, as well as the emergence of low-molecular kinase inhibitors. However, the probability of non-recurrence survival can only be increased by complete surgical removal of gastrointestinal stromal colon tumours. In the surgical treatment, three main approaches are defined: the initial stage of treatment, provided that the tumour is resectable and has a small size; surgical treatment after neoadjuvant therapy; symptomatic treatment, so-called ‘debulking surgery’. Adjuvant targeted therapy with Imatinib provides for a high objective response. The use of Imatinib chemotherapy determines the efficacy and radicality of surgical treatment in most cases. In general, the question of treating gastrointestinal stromal colon tumours is still relevant, requiring further research and objective evaluation of all technical and tactical approaches in the context of distant results.

scholarly journals Surgical treatment of retroperitoneal neuroblastoma in a 14-month-old child

2021 ◽  
Vol 25 (1) ◽  
pp. 61-67
Author(s):  
M. N. Sukhov ◽  
A. G. Narbutov ◽  
I. P. Lyvina ◽  
I. A. Bryzzheva ◽  
M. V. Isaeva ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Nursery School ◽  
Disease Recurrence ◽  
Surgical Removal ◽  
Anatomical Location ◽  
Good State ◽  
Staging Systems ◽  
Tumor In Childhood ◽  
The Right

Introduction. Neuroblastoma is the most common malignant embryonic extracranial solid tumor in childhood having a high mortality rate. While treating neuroblastoma, it is extremely important to follow international protocols with their staging systems and groups of risk. Surgical treatment is a compulsory approach, but in some cases it is extremely difficult, and it involves significant risks. However, in some cases, radical removal of the tumor can cure patients without chemotherapy.Material and methods. The article presents a clinical case of 14-month-old child with neuroblastoma of stage 3 and difficult anatomical location after 2 courses of polychemotherapy by NB-2004 protocol. The child had subradical resection of an extensive tumor in the retroperitoneal space and nephrectomy on the right. The authors also describe specific moments during surgery, problems which their faced during child’s treatment as well as follow-up examinations in the postoperative period.Results. Follow-up examinations did not reveal any signs of disease recurrence. Catamnesis lasted for 56 months. The child is in a good state; she is active, attends a nursery school.Conclusion. The discussed case demonstrates that a successful radical surgical removal of neuroblastoma of difficult anatomic location may have good outcomes without adjuvant postoperative therapy.

scholarly journals Optimization of surgical treatment of cataract in patients with diabetes mellitus

2010 ◽  
Vol 13 (2) ◽  
pp. 91-93
Author(s):  
Dmitriy Valentinovich Lipatov ◽  
Timofey Alexandrovich Chistyakov ◽  
Anatoliy Gennad'evich Kuz'min
Keyword(s):  
Visual Acuity ◽  
Surgical Treatment ◽  
Combined Treatment ◽  
Functional Results ◽  
Early Postoperative Period ◽  
Lens Opacity ◽  
Research Centre ◽  
Diabetic Cataract ◽  
Ocular Tissues ◽  
Patients With Diabetes

Aim. To compare different methods for surgical treatment of cataract in patients with diabetes melli-tus (DM) and substantiate the choice of its optimalmodality. Materials and methods. Analysis included data on 209 patients (221 eyes) treated from January 2008 to December 2009 in the Department ofRetinopathy and Ophthalmosurgey, Endocrinological Research Centre. Diabetic cataract was managed using UNIVERSAL-II, LEGACY EVEREST,and INFINITI phacoemulsifiers. Parameters studied included time of ultrasound (US) ex-posure, US power, and retinal characteristics in the earlypostoperative period. In addition, analysis included data on the location of lens opacity in 1047 patients (1897 eyes) with diabetic cataract. Results. Relatively low corrected and uncorrected visual acuity in the early postoperative period was attributable to concomitant DM-related retinalpathology. Analysis of lenticular opacity showed that it in the first place affected collagen fibers beneath the posterior capsule. The use of torsional USin INFINITI for cataract phacoemulsification produced almost 4-fold reduction in the exposure time of ocular tissues. As a result, the postoperativeoedema was significantly smaller than in patients undergoing combined treatment (AQUALASE hydromonitoring and OZIL ultrasound system). Conclusion. Combination of ultrasound and hydromonitoring phacoemulsification for the treatment of cataract in DM patients reduces exposure timeof ocular tissues and postoperative oedema which creates prerequisites for faster recovery of visual acuity after surgery. Functional results of surgicaltreatment of diabetic cataract can be further improved by early diagnosis of lens opacity and the use of US and hydromonitoring phacoemulsificationtechniques.

New approach to surgical treatment of primary progressive pterygium

2021 ◽  
pp. 13-17
Author(s):  
A.N. Bochkareva ◽  
◽  
O.V. Kolenko ◽  
V.V. Egorov ◽  
G.P. Smoliakova ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Disease Index ◽  
Tear Fluid ◽  
Control Group ◽  
Initial Growth ◽  
Ocular Surface Disease Index ◽  
New Approach ◽  
Primary Progressive ◽  
Recurrent Pterygium

Purpose. To evaluate effectiveness of new method of barrier amnioplasty in surgical treatment of primary progressive pterygium. Material and methods. The study included 64 patients (64 eyes) with primary progressive pterygium. All patients were divided into two groups depending on method of barrier amnioplasty. The main group consisted of 32 people (32 eyes) who underwent barrier amnioplasty in the area of initial growth of pterygium. The control group consisted of 32 patients (32 eyes) who underwent barrier amnioplasty in the limbus area. The main criterions for clinical efficacy of surgical treatment of pterygium was dynamics of the wound process, the Ocular Surface Disease Index (OSDI) and the osmolarity of the tear fluid in the compared groups. Also, after 1 year, the frequency of pterygium recurrence was assessed. In addition to standard ophthalmological examinations, special methods were used in the work: determination of the osmolarity of the tear fluid, pH of tears, cytological assessment of the wound process, and also assessed the OSDI. Results. The results of pH-metric, osmometric, cytological studies have provided evidence of the ability of the anatomical and topographic approach described by us to positively influence the course of inflammatory and reparative processes in the operation area, preventing the development of recurrent pterygium and cicatricial deformities. Conclusion. A new effective method of surgical treatment of primary progressive pterygium, including moving the area of the barrier amnioplasty from the limbus area to the area of initial growth of blood vessels of pterygium - the area of the lunate fold, has been developed and introduced into clinical practice. Key words: pterygium, inflammatory and reparative processes, recurrence.

scholarly journals A retrospective analysis of the results of surgical treatment of large macular holes

2018 ◽  
Vol 99 (2) ◽  
pp. 341-344
Author(s):  
A N Samoylov ◽  
G A Fazleeva ◽  
T R Khaybrakhmanov ◽  
P A Samoylova ◽  
M A Fazleeva
Keyword(s):  
Visual Acuity ◽  
Surgical Treatment ◽  
Retrospective Analysis ◽  
Ophthalmological Examination ◽  
Modified Technique ◽  
Complete Closure ◽  
Macular Holes ◽  
Idiopathic Macular Holes ◽  
Group 2 ◽  
Group 1

Aim. A retrospective analysis of the results of surgical treatment of large idiopathic macular holes depending on the technique of surgical intervention. Methods. The results of surgical treatment of 60 patients (60 eyes) with idiopathic macular holes with a diameter of more than 800 μm were studied in the Republican clinical ophthalmology hospital of Kazan. The average age of the patients was 66.2±5.37 (61-74) years. The patients underwent complex ophthalmological examination before the surgery and 10 days and 1 month after the surgery, including visometry, tonometry and optical coherence tomography. Patients were divided into two groups (30 subjects each), comparable in clinical and epidemiological parameters: group 1 - standard surgical tactics, group 2 - surgical treatment according to the method proposed by professor A.N. Samoylov. Visual acuity with correction before surgery in group 1 was 0.11±0.05, in group 2 - 0.12±0.06. Results. Ten days after the surgery, group 1 had anatomical closure in 23 (76.7%) patients, anatomical result was not achieved in 7 (23.3%) patients. In group 2, complete closure of the rupture was achieved in 27 (90.0%) patients, incomplete - in 3 (10.0%) patients. In 1 month in group 1, complete closure of the macular rupture was observed in 22 (73.3%) patients, in 8 (26.7%) patients the result was not achieved. In group 2, complete closure of the rupture was determined in 28 (93.3%) patients, incomplete closure - in 2 (6.7%) patients. Visual acuity 1 month after the surgery in group 1 was 0.15±0.08, and in group 2 - 0.32±0.11 (p <0.05). Conclusion. Surgical treatment of large idiopathic macular holes according to the modified technique of the inverted internal limiting membrane flap proposed by professor A.N. Samoylov, provides better anatomical and functional results in comparison with the standard technique (p <0.05).

scholarly journals Innovative approach to barrier amnioplasty in surgical treatment of primary progressive pterygium

2020 ◽  
Vol 12 (4) ◽  
pp. 13-21
Author(s):  
Anna N. Bochkareva ◽  
Victor V. Egorov ◽  
Galina P. Smoliakova ◽  
Alexey D. Pilipenko ◽  
Pavel A. Banshchikov
Keyword(s):  
Visual Acuity ◽  
Surgical Treatment ◽  
Early Postoperative Period ◽  
Corneal Astigmatism ◽  
Control Group ◽  
Inflammatory Reactions ◽  
Primary Progressive ◽  
Limbal Area ◽  
Conjunctival Inflammation ◽  
Special Examination

The aim is to evaluate the efficacy of new method of barrier amnioplasty in surgical treatment of primary progressive pterygium. Materials and methods. 40 patients (40 eyes) with primary progressive pterygium, divided into two groups depending on surgical features of barrier amnionoplasty: in the main group (20 patients), plastic surgery was carried out in the semilunar fold area; in the control group (20 patients) in the limbal area. All patients underwent special examination: tear pH measurement and cytological evaluation of the cellular composition from the wound surface. The treatment efficacy was evaluated: in the early postoperative period by the timing of conjunctival inflammation disappearance, corneal epithelialization and vitalization of the amnion; after 1 year according to the state of the limbus, cornea, visual acuity, degree of corneal astigmatism. Results and conclusions. The use of amnioplasty method in the area of semilunar fold developed and implemented by us in clinical practice showed high efficacy: time reduction in local cellular inflammatory reactions in the cytological composition of swabs and scrapings and postoperative inflammation of ocular surface, which led to shortening of periods of corneal epithelization by 1.7 times and vitalization of the amnion by 1.5 times. Uncomplicated postoperative course of inflammatory-regenerative reactions allows avoiding the pterygium recurrence and causes reduction of the degree of corneal astigmatism and visual acuity increase.

Surgical treatment of transmissible venereal tumor (sticker sarcoma)

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Bougherara Hithem ◽  
Boukhechem Saïd ◽  
Aguezlane Abdelaziz ◽  
Benelhadj Khouloud ◽  
Aissi Adel
Keyword(s):  
Surgical Treatment ◽  
Cancer Cells ◽  
Treatment Method ◽  
High Rate ◽  
Surgical Removal ◽  
Characteristic Appearance ◽  
Recurrent Tumors ◽  
External Genital Organs

Background: Sticker sarcoma, also called venereal sarcoma or venereal lymphosarcomatosis, is a tumor of the external genital organs in females and males. In male animals the penis and foreskin (prepuce) are affected, in the female, it happens in vagina (vagina) and labia (vulva). The diagnosis of sticker sarcoma is based on the chronic discharge, the typical locations and the characteristic appearance of the tumor. Methods: We have relied on the treatment method on the complete surgical removal of all cancer cells that we can access. Results: After surgery, we notice recurrent tumors about six months after surgical treatment, indicating the need for other treatments in addition to surgery. Conclusion: Although spontaneous regressions of sticker sarcoma are documented (with permanent immunity), chemotherapy is the treatment of choice today. Irradiation should also be effective. If the tumor is only removed surgically, there is a high rate of recurrence, and this is what happened with the case that we treated, as the tumor reappeared after less than six months.

Hemangiomatosis of the greater omentum – a case report

2019 ◽  
Vol 98 (4) ◽  
pp. 178-180
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Histological Examination ◽  
Case Reports ◽  
Greater Omentum ◽  
Surgical Removal ◽  
Consumption Coagulopathy ◽  
Cavernous Hemangiomas ◽  
Mesodermal Origin ◽  
Benign Tumours

Cavernous hemangiomas are benign tumours of mesodermal origin. Even though various localizations of hemangioma have been described in the literature, its occurrence in the greater omentum is very rare. Only symptomatic hemangiomas are indicated for surgical treatment. There are case reports presenting resection or surgical removal of the greater omentum with hemangioma because of mechanical syndrome, consumption coagulopathy, bleeding, infection or suspicion of a malignancy. This article presents a case report of a patient operated on for a suspicion of carcinomatosis of the greater omentum. Histological examination found hemangiomatosis in the resected greater omentum.

scholarly journals A case of Gayet-Wernicke encephalopathy with misleading symptoms

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Mohamed Hadbi ◽  
Dalila Benalakma ◽  
Nadia Fellah
Keyword(s):  
Visual Acuity ◽  
Hyperemesis Gravidarum ◽  
Neurological Complication ◽  
Vitamin Supplementation ◽  
Motor Deficit ◽  
Ophthalmological Examination ◽  
Cerebral Mri ◽  
Sensory Motor ◽  
Brain Stroke ◽  
Decrease In Visual Acuity

Abstract Background The dramatic evolution of incoercible vomiting in pregnancy is at the origin of a rare and serious neurological complication known as EGW; its symptomatology is polymorphic posing a diagnostic problem. MRI is the test of choice for screening. Early vitamin supplementation is essential to improve the maternal-fetal prognosis. Case presentation A 35-year-old parturient, G5P1, without particular pathological history presented incoercible vomiting at 8 weeks, which led to dehydration, undernutrition, and impairment of general condition. Neurological signs: headaches, confused scored at 14 on the Glasgow scale, amnesia, a cerebellar syndrome, sensory-motor deficit. Ophthalmological examination revealed: edema in the eye fundus, a decrease in visual acuity, nystagmus, and ophthalmoplegia. The biological analysis showed moderate hepatic cytolysis. Given the polymorphic neurological symptomatology presented by our parturient, several differential diagnoses were evoked: intracranial hypertension (headache - vomiting - decrease in visual acuity - papillary edema), brain stroke (sensory-motor deficit, ground “pregnancy”), deficit in vitamin B12 (sensory-motor deficit, confusion, memory impairment), and GWE (nystagmus-confusion-ataxia). Cerebral MRI has allowed us to establish the diagnosis of GWE. Conclusion All pregnant with severe hyperemesis gravidarum should be supplemented with thiamine prior to glucose administration to prevent and improve the prognosis of GWE.

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