scholarly journals Clinical Manifestations and Maternal and Infant Outcomes of Pregnancy Complicated with Thrombocytopenia

2021 ◽  
Vol 5 (6) ◽  
pp. 43-46
Author(s):  
Limin Hou ◽  
Qiuying Gao ◽  
Ben Niu ◽  
Yanchuan Li
Keyword(s):  
Pregnant Women ◽  
Research Group ◽  
Mode Of Delivery ◽  
Clinical Manifestations ◽  
Premature Delivery ◽  
Control Group ◽  
Infant Outcomes ◽  
Coagulation Function ◽  
Significant Difference ◽  
Maternal And Infant Outcomes

Objective: To explore the clinical manifestations as well as maternal and infant outcomes of pregnancy complicated with thrombocytopenia. Methods: A total of 478 pregnant women with thrombocytopenia, treated in Shaanxi Provincial People’s Hospital from July 2019 to June 2021, were selected as the research group, while 200 normal pregnant women, treated during the same period, were selected as the control group to analyze gestational thrombocytopenia (GT), idiopathic thrombocytopenic purpura (ITP), pregnancy-induced hypertension (PIH), adverse maternal and infant outcomes, etc. Results: Among the 478 patients in the research group, the main causes of pregnancy complicated with thrombocytopenia were GT, ITP, and PIH, accounting for 75.51%, 6.49%, and 8.79%, respectively, while other causes accounted for 9.21%. There was no significant difference between the research group and the control group in the amount of intrapartum bleeding, premature delivery, stillbirth, thrombocytopenia, and neonatal asphyxia, but there was significant difference in the mode of delivery (P < 0.05). Conclusion: The traditional indexes of coagulation function are not abnormal with decreased platelets in pregnant women with thrombocytopenia, but the indexes of thromboelasticity are abnormal and can reflect the changes of coagulation function. The cesarean section rate of patients with thrombocytopenia in pregnancy increases with the decrease of platelet count, but the mode of delivery should be determined in consideration of specific conditions.

scholarly journals Effect and Safety of Iron Supplementation on Mild Thalassemia Complicated by Iron Deficiency in Late Pregnancy

2021 ◽  
Vol 5 (6) ◽  
pp. 15-18
Author(s):  
Yanchuan Li ◽  
Yanfeng Liu ◽  
Xue Li ◽  
Limin Hou
Keyword(s):  
Iron Deficiency ◽  
Hemorrhagic Shock ◽  
Pregnant Women ◽  
Research Group ◽  
Iron Supplementation ◽  
Late Pregnancy ◽  
Premature Delivery ◽  
Control Group ◽  
Significant Difference ◽  
Intrapartum Hemorrhage

Aim: To study the clinical effect and safety of iron supplementation in the treatment of mild thalassemia complicated by iron deficiency in late pregnancy. Methods: 376 patients with mild thalassemia complicated by iron deficiency in late pregnancy treated in our hospital from July 2019 to June 2021 were selected and recruited in the research group, and 200 normal pregnant women treated in the same period were selected and recruited in the control group. Hemoglobin (Hb), reticulocyte blood, red blood protein (RET he) level, ferritin (SF) level, soluble transferrin receptor (sTfR) level, adverse maternal and infant outcomes, etc. were analyzed. Results: There was no significant difference in the levels of SF, Hb, RET he and sTfR between the two groups before treatment. After treatment, the levels of SF, Hb, RET he and sTfR in the research group were significantly improved, which was statistically significant compared with the control group. The frequencies of intrapartum hemorrhage, premature delivery, stillbirth, hemorrhagic shock, and neonatal asphyxia in the research group were 289±47.88, 36 (9.57%), 0 (0.00%), 25 (6.65%), and 6 (1.26%), respectively. The frequencies of intrapartum hemorrhage, premature delivery, stillbirth, hemorrhagic shock, and neonatal asphyxia in the control group were 284 ± 46.99, 7 (3.50%), 0 (0.00%), 6 (3.00%), and 0 (0.00%), respectively. There were significant differences in preterm delivery and hemorrhagic shock, and there was no significant difference in other delivery outcomes. Conclusions: Under the premise of strictly controlling the iron reserve in pregnant women, continuous medication until the end of delivery may be conducive to the control of maternal thalassemia complicated by iron deficiency and the improvement of pregnancy outcome.

Subclinical tuberculosis and adverse infant outcomes in pregnant women with HIV

2020 ◽  
Vol 24 (7) ◽  
pp. 681-685 ◽  
Author(s):  
H. M. Rickman ◽  
S. Cohn ◽  
S. G. Lala ◽  
Z. Waja ◽  
N. Salazar-Austin ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Adverse Outcomes ◽  
Hiv Positive ◽  
Control Group ◽  
Infant Outcomes ◽  
Smear Negative ◽  
Women With Hiv ◽  
Negative Controls ◽  
The Impact ◽  
Maternal And Infant Outcomes

BACKGROUND: Tuberculosis (TB) in pregnant women with HIV is associated with adverse maternal and infant outcomes. Previous studies have described a substantial prevalence of subclinical TB in this group, but little is known about the impact of subclinical TB on maternal and pediatric outcomes.METHODS: The Tshepiso Study recruited 235 HIV-infected pregnant women with TB (and matched HIV-positive, TB-negative pregnant controls), in Soweto, South Africa, from 2011 to 2014. During enrolment screening, some women initially recruited as controls were subsequently diagnosed with prevalent TB. We therefore assessed the prevalence of subclinical TB, associated participant characteristics and outcomes.RESULTS: Of 162 women initially recruited as TB-negative controls, seven (4.3%) were found to have TB on sputum culture. All seven had negative WHO symptom screens, and six (86%) were smear-negative. Of their seven infants, one was diagnosed with TB, and three (43%) experienced complications compared to zero infants with TB and 11% experiencing complications in the control group of TB-negative mothers (P = 0.045).CONCLUSION: We discovered an appreciable prevalence of subclinical TB in HIV-infected pregnant women in Soweto, which had not been detected by screening algorithms based solely on symptoms. Infants of HIV-infected mothers with subclinical TB appear to have a higher risk of adverse outcomes than those of TB-negative mothers.

scholarly journals Comparison of the Mode of Delivery between COVID and Non-COVID Pregnancies

2021 ◽  
Vol 11 (9) ◽  
pp. 277-283
Author(s):  
Saima Najam ◽  
Shehla Aqeel ◽  
Syeda Ifra Hassan
Keyword(s):  
Caesarean Section ◽  
Pregnant Women ◽  
Null Hypothesis ◽  
Mode Of Delivery ◽  
Active Phase ◽  
Current Evidence ◽  
Control Group ◽  
Significant Difference ◽  
Third Stage ◽  
Study Population

Background: The pregnant women and the newborn infants represent the vulnerable population in every society. Therefore Improvement efforts for the survival and the well being of the mothers and the neonates is indisputably a global priority especially during this pandemic of severe acute respiratory syndrome caused by a novel corona virus, called Covid-19. declared by the WHO ( World Health Association ) as global pandemic on March 11,2020. This pandemic has significantly altered the life styles of the pregnant women, boosting their apprehensions and concerns and importing great impacts on their health management. Current evidence suggests that the pregnant women are not at increased risk of Covid -19 as compared to the other adults. Similarly the condition is not severe in them. At the place of the current study the mode of delivery of the Covid patients is individualized and based on severity of the Covid infection and purely on the obstetric indications, as the evidence suggests that no mode of delivery is superior in terms of prevention of the vertical transmission. Objective: We performed this study to compare the mode of delivery between the pregnant Covid and the non Covid pregnant population with the null hypothesis that the Covid effected pregnant patients are more prone to have caesarean section as compared to non Covid pregnant females and they are more prone to have CTG (cardiotocographic) abnormalities. Material and Methods: It was a retrospective observational study done to compare the mode of delivery and the rate of CTG abnormalities in the study and the control group as the primary outcome. The secondary outcome was duration of active phase of the first stage, second and third stage of the labour between the pregnant Covid and the non Covid pregnant population for a period of 6 months (First January 2021 -30th June 2021) in labor ward of Dr. Sulaiman Al-Habib Hospital, Sweidi, Riyadh, Saudi Arabia. The study population comprised of 100 pregnant patients meeting our inclusion and exclusion criteria. The number of patients in each group was equal. Results: No statistically significant difference was observed in the age, parity and ethnicity of both the groups. The rate of caesarean section was 38% (n=19) in the Covid group while in the control group it was 10% (n=05), the difference is statistically significant as shown by the P-Value of 0.004. No significant difference in the CTG abnormalities was found in both the groups. However statistically significant reduction in the active phase of the first, second and third stage of labour was noted in the study population. Conclusion: We hereby prove our null hypothesis that the Covid-19 effected pregnant patients are prone to have higher caesarean section rate, however no difference in rate of CTG (cardiotocographic) abnormalities was observed in both the groups. Significant reduction in the duration of all stages of the labour was also noticed which is a fruit of thought for the upcoming research. Key words: Pregnancy, labour, caesarean section, Covid-19, duration of labour.

Optimisation of tactics of conducting pregnancy and labours at women after auxiliary reproductive technologies

2016 ◽  
pp. 160-164
Author(s):  
D.N. Maslo ◽  
Keyword(s):  
Pregnant Women ◽  
Resistance Index ◽  
First Trimester ◽  
Reproductive Technologies ◽  
Premature Delivery ◽  
Control Group ◽  
Uterine Arteries ◽  
Placental Dysfunction ◽  
Placental Blood ◽  
Two Stages

The objective: frequency decrease perinatal pathologies at women after ART on the basis of studying clinical-ehografical, endocrinological, biochemical, dopplerometrical, cardiotokografical and morphological researches, and also improvement of algorithm of diagnostic and treatment-and-prophylactic actions. Patients and methods. The work basis is made spent by us from 2012 on 2015 by complex inspection of 300 pregnant women from which 250 were after ART and 50 – firstlabours which pragnency without ART, and also their newborns. For the decision of an object in view of research spent to two stages. At 1 stage spent prosperctive research which included 150 pregnant women: з them 100 women pregnancy at which has come out ART (1 group) and 50 healthy women (control group). At 2 stage spent prospective randomization in which result of patients after ART have divided on two equal groups by therapy principle: 2 basic group - 75 pregnant women after ART at which used the algorithm improved by us; 3 group of comparison - 75 pregnant women after ART which have been spent on the standard treatment-and-prophylactic actions. Results. The results suggest that women after using ART is a high frequency of reproductive losses in the first trimester (10.0%), 3.0% of spontaneous abortion from 16 to 22 weeks, and 3.0% "early" premature delivery (22 to 28 weeks of pregnancy). The frequency of violations of the functional state of placenta in women after using IVF is 63.0%, which is the main cause of high levels of perinatal losses (40.0 ‰), and delivery by cesarean section (96.0%). Placental dysfunction in women after using ART characterized by retrohorialnyh hematoma (21.0%); size mismatch fruit (30.0%) and hypertonicity of the uterus (73.0%) against changes in fruit-placental blood flow - increased resistance index in umbilical artery and increased vascular resistance in the uterine arteries. Endocrinological and biochemical changes in placental dysfunction in women after using IVF starting from 28 weeks of pregnancy and are in significant reduction in progesterone, placental b1-microglobulin, B2-microglobulin of fertility and trophic в-glycoprotein. Conclusion. The received results: use of the algorithm of diagnostic and treatment-and-prophylactic actions improved by us allows to lower frequency of spontaneous interruption of pregnancy till 22 weeks – from 13.0% to 5.7%; «early» premature birth – from 3.0% to 1.0%; placentary dysfunction from 63.0% to 40.6%; cesarean sections – from 96.0% to 56.5%, and also perinatal losses – from 40.0‰ to 16.2‰. Key words: pregnancy, childbirth, auxiliary reproductive technologies.

Breastfeeding Training through Role-Play and Effects on Mother-infant Attachment Behaviours: A Randomised Controlled Trial

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Farokh Saljughi ◽  
Mitra Savabi-Esfahani ◽  
Shahnaz Kohan ◽  
Soheila Ehsanpour
Keyword(s):  
Pregnant Women ◽  
Maternal Employment ◽  
Controlled Trial ◽  
Role Play ◽  
Intervention Group ◽  
Control Group ◽  
Maternal Behaviour ◽  
Infant Attachment ◽  
Significant Difference ◽  
History Of

Mother-infant attachment is an intimate, lasting and satisfying relationship that leads to better cognitive, emotional and social growth of the infant. The aim of this study was to determine the effects of breastfeeding training by role-play on mother-infant attachment behaviours. This research was a randomised clinical trial (parallel design). Inclusion criteria were: no history of mental disorders; ability to read and write the Persian language to complete the questionnaire; no history of drug and tobacco intake in primigravida women. The sample comprised 100 pregnant women (in 2 groups), selected through simple random sampling at healthcare centres. The researcher reviewed prenatal care registries of selected healthcare centres and extracted the names of pregnant women in their early third trimester. The data were imported into randomisation software. The control group received routine breastfeeding training, while the intervention group received routine training together with training through role-play. The data collection tool was the Maternal Behaviour Inventory Questionnaire. Consequently 75 samples were analysed in SPSS16. Independent t-tests and chi-square tests were used to examine the difference between the two groups. Results showed that the mean score of mother-infant attachment one week after delivery was significantly higher in the intervention group in comparison to that in the control group (p<0.001). No significant difference was observed between the two groups in maternal age, age of marriage, neonatal gender, maternal employment and education, number of parity, and number of abortions (P>0.05). Since breastfeeding training through role-play could affect mother-infant attachment, it is suggested that this type of training should be provided for pregnant women to promote mother-infant attachment and exclusive breastfeeding.

Thyroid Dysfunction in Pregnant Women with Gestational Diabetes Mellitus

2020 ◽  
Vol 16 (8) ◽  
pp. 895-899 ◽  
Author(s):  
Shahin Safian ◽  
Farzaneh Esna-Ashari ◽  
Shiva Borzouei
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Control Group ◽  
Thyroid Peroxidase ◽  
Free T4 ◽  
Significant Difference ◽  
Experimental Group

Aims: Investigation thyroid dysfunction and autoimmunity in pregnant women with gestational diabetes mellitus. Background: This article was written to evaluate the thyroid function and anti-thyroid peroxidase (anti- TPO) antibodies in pregnant women with gestational diabetes mellitus (GDM). Method: A total of 252 women with GDM and 252 healthy pregnant women were enrolled. Thyroid tests, including TSH, FreeT3, Free T4, and anti-TPO were performed for all women at 24–28 weeks of gestation. Data analysis was then carried out using SPSS ver. 22. Result: There was a significant difference between the experimental group (38.4%) and the control group (14.06%) in terms of the prevalence of subclinical hypothyroidism (p= 0.016). The frequency of anti-TPO was higher in the experimental group than the control group and positive anti-TPO was observed in 18.6% of women with GDM and 10.3% of healthy pregnant women (P= 0.008). Conclusion: Thyroid disorders are observed in pregnant women with GDM more frequently than healthy individuals and it may be thus reasonable to perform thyroid tests routinely.

Effect of Focusing on Maryam’s Flower During the First Stage of the Labor on the Labor Pain, Labor Duration, and Levels of Comfort and Satisfaction

2020 ◽  
pp. 105477382098491
Author(s):  
Hülya Türkmen ◽  
Serap Çetinkaya ◽  
Hafize Kiliç ◽  
Emine Apay ◽  
Devrim Karamüftüoğlu ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Intervention Group ◽  
Comfort Level ◽  
Labor Pain ◽  
Cervical Dilatation ◽  
Control Group ◽  
Flower Opening ◽  
Labor Duration ◽  
Significant Difference ◽  
Physical Comfort

This randomized controlled experimental study was conducted with an intervention group ( n = 61) and a control group ( n = 63) consisting of primipara pregnant women. The pregnant women in the intervention group were asked to focus their attention on Maryam’s flower opening its leaf buds and imagine the labor’s progress during the course of their labor. The VAS was administered to each group at specific times (at 4–5 cm, 6–7 cm, 8–9 cm cervical dilatation) to determine their level of labor pain. A statistically significant difference was found between the groups’ mean pain scores at 4–5 cm, 6–7 cm, and 8–9 cm cervical dilatation ( p < .05). The labor duration of the pregnant women in the intervention group was significantly shorter than that of the pregnant women in the control group ( p = .017). The physical comfort level of the intervention group was significantly higher than that of the control group at 8–9 cm cervical dilatation ( p = .039).

scholarly journals The effect of nutrition and reproductive health education of pregnant women in Indonesia using quasi experimental study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tria Astika Endah Permatasari ◽  
Fauza Rizqiya ◽  
Walliyana Kusumaningati ◽  
Inne Indraaryani Suryaalamsah ◽  
Zahrofa Hermiwahyoeni
Keyword(s):  
Health Education ◽  
Reproductive Health ◽  
Pregnant Women ◽  
Intervention Group ◽  
Control Group ◽  
Attitudes And Practices ◽  
Significant Difference ◽  
Reproductive Health Education ◽  
Post Test ◽  
Knowledge Attitudes And Practices

Abstract Background Almost one-third of children under 5 years old in Indonesia suffer from stunting. Stunting can be prevented optimally during pregnancy as the initial phase of the first 1000 days of life. This study aims to determine the effect of nutrition and reproductive health education of pregnant women in Bogor Regency, Indonesia. Methods A quasi-experimental study was conducted among 194 pregnant women from August to November 2019. The pregnant women were randomly selected from four different villages in Bogor Regency. The intervention group (n = 97) received 2 h of nutrition and reproductive health education in small groups (four or five mothers per group) every 2 weeks for 3 consecutive months. This interactive education was given by facilitators using techniques such as lectures, role-playing, simulation, and games. The control group (n = 97) received regular health care services. A structured questionnaire was applied to collect data consisting of maternal characteristics, nutritional and reproductive health knowledge, attitudes, and practices in the intervention and control groups. Data were analysed using t-test and chi-square analysis. Results Pregnant women in the intervention group indicated a significant increase in knowledge, attitudes, and practices regarding nutrition and reproductive health after receiving education. The pre-test and post-test mean scores in the intervention group were 55.1 and 83.1 for overall knowledge, 40.2 and 49.0 for attitudes, and 36.2 and 40.2 for practices, respectively. In the control group, there was no significant difference between the pre-test and post-test mean scores for these three variables. There was a significant difference (P < 0.001) in the post-test mean between the intervention group and the control group, but the difference was not significant (P > 0.05) in the pre-test. Conclusion Providing nutrition and reproductive health education through small groups with interactive methods improves the knowledge, attitudes, and practices of pregnant women. This intervention has the potential to be replicated and developed for large-scale implementation by optimising collaboration between government, non-governmental organizations, and maternal and child health service providers.

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