Bacterial conjunctivitis (literature review)

2021 ◽  
pp. 87-90
Author(s):  
A.E. Babushkin ◽  
◽  
N.E. Shrvchuk ◽  
Keyword(s):  
Literature Review ◽  
Antibiotic Therapy ◽  
Key Words ◽  
Wide Spectrum ◽  
Comprehensive Treatment ◽  
Bacterial Conjunctivitis ◽  
Eye Infections ◽  
Gram Negative ◽  
First Choice ◽  
Causative Agents

The article is devoted to bacterial conjunctivitis. The review of scientific works on this problem presents the clinic, diagnosis and comprehensive treatment of this ophthalmopathology. At the same time, much attention is paid to antibiotic therapy of bacterial conjunctivitis. A special place in it is occupied by antibiotic fluoroquinolones, which have a wide spectrum of action, including gram-positive and gram-negative causative agents of eye infections, and can be considered the drugs of first choice in bacterial conjunctivitis, especially resistant to other antibiotics. Key words: bacterial conjunctivitis, clinic, diagnosis, treatment.

Empirical antibiotic therapy of complicated skin and soft tissue infections in dermatological practice

2011 ◽  
Vol 152 (7) ◽  
pp. 252-258
Author(s):  
Andrea Magyar ◽  
Edina Garaczi ◽  
Edit Hajdú ◽  
Lajos Kemény
Keyword(s):  
Soft Tissue ◽  
Antibiotic Therapy ◽  
Streptococcus Pyogenes ◽  
Anaerobic Bacteria ◽  
Empirical Therapy ◽  
Soft Tissue Infections ◽  
Empirical Antibiotic Therapy ◽  
Gram Negative ◽  
First Choice ◽  
Complicated Skin

Erysipelas is an acute bacterial infection of the skin predominantly caused by Streptococcus pyogenes. According to the international classification complicated erysipelas belongs to the complicated skin and soft tissue infections. Complicated infections are defined as severe skin involvement or when the infection occurs in compromised hosts. These infections frequently involve Gram-negative bacilli and anaerobic bacteria. Aims: The aim of this study was to compare the efficacy of the empirical antibiotic therapy for the patients who were admitted to the Department of Dermatology and Allergology, University of Szeged. Methods: The empirical therapy was started according to a previously determined protocol. The data of 158 patients with complicated skin and soft tissue infections were analyzed and the microbiology culture specimens and the isolates were also examined. Results and conclusions: The results show that penicillin is the first choice for the treatment of erysipelas. However, the complicated skin and soft tissue infections require broad-spectrum antibiotics. Orv. Hetil., 2011, 152, 252–258.

Neuroprotective therapy for glaucoma (literature review)

2021 ◽  
pp. 61-64
Author(s):  
O.I. Orenburkina ◽  
◽  
A.E. Babushkin ◽  
E.N. Matyukhina ◽  
◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Drug Therapy ◽  
Literature Review ◽  
Key Words ◽  
Neuroprotective Effect ◽  
Comprehensive Treatment ◽  
Physical Factors ◽  
Therapeutic Action ◽  
Neuroprotective Therapy ◽  
Key Words Glaucoma

This literature review presents data on neuroprotection in glaucoma. In neuroprotective therapy, it is desirable to use a comprehensive treatment that includes drugs of various pharmacological groups acting on different pathogenetic links of glaucoma optical neuropathy. One of the most promising areas of neuroprotection is the simultaneous combined effect of various physical factors (with mutual potency of their therapeutic action) and drug therapy, which increases the neuroprotective effect. However, treatment should be performed against the background of absolutely normalized intraocular pressure. Key words: glaucoma, glaucoma optical neuropathy, neuroprotection, drug therapy, normalized intraocular pressure.

scholarly journals Neonatal Sepsis in A Tertiary Care Hospital: Evaluation of Causative Agents and Antimicrobial Susceptibilities

2013 ◽  
Vol 37 (1) ◽  
pp. 14-17
Author(s):  
Begum Sharifun Nahar ◽  
Syeda Afroza ◽  
Sunirmol Roy ◽  
Nurun Nahar ◽  
Tarok Nath Kundu
Keyword(s):  
Antibiotic Therapy ◽  
Neonatal Sepsis ◽  
Neonatal Care ◽  
Gram Positive ◽  
Gram Negative ◽  
Medical College ◽  
Causative Agents ◽  
The Common ◽  
Neonatal Care Unit ◽  
Gram Negative Organisms

Background: Neonatal sepsis is an important issue with a high morbidity and mortality rate in spite of new advances in antibiotic therapy. Identifying the causative agents and their antibiotic sensitivity in a neonatal care unit (NCU) helps the physician to choose the most appropriate antibiotic therapy. Objectives: This study was aimed to find out the etiological agent and antibiotic susceptibilities in newborn with culture positive sepsis. Methodology: This was a cross sectional study carried out in the neonatal care unit (NCU) of Sir Salimullah Medical College Mitford Hospital (SSMC) from June 2010 to May 2011. Seventy five neonates both preterm and term with culture proven sepsis were analyzed from admitted sick newborn to find out their etiology and antimicrobial sensitivity pattern. Blood culture was done in the department of Microbiology of the same medical college hospital. Results: In this study, out of 75 cases, early onset sepsis was observed in 55(73.33%) cases. Whereas late onset sepsis was in 20(26.66%) cases. Gram negative organisms were isolated in 59 (78%) of 75 cases. Pseudomonas aeroginosa 27 (46.55%), E Coli 15(25.86%) and Serratia 8 (13.79%) were the common microbes. Coagulase negative staphylococcus (CONS) was 10 (62%), followed by Staphylococcus aureus 6 (38%) were the major Gram positive isolates. Gram negative isolates were sensitive to Imipenem, Ceftazidime and Ciprofloxacin whereas 80 % gram positive isolates were sensitive to Amikacin. Conclusion : It was observed from this study that gram negative organisms like pseudomonas aeroginosa and E.coli were the common organisms for neonatal sepsis in hospitalized neonates and imipenem was the most sensitive drug against gram - ve septicaemia. DOI: http://dx.doi.org/10.3329/bjch.v37i1.15346 BANGLADESH J CHILD HEALTH 2013; VOL 37 (1) : 14-17

Current antibiotic therapy of endo-perio lesions with secondary endodontic involvement

2021 ◽  
Vol 26 (2) ◽  
pp. 105-113
Author(s):  
L. Yu. Orekhova ◽  
V. G. Atrushkevitch ◽  
E. S. Loboda ◽  
V. Yu. Vashneva ◽  
A. A. Petrov
Keyword(s):  
Antibiotic Therapy ◽  
Antibiotic Sensitivity ◽  
Endodontic Treatment ◽  
Comprehensive Treatment ◽  
Sensitivity Testing ◽  
Microbiological Test ◽  
Systemic Antibiotic ◽  
Periodontal Inflammation ◽  
Systemic Antibiotic Therapy ◽  
Group 2

Relevance. Successful treatment of endo-perio lesions depends on the thorough clinical assessment, accurate diagnosis and structural approach to the planning of periodontal and endodontic treatment. Aim – to provide clinical and laboratory evidence about the effectiveness of ciprofloxacin-and-tinidazole-containing antibiotic in the comprehensive treatment of endo-perio lesions with a primary periodontal disease which secondarily affects the pulp.Materials and methods. We examined 29 patients aged from 35 to 50 (mean age 42.3±3.21) with class II endo-perio lesions according to P. Eickholz classification. The patients were randomly divided into 2 groups. All patients had comprehensive periodontal and endodontic treatment with (Group 2) and without (Group 1) antibiotic therapy. The clinical and paraclinical examination included determination of such indices as OHI-s, SL, PMA, SBI, as well as Doppler ultrasound, EPT, CBCT, microbiological test of the discharge from periodontal pockets and root canal system. We selected the systemic antibiotic after the antibiotic sensitivity testing.Results. Comprehensive treatment of endo-perio lesions, which included systemic antibiotic therapy with ciprofloxacin and tinidazole, effectively arrested the inflammation in the periodontium and pulp beginning from the 7th day of use.Conclusion. Cifran ST, a combination broad-spectrum antibiotic, helps reduce periodontal inflammation by effectively eliminating microbiota in the root canals and periodontal pockets in patients with moderate or severe chronic generalized periodontitis. 

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