scholarly journals Impact of herbal drugs and its clinical application

2019 ◽  
Vol 10 (2) ◽  
pp. 1340-1345
Author(s):  
Vetriselvan Subramaniyan ◽  
Saminathan Kayarohanam ◽  
Ashok Kumar J ◽  
Vinoth Kumarasamy
Keyword(s):  
Health Care Professionals ◽  
Herbal Medicines ◽  
Drug Formulation ◽  
Therapeutic Effects ◽  
Clinical Use ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Alternative Medicines ◽  
Ancient Times ◽  
The Impact

Since ancient times until now exploring the importance of herbal medicines to treat the variety of diseases. Currently the herbal medicines searching for health, wellness and aim to achieve effective treatment without much side effect. Recent days the impact of herbal medicines well established even herbal treatment is one of the alternative medicines for most of the diseases such as hyperlipidemia, diabetes mellitus etc. Medicinal plants always have been rich sources of bioactive compounds, and that will be very helpful to human health. The reasons for herbal medicines attracted by the health care professionals and common individuals, including concern about confidence and safety of drugs. Allopathic medicines have many side effects and sometimes failing to treat and most of the herbal drugs proven better therapeutic effects without any major adverse effects. With the demand for phytomedicine user, this review highlights modern herbal drug formulation and its clinical use.

Herbal Drug Interactions

2017 ◽  
pp. 201-231 ◽  
Author(s):  
Mymoona Akhter
Keyword(s):  
Drug Interaction ◽  
Side Effects ◽  
Adverse Effects ◽  
Drug Interactions ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Herbal Therapy ◽  
Alternative Medicines ◽  
Regulatory Bodies

Use of complementary and alternative medicines (CAM) for preventive and therapeutic purposes has increased tremendously in the last two decades internationally. The manufacturers of these products are not required to submit proof of safety or efficacy to the Food and Drug Administration. As a result, the adverse effects and drug interactions associated with them are largely unknown. In this chapter, the author presents interactions of herbal medicines with other medicines (herbal or non-herbal). A large number of herbal drugs, including from single drug to a variety of mixtures have been used to treat kidney disorders. Herb-herb or herb drug interaction has been reported intensively during last decade, therefore it becomes important to keep an eye on the use of combination herbal therapy in order to avoid serious results because of interactions with each other. Due to the growing awareness about the interactions and side effects of herbal drugs/supplements over the past few years, regulatory bodies are working on these issues and pharmacopoeias are being developed for reference.

Herbal Drug Interactions

2022 ◽  
pp. 120-141
Author(s):  
Mymoona Akhter
Keyword(s):  
Drug Interaction ◽  
Side Effects ◽  
Adverse Effects ◽  
Drug Interactions ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Herbal Therapy ◽  
Alternative Medicines ◽  
Regulatory Bodies

Use of complementary and alternative medicines (CAM) for preventive and therapeutic purposes has increased tremendously in the last two decades internationally. The manufacturers of these products are not required to submit proof of safety or efficacy to the Food and Drug Administration. As a result, the adverse effects and drug interactions associated with them are largely unknown. In this chapter, the author presents interactions of herbal medicines with other medicines (herbal or non-herbal). A large number of herbal drugs, including from single drug to a variety of mixtures have been used to treat kidney disorders. Herb-herb or herb drug interaction has been reported intensively during last decade, therefore it becomes important to keep an eye on the use of combination herbal therapy in order to avoid serious results because of interactions with each other. Due to the growing awareness about the interactions and side effects of herbal drugs/supplements over the past few years, regulatory bodies are working on these issues and pharmacopoeias are being developed for reference.

Nano Phytomedicine Based Delivery System for CNS Disease

2020 ◽  
Vol 21 (9) ◽  
pp. 661-673 ◽  
Author(s):  
Mohammed Asadullah Jahangir ◽  
Chettupalli Anand ◽  
Abdul Muheem ◽  
Sadaf Jamal Gilani ◽  
Mohamad Taleuzzaman ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Low Cost ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Widespread Acceptance ◽  
The Central Nervous System ◽  
Low Toxicity ◽  
Ancient Times ◽  
Plant Sources ◽  
Herbal Formulations

Herbal medicines are being used since ancient times and are an important part of the alternative and traditional medicinal system. In recent decades, scientists are embracing herbal medicines based on the fact that a number of drugs that are currently in use are derived directly or indirectly from plant sources. Moreover, herbal drugs have lesser side effects, albeit are potentially strong therapeutic agents. The herbal medicine market is estimated to be around US $62 billion globally. Herbal medicine has gained widespread acceptance due to its low toxicity, low cost, ease of accessibility and efficacy in treating difficult diseases. Safety and efficacy are another important factors in the commercialization process of herbal medicines. Nanotechnology has been shown to be potentially effective in improving the bioactivity and bioavailability of herbal medicines. Development of nano-phytomedicines (or by reducing the size of phytomedicine), attaching polymers with phytomedicines and modifying the surface properties of herbal drugs, have increased the solubility, permeability and eventually the bioavailability of herbal formulations. Novel formulations such as niosomes, liposomes, nanospheres, phytosomes etc., can be exploited in this area. This article reviews herbal medicines, which have prominent activity in the Central Nervous System (CNS) disorders and reported nano-phytomedicines based delivery systems.

scholarly journals HERBAL DRUG-INDUCED ADVERSE DRUG REACTION: A CASE REPORT

2018 ◽  
Vol 11 (2) ◽  
pp. 9 ◽  
Author(s):  
Manju Gari ◽  
Lakhan Majhee ◽  
Kavita Kumari
Keyword(s):  
Adverse Effect ◽  
Adverse Drug Reaction ◽  
Health Care Professionals ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Drug Reactions ◽  
Drug Induced ◽  
Menstrual Disturbance ◽  
The World ◽  
Made In

  The present study done to focus many adverse drug reactions unrecorded with either patients failing to present to health services due to herbal medicine or no pharmacovigilance analysis is being made. In this case, a 55-year-old female patient with 41 kg weight, she received herbal treatment for gastritis and menstrual disturbance since November 2015. After administration of drug, she suddenly developed 23 small vesicles over neck and upper chest. Few vesicles ruptured over 4–5 days and few gradually increased in size to form bulla. The use of herbal drug has increased tremendously across the world in recent times. Hence, it has become important for pharmacovigilance of herbal drugs and adverse effect issues for the consumers and health-care professionals as it is complex to analyze these products than the conventional pharmaceuticals. “Safe” and “natural” cannot be used anonymously. Sufficient adverse drug monitoring of herbal drugs is as important as any other formularies.

scholarly journals A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

2016 ◽  
Vol 2016 ◽  
pp. 1-31 ◽  
Author(s):  
Piyush Mehta ◽  
Vividha Dhapte
Keyword(s):  
Chemical Constituents ◽  
Herbal Medicines ◽  
Pharmacokinetic Profile ◽  
Pharmacokinetic Data ◽  
Therapeutic Effects ◽  
Traditional Chinese Medicines ◽  
Herbal Drug ◽  
Major Drawback ◽  
Chinese Medicines ◽  
Wide Range

Herbal medicines are the oldest and most widely used form of treatment for welfare of mankind. Herbal medicines possess strong reputation as complementary treatment across the globe due to their easy accessibility and safety. Particularly traditional Chinese medicines (TCM) are very popular due to their desirable therapeutic effects. They already have been proven for their remarkable potential in treatment of wide range of disease ailments. The major drawback in using herbal medicines is lack of standardisation aspects due to the complexity of chemical constituents. Pharmacokinetics study of such medicines helps forecast a range of events related to efficacy, safety, and toxicity profile of them. Apart from this, pharmacokinetics studies also recommended by various regulatory agencies during diverse stages of herbal drug development. Thus it is highly essential to have knowledge about the pharmacokinetic properties of any herbal drug. Thus it was thought that it will be worthwhile to compile the pharmacokinetic data of TCM which will be helpful for the researchers involved in further research on TCM. To portray entire picture about absorption, distribution, metabolism, and excretion (ADME) of some TCM, this well-designed scientific review covers the pharmacokinetic profile of 50 TCM available from 2003 and onwards.

scholarly journals A Pharmacognostic review of Liquorice: Pharmacological actions, Current uses and Future prospects

2021 ◽  
pp. 38-45
Author(s):  
Veer Jashvantbhai Patel ◽  
Manish Mahebub Khetani
Keyword(s):  
Chemical Compounds ◽  
Pharmacological Effects ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Future Prospects ◽  
Active Chemical ◽  
Ancient Times ◽  
Current Article ◽  
Treatment Alternatives ◽  
Active Chemical Compound

Herbs used as medicines are one of the widely adopted treatment alternatives which is in effect since ancient times. Herbal drugs are of great importance to the population because of its ease of availability and the relief of having no side effects. Majority of the herbal drugs are possessed to have more than one pharmacological effect. One such classic example of well-known herbal drug is Liquorice which is commonly known as Sweet Wood or Mulethi. Liquorice is available in dried root or rhizome form and it is widely used as natural sweetener, expectorant and as a hepato-protectant. The herb is widely grown in Baluchistan, Spain and in certain parts of Himalayan region of India. There are various active chemical compounds of Liquorice which include saponins and flavonoids. The pharmacological actions of this drug are attributed to its major active chemical compound named Glycyrrhizin. Liquorice is also found to have specific anti-viral activity against certain viral cells. The current article focusses on the pharmacognostic review of Liquorice and its uses. The multiple pharmacological effects of this drug and the future prospects of using Liquorice in developing formulations have been discussed in detail.

scholarly journals A Comprehensive Review and Perspective of Herbal Medicines in the Treatment of COVID-19

2021 ◽  
pp. 70-95
Author(s):  
Afrasim Moin ◽  
S. Meenakshi ◽  
Syed Mohd Danish Rizvi ◽  
Nanhi Nandini ◽  
Talib Hussain ◽  
...  
Keyword(s):  
Drug Targets ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Efficacy And Safety ◽  
Direct Inhibition ◽  
Wuhan City ◽  
Herbal Products ◽  
Alternative Medicines ◽  
Global Concern ◽  
Approved Drugs

Background: An emergent COVID-19 outbreak originated in Wuhan City, in December 2019. The COVID-19 contamination has swiftly unfold from Wuhan to maximum different provinces and different 24 countries. WHO declared a public health emergency of global concern over this worldwide COVID-19 outbreak on 30th January 2020. Manifold research has been intensely initiated for immunization and drug development for COVID-19 till date no specific vaccine or approved drugs are accessible for COVID-19. Alternatively, therapy consists of supportive care and non-specific anti-viral, anti-malarial, and antibiotics are being testedas drugs for COVID-19. Though, novel approaches could play a crucial role to combat mortality rate and patient recovery in the treatment of COVID-19. Objective: To reveal the epidemiology, pathophysiology, and comparison of promising synthetic and natural drug targets to avert and cure of COVID-19. Method: This article sets a brief understanding of the viral characteristics, its life cycle, infection to humans, and the pathophysiology of the disease. It also throws light on the currently used synthetic medicines. we have reviewed the effect of natural products to prevent or treat COVID-19 infection. Their mechanisms of action have been elaborately discussed. literature research was undertaken using PubMed, Google Scholar, Scopus, and WHO website. The different herbal products (extracts) and their moieties which are promising as anti-SARS-CoV-2 by direct inhibition of the virus replication or entry has also been discussed. Results and Conclusion: In conclusion we have highlighted that natural therapeutics either alone or in combinationcould be used as alternative medicines to treat/prevent COVID-19 infection. Moreover, their structures may offer clues for the development of anti-SARS-CoV-2 drugs.The integration of nanocarriers for effectively delivering the conventional as well as the herbal drugs becomes a key point for their efficacy and safety.

Herbal medicines

2012 ◽  
Author(s):  
Philip Wiffen ◽  
Marc Mitchell ◽  
Melanie Snelling ◽  
Nicola Stoner
Keyword(s):  
Genetic Factors ◽  
Herbal Medicines ◽  
General Information ◽  
Complex Mixtures ◽  
Therapeutic Effects ◽  
Herbal Drugs ◽  
Efficacy And Safety ◽  
Active Constituents ◽  
Chinese Herbal ◽  
Herbal Medications

Herbal drugs 150General information about commonly used herbal medications 154Chinese herbal medicine 157Herbal interactions 158Perioperative considerations for herbal drugs 160The efficacy and safety of herbal drugs present a number of issues to pharmacists. Herbal drugs are more often complex mixtures of active constituents that vary in quality for a number of reasons, such as environmental and genetic factors. Furthermore, the constituents responsible for the claimed therapeutic effects are frequently unknown or only partly explained....

scholarly journals Complementary and Alternative Medicines for the Treatment of Hepatitis C: Perspectives of Users and CAM Practitioners

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Salamat Ali ◽  
Shahan Ullah ◽  
Vibhu Paudyal ◽  
Mashhood Ali ◽  
Muhammad Khalid Tipu ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Side Effects ◽  
Health Care Professionals ◽  
Herbal Medicines ◽  
Disease Status ◽  
Cross Sectional ◽  
Complementary And Alternative Medicines ◽  
Alternative Medicines ◽  
Lycopodium Clavatum ◽  
Complementary And Alternative

Background. Despite substantial progress in the treatment of hepatitis C through the use of direct-acting antivirals which have been shown to cure the disease, complementary and alternative medicines (CAM) are popular among patients as a substitute or complement of allopathic medicines. This study aimed to explore the perspectives of patients and CAM practitioners on the use of CAM for the treatment of hepatitis C in Pakistan. Methods. A cross-sectional design was adopted. Participants (CAM practitioners and patients) were recruited from the capital and two provinces: Khyber Pakhtunkhwa and Punjab of Pakistan. A survey using paper-based questionnaires, each specific for patients and CAM practitioners, was conducted to gather information pertaining to demography, disease status, treatment history, and participants’ perspectives (about the disease, reasons to switch to CAM, and referring source). Results. A total of 417 respondents (n = 284 patients, n = 133 practitioners) were recruited. Of the total patients, 170 (59.9%) had started CAM during the previous three months. There were 168 (59.2%) of the total patients who had used allopathic treatments for hepatitis C prior to their use of CAM. The confidence in CAM (24.6%), high cost (19%), and unbearable side effects (52.1%) of allopathic medicines were the main reasons to switch to CAM treatment. Majority (49.3%) of the patients were referred to CAM on the recommendations of relatives or care givers (17.3%) whereas only 9.5% were referred by health care professionals. Out of 133 practitioners, 48 (36.1%) were practicing herbal medicines. From practitioners’ perspectives, club-moss (Lycopodium clavatum) was the best treatment option for hepatitis C. The majority, 73 (54.9%), of the patients had chosen to use CAM because of the side effects of allopathic medicines. Patients who had previous “good experience” with CAM were the most common referral source (56.4%) for CAM use in hepatitis C. Conclusions. Patients’ beliefs in CAM, side effects of allopathic therapy, high cost of allopathic medicines, and referrals from previous CAM users are key factors in the switching of hepatitis C patients to CAM.

scholarly journals PHARMACEUTICAL AND PHYSIO-CHEMICAL STUDY OF SHILADHATRI YOGA (KALPIT)

2021 ◽  
Vol 10 (6) ◽  
pp. 3759-3761
Author(s):  
, Gajender
Keyword(s):  
Natural Resources ◽  
Herbal Medicines ◽  
Chemical Study ◽  
Herbal Drugs ◽  
Plant Products ◽  
Universal Principles ◽  
Disease Condition ◽  
Treatment Of Diabetes ◽  
Ancient Times ◽  
Separate Discipline

Ayurveda is a time-tested science. It is based on universal principles of nature; in ancient times it is mainly flourished through the herbal drugs but later the drugs failed to conquer the difficult disease conditions. Hence humans started searching for alternate natural resources. In this search a separate discipline was emerged oriented towards use of metals, minerals, and animal and plant products, designated as Rasa Shastra. Later, it flourished and superseded the herbal medicines. In the classics they mention that one can make his own drug by using his knowledge for any disease condition. That’s why here new drug Shiladhatri yoga (Kalpit) is formed for use in the treatment of Diabetes.

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