scholarly journals DENGUE FEVER

2018 ◽  
Vol 21 (02) ◽  
pp. 243-246
Author(s):  
Muhammad Naeem ◽  
Aneela Shaheen ◽  
Saima Batool ◽  
Sara Rubab ◽  
Tehmina Saba ◽  
...  

Background: Dengue is the most prevalent mosquito-born viral illness in theworld. Clinically dengue ranges from asymptomatic, non-febrile illness, classic dengue todengue hemorrhagic fever/dengue shock syndrome. Objective: Subjects & Methods: Thisstudy was included 79 patients conducted at Nawaz Sharif Social Sevurity Hospital, Lahoreduring the epidemic of dengue in Lahore from September 2011 to Dec 2011. Results: Twenty outof 79 patients suspected of dengue fever were dengue IgM positive. Male to female ratio was1.19: 1. Our study included 79 patients suspected of having dengue fever. Fever was the mostcommon symptom in these patients. Conclusions: Early identification of dengue with risk ofdeveloping hemorrhage is an important clinical objective. The morbidity and mortality can bereduced by appropriate and judicious treatment of dengue patients.

2015 ◽  
Vol 24 (Number 1) ◽  
pp. 3-7
Author(s):  
A H M Karnal ◽  
K H Mollah ◽  
A Begum ◽  
K Khoda ◽  
S Tanzeem ◽  
...  

Dengue is a rapidly spreading mosquito-borne viral disease worldwide. The endemicity in Bangladesh is also increasing gradually. The study was a prospective observational one, documented the presenting features and outcome of management. It was carried out in Department of Medicine in Holy Family Red Crescent Medical College Hospital, Dhaka from June 2013 to December 2013. Total 100 admitted cases of both sera positive and sera-negative were included in this study. Detailed history was taken, clinical examination and relevant investigations were done. Out of 100 patients 54 (54%) were male and 46 (46%) were female. So male to female ratio was 1.7:1. The age of the patients ranged from 12-75 years. Among them 20-40 years age group was highest 63%. Patients of higher socio-economic group were (69%) more affected. Out of 100 cases 54 had classical dengue fever (DF), 46 had dengue hemorrhagic fever (DHF). Antibody was positive in 81% cases. All patients presented with high fever, headache in 90%, retro-orbital pain in 45%, body ache in 56%, and backache in 48%. Leucopenia found in 60, platelet count <100x1091L was in 57, HCT- normal 17, <20% rise in 48%, ?20% rise in 28%. With proper management all patients were recovered.


2021 ◽  
Vol 8 (4) ◽  
pp. 631
Author(s):  
S. V. S. Sreedhar ◽  
Ramishetty M. Umamahesh

Background: Dengue viral infection is the most common mosquito-borne disease in the world with varied presentations, high morbidity, and high mortality patterns. To study the clinical profile and outcome of dengue fever in children.  Methods: This analytical study was conducted in children less than 12 years of age with clinical features of dengue (any acute febrile illness with one of the following: myalgia, headache, retro-orbital pain, bleeding, altered sensorium, shock, or low platelet count) presented at Mahavir institute of medical sciences between February 2019 to January 2020 (12) months were included in the study. Children positive for IgM alone or both IgM and IgG were followed up for a clinical profile.Results: Seizures (9.5%), loose stools (8.5%), lymphadenopathy (15.2%), relative bradycardia (8.5%) were less common manifestations. Rashes were seen in 64.7% of children. Many children in this study were mildly anemic. Mean hemoglobin was slightly higher in dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Mean Hb in DSS was 11.28 g%. It was 10.02, 10.1, and 10.45 in DF, DFB, DHF respectively. But it was statistically not significant (P=0.27).Conclusions: Seizure was significant in DSS cases. Any dengue child throwing convulsions should hence be promptly evaluated for an unrecognized shock. The bleeding in dengue is not purely due to thrombocytopenia. There is no role for prophylactic platelet transfusion.


Author(s):  
Ramalingam Kothai ◽  
Balasubramanian Arul

Dengue fever is a disease caused by a family of viruses transmitted by mosquitoes. Dengue virus (DENV), a member of the Flaviviridae family, causes the most widespread mosquito-borne viral infection in humans around the world today. Dengue can affect anyone but tends to be more severe in people with compromised immune systems. Dengue hemorrhagic fever is a more severe form of a viral illness. Symptoms include headache, fever, rash, and evidence of bleeding (hemorrhage) in the body. This form of dengue fever can be life-threatening and can progress to the most severe form of the illness, dengue shock syndrome. This chapter reviews the etiology, epidemiology, diagnosis, pathophysiology, transmissions, manifestations, diagnosis, treatment, and prevention of dengue.


2017 ◽  
Vol 24 (10) ◽  
pp. 1466-1470
Author(s):  
Wasil Khan ◽  
Bacha Amin Khan ◽  
Zar Khan ◽  
Abid ur Rehman ◽  
Mohammad Akbar ◽  
...  

Introduction: Dengue fever is arboviral infection transmitted from infected personto non-infected one by mosquitoes Aedes Aegypti or Aedes albopectis. All four serotypes (DEN-1, DEN-2, DEN-3 & DEN-4) can cause the clinical manifestations of disease. Dengue infectioncan cause acute febrile illness, dengue hemorrhagic fever (DHF) and dengue shock syndrome(DSS). About 50-100 million cases of dengue fever reported annually worldwide in which 0.5million may need admission. Overall mortality of dengue fever is 3%. The diagnosis of dengueis established by classical clinical features along with specific investigations like PCR, detectionof dengue NS1 antigen or IgM or IgG antibodies in the blood of infected person. Dengue isendemic in most part of our country and can become epidemics on and off. Objectives: Tostudy the pattern and mortality of Dengue fever during epidemic and post epidemic years inSwat. Setting: This study was conducted in Medical Department of Saidu Group of TeachingHospital, Swat. Period: Aug 2013 to November, 2016. Patients and method: Patients sufferingfrom acute febrile illness with features suggestive of Dengue fever were included in the study.Clinical criteria for initial diagnosis directed the subsequent diagnostic work up. Dengue wasconfirmed in these patients by either Dengue NS1 or Ig M antibodies in their blood. Writtenconsent for participation in study was taken from all the included patients. Formal permissionwas taken from Institutional Review Board of the institution to perform this study. The clinical andlaboratory data were recorded on a proforma and analyzed using SPSS 20. Results: Among5569 patients, 3834 (68.85 %) were male and 1735 (31.15%) were female. The mean age ofthe patients was 30 years SD 15.20. The most common age group that suffered with Denguefever was the adult age group (13-30 years). Dengue Hemorrhegic Fever was diagnosed in2543 (45.6%) patients and 50 (0.89 %) had features of DSS. A total 5018 (90.1 %) patients werecompletely cured while 37 (0.66 %) patients died. The overall mortality was 0.66%. Patientswith Dengue fever presented to the hospital though out the year but more than 50% of caseswere reported in the month of September. Conclusion: Adult age group and male gender ismost commonly affected by Dengue fever. Dengue fever was endemic in Swat valley and it canbecome cyclic epidemic in post epidemic years. Dengue fever can claim so many preciouslives if proper preventive measures were not taken in future.


2017 ◽  
Vol 4 (1) ◽  
pp. 218 ◽  
Author(s):  
E. Chandra Shekar ◽  
. Laxminarayana ◽  
B. Kishan ◽  
Suresh Kumar ◽  
Bikshapati Rao

Background: Dengue is the most common mosquito borne endemo-epidemic arboviral infection in many of the tropical and subtropical regions of the world. Dengue virus (DEN) is a small single-stranded RNA virus comprising of four distinct serotypes (DEN-1 to -4). Dengue virus infections were grouped into three categories: undifferentiated fever, dengue fever (DF) and dengue haemorrhagic fever (DHF). This study was done to analyze the clinical, biochemical and hematological parameters of dengue fever.Methods: 100 patients admitted to AMC / IMC / WARDS of Mahatma Gandhi Memorial Hospital Warangal, Telangana, India during the period November 2012 - October 2013, presenting with acute febrile illness who are IgM seropositive for dengue and satisfying inclusion and exclusion criteria. Patients belonging to the age group of above 12 years, belonging to both sexes were selected and included in the study group.Results: A total of 100 patients admitted to our hospital with fever and IgM dengue positive were studied. Out of 100 patients, 81 (81%) patients were diagnosed to have DF. 10 (10%) patients were diagnosed to have dengue hemorrhagic fever (DHF) and 9 (9%) patients were diagnosed to have dengue shock syndrome (DSS) based on WHO criteria. The present study included 53 (53%) male patients and 47 (47%) female patients. Male to female ratio is 1.13:1.Conclusions: In our study classical dengue fever was the most common clinical presentation followed by complicated forms such as dengue hemorrhagic fever and dengue shock syndrome. On investigation deranged liver function tests, renal function tests, ascites, hepatospleenomegaly on ultrasonography and pleural effusion on chest radiography are more commonly seen in patients with DHF and DSS. Platelet count does not correlate with the severity of the disease.


Author(s):  
Vijay Kumar Meena ◽  
Shyam Bihari Meena ◽  
S. R. Meena

 Background: Dengue fever is one of the most common arboviral mediated outbreaks reported with increased prevalence year after year with considerable morbidity and mortality in hadoti region. the aim to study various clinical and laboratory manifestations of Dengue fever admitted in MBS Hospital KOTA, with a diagnosis of Dengue fever according to WHO protocol from December 2018 to January 2020.Methods: Prospective observational study was undertaken among adult patients. 132 patients were studied and analysed. And diagnosis was confirmed with Dengue IgM ELISA test. Other routine investigations done were routine hematological and biochemical investigations.Results: A total of 132 cases, out of which 95 cases of Dengue Fever (DF), 34 cases of dengue hemorrhagic fever and 3 cases of Dengue Shock syndrome, out of which Male: Female ratio was 2.1. and mean age of presentation was 37. Fever and myalgia were the most common finding (100%) followed by arthralgia and headache. Pruritus was found in 21 cases (15.9%) which carried a significant difference between DF and DHF (p value <0.05). Among the laboratory features, thrombocytopenia and hematocrit were found to be statistically significant in DHF patients (p value <0.05). Mean platelet count was 0.71 lakhs/mm3. Leukopenia in 40(30.3%) cases. Raised Serum Aminotransferase level, AST (>40 IU/L) was seen in 39 cases (29.54%.). Pleural effusion was seen in 4 cases (3%), of which 3 cases of DHF and 1 case of DSS. Ascites in 6 cases (4.8%), all cases belong to DHF. Gall bladder wall thickening was seen in 28 cases (21.21%) of which 20 cases (54.04%) were of DHF. Melena was the most common bleeding manifestation. Skin rash was found to be positive in 40.5% cases. Hess test was positive in 4 cases (10.8% of DHF).Conclusions: Incidence of dengue fever is on the rise in hadoti region and one of the most important differential diagnosis of patients presenting with fever during monsoon and post monsoon seasons.


2021 ◽  
pp. 50-52
Author(s):  
Rukuzo Nyeka ◽  
Indraneel Dasgupta

Introduction: Dengue fever is a mosquito-borne viral disease caused by a avivirus. There are four distinct serotypes of dengue virus, namely DEN-1, 2, 3 and 4. Female Aedes aegypti and Aedes albopictus mosquitoes are the primary and secondary vectors in Malaysia, respectively. Evidently, dengue is the most rapidly spreading arboviral disease in the world. Aim: To know about the knowledge and current practice of the emergency physicians and other physicians regarding admission criteria of dengue fever in Kolkata. To preserve the resource and to prevent unnecessary utilization of hospital facilities during dengue epidemics by following up the proper criteria of admission for acute febrile patient suspecting of dengue fever/ dengue hemorrhagic fever/ dengue shock syndrome from the emergency department. Materials and methods: This is a questionnaire-based study and the study was conducted in peerless hospital and b.k roy research centre. The duration of the study was one year (from 1/01/2019- 31/12/2020). Apre validated questionnaire was distributed among the emergency physicians and other general physicians who deal with management of dengue patients and the responses so obtained were analysed. Total 125 participants were present in this study. Result: We found that 5(4.0%) doctors work in Cardiology department, 40(32.0%) doctors work in Emergency medicine department, 6(4.8%) doctors work in Gynecology department, 46(36.8%) doctors work in Medicine department, 8(6.4%) doctors work in Nephrology department, 8(6.4%) doctors work in Neurology department, 8(6.4%) doctors work in Orthopedic department and 4(3.2%) doctors work in Surgery department. Conclusion: However, a knowledge gap has been reported regarding important issues in clinical presentation, treatment, prevention, and control. Practices regarding frequent clinical monitoring were consistent with local and international guide-lines


2020 ◽  
Vol 40 (2) ◽  
pp. 93-99
Author(s):  
Saheli Misra Chatterjee ◽  
Suman Mondal ◽  
Kaushik Mukhopadhyay ◽  
Niloy Kumar Das

Introduction: The disease spectrum of dengue, scrub typhus and typhoid presenting as acute febrile illness is often a diagnostic dilemma to the clinician. The purpose of this study is to compare the clinical features and laboratory parameters of children suffering from typhoid, dengue and scrub typhus and use these parameters in early identification of scrub typhus before conclusion is made from serological diagnosis. Methods: A retrospective observational analytical study was conducted among children presenting with acute febrile illness in a tertiary care level hospital. Over the period of one year 113 cases were identified of which 39 were dengue, 44 were typhoid and 30 were scrub typhus. Results: The mean age of the children was 7.45 ± 2.98 years, median was eight with an interquartile range of six to ten years. The male to female ratio was 1.3:1. Symptoms of vomiting (61.54%), headache (46.15%) and hepatomegaly (47.37%) were significantly higher among children with dengue fever. A significantly higher number of children with scrub typhus fever had temperature above 40°C. The incidence of low haemoglobin, raised C reactive protein, raised ALT and low albumin levels were significantly higher in them. Children with acute febrile illness having temperature > 40°C, absolute neutrophil/lymphocyte ratio > 2 early in the illness were more likely to suffer from scrub typhus with relative probability ratio (RPR) of 25.68 and 10.57 respectively (p < 0.001). Children with WBC < 5000/mm3 were more likely to be suffering from dengue with RPR of 10.60 (p < 0.001). Conclusion: Children with acute febrile illness with temperature > 40°C and absolute neutrophil/lymphocyte ratio > 2 early in the illness were more likely to be suffering from scrub typhus.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Anish Laul ◽  
Poonam Laul ◽  
Vamsi Merugumala ◽  
Ravi Pathak ◽  
Urvashi Miglani ◽  
...  

Introduction.Dengue fever is an arboviral disease, which is transmitted by mosquito vector and presents as varied clinical spectrum of dengue fever (DF), dengue hemorrhagic fever (DHF), dengue shock syndrome (DSS), and expanded dengue syndrome (EDS) with atypical presentations, thus posing a diagnostic dilemma. Unless we are aware of these presentations, diagnosis as well as early initiation of treatment becomes difficult. We studied the various clinical presentations of dengue infection during an outbreak of disease in 2015.Materials and Methods. A total of 115 confirmed cases of dengue infection from Department of Medicine of Deen Dayal Upadhyay Hospital, New Delhi, were enrolled in this observational study.Results.The common signs and symptoms of dengue infection were fever, headache, body ache, backache, retro-orbital pain, bleeding manifestations, and rash in 100%, 87%, 86%, 58%, 41%, 21%, and 21%, respectively. Nonspecific or warning signs and symptoms included vomiting, weakness, abdominal pain, breathlessness, vertigo, sweating, and syncope. Other possible signs and symptoms of coinfections, comorbidities, or complications included diarrhea, sore throat, and neurological manifestations. There were seven patients with coinfections and four with comorbidities. The final diagnosis of these patients was DF (73%), DHF (16.5%), DSS (1.7%), and EDS (4.3%). Among EDS patients, the atypical presentations included encephalopathy, lateral rectus nerve palsy, acalculous cholecystitis, and myocarditis. Four patients required ICU care and there was no death in this study.Conclusion. Knowledge of atypical presentations is a must for early diagnosis and timely intervention to prevent life-threatening complications.


2022 ◽  
Vol 8 (4) ◽  
pp. 243-247
Author(s):  
Narinder Singh ◽  
Ajeet Pal Singh ◽  
Amar Pal Singh

Dengue fever is a mosquito-borne viral illness that is quickly spreading over the globe, with significant death and morbidity rates. Dengue fever is an acute viral infection transmitted by Aedes mosquitos and caused by an RNA virus from the Flaviviridae family. The symptoms might vary from asymptomatic fever to life-threatening complications including hemorrhagic fever and shock. Although dengue virus infections are normally self-limiting, the disease has become a public health concern in tropical and subtropical countries. Dengue fever is a major public health concern owing to its rapid worldwide spread, and its burdens are now unmet due to a lack of accurate therapy and a simple diagnostic approach for the early stages of illness.


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