scholarly journals Epidemiological analysis and investigation of +114G/T polymorphism in the gene IL-2 in patients with breast cancer in the state of Mato Grosso

Mastology ◽  
2017 ◽  
Vol 27 (4) ◽  
pp. 334-338
Author(s):  
Silvia Barassuol Sommavilla ◽  
◽  
Aguiar Farina ◽  
Danebe Fernandes de Araújo ◽  
Bianca Borsatto Galera ◽  
...  
2020 ◽  
Vol 45 (2) ◽  
pp. 340-348
Author(s):  
James Lucas da Costa-Lima ◽  
Earl Celestino de Oliveira Chagas

Abstract—A synopsis of Dicliptera (Acanthaceae) for Brazil is presented. Six species are recognized: Dicliptera ciliaris, D. sexangularis, and D. squarrosa, widely distributed in South America; D. purpurascens, which ranges from the North Region of Brazil (in the state of Acre) to eastern Bolivia; D. gracilirama, a new species from the Atlantic Forest of northeastern Brazil; and D. granchaquenha, a new species recorded in dry and semideciduous forests in Bolivia and western Brazil, in the state of Mato Grosso do Sul. Furthermore, we propose new synonyms and designate lectotypes for eleven names. An identification key to the six accepted Dicliptera species in Brazil is provided.


Author(s):  
Yasmine Mohamed Elsaeid ◽  
Dina Elmetwally ◽  
Salwa Mohamed Eteba

Abstract Background This prospective study included 65 female patients with primary breast cancer. Ultrasound was performed for all patients. Ultrasound findings were analyzed according to the ACR BI-RADS lexicon 5th edition and correlated with tumor type, grade, and biological markers (ER, PR, HER-2/neu, and Ki67). The purpose of this study is to assess the association between ultrasound findings, tumor type, grade, and the state of biological markers in patients with breast cancer. Results Irregular shape and speculated margins are more frequently associated with invasive duct carcinoma than DCIS (p value < 0.001). There were no association between the ultrasound findings (shape, margin, orientation, echopattern, and posterior features) and the tumor grade (p value 1.0, 0, 0.544, 1.0, and 1.0), respectively. Irregular shape is more frequently seen in ER and PR positive breast cancers (p value = 0.036 and 0.026, respectively). Non-circumscribed margins were frequently seen in PR positive breast cancers (p value = 0.068). No statistically significant difference between US descriptors and HER-2/neu-positive cases. Conclusion Irregularly shaped tumors with speculated margins are frequently seen in invasive duct carcinoma and also more frequently seen in ER-, PR-, and Ki67-positive cases. No relation between ultrasound descriptors and the tumor grade of invasive duct carcinoma. Also, there were no relation between ultrasound descriptors and the state of HER-2/neu.


2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e12599-e12599
Author(s):  
Hyein Jeon ◽  
Myeong Lee ◽  
Mohammed Jaloudi

e12599 Background: Higher prevalence of triple negative breast cancer (TNBC) in black women with associated poor outcomes due to various disparities is well documented within a single state. We examine multiple states to better understand the state effect on such differences in incidence and prevalence of TNBC in black women. Methods: Female patients of ages 19 years old and above with breast cancer from the Surveillance, Epidemiology and End Results (SEER) Program across 13 states (608 counties) from 2015 (n = 66,444) and 2016 (n = 66,122) were examined. The relationships between the proportion of black and white women and the rate of patients with different tumor subtypes (luminal A, luminal B, HR-HER2+, and triple negative) were examined at the county level using ordinary least-square regression models. In parallel, due to consideration of various state-specific healthcare policies, socio-cultural norms, and socio-economic disparities, multi-level regression models were applied to examine the nested, random effect of each state on TNBC prevalence in each county. Bonferroni correction was applied to reduce the Type I error caused by repeated use of the same variables in multiple tests. Results: The baseline breast cancer rates between black and white women were similar in the population (0.171% for black and 0.168% for white). Consistent to previous studies, we demonstrate a significant positive correlation (p < 0.001) in TNBC in black females in both years. Surprisingly, when accounted for the random effects on states, 38.2% (2015) and 34.3% (2016) increase in incidence of TNBC in black females were seen, suggestive of state-specific disparity affecting race-specific health. In 2015, other subtypes of breast cancer in both black and white females did not result in significant relationship. Interestingly, in 2016, there was a significant relationship seen between the TNBC rate in white females and the white female population rate only after adjusting for the state effect (p = 0.026). This indicates the impact of non-biological factors such as state-wide health policies. Additionally, HR-HER2+ black females had a significant relationship against respective population rate only after adjusting for the state effect as well (p = 0.0394). For luminal A white females, a 15% decrease in incidence was seen after adjusting for state effect (p = 0.0424). Conclusions: This is the first known across-state examination of breast cancer subtypes by race with random effects on state. This study shows the role of state-specific factors affecting incidence in black and white females and potentially indicates the importance of state-level management for breast cancer on health disparities in addition to race-driven effects. Further studies are needed to elucidate comparable differences between states affecting the rates of various subtypes of breast cancer and thus health outcomes.


Author(s):  
Rute Witter ◽  
Hilda Fátima Jesus Pena ◽  
Maerle Oliveira Maia ◽  
Leodil da Costa Freitas ◽  
Sayanne Luns Hatum Almeida ◽  
...  

Author(s):  
Mariana de Moura Queiroz ◽  
Sidney Fernando Caldeira ◽  
Alexandre Magno Sebbenn ◽  
Daniele Aparecida Alvarenga Arriel

Zootaxa ◽  
2021 ◽  
Vol 4933 (1) ◽  
pp. 98-112
Author(s):  
CLÁUDIO H. ZAWADZKI ◽  
GABRIELA NARDI ◽  
LUIZ FERNANDO CASERTA TENCATT

The menaced and poorly-known waters of the Bodoquena Plateau revealed a new resident, the stunning Hypostomus froehlichi sp. n., a large-sized armored catfish, which is finally described after more than twenty years since its discovery. The Bodoquena Plateau is drained by the rio Paraguay basin, and is located in the state of Mato Grosso do Sul, Brazil. The new species differs from its congeners on the Bodoquena crystalline waters by having teeth with morphological and numerical variation in adult specimens. There is a continuous range of specimens having about 20 thick and worn teeth to specimens having about 50 thin teeth with intact crowns and lanceolate main cusps. Additional diagnostic characters are: dentaries angled more than 90 degrees, dark blotches, one plate bordering supraoccipital, moderate keel along dorsal series of plates, usually two rows of blotches per interradial membrane on dorsal, pectoral and ventral fins, and by attaining comparatively large size. Hypostomus froehlichi seems to be endemic to the area of the Bodoquena Plateau, in rivers draining to the rio Miranda. The description of the new species reveals a potential conservation flagship species as it is one of the most seen and documented fish by visitors and divers in the clear waters from the touristic, though menaced, Bonito region in Brazil. 


PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205253 ◽  
Author(s):  
Sheila Cristina Rocha-Brischiliari ◽  
Luciano Andrade ◽  
Oscar Kenji Nihei ◽  
Adriano Brischiliari ◽  
Michele dos Santos Hortelan ◽  
...  

2017 ◽  
Vol 37 (7) ◽  
pp. 662-666
Author(s):  
Flávio H.B. Caldeira ◽  
Geovanny B.G. Dias ◽  
Felipe P. de Arruda ◽  
Valdecy de M. Lourenço ◽  
Kalinne S. Bezerra ◽  
...  

ABSTRACT: The aim of this study was to investigate the importance of an acute disease that was characterized by sudden death associated with exercise that affected cattle in the region of the Araguaia River, especially in the municipality of Torixoréu, southeastern Mato Grosso, Brazil. Between August and September 2013, eighty farms in the municipality were visited and the pastures of these farms were inspected. Epidemiological questionnaires were completed from 65 farms. A plant identified as Niedenzuella stannea (N. stannea) of the Malpighiaceae family was attributed to the cause of sudden death in cattle, what causes major economic losses. Sudden death reports have occurred since 1970, when livestock was introduced into the region, and sudden death reports still occur. Outbreaks were reported to occur from May to October, but mainly during the dry season between June and August. N. stannea was identified at 41 farms and was always found in near to rivers. The most effective plant control methods included plowing the pastures and fields followed by manual application of Tordon® (Picloram and 2.4D). The administration of 5g/kg of young leaves which were collected from a farm with a sudden death history in cattle also caused sudden death in a sheep. Thus, it is concluded that the sudden death of cattle in the region of the Araguaia River is caused by the consumption of N. stannea.


2014 ◽  
Vol 109 (6) ◽  
pp. 820-823 ◽  
Author(s):  
Nayara Zuchi ◽  
Letícia Borges da Silva Heinen ◽  
Marcelo Adriano Mendes dos Santos ◽  
Fernanda Carla Pereira ◽  
Renata Dezengrini Slhessarenko

Sign in / Sign up

Export Citation Format

Share Document