scholarly journals Frequency of helicobacter pylori stool antigen in individuals with dyspeptic symptom

2019 ◽  
Vol 26 (06) ◽  
Author(s):  
Khalid Ahmed Tareen ◽  
Riaz Hussain Awan ◽  
Seema Nayab ◽  
Khadim Hussain Awan ◽  
Faqir Muhammad Awan

Objectives: To evaluate the frequency of H. pylori stool antigen in individuals with dyspepsia. Study Design: Cross sectional study. Setting: Liaquat National Hospital, Karachi. Period: July-2017 to 31st December-2017). Patients and Methods: The individuals with dyspeptic symptoms for ≥3 months durations were included and explored for H. Pylori infection by H. Pylori stool antigen while the result were analyzed and frequencies and percentages were calculated. Results: The mean ± SD for overall population was 36.29±8.57 years while the frequency of H. pylori was recorded as 38.57% (54/140) patients respectively. Conclusion: H. pylori infection usually observed in dyspeptic individuals and should be screened for eradication therapy.

2016 ◽  
Vol 23 (08) ◽  
pp. 907-911
Author(s):  
Farrukh Zahra ◽  
Muhammad Younis ◽  
Uzma Nisar

Objectives: To determine the frequency of nonulcer dyspepsia in patientspresenting with the peptic ulcer like symptoms and to determine the effect of H. pylori eradicationon dyspeptic symptoms and the effect of six weeks trial of proton pump inhibitor as treatmentmeasure. Study design: Cross-sectional study. Setting: Combined Military hospital Quetta,Department of medicine. Period: Six months from Oct, till March 2009. Subjects and Methods:Patients coming to medicine department with complaints of dyspepsia. Results: Total no ofpatients were 145 out of which male were 90 while 55 were females. The mean age was 29.68+ 4.53. These subjects were given H pylori eradication therapy and response was graded aspatients responded or no response. 89 subjects (61.4%) responded to H pylori eradicationtreatment while 56 subjects (38.6%) showed no symptomatic benefit. Non responder toeradication i.e., 37 males and 36 females were given further six week treatment with omeprazole,and subjective response to treatment was graded as complete resolution found in 31 patients (21.4% ), while partial resolution was present in 15 patients (10.3%). 07 patients (4.8%) showedno improvement while 03 patients (2.1%) showed worsening of symptoms. Conclusions: Theprevalence of non-ulcer dyspepsia is high among symptomatic individuals. The response toH pylori eradication was significant. Non responders also showed considerable symptomaticbenefit with PPI. Therefore, individuals with recurrent dyspeptic symptoms should be given trialof H. pylori eradication.


2018 ◽  
Vol 25 (12) ◽  
pp. 1905-1909
Author(s):  
Shahnawaz Tahir ◽  
Riaz Hussain Awan ◽  
Seema Nayab ◽  
Khadim Hussain Awan

Objectives: To determine the frequency & histopathological type of gastric pathology in individuals presenting with epigastric pain. Period: Six months from July to Dec 2017. Study Design: Cross sectional study. Setting: Department of Gastroenterology, Liaquat National Hospital Institute for Postgraduate Medical Studies and Health Sciences, Karachi. Patients and Methods: The total of 333 patients had history of epigastric pain were included in this study. The specimen for mucosal biopsy was taken during endoscopy and sent to the clinical laboratory for histopathology examination for the classification. All the information was entered and saved on the annexed / proforma. Results: The mean ±SD of age for all thepatients was 41.31±7.89 years. Frequency of gastric pathology in patient presenting with epigastric pain was 51.35% (171/333) cases. There were 171 histopatholocal diagnoses, non-Noeplastic lesion was confirmed in 99.42% (170/177) and one case had Noeplastic lesion. Regarding the type of gastric pathology, 25.73 % (44/171) had gastric ulcer, 48.54 (83/171) was H. pylori gastric and 25.15% (43/171) had chronic gastritis. Conclusion: The study frequency of gastric pathology in patient presenting with epigastric pain was high.


2020 ◽  
Vol 27 (09) ◽  
pp. 1862-1866
Author(s):  
Muhammad Nasir Ali ◽  
Muhammad Khalid Chishti ◽  
Kashif Siddiq ◽  
Muhammad Hamayun Hameed ◽  
Muhammad Tayyab Waheed ◽  
...  

Objectives: To determine the failure of DHS (dynamic hip screw) in terms of lag screw cutout. Study Design: Hospital Based Cross Sectional study. Setting: BVH and Civil Hospital Bahawalpur. Period: From 2013 to 2018. Material & Methods: 273 patients of both genders with age more than 50 years having stable intertrochanteric fractures were included in this study. With the help of C arm, the best possible anatomical reduction and rigid internal fixation was done with 135 degree DHS. Lag screw position and TAD determined on first postoperative day on radiographs (Anteroposterior & Lateral). Failure of fixation was determined on the radiographs during follow up. Lag screw cut-out was the projection of the screw from the femoral head by more than 1mm. Results: The mean age of the patients was 68.6 years (50-88). There were 132 (51.1 %) males and 126 (48.8%) females. Overall lag screw cutout rate was 11.2%. 21(30.8%) had screw cutout while 47 (69.1%) healed successfully among 68 patients with TAD ≥ 25mm. On the other hand 8(4.2%) had screw cutout while 182 (95.7%) healed successfully among 190 patients with TAD < 25mm. Middle middle and inferior middle position had highest success rate (˃ 92%) while inferior posterior position had highest cutout rate (36.2%). Among different age categories high failure rate (17.8%) seen in patients more than 70 years. Conclusion: The incidence of lag screw cutout is 11.2 % and risk of cutout can be minimized by placing lag screw in middle middle or inferior middle position and keeping the TAD < 25mm. More attention during follow up should be paid to patients with age ˃ 70 years.


2021 ◽  
Vol 28 (04) ◽  
pp. 548-551
Author(s):  
Maria Saleem ◽  
Asim Khurshid ◽  
Amna Wajdan ◽  
Muhammad Salman Zafar

Objectives: To analyze the clinical profile, etiologies and outcome of seriously ill patients admitted in Pediatric Intensive Care Unit (PICU). Study Design: Cross Sectional study. Setting: PICU of Nishtar Medical Hospital, Multan, Pakistan. Period: January 2018 to December 2018. Material & Methods: During the study period, a total of 150 children, aged 1 to 12 years, with better prognosis and post-surgical cases requiring intensive care were registered. Age, gender, cause for hospitalization (clinical, surgical or emergency), length of PICU stay, diagnosis and outcome were recorded for all patients. Results: During the year of the study, 83 (55.3%) children were noted to be male. The mean age was 56.9+12.5 months. Mechanical ventilation was done in 62 (41.3%) patients. Major indications for admission to the PICU were respiratory disorders (21.5%), followed by sepsis (11.4%) and meningitis (8.1%). Majority, 80 (53.3%) patients improved and were shifted to ward and later discharged while 27 (18.0%) expired. Conclusion: Most of the children admitted in the PICU were male, aged below 5 years. Most common indication for admission in the PICU were respiratory disorders followed by sepsis and meningitis.


2017 ◽  
Vol 24 (12) ◽  
pp. 1894-1898
Author(s):  
Shahid Ali Mirani ◽  
Syed Yousif Ali Shah ◽  
Muhammad Ameen Sahito

Objectives: This study was carried out to evaluate the dental students’perception about condition of their gums and teeth and prevalence of dental caries. StudyDesign: Descriptive cross sectional study. Setting: Liaquat University of Medical and HealthSciences. Period: July 2011 to December 2011. Material and Method: The sample size was200 students comprising of both male and female. Clinical Oral examination was performedwith the help of mouth mirror and explorer in dental chair. The perception of dental studentsabout condition of their gums and teeth was obtained through questionnaire. Results: Theresults revealed that 25 % of students in present study had dental decay. The mean DMFT scorewas 0.625. Moreover, the mean DMFT score for male and female students was 0.658 and 0.576respectively. The results about distribution of DMFT components indicated that the decayed(D) teeth were in greatest number followed by filled (F) and missed (M) teeth. Conclusion:There was statistically no significant association between dental caries and gender. Moreover,prevalence of dental caries was significantly different between those who perceived their gumsand teeth condition excellent and good compared to the students who perceived their gumsand teeth condition as poor.


F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 1054
Author(s):  
Rawda Mohmmed Elhassan Ali Noor ◽  
Wafaa Mohammed Abdalla ◽  
Ahmed Bakheet Abd Alla ◽  
Ahmed Ibrahim Hashim

Background: Helicobacter pylori causes a major health problem worldwide; more than half of the world’s population are infected with this pathogen. The diagnosis of the infection was initially made through invasive methods, but now non-invasive methods have been developed to make diagnosis easier. This study aimed to screen the presence of H.pylori antibodies and antigen among symptomatic and asymptomatic patients at Tamboul City in Gezira State. Methods: A cross-sectional study was conducted in Tamboul city, Gezira State, Sudan between March 2016 and December 2019 to compare between antigen and antibody tests results used for diagnosis of H. pylori infection among symptomatic and asymptomatic Sudanese patients. Stool and blood samples were collected and analyzed for presence of antigen and antibodies to H. pylori using immunochromatography (ICT) cards. Results: Serum and stool samples were collected from 100 patients; 50 were symptomatic and 50 were asymptomatic. In symptomatic patients, 18/50 (36%) were men (32; 64%, women) with mean age of 16.7±24.6 years. In this group, 35/50 (70%) showed positive results for stool antigen, while 30/50 (60%) were positive for serum antibodies. In asymptomatic patients, 19/50 (38%) were men (31; 62%, women) with mean age of 16.7±20.4 years. In this group, 18/50 (36%) were positive for stool antigen and 25/50 (50%) for serum antibodies. There was a significant association between antigen results and patient group (P=0.001), but there was an insignificant association between antibodies results and patient group (P=0.317). Age group, history of infected persons in the family, blood group, and previous treatment were all not associated with H. pylori infection (P≥0.05). Conclusion: The frequency of H. pylori antigen was higher than antibodies in symptomatic patients, while the frequency of H. pylori antibodies was higher than antigen in asymptomatic patients.


2018 ◽  
Vol 25 (03) ◽  
pp. 396-399
Author(s):  
Asim Amjad ◽  
Ubaid Ullah ◽  
Iqbal Ahmad Azhar

Background: The signs and symptoms of pneumonia are often nonspecificand widely vary based on the patient’s age and the infectious organisms involved. IMNCI hasimproved case improved diagnose of pneumonia. This study was conducted to study thefrequency of correctly diagnosed cases of severe pneumonia by IMNCI classification in childrenbetween 2 – 59 months of age. Study Design: Cross sectional study. Setting: Departmentof Pediatrics, Mayo Hospital, Lahore. Period: January to June 2013. Methodology: Total155 cases were included through Non probability purposive sampling. Chest radiographswere taken within the first 6 hours from Radiology Department and reports were obtained forevidence of pneumonia. Data was entered and analyzed in SPSS version 16. Age, weight,height were presented as mean ± standard deviation. Sex and radiological findings of severepneumonia were presented as frequency tables and percentages. Results: The mean age ofpatients was 12.76±11.54 months. There were 47.1% females and 52.9% males. Out of 155patients 134(86.5%) had pneumonia on CXR where as only 21(13.5%) appeared with normalstatus which were already positive on IMNCI. Only 21 (13.5%) appeared with bilateral patchof consolidation, 62 (40%) appeared with Unilateral patch of consolidation, 11 (7.1%) wereappeared with Bronchopneumonia, 30 (19.4%) were appeared with lung collapse condition and(12.9%) were appeared with Pleural Effusion. Conclusion: Clinical assessment of pneumonia inchildren on IMNCI is equivalent to the assessment on chest X-ray.


Author(s):  
Md Shabab Hossain ◽  
Subhasish Das ◽  
S M Khodeza Nahar Begum ◽  
M Masudur Rahman ◽  
Ramendra Nath Mazumder ◽  
...  

Abstract Aim There is insufficient knowledge on the * duodenal histology and Helicobacter pylori infection in malnourished Bangladeshi children. Therefore, we attempted to explore the prevalence of H. pylori infection and duodenal histopathology in 2-year-old chronic malnourished Bangladeshi slum-dwelling children and investigate their association with dyspeptic symptoms. Methods This cross-sectional study was conducted using the data of the Bangladesh Environmental Enteric Dysfunction study in an urban slum of Dhaka, Bangladesh. With a view to address the association of environmental enteric dysfunction (EED) with stunting, upper gastrointestinal endoscopy was performed on 54 chronic malnourished children {31 stunted [length-for-age Z-scores (LAZ) &lt;−2] and 23 at risk of stunting (LAZ &lt;−1 to −2)} aged between 12–24 months and the mucosal biopsies were subjected to histopathological examination after obtaining proper clinical history. Stool antigen for H. pylori (HpSA) was assessed to determine H. pylori status. Results In all, 83.3% (45/54) of the children had histopathological evidence of duodenitis. Chronic mild duodenitis was found to be the most prevalent form of duodenitis (53.7%) in the children. Only 8.9% (4/45) of the children with duodenitis had dyspepsia (p &lt; 0.05). The 14.8% (8/54) of the children were found positive for H. pylori infection. Logistic regression analysis revealed children positive for HpSA had significant association with dyspepsia (OR 9.34; 95% CI 1.54–56.80). Conclusions The number of chronic malnourished children suffering from duodenitis was found to be very high. Majority of these children was asymptomatic. Children positive for HpSA had significant association with dyspeptic symptoms.


2019 ◽  
Vol 26 (03) ◽  
Author(s):  
Aysha Khudija ◽  
Attia Rabbani ◽  
Huma Zafar Dar

Objectives: To determine the frequency of expulsion of post PPIUCD after spontaneous vaginal delivery. Study Design: Cross sectional study. Setting: Department of Obstetrics & Gynaecology Unit-II, Lady Willingdon Hospital, Lahore. Period: October 2013 to October 2014. Methodology:  In this study the pregnant females delivering vaginally at any age of gestation were included. The cases were selected irrespective of gravida, parity and having age range of 18 years or more. The cases undergoing any instrumentation or surgical intervention were excluded. Then these cases were followed for 6 weeks postpartum and X ray was done to confirm the position of IUCD and absence of the radio opaque shadow reveal its expulsion. Results: In this study 150 pregnant females were selected. The mean age of the subjects was 29.13±4.46 years. PPIUCD expulsion was seen in 11 (7.33%) of cases. PPIUCD expulsion was more commonly seen in age group more than 30 years affecting 7 (8.33%) of cases with p=0.24. PPIUCD was also more often seen in cases with multiparous women where it was observed in 08 (7.55%) cases with p= 0.78. Conclusion: Expulsion of PPIUCD is not uncommon and is more common in cases with age more than 30 years and multiparous women.


2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Edity Namyalo ◽  
Luke Nyakarahuka ◽  
Matthias Afayoa ◽  
Joel Baziira ◽  
Andrew Tamale ◽  
...  

Background. Helicobacter pylori (HP) infection is extremely common worldwide, with almost half of the world’s population infected. In Uganda, no study has been done on the trends of the prevalence of H. pylori infection in the affluent population. Therefore, this retrospective cross-sectional study aimed at determining the trend of H. pylori prevalence among affluent patients presenting with gastrointestinal (GIT) symptoms whose stool samples were tested at selected AAR clinics in Kampala area. Patients were tested for Helicobacter pylori infection using the stool antigen test between January 2015 and December 2019. Results. The overall 5-year H. pylori prevalence was 35.7% (1298/3634). The prevalence was higher in males (36.0% (736/2044)) than in females (35.4% (562/1590)), although not statistically significant (OR = 0.97, p = 0.680, 95% CI: 0.84–1.11). The prevalence of H. pylori infection was significantly higher (39.4%) among patients who belonged to the age group of 19–35 years (OR = 1.49, p < 0.001 , 95% CI: 1.22–1.82). The prevalence for H. pylori among the age group of 19–35, the most productive age, could be attributed to work-related factors such as stress. The highest prevalence (43.4%) was recorded in 2018 and the lowest (21.4%) in 2015; however, the trend of H. pylori infection in the 5 years was fluctuating. Conclusion. H. pylori infestation is a preserve of not only the poor but also the elites. Stressful factors, especially in the age group of 19–35 years, should be appropriately managed.


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