An interventional study to assess the quality of life in abnormal uterine bleeding in a medical college teaching hospital

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Manikanth BN ◽  
Konudula Revathi Sindhu ◽  
Juveria Banu ◽  
Jennilyn James ◽  
Sheba Baby John ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Functioning ◽  
College Teaching ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Age Group ◽  
Medical College ◽  
Sf 36 ◽  
The Impact

Abnormal uterine bleeding has a major impact on a woman's quality of life. This study aimed to improve quality of life rather than focusing on the amount of blood loss and also to understand how it affects their quality of life. Patients demographic and therapeutic details were collected (name, age, sex . 80 patients suffering from abnormal uterine bleeding are taken from medical college teaching hospital. The quality of life in patients with abnormal uterine bleeding is assessed using SF 36 . Then up is done for quality of life in patients with abnormal uterine bleeding using SF 36 . This study showed that before counseling the age group of 51-60 years have less physical functioning when compare to other groups and BMI of 0<18.5 have more improvement is seen in physical functioning after . The age group of 21-30 years has less limitation due physical functioning when compare to other groups. Before the age group of 21-30 years felt more pain, was decreased after . Regarding the Quality of life, the impact of AUB encompasses all aspects of QOL with eight health domains measured by SF-36 result shows 32% of the patients quality of life is poorest. Provided to the patients proved to be beneficial in improving their health related QOL. This leads to a conclusion that the public as well as need to increase awareness of the impact of this common benign gynecologic disorder.

Quality of life during the first 6 months of interferon-b treatment in patients with MS

2000 ◽  
Vol 6 (5) ◽  
pp. 338-342
Author(s):  
J HA Arnoldus ◽  
J Killestein ◽  
L EMA Pfennings ◽  
B Jelles ◽  
B MJ Uitdehaag ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Side Effects ◽  
Physical Functioning ◽  
Bodily Pain ◽  
Significant Linear Trend ◽  
Role Physical ◽  
Sf 36 ◽  
The Impact

Objectives: To determine the quality of life (QoL) of MS patients during the initial 6 months of treatment with interferon-b (IFN-b). Furthermore, to determine whether changes in QoL relate to disability, emotional state, therapeutic expectations or side effect profile. Background: IFN-b has been shown to have beneficial effects on the course of MS. Since the aim of IFN-b treatment is not to cure but to slow down the disease it is important to know how this treatment affects QoL. Surprisingly, the impact of treatment with IFN-b on QoL measures has not been extensively studied so far. Methods: Case report documentation, including EDSS, SF-36 and MADRAS scores, of 51 relapsing-remitting MS patients treated with IFN-b was obtained at baseline and at months 1, 3 and 6. Patients also filled in a form about their expectations of therapy and a questionnaire on side effects. Results: During treatment there was a significant linear trend indicating improvement in the role-physical functioning (RPF) scale of the SF-36 (F1,50=4.9, P=0.032). A transient decrease at month 1 was found in the scale for bodily pain, indicating more experienced pain (F1,50=19.8, P50.001). Subgroup analysis showed that patients with most depressive symptoms on the MADRAS at baseline contributed most to the increase in RPF scores over time (F1,24=5,6 P=0.026). Furthermore, we found associations between adverse event scores and several domains of QoL. Conclusions: Our findings suggest that IFN-b therapy has an impact on QoL of MS patients in that it improves role-physical functioning and transiently worsens experienced bodily pain. QoL during treatment with IFN-b is influenced by depressive symptoms at baseline as well as by treatment-associated side-effects.

scholarly journals The Impact of acne on the quality of life of the patients attending dermatology outpatient department at Nobel Medical College Teaching Hospital

2018 ◽  
Vol 7 (1) ◽  
pp. 45-49
Author(s):  
Manish Pradhan ◽  
Chandra Bhal Jha ◽  
Dipa Rai
Keyword(s):  
Quality Of Life ◽  
Teaching Hospital ◽  
College Teaching ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Medical College ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Background: Acne is a very common distressing skin condition that affects multiple aspects of quality of life of an individual. It has been illustrated that acne have tremendous effect on an individual’s self-image and impacts his or her quality of life. The extent of burden of the disease experienced by the patients seems to be underestimated by the whole medical fraternity. The aim of the study is to determine the health related quality of life impairment in acne patients using CADI and to identify various variables that increase the patients’ susceptibility for quality of life impairment. Subjects and Methods: This is a hospital based, cross sectional study conducted in the Department of Dermatology, Nobel Medical College Teaching Hospital from Jan 2017 to December 2017.A total of 202 acne patients were evaluated with CADI. Clinical characteristics were recorded after history and clinical examination. Results: Out of total 202 patients enrolled, 56.4% of patient scored a CADI score of (5-9) indicating moderate quality of life impairment and 15.3% of patient scored a CADI score of 10 or more indicating severe quality of life impairment. The mean CADI score was 6.82 ± 2.75. There was positive correlation between the CADI score and impact on quality of life with grade of acne, which was statistically significant (p<0.001). Conclusion: Acne is a common skin disease with tremendous adverse effect on the patient’s health related quality of life. Patients are affected both physically and mentally with this condition. Journal of Nobel Medical College Volume 7, Number 1, Issue 12, January-June 2018, Page: 45-49 

scholarly journals Mastectomy versus conservative surgical treatment: the impact on the quality of life of women with breast cancer

2010 ◽  
Vol 10 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Daniela Francescato Veiga ◽  
Fabíola Soares Moreira Campos ◽  
Leda Marques Ribeiro ◽  
Ivanildo Archangelo Junior ◽  
Joel Veiga Filho ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Functioning ◽  
Negative Impact ◽  
Young Patients ◽  
Conservative Surgery ◽  
Sf 36 ◽  
Significant Difference ◽  
The Impact

OBJECTIVES: to compare the impact of mastectomy and conservative surgery on the quality of life of patients with breast cancer. METHODS: an assessment was made of the quality of life of patients undergoing mastectomy or segmentary mastectomy, at the Pouso Alegre Clinical Hospital, in the Brazilian State of Minas Gerais, using SF-36. The patients were grouped by age (<50 years and >50 years) and years of schooling (<8 years and >8 years). The Mann-Whitney test was used to compare the groups with regard to the age and schooling domains of SF-36. RESULTS: a significant difference between the two groups was found in the domains of "physical functioning" (p=0.04) and "pain" (p=0.01): with the patients undergoing a mastectomy registering the worst scores. Young patients who had undergone a mastectomy displayed the worst quality of life in terms of "physical functioning" (p=0.03), "pain" (p=0.01) and "social functioning" (p=0.01); those undergoing conservative surgery aged over 50 years scored worst on "role emotional" (p=0.05). Patients undergoing a mastectomy with lower levels of schooling scored lower in "physical functioning" (p=0.01), "role physical" (p=0.05) and "pain" (p=0.05). Among those who had attended school for more than eight years, those having undergone a mastectomy scored less in the "pain" domain (p=0.04). CONCLUSIONS: patients who had undergone a mastectomy had worse results in the physical component of the evaluation of quality of life and this negative impact was more strongly felt among younger patients and those with lower levels of schooling.

scholarly journals Evidence-Based Minireview: Abnormal uterine bleeding in users of rivaroxaban and apixaban

Hematology ◽  
2020 ◽  
Vol 2020 (1) ◽  
pp. 538-541
Author(s):  
Amanda E. Jacobson-Kelly ◽  
Bethany T. Samuelson Bannow
Keyword(s):  
Quality Of Life ◽  
Observational Studies ◽  
Oral Anticoagulants ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Evidence Based ◽  
Substantial Impact ◽  
Menstruating Women ◽  
The Impact

Abstract Up to two-thirds of menstruating women experience abnormal uterine bleeding (AUB) when treated with oral anticoagulants. However, the true prevalence of AUB for specific agents remains uncertain, as many of these episodes, while interfering significantly with quality of life and overall health, are not captured by definitions of major bleeding (MB) or clinically relevant nonmajor bleeding (CRNMB) used in clinical trials. A 2017 systematic review determined that women taking rivaroxaban, but not edoxaban or apixaban, had a twofold higher risk of AUB than women taking warfarin. Since then, new data have become available from extension trials, cancer-associated venous thromboembolism trials, pediatric trials, and a few observational studies specifically examining AUB as an outcome. Reported rates of uterine CRNMB were low (around 1%) and similar for rivaroxaban and apixaban in all these studies, and no episodes of uterine bleeding meeting MB criteria were reported. Rates of AUB not meeting MB or CRNMB criteria were much higher, affecting up to 50% of women on rivaroxaban. Only 1 such study included women on apixaban, and no AUB was reported. In pediatric trials, 19% of girls experienced menorrhagia when treated with rivaroxaban. In conclusion, rates of uterine MB and CRNMB were low in all studies, but rates of other types of AUB not meeting these criteria ranged from 15.8% to 50%. We conclude that AUB is underreported due to the limitations of MB/CRNMB criteria despite its substantial impact on quality of life. We urge future investigators to include broader definitions of AUB to better capture the impact of this outcome in menstruating women treated with oral anticoagulants.

Vibration disease: quality of life

2020 ◽  
pp. 24-31
Author(s):  
Sergey Babanov ◽  
Nataliya Tatarovskaya
Keyword(s):  
Quality Of Life ◽  
Physical Functioning ◽  
The Body ◽  
Systemic Effects ◽  
Local Vibration ◽  
Vibration Disease ◽  
Sf 36 ◽  
The Impact

The article presents data on the impact of vibration disease on the quality of life of patients. The main changes in the quality of life parameters of patients based on the results of the study using the SF-36 questionnaire are described. The quality of life of patients with various types of vibration disease is compared. It is established that industrial vibration (both General and local) in addition to the classical changes characteristic of vibration disease from exposure to local vibration (WBL), vibration disease from exposure to vibration (VBOW) first and second degrees (vascular, neurological) substantially violates the quality of life of patients, with the most pronounced changes are characteristic for WBOW, which confirms the systemic effects of vibration and its effects on the body working. The quality of life of sick WIDOWS is significantly reduced, although significant differences are observed only on the scales of «physical functioning» and «physical component of health».

scholarly journals Health related quality of life in COVID-19 survivors discharged from acute hospitals: results of a short-form 36-item survey

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 282
Author(s):  
Alessia Saverino ◽  
Eva Zsirai ◽  
Raphael Sonabend ◽  
Lorenza Gaggero ◽  
Isabella Cevasco ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Functioning ◽  
Short Form ◽  
Health Related Quality ◽  
Short Form 36 ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Background: Health-related quality of life (HRQL) is important for evaluating the impact of a disease in the longer term across the physical and psychological domains of human functioning. The aim of this study is to evaluate HRQL in COVID-19 survivors in Italy using the short form 36-items questionnaire (SF-36). Methods: This is an observational study involving adults discharged home following a coronavirus disease 2019 (COVID-19)-related hospital admission. Baseline demographic and clinical data including the Cumulative Illness Rating Scale (CIRS) and the Hospital Anxiety and Depression Scale (HADS) were collected. The validated Italian version of SF-36 was administered cross-sectionally. The SF-36 contains eight scales measuring limitations in physical and social functioning, the impact on roles and activities, fatigue, emotional well-being, pain and general health perception. Results: A total of 35 patients, with a mean age of 60 years, completed the SF-36. The results showed difficulties across the physical and psychological domains, particularly affecting the return to previous roles and activities. A higher burden of co-morbidities as well as a more severe muscle weakness was associated to a lower physical functioning. Younger age, rather than older, correlated to a perceived greater limitation in physical functioning and vitality. Conclusions: COVID-19 survivors particularly the ones of working age may need support for resuming their premorbid level of functioning and returning to work.

scholarly journals ACNE;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Naima Luqman ◽  
Summaira Hassan ◽  
Niaz Maqsood ◽  
Wajid Ali Akhunzada
Keyword(s):  
Quality Of Life ◽  
Dermatology Life Quality Index ◽  
Outcome Measure ◽  
Life Quality ◽  
Descriptive Study ◽  
Large Impact ◽  
Age Group ◽  
Medical College ◽  
The Impact

Objectives: To determine the impact of acne on the quality of life of the patients. Study Design: A descriptive study. Place & Duration of Study: The study was conducted in the Department of Dermatology, Bahawal Victoria Hospital & Quaid-e-Azam Medical College, Bahawalpur April, 2017 to June, 2017. Subjects & Methods: The sample consisted of 50 out-patients (41 Females, 9 Males) with Acne. They were interviewed and results were analysed from the entries in a Performa. Dermatology Life Quality Index (DLQI) was administered as outcome measure. Results: Among 50 patients, there were 41(82%) were female, 27(54%) were 21-25 years age group, 44(88%) belonged to urban area, 28(56%) single and 25(50%) students. In assessing the quality of life, 34(68%) patients had extremely large impact on their quality of life after Acne. Conclusions: We concluded that acne had an extremely large impact on quality of life of majority of patients. Management of acne must include the impact of acne on the patient's quality of life.

scholarly journals The Impact of Reactogenicity After the First Dose of Recombinant Zoster Vaccine on the Physical Functioning and Quality of Life of Older Adults: An Open-Label, Phase III Trial

2018 ◽  
Vol 74 (8) ◽  
pp. 1217-1224 ◽  
Author(s):  
Kenneth E Schmader ◽  
Myron J Levin ◽  
Katrijn Grupping ◽  
Sean Matthews ◽  
David Butuk ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Functioning ◽  
Zoster Vaccine ◽  
Open Label ◽  
Post Dose ◽  
Systemic Reactions ◽  
Sf 36 ◽  
The Impact ◽  
Physical Functioning Score

Abstract Background Herpes zoster and its related complications are associated with significant medical burden, which negatively affects quality of life and daily functioning of the patients. The recently licensed recombinant zoster vaccine (RZV) offers high efficacy but is associated with local and systemic reactions. This study assessed the impact of RZV on the quality of life and daily functioning of participants and implications for caregivers. Methods Four hundred and one adults aged 50 years or older received single RZV doses at 0 and 2 months in this open-label, single-arm, multicenter study (NCT02979639). Change in mean SF-36 Physical Functioning score following first-dose administration, quality of life, reactogenicity, safety, productivity loss, and health care resource utilization was assessed. The current analysis was performed post-vaccine dose-1; safety follow-up will continue until 1 year post-dose-2. Results The most common solicited local symptoms were injection-site pain (77.5%), redness (23.0%), and swelling (13.3%); the most frequent solicited systemic reactions were fatigue (33.5%), headache (28.3%), and myalgia (26.8%). Grade 3 reactogenicity occurred in 9.5% of participants and was associated with a transient clinically important decrease in SF-36 Physical Functioning score (affecting activities such as walking, carrying groceries, climbing stairs) on Days 1 and 2 post-first vaccination. No clinically meaningful reductions in mean SF-36 Physical Functioning scale scores from pre- to post-RZV dose-1 were observed (mean +1.9 points, primary end point), and no overall quality-adjusted-life-year loss was recorded post-dose-1. Five participants reported lost workdays; caregiver workload was not increased. Conclusions Overall, the physical functioning and quality of life of older adults were not affected by a first RZV dose. The observed reactogenicity was consistent with previous studies.

scholarly journals Histopathological Pattern of Endometrial Biopsies in Patients with Abnormal Uterine Bleeding Attending Birat Medical College Teaching Hospital

2020 ◽  
Vol 5 (2) ◽  
pp. 1035-1039
Author(s):  
Neeta Kafle ◽  
Shilpi Shaukin ◽  
Santosh Upadhaya Kafle ◽  
Mrinalini Singh ◽  
Surya Bahadur Parajuli
Keyword(s):  
Teaching Hospital ◽  
Histopathological Examination ◽  
Age Groups ◽  
College Teaching ◽  
Abnormal Uterine Bleeding ◽  
Endometrial Biopsy ◽  
Uterine Bleeding ◽  
Age Group ◽  
Histological Pattern ◽  
Medical College

Introduction: Abnormal uterine bleeding (AUB) is one of the commonest gynaecological problems. Etiology of AUB may be structural and functional and varies according to age group. Histological pattern of endometrial sampling along with clinical and radiological findings remains the diagnostic standard for clinical diagnosis of endometrial pathology which ultimately helps in deciding the management of the patients. Objectives: To determine histopathological pattern of endometrial biopsies in patients with AUB attending Birat Medical College Teaching Hospital. To determine the pattern of menstrual abnormality in patients with AUB in different age groups. Methodology: We conducted a prospective hospital based cross sectional study for a period of one year (1 April 2019 to March 31 2020). Histopathological findings of all endometrial biopsy samples in patients with AUB were examined. Patients were categorized into different age groups and the patterns of menstrual abnormality were also documented. Results: 166 patients presenting with AUB underwent endometrial biopsy. Most of them were of perimenopausal age group (42.77%). Menorrhagia was the most common presenting menstrual abnormality. Histopathological examination predominantly revealed normal cyclical endometrium. Hyperplasia was seen more frequently in patients > 40 years of age. Malignancy was diagnosed in 2.41%, all were adenocarcinoma and was seen in > 50 years age. Conclusion: AUB is a common gynaeco-pathological problem with varied clinical presentation and multiple causes. Functional endometrial changes account for the highest histological pattern. However hyperplasia and malignancy are important cause of AUB in perimenopausal and post menopausal age group's women.

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