scholarly journals Efficiency of Application of Pilates as a Mean of Physical Therapy in Women with Degenerative-Dystrophic Lesions of the Lumbar Spine

2021 ◽  
Vol 6 (5) ◽  
pp. 450-455
Author(s):  
T. Odynets ◽  
◽  
O. Kolomiichenko ◽  
Keyword(s):  
Lumbar Spine ◽  
Physical Therapy ◽  
Functional State ◽  
Comparison Group ◽  
Effective Means ◽  
Spinal Pain ◽  
Main Group ◽  
Middle Aged ◽  
Permanent Disability ◽  
Body Retention

Degenerative-dystrophic lesions of the lumbar spine are characterized by a systemic multifactorial course and significantly affect the quality of life. Spinal pain due to degenerative-dystrophic diseases very often affects middle-aged people, in particular women, leading to temporary or permanent disability. Degenerative-dystrophic diseases of the spine are accompanied by neurological manifestations, pain syndromes, prone to a protracted course and have repeated relapses. The purpose of the study was to determine the features of physical therapy to improve the functional state of the spine in middle-aged women with degenerative-dystrophic lesions of the lumbar spine. Materials and methods. The following research methods were used in the study: theoretical analysis of scientific and methodological literature, empirical (determination of the functional state of the muscles of the trunk), pedagogical experiment, methods of mathematical statistics. The study involved 28 women. The main group and the comparison group of 14 people each were formed by the method of random sampling, the average age of the subjects was 40.44 ± 1.25 and 41.60 ± 1.14 years old, respectively. The main group was studied according to the developed program of physical therapy with the use of Pilates, the comparison group – according to the program of therapeutic gymnastics (general developmental orientation) of the communal non-profit enterprise "Zaporizhzhya Regional Clinical Hospital". The study of the functional state of the muscles of the trunk was assessed according to the following tests: the time of holding the lateral support; keeping the support lying on the forearms; static body retention; holding the torso at an angle of 60˚; flexion and extension of the spine. Results and discussion. According to the results of the final rehabilitation examination, it was found that in the comparison group it was not possible to record a possible improvement in the functional state of the muscles of the trunk and the amplitude of the spine. At the same time in the main group such changes occurred in all the studied parameters. In particular, the index of lateral support retention in the main group significantly increased by 8.00 s (p <0.05), retention of the support lying on the forearms – by 10.00 s (p <0.05), static trunk retention - by 9.5 s (p <0.05), holding the trunk at an angle of 60˚ - by 10.00 s (p <0.05), flexion of the spine – by 3.00 cm (p <0.05), extension of the spine – by 5.00 cm (p <0.05). Conclusion. The results of the study indicate that Pilates is an effective means of improving the functional state of the muscles of the trunk and the amplitude of the spine, which was confirmed by significantly better indicators of functional tests in the main group compared with the women in the comparison group

scholarly journals Application of pilates means in physical therapy of middle age women with degenerative-dystrophic lesions of the lumbar department

2021 ◽  
pp. 91-94
Author(s):  
T.Ye. Odynets ◽  
O.Yu. Kolomyichenko
Keyword(s):  
Physical Therapy ◽  
Comparison Group ◽  
Middle Age ◽  
Sedentary Lifestyle ◽  
Early Stage ◽  
Main Group ◽  
Middle Aged ◽  
Analog Scale ◽  
Vital Functions ◽  
Reasonable Choice

Degenerative-dystrophic diseases in middle-aged women are a common pathology of the spine, which is caused by a sedentary lifestyle, insufficient attention to the problem of spinal health and signs of the disease at an early stage of its development. Purpose: to determine the features of improving the vital functions of middle-aged women with degenerative-dystrophic lesions of the lumbar spine by Pilates. Research methods: theoretical analysis of scientific and methodological literature, empirical (questionnaires by Ostwestry, Rolland-Morris, visual-analog scale), pedagogical experiment, methods of mathematical statistics. The women of the main group were engaged in the developed program of physical therapy, which provides a reasonable choice of tools and methods, taking into account age, pain and functional status of the spine. For each patient of the main group, the means and methods of physical rehabilitation were selected individually, which would most effectively help to solve the problem and achieve the set goal. Classes were held individually 4 times a week for 40-50 minutes. Results: experimental verification of the effectiveness of the developed program of physical therapy showed that at the end of the study women of the main group had better indicators according to the questionnaire Osvestri by 9.86 points (p<0.05), Roland-Morris - by 2.41 points (p<0.05), the indicator of VAS - by 1 point (p<0.05) compared with women in the comparison group, respectively, which confirmed the effectiveness of the proposed program of physical therapy with the means of Pilates.

scholarly journals THE EXPERTISE OF THE CAUSAL RELATIONSHIP BETWEEN THE DEVELOPMENT OF ARTERIAL HYPERTENSION WITH PARTICIPATION IN WORKS FOR LIQUIDATION OF THE CONSEQUENCES OF CHORNOBYL NPP ACCIDENT IN REMOTE POSTACCIDENTAL PERIOD

2020 ◽  
Vol 25 ◽  
pp. 543-557
Author(s):  
V. Sushko ◽  
◽  
O. Tatarenko ◽  
O. Kolosynska ◽  
D. Hapieienko ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Radiation Exposure ◽  
Causal Relationship ◽  
Inpatient Treatment ◽  
Comparison Group ◽  
Main Group ◽  
Vascular Events ◽  
Permanent Disability ◽  
Medical Expertise ◽  
Relationship Of

Loss of health and work ability, as well as deaths from diseases of the circulatory system (DCS), first of all arterial hypertension (AH), due to radiation exposure (RE) in the conditions of Chernobyl catastrophe (ChC) in the performance of professional, military or official duties and / or living on radiation-contaminated areas, additional exposure not through their own fault but due to a radiation accident, caused the development of a special form of medical expertise as part of the of medical social protection system for these suffered contingents. Objective: to optimize decision-making criteria for the expert estimation of the casual relationship between development and progression of AH under the influence of RE in clean-up workers of the Chornobyl NPP accident (CWs) in the remote postaccidental period based on the study of odds ratio (OR) of the course of the disease. Material and methods. A retrospective analysis of the structure of 16073 cases of victims of the Chornobyl NPP (ChNPP) accident, considered by the Central Interagency Expert Commission of Ministry of Health of Ukraine for diseases, reason of disability and death causal relationship to ChNPP accident (CIEC) during 2014–2016, allowed to form a group of 401 cases of CW with AH to determine the OR of the course of the disease. The main group consisted of 330 CWs for whom the development of AH has a causal relationship with the participation in the work for liquidation consequences of the Chornobyl NPP accident (WLAc), the comparison group – 71 CWs in respect of whom a negative expert decision was made. There were not significant differences between both groups of CWs in dose of external radiation exposure (DERE) in the main group – (0.155 ± 0.085) Sv, in CWs of the comparison group – (0.135 ± 0.086) Sv (р = 0.868). Results. In the remote postaccidental period, HSC take the second place (39.62 %) in the structure of medical expertise of the causal relationship of the diseases development and progression with RE for all categories of victims of the Chernobyl accident. The share of cases of AH was 28.4% of the total number of cases considered CWs. In the structure of cases of relationship of diseases of CWs that led to death, the share of AH was 17.8 %. In CWs the main group the AH developed in (9.4 ± 6.2) years after participation in WLAc, which is on average 6 years earlier than in the comparison group (р < 0.001). AH in the main group of CWs developed at the age of 5.8 years younger than in the comparison group (р = 0.0005). The need for inpatient treatment come 8.6 years earlier (14.6 ± 7.7 years) than in CWs comparison group (р < 0.001). At DERE 0,05 Sv and over, increases the probability of development and progression of AH that has causal relationship with participation in the WLAc. For medical expertise of the causal relationship of the AH development and progression with WLAc at DERE 0.20 Sv and over the significant evidence value have the next criteria: terms Somatoform Vegetative (autonomic) Dysfunction (SVD) development (within 3,5 years) and its transformation into AH (within 7 years), verification of the AH diagnosis (within 9,5 years), inpatient treatment for SVD or AH (within 15 years), vascular events (Acute Cerebrovascular Accident – Stroke (ACVA) – within 24 years after participation in the WLAc or 11 years after the AH diagnosed, myocardial infarction (MI) – within 22 years after participation in the WLAc or 10.5 years after the AH diagnosed), the establishment of permanent disability. Conclusion: Radiation factor has an evidence influence on the development and progression of AH in CWs. Criteria of the development and progression of AH in CWs can be used for evidence-based medical expertise for estimation of the causal relationship of the disease with the WLAc in the remote post accidental period at DERE more than 0.20 Sv. Key words: ionizing radiation, arterial hypertension, clean-up workers of Chornobyl NPP accident, medical expertise, Chornobyl catastrophe.

Antifibrinolytic therapy in the clinic for miscarriage – aspects of medical tactics

2017 ◽  
pp. 78-82
Author(s):  
V.I. Pyrohova ◽  
◽  
O.O. Oshurkevich ◽  
Keyword(s):  
Single Dose ◽  
Comparison Group ◽  
Effective Means ◽  
First Trimester ◽  
Main Group ◽  
Symptomatic Therapy ◽  
Second Trimester ◽  
Duration Of Treatment ◽  
Antifibrinolytic Therapy ◽  
First Choice

The objective: to evaluate the efficacy of tranexamic acid (Tranexam drug) accompanied by pregnancy with a partial detachment of a normally located placenta in the second trimester of pregnancy in women with a history of obstetrical gynecological anamnesis. Patients and methods. Under observation were 75 patients with complicated retrochorial hematoma at first trimester of pregnancy, re-hospitalized at the time of 18–21 weeks with signs of premature placental abruption. The blind method of the patient was randomized into two groups (baseline and comparison), which differed in the type of haemostatic therapy. Clinical groups were formed by age (26.5±0.8 and 27.4±1.1 years, respectively), parity, gestational age, somatic and obstetric-gynecological history, localization and approximate sizes of retroplacental hematomas were comparable. Patients from both groups received sublingual micronized progesterone at a dose of 200 mg, anti-anemia and symptomatic therapy according to indications. In the main group, 45 pregnant women received a haemostatic therapy with the drug Tranexam (Stada): 750 mg at a single dose at a single dose of 1500 mg for 5 to 7 days before bleeding stopped. 30 patients, who underwent haemostatic therapy with sodium etamzilate in a complex of therapeutic measures, made a comparison group. The duration of hemorrhage from the genital tract, the regression of the retrohorial hematoma, the length of stay in the hospital, the prolongation and the consequences of pregnancy were estimated. Results. Clinically, a decrease in the intensity of bleeding with Tranexam was observed 24.6±2.1 hours after the initial dose, bleeding duration averaged 3.5±0.3 days, whereas in the group taking sodium etamzilate, the bleeding time was significantly longer – 4.9±0.2 days (p<0.05). These data correlated with ultrasound data confirming the absence of progression of retrochorial hematomas from the second day with the use of Tranexam in 34 (75.6%) of the women in the main group, whereas in the comparison group, similar changes occurred at the same time in only 10 (33.3%) of patients (p<0.5). The faster stopping of bleeding and, as a consequence, the organization and resorption of hematomas in the region of placental detachment in a shorter period affected the effects of pregnancy (the frequency of preterm labor in the comparison group occurred 2.2 times more often than in the main group). Conclusion. Taking into account the peculiarities of the physiological mechanisms of the functioning of the fibrinolytic system during the gestation period and the significance of their disturbances in the genesis of early and late gestational bleeding allows us to choose the most effective therapeutic tactics. Tranexam in effective daily doses with course duration of treatment of 5–7 days gives a pronounced haemostatic effect, does not cause side effects, and allows successfully prolonging the pregnancy and reducing the frequency of late gestational complications. Inclusion in the treatment complex of patients with recurrence of retroplacentar hematomas and formation of partial placental detachment in the second trimester of gestation of the preparation of antifibrinolytic action to Tranexam is an effective means not only to stop bleeding, but also to preserve pregnancy, prevent the formation of placental insufficiency and ensure favorable pregnancy outcomes. Accumulated experience allows attributing Tranexam to the drugs of the first choice in the clinic for miscarriage and recommending it for widespread use in practice. Key words: retroplacentar hematoma, pregnancy, antifibrinolytic therapy, Tranexam.

scholarly journals Effectiveness of Physical Therapy in the Correction of Respiratory System Dysfunction Signs in Women with Abdominal Obesity

2020 ◽  
Vol 5 (5) ◽  
pp. 248-257
Author(s):  
M. G. Aravitska ◽  
Keyword(s):  
Body Weight ◽  
Physical Therapy ◽  
Abdominal Obesity ◽  
Respiratory System ◽  
Comparison Group ◽  
Main Group ◽  
Blood Oxygenation ◽  
Obese People ◽  
Low Level ◽  
Arterial Blood

Respiratory disorders in obesity occur even in the absence of bronchopulmonary pathology, and in their presence, an excess of adipose tissue worsens the prognosis of the disease. Obese people have a high risk of obstructive sleep apnea syndrome, hypoventilation syndrome, bronchial hyperreactivity, pneumonia, pulmonary hypertension. The purpose of the study was to determine the effectiveness of using physical therapy in the correction of signs of respiratory system dysfunction in women with abdominal obesity. Material and methods. The study involved 172 women with abdominal obesity of I-III degrees, diagnosed by body mass index and the ratio of waist and hip circumferences. According to the results of the definition of the rehabilitation (therapeutic) alliance, they were divided into two groups. The comparison group consisted of women with a low level of alliance that refused to actively participate in the program of weight loss. The main group consisted of women with a high level of alliance; they underwent a one-year correction program using nutritional modification, increased physical activity, lymphatic drainage, psychocorrection, and elements of respiratory physical therapy. The control group consisted of 32 women with normal body weight. Subjective state, dyspnea intensity, pulsоoximetry and spirometry parameters were studied. Results and discussion. We revealed the respiratory system dysfunction in women with abdominal obesity: subjective signs of impaired respiratory function, a decrease in arterial blood oxygenation, and a decrease in spirometry volumes. Their content and severity were proportional to the severity of obesity. Using respiratory therapy elements in the program of complex physical therapy aimed at reducing body weight let us normalize the studied parameters of the respiratory system function in women of the main group. The low level of the rehabilitation alliance of women in the comparison group led to unsatisfactory implementation of the recommendations provided and was associated with a lack of rehabilitation effect. Improvement in the state of the bronchopulmonary system in women with abdominal obesity is justified both by primary changes in the respiratory system – an increase in spirometry volumes and reserves, improved blood oxygenation, and indirectly – by an increase in the range of motion of the diaphragm, a decrease in the amount of visceral fat and general fitness, which is confirmed by the leveling of signs of restrictive and mixed respiratory failure. Conclusion. It is advisable to include the elements of respiratory rehabilitation in the programs for restoring the health of women with abdominal obesity

scholarly journals ANATOMIC-FUNCTIONAL STATE OF PELVIC ORGANS IN WOMEN WITH INFERTILITY AND OVARICOVARICOCELE

2020 ◽  
pp. 52-57
Author(s):  
Astakhova OlenaVasylivna ◽  
Hryhorenko Andrij Mykolajovych ◽  
Malinina Olena Bohdanivna ◽  
Taran Oksana Anatoliivna
Keyword(s):  
Menstrual Cycle ◽  
Functional State ◽  
Comparison Group ◽  
Ultrasound Examination ◽  
Varicose Veins ◽  
Morphological Changes ◽  
Pathological Process ◽  
Main Group ◽  
Pelvic Organs ◽  
Yellow Body

Introduction. High informativeness and accessibility of ultrasound examination in infertile patients provides for the exclusion or confirmation of morphological changes in genitals, the degree of damage to the organ and the involvement structures, in particular, varicose veins of the gonadal veins, which can be explained by the emergence of ovarian dysfunction. In addition, the polymorphism of semiotics of echographic signs of pathological changes in pelvic organs in the examined patients confirms the complexity of determining the main and concomitant etiological factors of the emergence of functional infertility in women, the development of disorders of reproductive function and causes the need to involve other methods. The aim of the work was to study the anatomical and functional characteristics of the pelvic organs by ultrasound, medical diagnostic laparoscopy and hysteroscopy to determine the degree of morphological changes of the genitals in women with infertility and ovaricovaricocele. Materials and methods. To solve the goals and objectives, 117 pregnant women of reproductive age (21-44 years old) with functional infertility were prospectively examined and divided into 2 groups for the comparative analysis: the main group was 62 women with infertility and varicose veins in the ovaries; a comparison group was 55 women with infertility without varicose veins. The study of the anatomical and functional state of the uterus, ovaries and fallopian tubes in women of the studied groups was performed by standard ultrasound examination on the PHILIPS ATL-HDI 4000, PHILIPS HD 11-XE with the analysis of folliculogenesis. Laparoscopic intervention was performed by the patients of the main group on the apparatus "Karl Storz" (Germany) in the first phase of the menstrual cycle. Diagnostic hysteroscopy in order to clarify the state of the uterus and endometrium was performed simultaneously with laparoscopy in the 1st or 2nd phase of the menstrual cycle using the equipment "Karl Storz" (Germany).Results. In women of the main group with a combination of functional infertility and ovaricoaricocele, there is a statistically significant increase in the percentage of incorrect position of the uterus - 36 (58.1%) in normal form and size of the uterus, both in the main group of women and in the comparison group - 53 (85,5%) and 48 (87.3%) cases respectively. Analyzing the indicators of ovarian size and the number of antral follicles, a statistically significant difference was found in the direction of its reduction in women with functional infertility and ovaricovaricocele women without varicose dilatation of ovarian veins - 4.1 ± 0.1 cm3 vs. 5.8 ± 1 , 4 cm3 and 3.9 ± 1.1 versus 5.6 ± 1.4, respectively, in two groups. In addition, there is a tendency to reduce the size of the ovary of the protradiental age in women of all the studied groups with statistically significant rates in the patients of the main group. Also, there is a difference in the right ovary volume relative to the left in women with infertility and ovaricovaricocele in the direction of decreasing the size of the latter, which may be due to the predominant localization of the enlarged gonadal vein, and this difference is statistically significant. In determining the functional state of the ovaries in the overwhelming number of women in all of the studied groups ovulation was noted, however, when studying the characteristics of the functional state of the yellow body according to echographic signs, decrease in the thickness of the endometrium in the middle of the luteal phase of the menstrual cycle in patients of the main group, as well as the absence in the overwhelming majority cases of its adequate secretory changes, which is statistically significant against the women of the comparison group. In patients, both the main group and the comparison groups, there is a decrease in the ratio of the volume of the yellow body and ovarian volume and the decrease in the thickness of the wall of the yellow body, respectively, against the control group women, which is an ultrasound sign of inferiority of the yellow body and lack of luteal phase of the menstrual cycle. In addition, women in the main group have a statistically significant reduction in the rates against the women in the comparison group. In women of the main group, a large percentage of varicose veins of the small pelvis are found in the absence of organic changes in the uterus and adnexies (73.3%) in the presence of infertility of obscure genesis.Conclusions. Ultrasound study in combination with color Doppler of patients with ovaricovaricocele is a highly informative method of research, because it allows to perform topical diagnosis, to determine the morphological character of the lesion, to differentiate the type of pathological process and to identify the concomitant pathology of the pelvic organs. The conducted study suggests that ovaricovaricocele should be considered not only as an accompanying symptomatic changes in diseases of the female genitals, but also as one of the causes of ovarian dysfunction with delay or termination of growth of the follicles, change in their size, degenerative-dystrophic changes in the ovaries, which leads to a violation hormonal homeostasis and manifested by reproductive disorders. In the perspective of further research it is necessary to consider a complex analysis of the morphological and functional characteristics of the internal genital organs, which will establish the presence of a certain functional and organic gynecological pathology and will enable to diagnose the initial and minimal course of the pathological process of the pelvic organs, finally verify the final diagnosis and appoint pathogenetic treatment.

Thromboembolic complications prevention in the obstetric practice

2017 ◽  
pp. 19-24
Author(s):  
O.V. Grishchenko ◽  
◽  
V.V. Bobrytska ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Comparison Group ◽  
Main Group ◽  
Control Group ◽  
Efficacy And Safety ◽  
Thromboembolic Complications ◽  
Moderate Risk ◽  
Obstetric Practice ◽  
Thrombotic Complications ◽  
And Control

The objective: To evaluate the clinical efficacy and safety of Enoxaparin-Pharmex for the prevention of thrombotic complications (pulmonary embolism) in the postoperative period in patients with moderate risk of these complications. Patients and methods. The study included 50 women after a caesarean section had an average degree of risk of pulmonary embolism. Patients were divided into the main group (n=25) and control group (n=25) in accordance with the treatment: patients of the main group received postoperative Еnoxaparin- Pharmex, group comparisons enoxaparin sodium (brand foreign manufacturer’s). Patients in both groups received the drug at a dose of 20 mg for 5 days, 1 time per day subcutaneously. Results. The research data analysis showed identity results of hemostasiogram of patients in the main group and the comparison group, no side effects after treatment in both groups. Conclusion. The clinical studies suggest the drug Enoxaparin-Pharmex is effective, safe LMWH, which can be used to prevent troboembolic complications, including post-operative treatment in obstetric practice. Spectrum of Enoxaparin-Pharmex can be extended to the prevention and treatment of thromboembolic conditions of varying severity with appropriate doses of the drug. Key words: Enoxaparin-Pharmex, prevention of pulmonary embolism.

Suspension training classes as an effective means to reduce the bodyfat level in middle-aged women

2020 ◽  
Vol 71 (2) ◽  
Author(s):  
Zinaida M. Kuznetsova ◽  
Aleksandr S. Kuznetsov ◽  
Roman S. Nagovitsyn ◽  
Stanislav A. Kuznetsov ◽  
Olga G. Maksimova ◽  
...  
Keyword(s):  
Effective Means ◽  
Middle Aged

Assessment of the impact of factors of the working environment on the health of workers in oil refining based on the analysis of morbidity

2020 ◽  
pp. 600-600 ◽  
Author(s):  
I. V. Ginko ◽  
T. M. Sushinskaya ◽  
A. L. Rybina
Keyword(s):  
Comparison Group ◽  
Main Group ◽  
Working Environment ◽  
Oil Refinery ◽  
Oil Refining ◽  
Production Environment ◽  
The Impact

Studies have been conducted to assess the impact of factors of the production environment on employees of the oil refinery ofJSC «Naftan». Significant differences with the comparison group on the indicators of SVT were revealed. Priority nosological forms of employees of the main group are identified.

Surgical treatment of patients with deep infiltrating endometriosis of the rectovaginal septum

2021 ◽  
Vol 20 (4) ◽  
pp. 5-11
Author(s):  
E.A. Galliamov ◽  
◽  
L.N. Aminova ◽  
V.A. Alimov ◽  
A.G. Kozub ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Pelvic Pain ◽  
Chronic Pelvic Pain ◽  
Comparison Group ◽  
Chronic Pelvic Pain Syndrome ◽  
Main Group ◽  
Pelvic Pain Syndrome ◽  
Deep Infiltrating Endometriosis ◽  
Rectovaginal Septum ◽  
Infiltrating Endometriosis

Objective. To optimize the tactics of surgical treatment of deep infiltrating endometriosis of the rectovaginal septum, including with bowel involvement. Patients and methods. The study included 122 patients diagnosed with deep infiltrating endometriosis of the rectovaginal septum, who underwent surgical interventions of different volumes using laparoscopy. The patients were divided into a main group and a comparison group. The main group consisted of 92 patients with deep infiltrating endometriosis of the rectovaginal septum who underwent surgical treatment using the original technique of systematic approach; the comparison group consisted of 30 patients who were operated using the generally accepted technique. Results. There was a statistically significant decrease in the operation duration, intraoperative blood loss, as well as more effective relief of dysmenorrhea and chronic pelvic pain syndrome, less complications and relapses in the main group compared to the comparison group. In addition, it was found that the combination of three symptoms such as dysmenorrhea, dyspareunia and chronic pelvic pain increase the likelihood of deep infiltrating endometriosis up to 93%. Conclusion. Based on the results obtained, the proposed method of surgical treatment of deep infiltrating endometriosis is more efficient and safer in comparison with the generally accepted technique, which can be considered as a valid reason for its wide introduction into clinical practice. Key words: deep infiltrating endometriosis, bowel endometriosis, surgical treatment of endometriosis, treatment algorithm

PECULIARITY OF ADAPTATION OF BABIES ARE BORN PREMATURELY FROM MOTHERS WITH UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA

2021 ◽  
Vol 74 (10) ◽  
pp. 2566-2568
Author(s):  
Tunzala V. Ibadova ◽  
Vitalii V. Maliar ◽  
Volodymyr V. Maliar ◽  
Vasyl V. Maliar
Keyword(s):  
Connective Tissue ◽  
Premature Infants ◽  
Distress Syndrome ◽  
Comparison Group ◽  
Clinical Manifestations ◽  
Main Group ◽  
Phenotypic Markers ◽  
Group I ◽  
Neonatal Respiratory Distress ◽  
Connective Tissue Dysplasia

The aim: To evaluate the peculiarity of clinical manifestations of neonatal respiratory distress syndrome (NRDS) in deeply premature infants from mothers with phenotypic markers of undifferentiated connective tissue dysplasia (UCTD). Materials and methods: The study represent the results of a retrospective clinical and statistical analysis of 268 premature birth report card and newborn report sheet. .The main (1 group) included 50 pregnants with obvious phenotypic markers of UCTD, the comparison group (group 2) consisted of 50 pregnant women without phenotypic markers of UDCTD. Results: According to the study, in 12 (24%) pregnant women of the main group at the time of admission to the clinic had contractions,which required specific therapy. Cervical cerclage was performed in 38 (76%) patients of the main group due to the presence of cervical insufficiency (CI). In these cases, the severity of the CI on the Steinber scale was 7.2 &#177; 0.4 points in the main group against 4.4 &#177; 0.2 points in the comparison group (p &#60;0.05). Group I patients were more likely to have complications of labor such as:premature rupture of membranes, uterine contraction abnormalities and fetal distress, which required in most cases cesarean delivery (7% and 2%), respectively (p &#60;0.05). The incidence of neonatal complications requiring respiratory support was 67% in group I and 48% in group II. According to our observations, the clinical manifestations of bronchopulmonary dysplasia were twice as high in infants of the main group (66%) against (44%) of the comparison group (p &#60;0.05). Conclusions:1.Neonatal respiratory distress syndrome in premature infants is more often associated from mothers with UDCTD. 2. The high importance of steroid prophylaxis of NRDS and antioxidant therapy in reducing the frequency of mechanical ventilation and the development of bronchopulmonary pathology, especially in infants from mothers with UDCTD syndrome, has been proven. 3. The possibility of diagnosing disorders of functional maturation of the lungs in the fetal period using a non-invasive method of ultrasonography has been confirmed.

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