scholarly journals Effect of KAP Intervention Model on Resilience and Cancer-related Fatigue in Patients with Colorectal Cancer Undergoing Chemotherapy

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Hui Zhang
Keyword(s):  
Colorectal Cancer ◽  
Randomized Trial ◽  
Cancer Chemotherapy ◽  
Prospective Randomized Trial ◽  
Control Group ◽  
Observation Group ◽  
Intervention Model ◽  
Cancer Related Fatigue ◽  
Resilience Scale ◽  
The Difference

Objective: To explore the effect of KAP intervention mode on resilience and cancer-related fatigue in patients with colorectal cancer undergoing chemotherapy. Methods: A prospective randomized trial was conducted. 55 patients with colorectal cancer who received routine nursing from February 2018 to February 2019 were included in the control group, and 55 patients who received routine nursing + KAP intervention from March 2019 to March 2020 were included in the observation group. The scores of Resilience Scale and cancer-related fatigue scale (CFS) before and 6 months after intervention were compared between the two groups. Results: After 6 months of intervention, the score of resilience of the two groups was higher than that before intervention, and that of the observation group was higher than that of the control group, the difference was statistically significant (P < 0.05); The CFS score of the two groups was lower than that before intervention, and that of the observation group was lower than that of the control group, the difference was statistically significant (P < 0.05). Conclusion: KAP intervention model can improve the resilience of patients with colorectal cancer chemotherapy, reduce cancer-related fatigue.

Effect of Poria polysaccharide oral liquid on cancer-related fatigue in postoperative patients with colorectal cancer

2021 ◽  
Vol 7 (6) ◽  
pp. 6519-6528
Author(s):  
Wei Tan ◽  
Weidong Zhou ◽  
Youya Zhao ◽  
Tingting Fu ◽  
Xuhui Huang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Tumor Resection ◽  
Serum Levels ◽  
Control Group ◽  
Observation Group ◽  
Cancer Related Fatigue ◽  
Tnf Α ◽  
Oral Liquid

Objective: We aimed to explore the effect of Poria polysaccharide oral liquid (PPOL) on cancer-related fatigue (CRF) in postoperative patients with colorectal cancer. Methods: Fifty patients with colorectal cancer who were diagnosed in our hospital from March 2015 to March 2019 were included in this retrospective study. They were all underwent tumor resection. They were randomly divided into control group (n = 25) and observation group (n = 25). Patients in the control group were treated according to the F0LF0X4 chemotherapy regimen, and those in the observation group were treated with F0LF0X4 chemotherapy plus PPOL (10 ml/time, 3 times/day) for 6 weeks. The quality of life index (QL-index) and brief fatigue scale (BFI) were used to investigate the quality of life and fatigue, respectively. The serum levels of inflammatory factors, IL-6 and TNF-a, were measured. Results: Compared with the control group, the QL-index score in the observation group was significantly better (P< 0.05). Moreover, the BFI in the observation group was significantly lower than that in the control group (P < 0.05). Furthermore, the serum levels of IL-6 and TNF-α in the observation group were notably decreased in comparison with the control group (P < 0.05). Conclusion: PPOL can effectively improve the fatigue state of postoperative patients with colorectal cancer by reducing the levels of IL-6 and TNF- α and improving the quality of life.

scholarly journals Influences of Psychological Intervention on Negative Emotion, Cancer-Related Fatigue and Level of Hope in Lung Cancer Chemotherapy Patients Based on the PERMA Framework

2021 ◽  
Author(s):  
Min Tu ◽  
Fan Wang ◽  
Sanying Shen ◽  
Hui Wang ◽  
Jing Feng
Keyword(s):  
Lung Cancer ◽  
Cancer Chemotherapy ◽  
Psychological Intervention ◽  
Negative Emotion ◽  
Control Group ◽  
Observation Group ◽  
Self Rating ◽  
Cancer Related Fatigue ◽  
Chemotherapy Patients ◽  
Positive Psychological Intervention

Background: Psychological status is a decisive factor for regulating the lung cancer chemotherapy patients’ levels of fatigue and hope. Using the PERMA (Positive Emotion, Engagement, Relationships, Meaning, and Accomplishment) framework. We aimed to explore the influences of the psychological intervention on the patients’ negative emotion, cancer-related fatigue, and level of hope. Method: A total of 100 lung cancer chemotherapy patients admitted in Wuhan No.4 Hospital, China, from Jan 2018 to Aug 2019 were enrolled as research objects divided into the control group and observation group. Positive psychological intervention using the PERMA framework was given to the observation group. The scores of Post-Traumatic Growth Inventory (PTGI), Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), Cancer Fatigue Scale (CFS), and Herth Hope Index (HHI) were evaluated and compared in the two groups. Results: After the intervention, PTGI score in the observation group is higher than that in the control group, whereas the SAS and SDS scores are lower in the observation group than in the control group, and the differences are statistically significant (P<0.05). Score of each CFS dimension and total CFS score in the observation group are all lower than those in the control group, with statistically significant differences (P<0.05). Score of each HHI dimension and total HHI score are higher than those in the control group, and the differences are statistically significant (P<0.05). Conclusion: Positive psychological intervention using the PERMA framework can improve the emotional and fatigue state of lung cancer chemotherapy patients and elevate their level of hope.

scholarly journals Optimized Algebraic Reconstruction Algorithm Based Hemodynamic Changes in Color Doppler Ultrasound in Monitoring the Patients with Colorectal Cancer Undergoing Peripherally Inserted Central Catheter and Catheterization Nursing

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Miao Yu ◽  
Junhui Li ◽  
Yue Li ◽  
Lejing Yu
Keyword(s):  
Colorectal Cancer ◽  
Color Doppler ◽  
Color Doppler Ultrasound ◽  
Control Group ◽  
Observation Group ◽  
Hemodynamic Changes ◽  
Nursing Satisfaction ◽  
The Difference ◽  
And Control ◽  
Algebraic Reconstruction

The purpose of this study was to analyze the hemodynamic changes and nursing care of patients with colorectal cancer who were peripherally placed into the central venous catheter (PICC) by color Doppler ultrasound based on an optimized algebraic reconstruction (ART) (OART) algorithm. In this study, 150 patients with colorectal cancer were selected and randomly divided into observation group and control group, with 75 cases in each group. Different nursing interventions were carried out. An optimized algebraic reconstruction (OART) algorithm was proposed, and the traditional ART algorithm and filtered back-projection (FBP) algorithm were introduced for comparison. They were applied in ultrasounds of 150 colorectal cancer patients undergoing PICC. The results showed that the Dice coefficient (Dice) and peak signal-to-noise ratio (PSNR) of the OART algorithm were greater than those of the ART and FBP algorithms, while the difference function (DF) and the running time were opposite ( P  < 0.05). The blood flow velocity (BFV) and blood flow (BF) of the arm vein 5 days after puncture were the least, which were less than those before puncture and 10 days and 30 days after puncture ( P  < 0.05). Thrombosis was most likely to be found 4–6 days after puncture (28 cases), followed by 10–15 days after puncture (22 cases), and one day after the puncture (19 cases). The BFV and BF of patients with thrombosis were lower than those of patients without thrombosis ( P  < 0.05). The total infection rate of PICC in the observation group was 10.7%, which was lower than that in the control group 32.0%, P  < 0.05. Nursing satisfaction of patients in observation group and control group was 95.99% and 75.99%, respectively, P  < 0.05, and the difference was statistically significant. In short, the ORAT algorithm proposed had better performance than the traditional algorithms in ultrasound image reconstruction; strengthening nursing intervention for chemotherapy patients with colorectal cancer undergoing PICC could effectively reduce the infection rate of PICC and improve the nursing satisfaction of patients.

Short-term outcomes from a prospective randomized trial comparing laparoscopic and open surgery for colorectal cancer

2009 ◽  
Vol 96 (12) ◽  
pp. 1458-1467 ◽  
Author(s):  
J. Neudecker ◽  
F. Klein ◽  
R. Bittner ◽  
T. Carus ◽  
A. Stroux ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Randomized Trial ◽  
Open Surgery ◽  
Prospective Randomized Trial ◽  
Short Term

scholarly journals Analysis of the Effect of Three - Row Nail in Gastric Cancer Operation

1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Wang Guang yong
Keyword(s):  
Gastric Cancer ◽  
Methylene Blue ◽  
Clinical Application ◽  
Skin Flap ◽  
Control Group ◽  
Observation Group ◽  
External Reinforcement ◽  
Methylene Blue Test ◽  
The Difference ◽  
Observational Group

To study on the clinical efficacy of the repairing of the toe defect of the tip of the toe artery with skin flap. 48 patients with tip of toe defects who were admitted to our department from May 2014 to December 2015 were randomly divided into two groups: control group and observation group, 24 cases in each group. The patients in the control group were treated with abdominal pedicle flap while the patients in the observation group were treated with the toe artery skin flap for repair. The clinical curative effect of the two groups was analyzed. The total effective rate of clinical treatment was 23 (95.83%) in the observation group was significantly higher than that in the control group, 19 (79.16%), and the elasticity and texture of the flap were good and no obvious adverse reaction occurred. The difference between the two groups was significant, p<0.05. The use of the toe artery skin flap for the treatment of the tip of toe defect has a significant clinical effect, and no serious adverse reactions occurred, highly safety.15To explore the clinical application of three-row stapler in the operation of gastric cancer, and to provide a reference for clinical application. 31 patients with gastric cancer from January 2015 to April 2017 were randomly divided into observational group and control group. The observational group (n = 16) received three rows of the stapler; the control group (n = 15) received two rows of the stapler. The general condition, complication and anastomotic condition of the two groups were recorded, and the occurrence of anastomotic leakage was tested by methylene blue test. There was no significant difference in the operation time between the two groups ( P> 0.05). The length of stay in the hospital for the observational group was (16.17 ± 5.25) d, which was significantly lower than that of the control group (22.35 ± 7.18) d, the difference was statistically significant (P < 0.05). The incidence of complications was 7.14%, which was significantly lower than that of the control group (26.67%, P < 0.05). The number of bleeding in the anastomosis of the observational group was (0.87 ± 0.61), and the number of the outermost anastomosis was 0.95 ± 0.49, which was significantly lower than that of the control group (P<0.01). In the observational group, only one case (6.28%) was positive in the methylene blue test, which was significantly lower than that in the control group (20%) (P < 0.05). Three-row stapler can be used to treat the traditional two-row nail stapler, and no external reinforcement is needed after anastomosis. At the same time, it can effectively control the anastomotic bleeding, outer ring nail exposure and anastomotic leakage complications occur and clinical hospital stays shorter, more efficient treatment, worthy of clinical application.

scholarly journals Study on the clinical efficacy and mechanism of octreotide combined with thrombin in patients with liver

1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Zhang Xiuqin
Keyword(s):  
Liver Cirrhosis ◽  
Liver Function ◽  
Clinical Efficacy ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Before And After ◽  
Octreotide Treatment ◽  
The Difference ◽  
Treatment Observation

Objective: To observe the clinical efficacy of octreotide and thrombin in the treatment of patients with liver cirrhosis, and to explore the mechanism of octreotide and thrombin. Methods: 53 patients with cirrhosis were randomly divided into control group and observation group from January 2014 to January 2016. The control group of 26 patients, given octreotide treatment. Observation group of 27 cases, given octreotide and thrombin combination therapy. Comparison of two groups of patients with clinical efficacy and changes in liver function before and after treatment. Results: The effective rate (88.89%) in the observation group was significantly higher than that in the control group (65.38%), the difference was statistically significant (p < 0.05). Before treatment, the difference of liver function between the two groups was not statistically significant (p > 0.05). After treatment, the liver function indexes of the two groups were improved, and the observation group was superior to the control group, the difference was statistically significant (p < 0.05).

scholarly journals Clinical Observation of Zhuang Medicine Crystal Sugar Ye’An Decoction in Treating Senile Skin Pruritus and Its Effects on Serum IgE

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Yun Zhang ◽  
Yuying Lan
Keyword(s):  
Adverse Reactions ◽  
Clinical Observation ◽  
Skin Lesions ◽  
Effective Rate ◽  
Inflammatory Factors ◽  
Control Group ◽  
Observation Group ◽  
Serum Ige ◽  
The Difference ◽  
Lesion Severity

Objective: To discuss the specific application of Zhuang Medicine Crystal Sugar Ye’An Decoction in senile skin pruritus and its effects on serum IgE detection level. Methods: 90 patients with senile skin pruritus admitted to our hospital from February 2019 to April 2020 were randomly grouped. The general treatment effect, itching, secondary skin lesion severity, serum IL-6, IgE level and adverse reactions between 45 patients treated with Chlorcyclizine Hydrochloride Tablets (The control group) and 45 patients treated with Crystal Sugar Ye’An Decoction were compared. Results: The total effective rate of the treatment in the observation group was 93.33%, much higher than that in the control group, 75.56%. The difference was verified and statistically significant (P<0.05). Before the treatment, the itching area, frequency, duration and severity of secondary skin lesions were at the same level (P>0.05). After the treatment, the above data were all reduced, and the reduction of the observation group was more significant than that of the control group, indicating the difference was statistically significant (P<0.05). Before the treatment, there was no difference in serum IL-6 and IgE test data between the two groups (P>0.05). After the treatment, the tendency all declined, and that of the observation group was more obvious, indicating the difference was statistically significant (P<0.05). During the experiment, no obvious adverse reactions were observed in both groups. Conclusion: In the treatment of patients with senile pruritus, the application of Zhuang Medicine Crystal Sugar Ye’An Decoction is not only safe and reliable, but can promote the improvement of patients’ symptoms, adjust the level of inflammatory factors, and enhance clinical efficacy.

scholarly journals A Comparative Study on the Efficacy between Minimally Invasive Caries Removal Technique involving Carisolv and Traditional Mechanical Caries Removal in Treating Dental Caries in Children

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Jiaying Song
Keyword(s):  
Dental Caries ◽  
Minimally Invasive ◽  
Recovery Time ◽  
Control Group ◽  
Observation Group ◽  
Research Subjects ◽  
Removal Method ◽  
Caries Removal ◽  
The Difference ◽  
Removal Technique

Objective: To explore the curative effect of Carisolv, a minimally invasive caries removal technique and traditional mechanical caries removal treatment on children's dental caries. Methods: A total of 97 children with dental caries who were treated in the Department of Stomatology in Affiliated Hospital of Chifeng University, Chifeng from September 2017 to May 2019 were selected and recruited as the research subjects. They were divided into two groups by random number table method. Forty-nine individuals were assigned in the control group while the remaining 48 individuals in the observation group. The control group was treated with traditional mechanical caries removal method, and the observation group was treated with minimally invasive caries removal technique, i.e. Carisolv. Both groups were followed up for six months. The degree of pain, recovery time of dental function and complications after six months of treatment were observed in the two groups of children. Results: During the treatment, compared with the control group, the children in the observation group experienced lower degree of pain and had shorter recovery time of dental function. After six months of treatment, the incidence of complications in the observation group was lower than that in the control group. The difference was statistically significant (P<0.05). Conclusion: Compared with traditional mechanical caries removal method, Carisolv, a minimally invasive caries removal technique could reduce the pain of children during the treatment process, shorten the time to restore dental function, reduce the occurrence of complications, and had a better therapeutic effect in treating children’s dental caries.

scholarly journals Effect of iRoot BP Plus Pulpotomy for Immediate Repair in Children with Young Permanent Teeth Crown Fracture

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Jiaying Song
Keyword(s):  
Success Rate ◽  
Clinical Effect ◽  
Permanent Teeth ◽  
Control Group ◽  
Observation Group ◽  
Control Groups ◽  
Before And After ◽  
Random Number Table ◽  
The Difference ◽  
And Control

Objective: To explore the clinical effect of iRoot BP Plus pulpotomy for immediate repair in children with young permanent teeth crown fracture. Methods: From September 2017 to October 2018, 80 children (80 affected teeth) with young permanent teeth crown fracture who treated in the hospital were selected as the research objects. Random number table method was used to divide them into observation and control groups with each group of forty patients (40 affected teeth). The children in the control group were treated with calcium hydroxide resin, while the observation group were treated with iRoot BP Plus for immediate repair. The surgical success rate was compared between the two groups, and the pulp vitality before and after treatment were compared. Results: At 3 months and 6 months after surgery, the success rate of children in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). The percentage of children with negative pulp activity in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Immediate repair with iRoot BP Plus pulpotomy in children with young permanent teeth crown fracture has significant clinical effect.

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