ANTI HBS TITRE;

Introduction: The doctors and paramedical staff are at high risk of developingHepatitis B, infection. Hepatitis B vaccine is mandatory for medical students prior to admissionin medical colleges. After completion of vaccination determination of anti HBS is not in practice.All over the world some people remain non responders and don’t develop adequate antibodytitre essential for protection against hepatitis B virus. This study is therefore designed to estimatethe anti HBs titre among the medical students, who have completed three doses of hepatitisB vaccine. Objectives: To determine the serum anti HBs antibodies among the outgoing finalyear MBBS students who have received complete 03 doses of hepatitis B vaccine. StudyDesign: Descriptive cross sectional study. Place and Duration: This study was conductedfrom November 2010 to December 2015 at Biochemistry department Punjab Medical College incollaboration with Nawaz Medicare Hospital Faisalabad. Material and Methods: Two hundredand fifty nine female medical (MBBS) students from outgoing classes during the period ofNovember 2010 to December 2015 were enrolled in this study. All subjects were at the ageof 22-24 years at the time of sampling. Each received 03 doses of injection Engerix B, 10mcg/0.5ml each in a schedule of 0, 01, 06 months since the last 05 years. The blood sampleswere allowed to clot and serum was separated. The anti HBs and HBsAg were determined by3rd generation ELISA method. Results: A total 259 female medical students from outgoing finalyear MBBS classes were enrolled in this study. Among these subjects 48 (18.5%) had serumanti HBs levels < 10 IU/L, 77 subjects (29.7%) have levels 10-20 IU/L, 116 subjects (44.8 %)have serum levels 21-100 IU/L, while 18 subjects (10%) have > 100 IU/L serum anti HBs levels.Conclusion: The incidence of non responders and poor responders is higher among thevaccinees in this study as compared to foreign studies after five years of Hepatitis B vaccination.

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Decrease in Anti-HBs Antibodies over Time in Medical Students and Healthcare Workers after Hepatitis B Vaccination

BioMed Research International ◽

10.1155/2017/1327492 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 5

Author(s):

H. V. Sahana ◽

N. Sarala ◽

S. R. Prasad

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Healthcare Workers ◽

Healthcare Professionals ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Occupational Hazards ◽

Cross Sectional ◽

B Virus ◽

Antibody Titres

Background. Hepatitis B is one of the most important occupational hazards among healthcare workers (HCWs). This study aimed to measure the anti-HBs titres among the medical students and HCWs vaccinated against hepatitis B virus and to determine the association between anti-HBs levels and time since vaccination. Materials and Methods. In this cross-sectional study, medical students and healthcare workers who had received all three doses of hepatitis B vaccination and completed at least six months after vaccination since the last dose were included. 3 ml blood was collected from subjects (n=340) and anti-HBs titre was estimated using ELISA. Results. A total of 340/400 subjects were aged between 18 and 60 years; 204 were females and 136 males. The median and interquartile range for time since vaccination were 5 and 5 years, respectively. Duration since vaccination was ≤5 years in 223 (65.5%), 6–10 years in 84 (24.7%), and >10 years in 33 (9.70%); among them, antibody titres were >10 mIU/ml in 94.1%, 79.7%, and 72.7% subjects, respectively. There was significant decline in antibody titres as duration of postvaccination increased. Conclusion. The proportion of subjects who were unprotected after 5 and 10 years after vaccination were 20% and 27%, respectively. The need for a booster dose can be made mandatory at least for healthcare professionals.

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Hepatitis B vaccine adherence among homeless people

Rev Rene ◽

10.15253/2175-6783.20212260690 ◽

2021 ◽

Vol 22 ◽

pp. e60690

Author(s):

Vanessa Moura Carvalho de Oliveira ◽

Marli Teresinha Gimeniz Galvão ◽

Rômulo Veloso Nunes ◽

Matheus Sousa Marques Carvalho ◽

Cecília Natielly da Silva Gomes ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Surface Antigen ◽

Homeless People ◽

Cross Sectional Study ◽

Hepatitis B Vaccine ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Virus Surface ◽

B Virus

Objective: to estimate the adherence to hepatitis B vaccine in homeless people. Methods: a cross-sectional study with 90 homeless people, with the collection of 5 ml of blood for the detection of antibody against the surface antigen of the hepatitis B virus. Results: of the total, 89 (98.9%) were vaccinated with the first dose; of these, 45 (50.7%) had antibodies against hepatitis B virus surface antigen lower than 10 IU/L; 25 (53.3%) received the second dose of hepatitis B vaccine, and nine (45.8%) participants received the third dose of vaccine. Individuals who were related to both genders were more likely to adhere to the full hepatitis B vaccine schedule. Conclusion: the low adherence to hepatitis B vaccination and the small number of participants with antibodies that confer immunity against this infection were evidenced.

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Knowledge about blood-borne pathogens and the prevalence of needle stick injuries among medical students in Serbia

Slovenian Journal of Public Health ◽

10.1515/sjph-2017-0024 ◽

2017 ◽

Vol 56 (3) ◽

pp. 179-184 ◽

Cited By ~ 2

Author(s):

Vuk Marusic ◽

Ljiljana Markovic-Denic ◽

Olivera Djuric ◽

Dragana Protic ◽

Emilija Dubljanin-Raspopovic

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Disease Transmission ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Needle Stick ◽

Sharp Object ◽

Needle Stick Injuries ◽

Needle Sticks

AbstractIntroductionMedical students are mainly exposed to needle stick and sharp object injuries in the course of their clinical activities during studying. They are at high risk due to their undeveloped skills, restricted clinical experience, lack of knowledge and risk perception. The objectives of this study were to determine the prevalence of needle stick injuries of the fourth and final year medical students, and to estimate their knowledge about blood-borne pathogens disease transmission and standard precautions.MethodsThis cross-sectional study was conducted at the Faculty of Medicine, in February 2014. The students were invited to self-administer a questionnaire of 26 closed questions prepared for this study.ResultsThe questionnaire was filled in and returned by 637 students. The prevalence of needle sticks and sharp object injuries was 29.5%. Needle stick injuries were the most common type of accidents, more frequent among the fourth compared to the sixth year students (p=0.002). The majority of accidents occurred in patient rooms (53%) and the emergency department (15%). 54% of participants reported an accident to the responsible person. Students without accidents had a significantly better perception of risk (3.79 vs. 3.35; p<0.05). Out of the total participating students, only 16.6% (106/637) received all three doses of Hepatitis B vaccination, while 16.2% were partially vaccinated.ConclusionsThere is a need for additional theoretical and practical education of our students on blood exposure via accidents, raising the awareness of the necessity of hepatitis B vaccination, and introducing the unique/comprehensive procedure for accident reporting for students and healthcare workers in the entire country.

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Hepatitis B virus seroprevalence among Malawian medical students: A cross-sectional study

Malawi Medical Journal ◽

10.4314/mmj.v29i1.6 ◽

2017 ◽

Vol 29 (1) ◽

pp. 29 ◽

Cited By ~ 1

Author(s):

Froid Chipetah ◽

Aaron Chirambo ◽

Ednas Billiat ◽

Isaac Thom Shawa

Keyword(s):

Hepatitis B Virus ◽

Medical Students ◽

Hepatitis B ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

B Virus

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The Association of N-Glycan and Alpha Fetal Protein in Hepatitis B Associated Hepatic Disease

10.21203/rs.3.rs-124177/v1 ◽

2020 ◽

Author(s):

Li Guo ◽

Lijun Wan ◽

Youwen Hu ◽

Bo He ◽

Moran Zhang ◽

...

Keyword(s):

Hepatitis B ◽

Hematological Parameters ◽

Serum Levels ◽

Cross Sectional Study ◽

Hepatic Disease ◽

Cellular Functions ◽

Cross Sectional ◽

Hepatic Diseases ◽

B Virus ◽

Serum Alpha Fetoprotein

Abstract Objective: Chronic hepatic disease caused by hepatitis B virus (HBV) is a serious threat to health in worldwide. There is evidence that the change of N-glycan is involved in the mechanism of hepatic fibrosis, liver cirrhosis (LC) and hepatocellular carcinoma (HCC) in patients with hepatitis B. The level of serum alpha-fetoprotein (AFP) is elevated in many patients with hepatitis B infection. AFP is not only a fetal carrier protein and tumor marker, but also participates in the regulation of a variety of important cellular functions, such as cell growth, differentiation, apoptosis, angiogenesis and immune regulation. However, the mechanism between AFP and N-glycan is not clear. The study investigated the association of N-glycan and AFP in Hepatitis B associated hepatic disease.Patients and Methods: Sixty patients with Hepatitis B associated hepatic diseases and twenty healthy individuals were selected in this study. Serum AFP, N-glycan, hematological parameters, and clinical data were assessed in this cohort. The Spearman rank method was used to evaluate the associations among them. The study was designed as a retrospective cross-sectional study. Results：Serum levels of N-glycan and AFP were signiﬁcantly higher in Patients with hepatic disease compared with the controls; levels of both were elevated with development of the disease. In patients with hepatic disease, N-glycan was positively correlated with AFP, Age, AST, GGT, PT, CA125, while negatively correlated with ALB, CHE, RBC (P < 0.05 for all). AFP was positively correlated with HBV DNA, TBIL, DBIL, AST, ALT, ALP, GGT (P < 0.05 for all), while negatively correlated with ALB and CHE in hepatic disease patients (P < 0.05 for both). In addition, there was a trend of increasing N-glycan with elevated AFP level in the combined hepatic disease group. In LC, the level of N-glycan in the decompensatory was signiﬁcant higher than in the control (P = 0.007), and AFP level in the compensatory increased than the controls (P = 0.003). In HCC, levels of both N-glycan and AFP in the compensatory and decompensatory groups elevated than those in the control (P < 0.001 and P = 0.004 for N-glycan and P < 0.001 for both in AFP, respectively).Conclusion: Our data suggest that high AFP levels in Hepatitis B related hepatic disease are closely related to the development of liver disease through interaction with N-glycan.

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Awareness of Hepatitis B Vaccination in Rural Area: A Survey

Journal of Current and Advance Medical Research ◽

10.3329/jcamr.v1i1.19558 ◽

2014 ◽

Vol 1 (1) ◽

pp. 3-7

Author(s):

Kamrun Nahar Sweety ◽

Shamim Akther Mimi

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Rural Area ◽

Cross Sectional Study ◽

Hbv Infection ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Hbv Vaccination ◽

B Virus ◽

Almost All

Background: The awareness regarding Hepatitis B vaccination is necessary in the general population of Bangladesh.Objective: This study was carried out to determine the level of knowledge and the vaccination coverage of hepatitis B virus in rural population.Methodology: This cross sectional study was conducted at Bangladesh Institute of Administration and Management (BIAM), Dhaka, Bangladesh from February 2011 to April 2011. Sirajdikhan upazila of Munshiganj District was taken as a study place. All the villagers with an age group of 15 to 55 years were taken as study population. Result: A total number of 30 respondents were recruited of which male (60.0%) is predominant than female (40.0%). The mean age with SD was 23±7.256 years (range 15-53 years). Majority has told about the knowledge regarding the sequel of hepatitis B virus infection (33.3%). Almost all respondents (96.7%) are unknown about the treatment of HBV infection. Majority (76.7%) are unknown regarding taking HBV vaccination. Nobody has given positive answer in response to take vaccine. Conclusion: In conclusion information and knowledge regarding HBV infection and vaccination is very poor in the rural area of Bangladesh.DOI: http://dx.doi.org/10.3329/jcamr.v1i1.19558J Curr Adv Med Res 2014;1(1):3-7

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Study to Assess the Status of Hepatitis B Vaccination and Factors Affecting Antibody Titers Level for Hepatitis B to Various Health Care Workers and Medical Students in Tertiary Healthcare Setup in Himachal Pradesh

International Journal of Research and Review ◽

10.52403/ijrr.20210933 ◽

2021 ◽

Vol 8 (9) ◽

pp. 242-246

Author(s):

Aditya Rana ◽

Subhash Chand Jaryal ◽

Anuradha Sood

Keyword(s):

Medical Student ◽

Medical Students ◽

Hepatitis B ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Factors Affecting ◽

Hbv Vaccination ◽

Tertiary Healthcare ◽

Antibody Titers

Background: Hepatitis B(HBV) is one of the most important occupational hazards among the medical student and healthcare workers(HCW's) due to risk of exposure to infected bodily fluids and blood. This study aimed to assess status of HBV vaccination and factors affecting anti-HBs titres levels for HBV in HCW and medical students. Material and Method: It was a prospective, descriptive and cross sectional study done at the Department of Microbiology, DRPGMC Kangra at Tanda(H.P). Randomly 215 HCW’s and medical students were taken in the study who fulfilled the inclusion criteria. Results: Total of 215 subjects were included in the study. Males were 89 and females were 126. 182 subjects were vaccinated and 33 were unvaccinated for hepatitis B. Out of 182 vaccinated 137 were completely vaccinated. Significant correlation was seen with decrease in antibody titers with gender, duration of vaccination and smoking. Conclusion: Vaccination should be mandatory for every HCW and medical student entering the health institutions. The factors affecting the antibody titers must be evaluated and antibody titers must be reviewed from time to time. The need for a booster dose can be made mandatory at least for healthcare professionals. Keywords: Hepatitis B virus, Vaccination, Antibody titers, HCW.

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Vaccination Status and Awareness of Hepatitis B among Undergraduate Medical Students of Two Medical Colleges in Bangladesh

Medicine Today ◽

10.3329/medtoday.v28i1.30968 ◽

2017 ◽

Vol 28 (1) ◽

pp. 27-29

Author(s):

Maj Shahida Akhter ◽

ASM Rizwan ◽

Md Wahiduzzaman

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Health Care Professionals ◽

Cross Sectional Study ◽

Vaccination Status ◽

First Year ◽

Undergraduate Medical Students ◽

Cross Sectional ◽

Medical College ◽

Female Data

Hepatitis B is a pandemic disease affecting millions of people. Vaccination and preventive knowledge is crucial for all especially health care professionals. To evaluate the vaccination status and level of knowledge and awareness regarding hepatitis B among undergraduate medical students ranging from first to fifth year. This is a cross-sectional study which was conducted in Dhaka Medical College, Dhaka during July 2012 to July 2015. Total 217 students participated in the study (36.4% male and 63.6% female). Data was collected using a structured questionnaire. Statistical analysis was done using SPSS version 20. Most of the responders were female (63.6%) and from first year (31.3%). Only 41.4% were vaccinated properly and another 9.2% received incomplete doses. Those who had more knowledge regarding hepatitis B were practicing more preventive measures. The present study showed that there is much lack of knowledge and awareness about hepatitis B among medical college students that make them vulnerable to acquire the disease. Moreover, the vaccination status is also not satisfactory which should be taken seriously.Medicine Today 2016 Vol.28(1): 27-29

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Assessment of knowledge, attitude, and practice regarding hepatitis B among medical students in a private medical college in Kochi

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20191552 ◽

2019 ◽

Vol 6 (5) ◽

pp. 1938

Author(s):

Arun Jacob ◽

Teena Mary Joy ◽

Sreelakshmi Mohandas ◽

Harsha Lais ◽

Nimitha Paul

Keyword(s):

Hepatitis B Virus ◽

Medical Students ◽

Hepatitis B ◽

Sexual Transmission ◽

Cross Sectional Study ◽

Hepatitis B Infection ◽

Cross Sectional ◽

B Virus ◽

Knowledge And Attitude ◽

The Right

Background: Hepatitis B virus is transmitted by body fluids, such as blood and serum. Sexual transmission, vertical transmission, and unsafe injections, including intravenous drug use, are the most common routes of infection for Hepatitis B infection. Medical students have a very important role in preventing the disease by improving the disease knowledge among themselves and the patients they will eventually treat.Methods: A cross sectional study was conducted to assess the KAP among medical students of the first three academic years regarding hepatitis B virus infection. The sample size was 222 students. Data were collected from 230 students using a semi structured questionnaire and analyzed using SPSS v20.Results: Among 230 medical students, 79.1% students had good knowledge about hepatitis B whereas 84.3% of the respondents had the right attitude towards hepatitis B. The practice component was low with only 44.8% of the respondents having correct practice regarding hepatitis B infection.Conclusions: Although the knowledge and attitude regarding hepatitis B infection is high, the practice levels are low indicating the need to encourage proper practices among the medical students.

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Hepatitis B Awareness among Medical Students and Their Vaccination Status at Syrian Private University

Hepatitis Research and Treatment ◽

10.1155/2014/131920 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Nazir Ibrahim ◽

Amr Idris

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Private University ◽

Cross Sectional Study ◽

Vaccination Status ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Hbv Vaccine ◽

Care Workers ◽

The Status

Background. Hepatitis B virus (HBV) is a potentially life-threating infection and a well-recognized occupational hazard for health-care workers including medical students. Methods. A cross-sectional study was conducted at Syrian Private University (SPU), Faculty of Medicine, to assess the knowledge and awareness about hepatitis B, the status of hepatitis B vaccination, and the reasons for not getting vaccinated among the first- and the fifth-year medical students. Results. The present study demonstrates surprising results and raises issues about the high number of medical students that are not vaccinated or not sure about their vaccination status, which puts them at a higher risk of being infected in the future. Another important issue is the medical students’ overall knowledge about this life-threating infection. The students have not been totally educated about the gravity of the situation which requires the need of further HBV education. It is highly recommended that SPU provides the HBV vaccine to all nonvaccinated students attending the faculty of medicine at no cost to encourage them to take the HBV vaccine and to reform some of its educational curriculum to effectively limit the hazardous effects of this disease and elaborate on the serious health consequences of HBV.

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