scholarly journals Application Value of Lung-Fire-Clearing, Phlegm-Resolving, and Bowels-Relaxing Decoction in Treating Lung Cancer of Phlegm-Heat Pattern

2021 ◽  
Vol 5 (4) ◽  
pp. 103-107
Author(s):  
Limei Qin
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Reference Group ◽  
Control Group ◽  
Cytokeratin 19 ◽  
Study Group ◽  
Clinical Effects ◽  
Carbohydrate Antigen 125 ◽  
Heat Pattern

Objective: This article explores the clinical effects of lung-fire-clearing, phlegm-resolving and bowels-relaxing decoction in the treatment of lung cancer of phlegm-heat pattern. Methods: A total of 6 cases of lung cancer patients with phlegm-heat pattern were randomly selected from Inner Mongolia Baicaotang Qin’s Zhong Meng Medical Hospital from March 2018 to December 2020 to conduct the study. They were divided into the reference group and the study group by using the digital table method. The patients in the reference group were treated with conventional Western medicine whereas the patients in the study group were treated with lung-fire-clearing, phlegm-resolving, and bowels-relaxing decoction to observe the curative effect. Results: There were no significant differences in the levels of the tumor markers between the two groups before treatment (P > 0.05). However, after treatment, the levels of cytokeratin 19 soluble fragments (CYFRA21-1), carbohydrate antigen 125 (CA125), and carcinoembryonic antigen (CEA) in the study group were lower than those in the control group (P < 0.05). The effective rate and the quality of life score of the study group were higher than those of the reference group while the incidence of adverse reactions was lower than that of the reference group, P < 0.05. Conclusion: Lung-fire-clearing, phlegm-resolving, and bowels-relaxing decoction can effectively improve the symptoms of patients with lung cancer and improve their quality of life.

scholarly journals Evaluation of quality of life in patients with locally advanced non-small cell lung cancer treated with combined radiochemotherapy

2003 ◽  
Vol 11 (3) ◽  
pp. 196-196
Author(s):  
Suzana Isakovic-Vidovic ◽  
Nenad Borojevic ◽  
Ljiljana Radosevic-Jelic ◽  
Tatjana Pekmezovic
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Locally Advanced ◽  
Small Cell ◽  
Control Group ◽  
Study Group ◽  
Small Cell Lung ◽  
Combined Radiochemotherapy

Background: The aim was to investigate the application of radiopotentiation which was initiated by the fact that in patients with locally advanced non-small cell lung cancer there is a high risk of relapse due to failure in local control of the disease and the risk of systemic micrometastases. The other aim was the evaluation of quality of life. Methods: A study group consisted of 67 patients. Patients were first treated with TD30 Gy in 10 fractions during 2 weeks (5 fractions per week) with a potentiation by 20 mg/m 2 of carboplatinol intravenous bolus infusion just prior to each radiotherapy fraction. After a 2-week pause, additional radiation of 25 Gy in 10 fractions was applied during 2 weeks (5 fractions/week) with a potentiation by 20 mg/m 2 of carboplatinol. Total tumor dose (TTD) was 55 Gy (30+25 Gy) in 20 fractions, total duration of the therapy was 6 weeks, and total dose of carboplatinol was 600 mg. A control group consisted of 70 patients and they were treated with a radical radiotherapy with a conventional fractionation (60 Gy in 30 fractions, 2 Gy per day, 5 fractions per week). Quality of life was evaluated by Karnofsky performance scale (KI), at the beginning of the treatment, after the completion of the whole course of treatment, and during follow-up at regular check-ups. Results After the completion of the whole course of treatment most of patients had KI 80%. Analysis made during the last check-up showed statistically significant low KI. In both study and control groups KI was significantly higher at the beginning of the treatment than KI after the completion of the whole course of treatment (p=0.001). However, the analysis of KI at the time of the completion of the whole course of treatment showed significantly better KI in study group (p=0.036) than in control group. Conclusion: These results showed that the combined radiochemotherapy treatment is well tolerated.

scholarly journals Clinical Effect of Lung Qi-Diffusing and Tumor-Clearing Decoction in the Treatment of Advanced Lung Cancer

2021 ◽  
Vol 5 (6) ◽  
pp. 38-42
Author(s):  
Limei Qin
Keyword(s):  
Lung Cancer ◽  
Adverse Reactions ◽  
Clinical Effect ◽  
Reference Group ◽  
Advanced Lung Cancer ◽  
Control Group ◽  
Therapeutic Effects ◽  
Study Group ◽  
Conventional Chemotherapy

Objective: The main purpose of this study is to explore the efficacy of lung qi-diffusing and tumor-clearing decoction in the treatment of advanced lung cancer. Methods: Eight patients with advanced lung cancer in Inner Mongolia Baicaotang Qin’s Zhong Meng Medical Hospital from February 2017 to October 2020 were randomly selected and divided into two groups, a control group and a study group, by the digital table method. The control group was treated with conventional chemotherapy, while the study group was treated with lung qi-diffusing and tumor-clearing decoction on this basis. The therapeutic effects of the two groups were observed. Results: The improvement in symptoms of the patients in the study group was higher than that of the reference group, and the incidence of adverse reactions was lower among patients in the study group compared to the reference group, P < 0.05. The serum immunological indexes, CD3+, CD4+, and CD4+/CD8+, of study group were higher than those of the reference group, and the quality-of-life score of the study group was higher than that of the reference group, P < 0.05. Conclusion: The clinical effect of lung qi-diffusing and tumor-clearing decoction in the treatment of patients with advanced lung cancer is significant. It effectively improves the immune indicators and reduces adverse reactions.

scholarly journals Effects of Docetaxel Combined with Icotinib on Serum Tumor Markers and Quality of Life of Patients with Advanced Non-Small Cell Lung Cancer

2020 ◽  
Author(s):  
Huawei LIN ◽  
Jing CHANG ◽  
Jun LI
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Tumor Markers ◽  
Adverse Reactions ◽  
Advanced Nsclc ◽  
Small Cell ◽  
Control Group ◽  
Study Group ◽  
Small Cell Lung

Background: To investigate the effects of docetaxel combined with icotinib on tumor markers in serum and quality of life of patients with advanced non-small cell lung cancer (NSCLC). Methods: Overall, 121 patients with advanced NSCLC, admitted to the Third Affiliated Hospital of Shandong First Medical University, China from 2017- 2018 were selected as subjects. Among them, 58 patients treated with docetaxel combined with icotinib for chemotherapy were considered as study group, and 63 patients treated with paclitaxel combined with carboplatin as control group. The clinical efficacy, adverse reactions, and ECOG scores of the two groups were observed. CEA, CA125, and SCC (Tumor markers) levels of the two groups before and after treatment were detected by chemiluminescence immunoassay (CLIA). Results: The leukopenia, oral mucosa ulcer and mild numbness in the control group were significantly higher than those in the study group (P<0.05). After treatment, ECOG scores of both groups decreased (P<0.05), and the ECOG score of the study group was significantly higher than that of the control group (P<0.05). The serum CEA, CA125 and SCC levels of the study group and the control group after treatment decreased significantly compared with that before treatment (P<0.05). Conclusion: Application of docetaxel combined with icotinib for chemotherapy of patients with advanced NSCLC can effectively reduce the serum levels of CEA, SCC, and the CA125. Docetaxel combined with icotinib can significantly reduce adverse reactions and better improve the quality of life of patients compared with paclitaxel combined with carboplatin, which is worthy of clinical promotion.  

Analysis of the Impact of Personalized Nursing Service and Hospice Care on the Quality of Life of Elderly Cancer Patients

2021 ◽  
Vol 7 (4) ◽  
pp. 469-473
Author(s):  
Ting Fang ◽  
Nian Wang ◽  
Meng Chen ◽  
Hongmei Ma
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Hospice Care ◽  
Pain Treatment ◽  
Control Group ◽  
Study Group ◽  
The Difference ◽  
The Impact

Objective Explore the impact of personalized nursing services and hospice care on the quality of life of elderly patients with advanced cancer. Method We selected 80 elderly cancer patients admitted to our hospital from September 2020 to May 2021, and divided these patients into a study group and a control group using a random number table method. The patients in the control group used conventional nursing methods to treat and care for the patients, and the patients in the study group used hospice care measures and combined personalized nursing measures. The quality of life and pain treatment effects of the two groups of patients before and after treatment were compared. Result Before treatment, the quality-of-life scores of the two groups of patients were low, and there was no statistical difference (P>0.05); After treatment, the quality of life of the two groups of patients improved, but compared with the control group, the improvement was more obvious in the study group, and the difference was statistically significant (P<0.05). In terms of pain treatment effect, the total effective rate of pain treatment in the study group was 87.5%, which was significantly better than the 62.5% in the control group. The difference was statistically significant (P<0.05). Conclusion Personalized nursing services and hospice care are conducive to improving the survival and treatment of elderly patients with advanced cancer, and can be used as a clinical application program for the care of advanced cancer patients.

The effects of breathing exercises on respiratory functions, functional capacity and quality of life in vehicle spray painters

2021 ◽  
Vol 28 (12) ◽  
pp. 1-8
Author(s):  
Burak Yilmaz ◽  
Cagtay Maden ◽  
Begümhan Turhan
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Control Group ◽  
Study Group ◽  
Breathing Exercises ◽  
Sf 36 ◽  
Significant Difference ◽  
Before And After ◽  
Respiratory Exercises

Background/aims Workers engaged in vehicle spray painting are at a risk of developing respiratory problems because of the solvents in the spray paints. Changes in respiratory functions and functional capacities caused by spray painting can be improved with respiratory exercises. The aim of this study was to examine the effects of respiratory exercises on the respiratory functions, functional capacity and quality of life in vehicle spray painters. Methods A total of 70 volunteers with similar characteristics participated in the study. The groups were divided into two groups randomly (35 study group, 35 control group). Respiratory functions (value of forced expiratory volume percentage in 1 second [FEV1]), forced vital capacity percentage [FVC], FEV1/FVC percentage, peak expiratory flow percentage [PEF (%)] and maximum voluntary ventilation percentage [MVV (%)]), functional capacity (6-Minute Walk Test) and quality of life (Short Form Health Survey [SF-36]) were evaluated. The study group undertook supervised breathing exercises 3 days a week for 6 weeks. The same exercises were given to the control group as a home programme. Home programmes were followed up by telephone calls. Evaluations were performed again after 6 weeks. Results In the study group, FEV1 (%) increased more than in the control group (P<0.05). The increase in PEF (%) was similar in both groups (P>0.05). In the study group, FEV1/FVC (%) and MVV (%) were significantly different before and after the intervention (P<0.05), but there was no difference in the control group (P>0.05). There was a greater increase in the study group than in the control group (P<0.05). 6-Minute Walk Test distance (m) before and after the intervention in both groups were similar (P>0.05). Before and after the intervention, a significant difference was found in the vitality and the social function domains of the SF-36 in the study group. In the comparisons of groups, a significant difference was found in the study group in the role-emotional, social function and bodily pain domains of the SF-36 after the intervention (P<0.05). Conclusions Breathing exercises can be recommended for vehicle spray painters to avoid an increase in respiratory resistance and to improve their quality of life.

scholarly journals The Effects of Oral Nutritional Support on the Ability of the COVID-19 Patients to Recover: A Prospective, Open, Multicenter, Comparative in Two Groups, Observational Study

2021 ◽  
Vol 1 (4) ◽  
pp. 165-177
Author(s):  
Sergey V. Sviridov ◽  
Kirill Y. Krylov ◽  
Irina V. Vedenina ◽  
Rubenas Mohan
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Length Of Stay ◽  
Observational Study ◽  
Nutritional Support ◽  
Respiratory Support ◽  
Control Group ◽  
Study Group ◽  
Sf 36

Background. Nutritional insufficiency and decreased muscle mass of patients diagnosed with COVID-19 leads to prolonged respiratory support, stay in ICU and hospital, as well as reduced muscle strength and quality of life in the recovery period after a viral pneumonia caused by COVID-19. Aims: To study the effects of oral nutritional support on the physical health recovery of COVID-19 patients. Materials and methods. A prospective, open, multicenter, comparative observative study of two groups, observational study was initiated to evaluate the effects of oral nutritional support (ONS) by Nutridrink 200 ml on the ability of COVID-19 patients to recover. The patients with these criteria were included in the study: aged 1869; a confirmed COVID-19 infection; requires respiratory support; ability to consume more than 60% of food from the total required; presence of a signed consent form. One group received supplementary oral nutritional support (ONS) everyday for 28 days from the day of inclusion. The other group received standard diet. The primary endpoint was the evaluation of quality of life using the SF-36 questionnaire and the changes in the hand grip strength between the 3rd and 1st visits. Secondary endpoints of the study were length of stay in hospital and duration of respiratory support in the hospital. Results. 205 patients with a COVID-19 infection were included in the study. The final number of patients included in the study was 185 patients. Median age was 55 years old. The majority of patients were male 57.84% (107 patients). Upon evaluation of the physical component of quality of life using the SF-36 questionnaire, we obtained a statistically significant difference between the control and study groups on the 4th visit 44.285.45 and 46.586.76 respectively (p=0.012). Muscle strength was statistically different in the control (4.011.15 daN) and study (6.12.06 daN) groups (p 0.0001). The duration of respiratory support was significantly lower in the study group, 6.71.30 days as opposed to 8.141.52 days in the control group (p 0.0001). Also, in the group with oral nutritional support, there was a statistically significant decrease in the length of stay in hospital. In the control group, the average length of stay in hospital was 16.472.93 days, whereas in the study group it was 13.162.69 days (p 0.0001). Conclusion. Oral nutritional support given to oxygen dependent COVID-19 patients improves rehabilitation potential including preservation of muscle mass and function, reducing oxygen support requirements and length of stay in hospital.

scholarly journals Efficacy and safety of electro-acupuncture (EA) on insomnia in patients with lung cancer: study protocol of a randomized controlled trial

Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Hongyu Yue ◽  
Shuang Zhou ◽  
Huangan Wu ◽  
Xuan Yin ◽  
Shanshan Li ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Survivors ◽  
Controlled Trial ◽  
Control Group ◽  
Life Questionnaire ◽  
Efficacy And Safety ◽  
Symptom Scale ◽  
Significance Level

Abstract Background Cancer-related insomnia (CRI) is one of the most prevalent complaints among cancer survivors and severely impairs patients’ quality of life. As a popular non-pharmacological alternative treatment, acupuncture provides a good clinical curative effect on insomnia. The aim of this trial is to evaluate efficacy and safety of electro-acupuncture on insomnia in patients with lung cancer. Method This is a protocol for a multicenter randomized single-blinded sham-controlled trial. We will randomly assign 252 eligible patients with lung cancer-related insomnia into two groups at a ratio of 1:1, the treatment group (EA) and the control group (sham EA). All treatment will be given 3 times per week for 8 weeks, and a 12-week follow-up will be conducted. The primary outcome will be measured by the Pittsburgh Sleep Quality Index (PSQI). The secondary outcomes will include sleep parameters recorded from the actigraphy, scores from Quality of Life Questionnaire Core-30 (QLQ-C30), and Patient Health Questionnaire-9 (PHQ-9). All adverse effects during the trial will be assessed by the Treatment Emergent Symptom Scale (TESS). All analyses will be based on ITT principle and performed with the statistical software SPSS (version 24.0) by t test, rank-sum test, chi-square, and so on. A two-sided significance level will be set at 5%. Discussion This large-sample trial protocol will evaluate the efficacy of electro-acupuncture on insomnia in patients with lung cancer. This protocol, if proven to be effective, will contribute to filling the gap in treatment options in the CRI field and provide a promising intervention for insomnia in lung cancer survivors. Trial registration ChiCTR ChiCTR1900026395. Registered on 8 October 2019, http://www.chictr.org.cn/showproj.aspx?proj=44068

scholarly journals Efficacy of psychological intervention for patients with psoriasis vulgaris: a prospective study

2020 ◽  
Vol 48 (10) ◽  
pp. 030006052096167
Author(s):  
Xiaoli Li ◽  
Liangliang Liu ◽  
Yanfei Zhang ◽  
Li Li
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Psoriasis Vulgaris ◽  
Psychological Intervention ◽  
Compliance Rate ◽  
Psychological Status ◽  
Control Group ◽  
Study Group ◽  
Self Rating

Objective The study aim was to examine the effect of a psychological intervention on patients with psoriasis vulgaris. Methods Participants in this prospective study were 205 patients with psoriasis vulgaris, 104 who received a psychological intervention (study group) and 101 who received routine nursing care (control group). An additional 291 healthy subjects formed a non-psoriasis group. The Symptom Checklist-90 (SCL-90), Generic Quality of Life Inventory (GQOLI), Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) were used to evaluate psychological status and quality of life. Results There were significant differences in SCL-90 and GQOLI scores between the study and non-psoriasis groups. After treatment, the study group showed significantly improved scores on the SCL-90 and GQOLI compared with the control group. Scores on the SDS (mean ± standard deviation: 31.99 ± 4.54 vs. 44.08 ± 4.52) and SAS (28.36 ± 4.52 vs. 40.14 ± 6.33) were improved in the study group. In addition, patients in the study group showed higher satisfaction rate and compliance rate than those in the control group. Conclusion Psychological intervention may be beneficial for improving quality of life and the therapeutic efficacy of drugs in patients with psoriasis.

scholarly journals Impact of nursing interventions and patients education on quality of life regarding renal stones treated by percutaneous nephrolithotomy

2017 ◽  
Vol 7 (12) ◽  
pp. 52
Author(s):  
Rasha Ali Ahmed Abdelmowla ◽  
Attyiat Hassan Hussein ◽  
Ahmed Abdelhamaid Shahat ◽  
Hanan Ali Ahmed Abdelmowla ◽  
Medhat Ahmed Abdalla
Keyword(s):  
Quality Of Life ◽  
Percutaneous Nephrolithotomy ◽  
Short Form ◽  
Renal Stones ◽  
Favorable Effect ◽  
Control Group ◽  
Nursing Interventions ◽  
Study Group ◽  
And Control

Background and objective: Renal stones are a common and recurrent condition that requires medical or surgical treatment; all have significant impact on quality of life. The objective of this study was to detect factors affecting quality of life, improve quality of life for patients with renal stones treated by percutaneous nephrolithotomy.Methods: Research design: Prospective randomized controlled trail. Patients and methods: Random sample of 160 patients with renal stones planned for treatment by percutaneous nephrolithotomy at Assiut Urology and Nephrology Hospital were randomized into study and control groups. Study group (80 patients who received nursing interventions and patients education) and control group (80 patients who received routine hospital care). Their age ranged from18-65 years from both sexes. Tools: I Patient assessment sheet, II Rand short form 36 items questionnaire and III Teaching booklet.Results: Study group was showed a good improvement on quality of life after providing nursing interventions and patients education.Conclusions and recommendation: Nursing interventions and patients education for study group had a favorable effect on improving quality of life. Patients with percutaneous nephrolithotomy should receive careful care and education to improve their quality of life.

scholarly journals Transurethral Resection of Prostate for the Treatment of Advanced Prostate Cancer and Bladder Outlet Infarction

1970 ◽  
Vol 1 (2) ◽  
Author(s):  
Chenglin Huang
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Endocrine Therapy ◽  
Transurethral Resection ◽  
Advanced Prostate Cancer ◽  
Control Group ◽  
Transurethral Resection Of Prostate ◽  
Study Group ◽  
Better Than

Objective: To investigate the feasibility of transurethral resection of prostate and the treatment of advanced prostate cancer and bladder outlet infarction, and to analyze the therapeutic effect. Methods: 34 patients with advanced prostate cancer admitted in our hospital from April 2014 to April 2014 were divided into control group (17 cases) with routine endocrine therapy. The study group (17 cases) underwent urethral resection surgery Combined with endocrine therapy, through the relevant indicators of prostate treatment were observed to explore the two groups of patients with therapeutic effect. Results: According to the related indexes of prostate treatment, the treatment effect of the study group was significantly better than that of the control group, and the data of the two groups were statistically significant (P<0.05). Conclusion: The treatment of advanced prostate cancer patients with endocrine combined with transurethral resection of the prostate can effectively treat the symptoms of bladder outlet infarction and improve the quality of life of patients. It has certain value in clinical treatment.

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