Study to Assess the Status of Hepatitis B Vaccination and Factors Affecting Antibody Titers Level for Hepatitis B to Various Health Care Workers and Medical Students in Tertiary Healthcare Setup in Himachal Pradesh

Background: Hepatitis B(HBV) is one of the most important occupational hazards among the medical student and healthcare workers(HCW's) due to risk of exposure to infected bodily fluids and blood. This study aimed to assess status of HBV vaccination and factors affecting anti-HBs titres levels for HBV in HCW and medical students. Material and Method: It was a prospective, descriptive and cross sectional study done at the Department of Microbiology, DRPGMC Kangra at Tanda(H.P). Randomly 215 HCW’s and medical students were taken in the study who fulfilled the inclusion criteria. Results: Total of 215 subjects were included in the study. Males were 89 and females were 126. 182 subjects were vaccinated and 33 were unvaccinated for hepatitis B. Out of 182 vaccinated 137 were completely vaccinated. Significant correlation was seen with decrease in antibody titers with gender, duration of vaccination and smoking. Conclusion: Vaccination should be mandatory for every HCW and medical student entering the health institutions. The factors affecting the antibody titers must be evaluated and antibody titers must be reviewed from time to time. The need for a booster dose can be made mandatory at least for healthcare professionals. Keywords: Hepatitis B virus, Vaccination, Antibody titers, HCW.

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Knowledge about blood-borne pathogens and the prevalence of needle stick injuries among medical students in Serbia

Slovenian Journal of Public Health ◽

10.1515/sjph-2017-0024 ◽

2017 ◽

Vol 56 (3) ◽

pp. 179-184 ◽

Cited By ~ 2

Author(s):

Vuk Marusic ◽

Ljiljana Markovic-Denic ◽

Olivera Djuric ◽

Dragana Protic ◽

Emilija Dubljanin-Raspopovic

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Disease Transmission ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Needle Stick ◽

Sharp Object ◽

Needle Stick Injuries ◽

Needle Sticks

AbstractIntroductionMedical students are mainly exposed to needle stick and sharp object injuries in the course of their clinical activities during studying. They are at high risk due to their undeveloped skills, restricted clinical experience, lack of knowledge and risk perception. The objectives of this study were to determine the prevalence of needle stick injuries of the fourth and final year medical students, and to estimate their knowledge about blood-borne pathogens disease transmission and standard precautions.MethodsThis cross-sectional study was conducted at the Faculty of Medicine, in February 2014. The students were invited to self-administer a questionnaire of 26 closed questions prepared for this study.ResultsThe questionnaire was filled in and returned by 637 students. The prevalence of needle sticks and sharp object injuries was 29.5%. Needle stick injuries were the most common type of accidents, more frequent among the fourth compared to the sixth year students (p=0.002). The majority of accidents occurred in patient rooms (53%) and the emergency department (15%). 54% of participants reported an accident to the responsible person. Students without accidents had a significantly better perception of risk (3.79 vs. 3.35; p<0.05). Out of the total participating students, only 16.6% (106/637) received all three doses of Hepatitis B vaccination, while 16.2% were partially vaccinated.ConclusionsThere is a need for additional theoretical and practical education of our students on blood exposure via accidents, raising the awareness of the necessity of hepatitis B vaccination, and introducing the unique/comprehensive procedure for accident reporting for students and healthcare workers in the entire country.

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A STUDY TO ASSESS THE SEROPREVALENCE OF HEPATITIS B AND ANTI HBS ANTIBODY LEVELS AMONGST HEALTH CARE WORKERS AND MEDICAL STUDENTS.

10.36106/ijsr/8002609 ◽

2021 ◽

pp. 84-85

Author(s):

Aditya Rana ◽

Anuradha Sood

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Healthcare Workers ◽

Base Material ◽

Hepatitis B Vaccination ◽

Continuous Exposure ◽

Cross Sectional ◽

Antibody Titres ◽

Antibody Titers ◽

Antibody Levels

Background: Hepatitis B(HBV) is a blood borne virus and it is one of the most important occupational hazards among healthcare workers (HCWs) & Medical students. This study aimed to measure the anti-HBs titres and to assess the seroprevalence of Hepatitis B in HCW and medical students. It was a prospective,descriptive and cross sectional hospital base Material and method: d study. Medical students and healthcare workers who had received all three doses of hepatitis B vaccination were included in the study. A total of 200 subjects , aged between 18 and Result: 62 years were taken. 182 were vaccinated and 18 were unvaccinated. 85 were males and 115 females. Seroprevalence of Hepatitis B was nil. Antibody titres were >100mIU/ml in 51.6% , 10-100mIU/ml in 16.4% & <10 mIU/ml in 31.8% respectively.Negative correlation of decreasing antibiotic titer and age was seen. HCW and medical students are at hi Conclusion: gher risk due to their continuous exposure to blood products. Vaccination should be compulsory to the HCW and medical workers in the institution as Hepatitis B is a preventable disease. Monitoring of antibody titers should be done from time to time to see waning off antibody titers after vaccination

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Knowledge, Preference, and Willingness to Pay for Hepatitis B Vaccination Services among Woman of Reproductive Age in Vietnam

BioMed Research International ◽

10.1155/2019/9154918 ◽

2019 ◽

Vol 2019 ◽

pp. 1-7

Author(s):

Anh Tuan Le Nguyen ◽

Xuan Thanh Thi Le ◽

Toan Thanh Thi Do ◽

Cuong Tat Nguyen ◽

Long Hoang Nguyen ◽

...

Keyword(s):

Hepatitis B ◽

Willingness To Pay ◽

Cross Sectional Study ◽

Reproductive Age ◽

Hepatitis B Vaccination ◽

Critical Approach ◽

Cross Sectional ◽

Hbv Vaccine ◽

Number Of Children ◽

Hbv Vaccination

Background. Hepatitis B virus (HBV) vaccine is a critical approach to prevent HBV transmission from mother to child. However, despite high HBV prevalence, evidence about the preference of women of productive age for HBV vaccine in Vietnam was constrained. This study aims to explore the preference and willingness to pay (WTP) for the HBV vaccine in Vietnamese women in productive age. Methods. A cross-sectional study was conducted in Hanoi in April 2016. A structured questionnaire was used to collect information about respondents’ socioeconomic status and knowledge about HBV vaccination. A contingent valuation approach was employed to measure the WTP for the HBV vaccine. Logistic and interval regressions were used to determine the associated factors. Results. Among 807 women, 80.8% were willing to have the vaccine injected which had the average price of 108,600 VND (95% CI, 97,580 VND–119,570 VND). Participants not suffering any diseases during pregnancy were more likely to be willing to pay for the HBV vaccine (OR = 3.41, 95% CI = 1.73–6.70). Not having the antenatal examination at central hospitals and working as farmers/workers were positively correlated with willingness to pay for this vaccine, while the number of children of respondents had a negative correlation with WTP. Conclusions. Our sampled women expressed a high willingness to pay for the vaccine. The price people were willing to pay for the vaccine, however, is equal to half of the actual price. These findings implied needs for better targeted public education interventions about HBV and the involvement of local medical staffs and the media in providing information. Efforts to reduce the price of the vaccine should also be warranted for scaling-up the coverage of this vaccine.

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Awareness of Hepatitis B Vaccination in Rural Area: A Survey

Journal of Current and Advance Medical Research ◽

10.3329/jcamr.v1i1.19558 ◽

2014 ◽

Vol 1 (1) ◽

pp. 3-7

Author(s):

Kamrun Nahar Sweety ◽

Shamim Akther Mimi

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Rural Area ◽

Cross Sectional Study ◽

Hbv Infection ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Hbv Vaccination ◽

B Virus ◽

Almost All

Background: The awareness regarding Hepatitis B vaccination is necessary in the general population of Bangladesh.Objective: This study was carried out to determine the level of knowledge and the vaccination coverage of hepatitis B virus in rural population.Methodology: This cross sectional study was conducted at Bangladesh Institute of Administration and Management (BIAM), Dhaka, Bangladesh from February 2011 to April 2011. Sirajdikhan upazila of Munshiganj District was taken as a study place. All the villagers with an age group of 15 to 55 years were taken as study population. Result: A total number of 30 respondents were recruited of which male (60.0%) is predominant than female (40.0%). The mean age with SD was 23±7.256 years (range 15-53 years). Majority has told about the knowledge regarding the sequel of hepatitis B virus infection (33.3%). Almost all respondents (96.7%) are unknown about the treatment of HBV infection. Majority (76.7%) are unknown regarding taking HBV vaccination. Nobody has given positive answer in response to take vaccine. Conclusion: In conclusion information and knowledge regarding HBV infection and vaccination is very poor in the rural area of Bangladesh.DOI: http://dx.doi.org/10.3329/jcamr.v1i1.19558J Curr Adv Med Res 2014;1(1):3-7

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Pregnant women’s hepatitis B vaccination coverage in Nigeria: a national pilot cross-sectional study

Therapeutic Advances in Vaccines and Immunotherapy ◽

10.1177/25151355211032595 ◽

2021 ◽

Vol 9 ◽

pp. 251513552110325

Author(s):

George Uchenna Eleje ◽

Godwin Otuodichinma Akaba ◽

Ikechukwu Innocent Mbachu ◽

Ayyuba Rabiu ◽

Olabisi Morebise Loto ◽

...

Keyword(s):

Logistic Regression ◽

Hepatitis B ◽

Pregnant Women ◽

Vaccination Coverage ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Sectional Study ◽

Cross Sectional ◽

Factors Affecting ◽

Level Of Education

Objective: To determine the hepatitis B vaccination coverage, full-dose (⩾3) coverage and the associated factors affecting uptake among pregnant women. Methods: This was a cross-sectional study among pregnant women attending antenatal care in six tertiary hospitals across all the geopolitical zones of Nigeria. Pregnant women who consented to the study completed screening questions about their hepatitis B vaccination status and coverage. The main outcome measures were hepatitis B vaccination coverage rate, dose, and factors affecting uptake. Bivariate analysis was performed by the chi-square test and conditional logistic regression analysis was used to determine variables associated with uptake of the vaccination. Odds ratios (ORs) and adjusted odds ratios (aORs) were calculated and statistical significance was accepted when p-value was < 0.05. Results: Of 159 pregnant women who completed the interview questions, 21 [13.2%, 95% confidence interval (CI) 7.9–18.5%] were vaccinated for hepatitis B for one to three doses. The numbers of doses received were: three doses (8/159, 5.0%), two doses (5/159, 3.1%), and one dose (8/159, 5.0%). The reasons for non-uptake of vaccination included: lack of awareness of the vaccine 83/138 (60.1%), inadequate access to vaccine 11/138 (8.0%), and positivity to hepatitis B virus 10/138 (7.2%). The uptake of hepatitis B vaccination was significantly affected by the level of education (OR 0.284, 95% CI 0.08–1.01, p = 0.041), but in multivariable logistic regression, adjusted for confounders, the association between hepatitis B vaccination and participants’ level of education (aOR 3.09; 95% CI 0.95–10.16; p = 0.061) did not remain significant. Conclusions: In Nigeria, the national hepatitis B vaccination coverage among pregnant women appears poor, with the full-dose coverage even poorer. The level of education was not positively associated with uptake of hepatitis B vaccination, while lack of awareness of the vaccine was the commonest reason for non-uptake. Funding: TETFund National Research Fund 2019 (grant number TETFund/DR&D/CE/NRF/STI/33).

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Decrease in Anti-HBs Antibodies over Time in Medical Students and Healthcare Workers after Hepatitis B Vaccination

BioMed Research International ◽

10.1155/2017/1327492 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 5

Author(s):

H. V. Sahana ◽

N. Sarala ◽

S. R. Prasad

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Healthcare Workers ◽

Healthcare Professionals ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Occupational Hazards ◽

Cross Sectional ◽

B Virus ◽

Antibody Titres

Background. Hepatitis B is one of the most important occupational hazards among healthcare workers (HCWs). This study aimed to measure the anti-HBs titres among the medical students and HCWs vaccinated against hepatitis B virus and to determine the association between anti-HBs levels and time since vaccination. Materials and Methods. In this cross-sectional study, medical students and healthcare workers who had received all three doses of hepatitis B vaccination and completed at least six months after vaccination since the last dose were included. 3 ml blood was collected from subjects (n=340) and anti-HBs titre was estimated using ELISA. Results. A total of 340/400 subjects were aged between 18 and 60 years; 204 were females and 136 males. The median and interquartile range for time since vaccination were 5 and 5 years, respectively. Duration since vaccination was ≤5 years in 223 (65.5%), 6–10 years in 84 (24.7%), and >10 years in 33 (9.70%); among them, antibody titres were >10 mIU/ml in 94.1%, 79.7%, and 72.7% subjects, respectively. There was significant decline in antibody titres as duration of postvaccination increased. Conclusion. The proportion of subjects who were unprotected after 5 and 10 years after vaccination were 20% and 27%, respectively. The need for a booster dose can be made mandatory at least for healthcare professionals.

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Knowledge, Attitude and Awareness of Hepatitis B Vaccination in Patients Visiting Jinnah Postgraduate Medical Center, Karachi

Liaquat National Journal of Primary Care ◽

10.37184/lnjpc.2707-3521.1.3 ◽

2019 ◽

Keyword(s):

Hepatitis B ◽

Medical Center ◽

Data Entry ◽

Sampling Technique ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Hbv Vaccine ◽

Hbv Vaccination ◽

Increased Risk

Background: Hepatitis B Virus (HBV) is a major health issue of the developing world, especially in Pakistan. Chronic Hepatitis B leads to an increased risk of liver cirrhosis and hepatocellular carcinoma and is a massive burden on the total health expenditure of the nation. However, in our country people lack knowledge regarding the HBV vaccine and its availability and have various other reasons for not getting vaccinated. The purpose of this research was to observe the attitude of patients visiting Jinnah Postgraduate Medical Center towards Hepatitis B vaccination as well as the reasons put forward by those who choose not to get vaccinated. Objectives: The aim of this study was to evaluate the knowledge, attitudes and awareness regarding HBV vaccination in patients visiting Jinnah Postgraduate Medical Center. Methodology: This is a cross sectional study that was conducted among patients who visited Jinnah Postgraduate Medical Center. 300 participants were included. The data collection method was a face-to-face interview. Non-probability convenience sampling technique was used to recruit patients. We used a self-structured, close-ended questionnaire based on the Urdu language consisting of a total of 40 questions. Prior written consent was taken. Data entry and data analysis were done by using SPSS Version 20. Results: Out of 300 participants, 63.67% of respondents had acquired matriculation or higher education while the rest were either just primary pass or illiterate. 216(72%) of the participants were aware that HBV is highly prevalent in Pakistan. 135(45%) considered alcohol and smoking as a cause of HBV. Only 43(14.3%) participants had knowledge regarding the standard dosing regimen of the vaccine. Participants had awareness about prevention. 250 (83.3%) agreed that Hepatitis B vaccination is an effective method of prevention of Hepatitis B, while 59(19.6%) thought that the vaccine itself can cause Hepatitis infection. 190(63.3%) identified cost as a barrier for vaccination. Conclusion: People in Pakistan don’t have adequate knowledge about the mode of transmission of hepatitis, but they have good knowledge about preventive methods. The prevalent attitude is to not get vaccinated due to various reasons. Hence it is very important to spread awareness among people about HBV vaccination.

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ANTI HBS TITRE;

The Professional Medical Journal ◽

10.29309/tpmj/2017.24.08.1008 ◽

2017 ◽

Vol 24 (08) ◽

pp. 1167-1169

Author(s):

Nahdia Ashraf ◽

Muhammad Usman Hussain ◽

Iqra Qamar ◽

Muhammad Ashraf

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Serum Levels ◽

Cross Sectional Study ◽

Hepatitis B Vaccine ◽

Hepatitis B Vaccination ◽

Poor Responders ◽

Cross Sectional ◽

Medical College ◽

B Virus

Introduction: The doctors and paramedical staff are at high risk of developingHepatitis B, infection. Hepatitis B vaccine is mandatory for medical students prior to admissionin medical colleges. After completion of vaccination determination of anti HBS is not in practice.All over the world some people remain non responders and don’t develop adequate antibodytitre essential for protection against hepatitis B virus. This study is therefore designed to estimatethe anti HBs titre among the medical students, who have completed three doses of hepatitisB vaccine. Objectives: To determine the serum anti HBs antibodies among the outgoing finalyear MBBS students who have received complete 03 doses of hepatitis B vaccine. StudyDesign: Descriptive cross sectional study. Place and Duration: This study was conductedfrom November 2010 to December 2015 at Biochemistry department Punjab Medical College incollaboration with Nawaz Medicare Hospital Faisalabad. Material and Methods: Two hundredand fifty nine female medical (MBBS) students from outgoing classes during the period ofNovember 2010 to December 2015 were enrolled in this study. All subjects were at the ageof 22-24 years at the time of sampling. Each received 03 doses of injection Engerix B, 10mcg/0.5ml each in a schedule of 0, 01, 06 months since the last 05 years. The blood sampleswere allowed to clot and serum was separated. The anti HBs and HBsAg were determined by3rd generation ELISA method. Results: A total 259 female medical students from outgoing finalyear MBBS classes were enrolled in this study. Among these subjects 48 (18.5%) had serumanti HBs levels < 10 IU/L, 77 subjects (29.7%) have levels 10-20 IU/L, 116 subjects (44.8 %)have serum levels 21-100 IU/L, while 18 subjects (10%) have > 100 IU/L serum anti HBs levels.Conclusion: The incidence of non responders and poor responders is higher among thevaccinees in this study as compared to foreign studies after five years of Hepatitis B vaccination.

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Hepatitis B Awareness among Medical Students and Their Vaccination Status at Syrian Private University

Hepatitis Research and Treatment ◽

10.1155/2014/131920 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

Nazir Ibrahim ◽

Amr Idris

Keyword(s):

Medical Students ◽

Hepatitis B ◽

Private University ◽

Cross Sectional Study ◽

Vaccination Status ◽

Hepatitis B Vaccination ◽

Cross Sectional ◽

Hbv Vaccine ◽

Care Workers ◽

The Status

Background. Hepatitis B virus (HBV) is a potentially life-threating infection and a well-recognized occupational hazard for health-care workers including medical students. Methods. A cross-sectional study was conducted at Syrian Private University (SPU), Faculty of Medicine, to assess the knowledge and awareness about hepatitis B, the status of hepatitis B vaccination, and the reasons for not getting vaccinated among the first- and the fifth-year medical students. Results. The present study demonstrates surprising results and raises issues about the high number of medical students that are not vaccinated or not sure about their vaccination status, which puts them at a higher risk of being infected in the future. Another important issue is the medical students’ overall knowledge about this life-threating infection. The students have not been totally educated about the gravity of the situation which requires the need of further HBV education. It is highly recommended that SPU provides the HBV vaccine to all nonvaccinated students attending the faculty of medicine at no cost to encourage them to take the HBV vaccine and to reform some of its educational curriculum to effectively limit the hazardous effects of this disease and elaborate on the serious health consequences of HBV.

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Hepatitis B Vaccination in Senegalese Children: Coverage, Timeliness, and Sociodemographic Determinants of Non-Adherence to Immunisation Schedules (ANRS 12356 AmBASS Survey)

Vaccines ◽

10.3390/vaccines9050510 ◽

2021 ◽

Vol 9 (5) ◽

pp. 510

Author(s):

Lauren Périères ◽

Fabienne Marcellin ◽

Gora Lo ◽

Camelia Protopopescu ◽

El Ba ◽

...

Keyword(s):

Hepatitis B ◽

Dose Schedule ◽

World Health Organisation ◽

Sub Saharan Africa ◽

World Health ◽

Hepatitis B Vaccination ◽

Detailed Knowledge ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Hbv Vaccination

Detailed knowledge about hepatitis B virus (HBV) vaccination coverage and timeliness for sub-Saharan Africa is scarce. We used data from a community-based cross-sectional survey conducted in 2018–2019 in the area of Niakhar, Senegal, to estimate coverage, timeliness, and factors associated with non-adherence to the World Health Organisation-recommended vaccination schedules in children born in 2016 (year of the birth dose (BD) introduction in Senegal) and 2017–2018. Vaccination status was assessed from vaccination cards, surveillance data, and healthcare post vaccination records. Among 241 children with available data, for 2016 and 2017–2018, respectively, 31.0% and 66.8% received the BD within 24 h of birth (BD schedule), and 24.3% and 53.7% received the BD plus at least two pentavalent vaccine doses within the recommended timeframes (three-dose schedule). In logistic regression models, home birth, dry season birth, and birth in 2016 were all associated with non-adherence to the recommended BD and three-dose schedules. Living over three kilometres from the nearest healthcare post, being the firstborn, and living in an agriculturally poorer household were only associated with non-adherence to the three-dose schedule. The substantial proportion of children not vaccinated according to recommended schedules highlights the importance of considering vaccination timeliness when evaluating vaccination programme effectiveness. Outreach vaccination activities and incentives to bring children born at home to healthcare facilities within 24 h of birth, must be strengthened to improve timely HBV vaccination.

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