Effect of Poria polysaccharide oral liquid on cancer-related fatigue in postoperative patients with colorectal cancer

2021 ◽  
Vol 7 (6) ◽  
pp. 6519-6528
Author(s):  
Wei Tan ◽  
Weidong Zhou ◽  
Youya Zhao ◽  
Tingting Fu ◽  
Xuhui Huang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Tumor Resection ◽  
Serum Levels ◽  
Control Group ◽  
Observation Group ◽  
Cancer Related Fatigue ◽  
Tnf Α ◽  
Oral Liquid

Objective: We aimed to explore the effect of Poria polysaccharide oral liquid (PPOL) on cancer-related fatigue (CRF) in postoperative patients with colorectal cancer. Methods: Fifty patients with colorectal cancer who were diagnosed in our hospital from March 2015 to March 2019 were included in this retrospective study. They were all underwent tumor resection. They were randomly divided into control group (n = 25) and observation group (n = 25). Patients in the control group were treated according to the F0LF0X4 chemotherapy regimen, and those in the observation group were treated with F0LF0X4 chemotherapy plus PPOL (10 ml/time, 3 times/day) for 6 weeks. The quality of life index (QL-index) and brief fatigue scale (BFI) were used to investigate the quality of life and fatigue, respectively. The serum levels of inflammatory factors, IL-6 and TNF-a, were measured. Results: Compared with the control group, the QL-index score in the observation group was significantly better (P< 0.05). Moreover, the BFI in the observation group was significantly lower than that in the control group (P < 0.05). Furthermore, the serum levels of IL-6 and TNF-α in the observation group were notably decreased in comparison with the control group (P < 0.05). Conclusion: PPOL can effectively improve the fatigue state of postoperative patients with colorectal cancer by reducing the levels of IL-6 and TNF- α and improving the quality of life.

scholarly journals Combined anesthesia shows better curative effect and less perioperative neuroendocrine disorder than general anesthesia in early stage NSCLC patients

2019 ◽  
Vol 47 (10) ◽  
pp. 4743-4752
Author(s):  
Jingbo Pi ◽  
Yi Sun ◽  
Zhenghong Zhang ◽  
Chengfu Wan
Keyword(s):  
Adverse Events ◽  
General Anesthesia ◽  
Early Stage ◽  
Tumor Resection ◽  
Serum Levels ◽  
Control Group ◽  
Observation Group ◽  
Early Stage Nsclc ◽  
Tnf Α ◽  
Hs Crp

Objectives We aimed to compare the effects of general anesthesia with combined epidural and general anesthesia in patients with early-stage non-small cell lung carcinoma (NSCLC). Methods Patients scheduled to undergo tumor resection with adjuvant chemoradiotherapy were eligible. Patients in the control group received general anesthesia during surgery, and those in the observation group received combined epidural and general anesthesia. The hemodynamic factors mean arterial pressure (MAP), heart rate, end-tidal carbon dioxide, and oxygen saturation were measured. Serum levels of pro-inflammatory cytokines interleukin (IL)-1, IL-8, high-sensitivity C-reactive protein (hs-CRP), and tumor necrosis factor (TNF)-α as well as β-endorphin were measured by enzyme-linked immunosorbent assay. Serum malondialdehyde (MDA) was measured using the thiobarbituric acid method. Results The incidence of specific adverse events was reduced and overall and disease-free survival were improved in the observation group compared with the control group. MAP was generally lower in the observation group compared with the control group, as were the serum levels of IL-1, IL-8, hs-CRP, TNF-α, and MDA. Conclusions Compared with general anesthesia, combined epidural and general anesthesia may inhibit the occurrence of short-term adverse events and improve long-term outcomes by inhibiting inflammatory responses in patients with early-stage NSCLC after tumor resection.

scholarly journals The Effect of Respiratory Rehabilitation Training on the Life Quality of Pneumoconiosis Patients

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Lijun Chen ◽  
Wang Xu ◽  
Xiaoyong Ma ◽  
Genggeng Yu ◽  
Jianfeng Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Knowledge ◽  
Pulmonary Ventilation ◽  
Life Quality ◽  
Control Group ◽  
Observation Group ◽  
Rehabilitation Training ◽  
Pulmonary Ventilation Function ◽  
Respiratory Rehabilitation

Objective: To explore the effect of respiratory rehabilitation training on the quality of life of pneumoconiosis patients. Methods: 76 pneumoconiosis patients who were treated in our hospital from April 2017 to December 2019 were selected as the research object, and randomly divided into 2 groups according to the order of admission by coin tossing, 38 cases in each group. The control group carried out health knowledge education on the basis of conventional treatment, and the observation group combined with respiratory rehabilitation training on the basis of the control group to compare the quality of life and lung function of the two groups of patients. Results: After 2 months of nursing care, scores of GQOLI-74 scale and pulmonary ventilation function indexes in the observation group were higher than those in the control group, with statistically significant differences (P<0.05). Conclusion: Respiratory rehabilitation training can improve pulmonary ventilation function of pneumoconiosis patients, improve the quality of life of patients, has good clinical application value.

scholarly journals Effect of KAP Intervention Model on Resilience and Cancer-related Fatigue in Patients with Colorectal Cancer Undergoing Chemotherapy

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Hui Zhang
Keyword(s):  
Colorectal Cancer ◽  
Randomized Trial ◽  
Cancer Chemotherapy ◽  
Prospective Randomized Trial ◽  
Control Group ◽  
Observation Group ◽  
Intervention Model ◽  
Cancer Related Fatigue ◽  
Resilience Scale ◽  
The Difference

Objective: To explore the effect of KAP intervention mode on resilience and cancer-related fatigue in patients with colorectal cancer undergoing chemotherapy. Methods: A prospective randomized trial was conducted. 55 patients with colorectal cancer who received routine nursing from February 2018 to February 2019 were included in the control group, and 55 patients who received routine nursing + KAP intervention from March 2019 to March 2020 were included in the observation group. The scores of Resilience Scale and cancer-related fatigue scale (CFS) before and 6 months after intervention were compared between the two groups. Results: After 6 months of intervention, the score of resilience of the two groups was higher than that before intervention, and that of the observation group was higher than that of the control group, the difference was statistically significant (P < 0.05); The CFS score of the two groups was lower than that before intervention, and that of the observation group was lower than that of the control group, the difference was statistically significant (P < 0.05). Conclusion: KAP intervention model can improve the resilience of patients with colorectal cancer chemotherapy, reduce cancer-related fatigue.

scholarly journals Study on the Effect of Pain Nursing Intervention in ENT Wards

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Baoyi Huang ◽  
Fengmei Xu ◽  
Hongmei Kuang
Keyword(s):  
Quality Of Life ◽  
Severe Pain ◽  
Nursing Intervention ◽  
Control Group ◽  
Nursing Interventions ◽  
Observation Group ◽  
Clinical Value ◽  
Clinical Nursing ◽  
And Control

Objective: To explore the effectiveness of pain nursing interventions for patients in ENT. Methods: The 200 ENT patients admitted from March 2018 to March 2020 were divided into observation group (n=100) and control group (n=100). The control group was used conventional clinical nursing methods, and the observation group received pain nursing intervention as a comparison with the control group. Results: The observation group had 83 cases, 14 cases and 3 cases of mild, moderate and severe pain, respectively, while the control group are of 43 cases, 43cases and 14 cases. Nursing intervention can significantly reduce the pain of patients after otolaryngology surgery, improve the quality of life of patients, and has high clinical value for application.

scholarly journals Insulin Glargine and Acarbose in the treatment of elderly patients with diabetes

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Jing Li ◽  
Jinzhi Ji ◽  
Fuyan Liu ◽  
Lingling Wang
Keyword(s):  
Quality Of Life ◽  
Blood Glucose ◽  
Elderly Patients ◽  
Insulin Glargine ◽  
Adverse Reactions ◽  
Postprandial Blood Glucose ◽  
Control Group ◽  
Observation Group ◽  
Patients With Diabetes

Objective: To investigate the clinical efficacy of insulin glargine combined with acarbose in the treatment of elderly patients with diabetes. Methods: One hundred and forty-four elderly patients with diabetes who received treatment between December 2016 and December 2017 in Binzhou People’s Hospital, China, were selected and divided into a control group and an observation group, 72 each, using random number table. The control group was treated with insulin glargine, while the observation group was treated with insulin glargine combined with acarbose. The therapeutic effect, improvement of quality of life and adverse reactions were compared between the two groups. Results: After treatment, fasting blood glucose (FBG), 2h postprandial blood glucose (PBG) and glycosylated hemoglobin (Hb Alc) of the two groups were lower than those before treatment, and the decrease degree of the observation group was significantly larger than that of the control group (P<0.05). The time needed for blood glucose reaching the standard level and daily insulin dosage of the observation group were significantly lower than that of the control group, and the differences were statistically significant (P<0.05). SF-36 scale score of the observation group was significantly better than the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combination of insulin Glargine and Acarbose can significantly control the blood glucose level of elderly patients with diabetes, improve the biochemical indicators, and enhance the quality of life. It is worth promotion in clinical practice. doi: https://doi.org/10.12669/pjms.35.3.86 How to cite this:Li J, Ji J, Liu F, Wang L. Insulin Glargine and Acarbose in the treatment of elderly patients with diabetes. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.86 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Analysis of the Application Effect of Health Education in Skin Care

2021 ◽  
Vol 9 (4) ◽  
pp. 75
Author(s):  
Weijie Qi
Keyword(s):  
Quality Of Life ◽  
Health Education ◽  
Skin Diseases ◽  
Treatment Time ◽  
Control Group ◽  
Observation Group ◽  
Hamd Score ◽  
Mood Score ◽  
The Difference

<p>Objective: to analyze the effect of health education intervention in clinical nursing of patients with skin diseases. Methods: from January 2018 to March 2019, 122 patients with skin diseases were admitted to our hospital and randomly divided into two groups, with 61 cases in each group. The selected patients gave informed consent to this study. The control group was given routine dermatological care, and the observation group was given systematic health education. The treatment effect, mood score and quality of life score of the two groups were compared. Results: the treatment time, recurrence times and outpatient treatment times of the observation group were lower than those of the control group, the difference was statistically significant (P &lt; 0.05); the HAMA score and HAMD score of the observation group after intervention were lower than the control group, the difference was statistically significant (P &lt; 0.05). Conclusion: the implementation of health education for patients with skin diseases during the nursing process can effectively promote the recovery of the condition and reduce the number of treatments and recurrences. At the same time, it can improve the patients’ bad mental mood and improve the quality of life of the patients.</p>

Application Effect Analysis of Nursing Intervention in Stem Cell Therapy for Stroke Patients

2021 ◽  
Vol 7 (4) ◽  
pp. 392-399
Author(s):  
Jing Zhao ◽  
Lili Fu ◽  
Juan Zhu ◽  
Yan Liu ◽  
Xiaoqian Sun
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Daily Living ◽  
Nursing Intervention ◽  
Control Group ◽  
Observation Group ◽  
Stroke Patients

To study and analyze the actual clinical effect of nursing intervention in stem cell therapy for stroke patients. A total of 9 stroke patients treated with stem cell therapy in our hospital from September 2018 to September 2019 were selected as the research and analysis objects. All patients were divided into observation group 5 stroke patients and control group 4 stroke patients by random number method. Both groups of patients were treated with stem cell therapy. Patients in the control group were treated with conventional nursing methods, and patients in the observation group were treated with nursing intervention methods. The treatment compliance, psychological status, quality of life and daily living ability before and after intervention were compared between the two groups. There were no significant differences in exercise training, disease monitoring and compliance with regular life between the two groups before intervention (P > 0.05), and the patients in observation group were significantly better than those in control group after intervention (P < 0.05), with significant differences. There was no significant difference in anxiety and depression scores between the two groups before intervention (P > 0.05), and after intervention, the patients in the observation group were significantly lower than those in the control group (P < 0.05), and the difference was statistically significant. There was no significant difference in quality of life and ability of daily living between the two groups before intervention (P > 0.05), and the patients in the observation group were significantly better than those in the control group after intervention (P < 0.05), the difference was statistically significant. The application of nursing intervention in stem cell therapy for stroke patients has a significant effect, which significantly improves the patient's compliance with the treatment, alleviates the negative emotions of patients, improves the psychological status of patients, improves the quality of life and daily living ability of patients, and is worthy of popularization and application in clinical nursing.

scholarly journals Application of quality control circle in the treatment of moderate cancer pain in inpatients

2020 ◽  
Vol 50 (5) ◽  
pp. 581-585
Author(s):  
Yehuan Liu ◽  
Beibei Lin
Keyword(s):  
Quality Of Life ◽  
Quality Control ◽  
Cancer Pain ◽  
Pain Control ◽  
Management Tool ◽  
Control Group ◽  
Observation Group ◽  
Patients With Cancer ◽  
Significant Difference

Abstract Context Pain is one of the most common and intolerable symptoms in cancer patients. But cancer pain control is still negative in China. Objectives This paper explores the application of quality control circle in the treatment of cancer pain in inpatients to improve the quality of life of patients with cancer pain. Method Established a quality control circle group to analyze the current status of cancer pain control in inpatients with moderate cancer pain, set goals, formulate corresponding countermeasures and implement and review them in stages. The plan-do-check-act method was cyclically applied. The Brief Pain Inventory was used to evaluate the cancer pain status of patients with cancer pain hospitalized before (January to April 2016) and after (September to December 2016) the implementation of quality control circle activities. Results The pain control effect of the observation group was significantly better than that of the control group. The mean (standard deviation) of pain severity and pain interference in the observation group were significantly lower than those in the control group (6.21 [2.86] vs 4.31 [2.25], 10.54 [4.10] vs 7.25 [3.77]). There was significant difference after the implementation of quality control circle (P &lt; 0.01). Conclusion Quality control circle activities are used to manage patients with cancer pain, to improve the situation of pain control and to improve the quality of life of patients. This management tool and method is worthy of clinical promotion and application.

scholarly journals Effect of Whole-course Nutrition Management on Patients with Esophageal Cancer Undergoing Concurrent Chemoradiotherapy: A Randomized Control Trial (P05-031-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Yanfang Qiu ◽  
Jie You ◽  
Quanjun Lv ◽  
Ling Yuan
Keyword(s):  
Quality Of Life ◽  
Esophageal Cancer ◽  
Nutritional Status ◽  
Concurrent Chemoradiotherapy ◽  
Nutrition Support ◽  
Control Group ◽  
Observation Group ◽  
Skin Reactions ◽  
Nutrition Management

Abstract Objectives Malnutrition is the most common complication of patients with esophageal cancer, and can lead to poor prognosis and death. It has been shown that good nutritional status can help improve patient outcomes and reduce complications. In the absence of specific evidence of the effect of nutrition on patients with esophageal cancer, the purpose of this study was to investigate the effect of total nutrition management on the prognosis and complications of patients with esophageal cancer through a randomized controlled trial. Methods 96 patients with esophageal cancer concurrent chemoradiation were randomized to observation group (treated by whole-nutrition management from the Nutrition Support Group (NST)) and control group (treated by the general nutritional method) for 6 weeks approximately. Dietary survey, Patient-Generated Subjective Global Assessment (PG-SGA), body measurement, blood index, quality of life survey and psychological condition survey were assessed at baseline and every week/at the end of the study. Complications, the completion rates of therapy, short-term efficacy evaluation as well as clinical outcomes were measured before discharge. Results A total of 85 subjects completed the study (observation group = 45, control group = 40). There were significantly different in the changes in serum albumin, prealbumin, and total protein between two groups throughout the trial (P < 0.05). Radioactive esophagitis, skin symptom of the complications, the roles, emotional functions, social functions, and general health status in the quality of life were statistically different before and after the intervention (P < 0.05). The difference in the change of other indicators was not statistically significant. Conclusions Whole-course nutrition management can improve the nutritional status of patients with concurrent chemoradiotherapy of esophageal cancer, reduce the severity of radiation esophagitis and radiation skin reactions, improve the quality of life and relieve their depressive symptoms. Funding Sources Wu Jieping Medical Foundation Special Fund for Clinical Research of 2017.

scholarly journals Retrospective Analysis of the Clinical Efficacy of Early Goal-Directed Therapy Combined with Meticulous Nursing Intervention in Patients with Posttraumatic Sepsis

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Zhe Yuan ◽  
Shilu Yang ◽  
Chunhua Zhang ◽  
Ke Chen ◽  
Minhuan Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Survival Rate ◽  
Venous Pressure ◽  
Nursing Intervention ◽  
Control Group ◽  
Observation Group ◽  
Central Venous ◽  
Goal Directed Therapy ◽  
Early Goal Directed Therapy

Objective. To explore the intervention effect of early goal-directed therapy (EGDT) combined with meticulous nursing on patients with posttraumatic sepsis. Methods. The data of 50 patients with posttraumatic sepsis undergoing EGDT in the emergency department of our hospital from January 2020 to December 2020 were retrospectively analyzed. According to different nursing methods, they were divided into control group (n = 25) with routine nursing measures and observation group (n = 25) with meticulous nursing measures. The application effect of the two nursing modes was scientifically evaluated. Results. No statistical differences in general data were found between the two groups ( P > 0.05 ). After 6 h of intervention, the circulatory function, oxygenation function, and renal function of both groups were better than those before intervention, and central venous pressure (CVP), mean arterial pressure (MAP), blood oxygen (PaO2), oxygenation index (PaO2/FiO2), central venous oxygen saturation (ScvO2), and urine volume in the observation group were notably higher than those in the control group ( P < 0.05 ). The heart rate (HR), serum creatinine (SCr), and blood lactic acid in the observation group were notably lower than those in the control group ( P < 0.05 ). The 28-day survival rate and quality of life after intervention in the observation group were notably higher than those in the control group, with obvious differences between the two groups ( P < 0.05 ). Conclusion. Meticulous nursing intervention for patients with posttraumatic sepsis undergoing EGDT can effectively improve the body’s functional indexes, which is superior to the routine nursing in controlling the patients’ condition, improving the survival rate and quality of life after intervention, and ensuring the clinical treatment effect. Therefore, it is worthy of promotion.

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