scholarly journals FREQUENCY AND SEVERITY OF LIVER INVOLVEMENT IN DENGUE VIRUS INFECTION.

2019 ◽  
Vol 26 (07) ◽  
pp. 1074-1078
Author(s):  
Masood Tareen ◽  
Riaz Hussain Awan ◽  
Seema Nayab ◽  
Khadim Hussain Awan
Keyword(s):  
Dengue Fever ◽  
Liver Enzymes ◽  
Early Recognition ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Liver Involvement ◽  
Care Hospital ◽  
Cross Sectional ◽  
Study Setting

Objectives: To determine the frequency & severity of liver involvement in dengue infection among adults at tertiary care hospital. Period: Six months (9th May 2016 to 9th Nov 2016). Study Design:  Cross-sectional study. Setting: Department of Gastroenterology and Department of Medicine Liaquat National Hospital, Karachi. Patients and Methods: Results: A total of 343 patients with Dengue fever were selected to conduct this study with mean age of 34.67±9.09 years. Mean duration of the fever was 7.31±1.62 days. Mean duration of hospital stay of the patients came out to be 3.50+0.82 days. Severity of liver enzymes derangement was mild in 80 patients (23%), moderate in 246 (72%) & severe in 17(5%). Mortality was seen in 14% (47 patients) & 100% mortality was seen in dengue fever patients with severely deranged Liver enzymes. Conclusion: Dengue fever patients with deranged liver enzymes had statistically worse outcome thus can lead to early recognition of high risk cases.

scholarly journals FREQUENCY OF FEMORAL FRACTURES;

2012 ◽  
Vol 19 (01) ◽  
pp. 011-014
Author(s):  
RANA MUHAMMAD ADNAN ◽  
Muhammad Irfan ZIA ◽  
JAHANZAIB AMIN ◽  
Rafya Khan ◽  
Saleem Ahmed ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Femoral Fractures ◽  
Cross Sectional Study ◽  
Cognitive Disability ◽  
Care Hospital ◽  
Cross Sectional ◽  
Hospital Design ◽  
Femur Fractures ◽  
Study Setting

Background: To compare the frequency of various types of fractures of femur in patients less than and more than 40 years ofage in a tertiary care hospital. Design: Descriptive cross-sectional study. Setting: Emergency department. Period: January 2009 to April 2011.Method: A total of 1756 patients were divided into two groups with respect to age. Then they were further categorized according to the part offemur involved, and compared in both age groups. Results: The study was conducted on a total number of 1756 patients over a period of 2 yearsfrom 2009 to 2011. 51.1% patients were less than 40 years of age and 48.9% patients were more than 40 years of age. In patients more than 40years of age, pertrochanteric fracture was most common (86.40%). In patients less than 40 years of age, mid shaft of femur was most commonregion involved (87.02%). Conclusions: The incidence of proximal femur fractures is high in elderly patients because of several factors likeosteoporosis, visual impairment and cognitive disability. Whereas incidence of fractures of mid-shaft of femur is more common in youngpatients.

scholarly journals Clinico-Laboratory Observations and Outcome of Dengue Infection In a Tertiary Care Hospital of Western Nepal: An Observational Cross-Sectional Study

2018 ◽  
Vol 5 (2) ◽  
pp. 3-7
Author(s):  
Niraj Kumar Jaiswal ◽  
Shatdal Chaudhary ◽  
Nagendra Chaudhary
Keyword(s):  
Tertiary Care Hospital ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Severe Thrombocytopenia ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Rapid Urbanization ◽  
South West

INTRODUCTION: Dengue fever (DF) is highly prevalent in tropical and subtropical countries all over the world. This study was done to study the clinico-laboratory profile of DF patients and their outcomes in a tertiary care hospital of western Nepal.MATERIAL & METHODS:  A prospective observational cross-sectional study conducted over 6 months (October 2016 to March 2017) in patients admitted to medical inpatient ward of a tertiary care referral hospital located at south west Nepal. All febrile patients underwent dengue antibody (IgM) testing. Patient details, clinical manifestations and laboratory parameters were recorded. Descriptive analysis was done as mean and percentage.RESULTS: Out of total 2653 hospital admissions, 1274 patients (male: 780, female: 494) presented with fever. Forty patients between 17 years to 84 years (Mean age ± SD: 40.3±17 years) were diagnosed as DF. All the age groups were almost equally affected. The average duration of hospital stay was 5.4±3.2 days. Fever (n=40, 100%), body ache (n=29, 74.4%) and headache (n=28, 70%) were three leading complaints in dengue patients. Only 22.5% (n=9) of the patients had thrombocytopenia (mild and moderate). Severe thrombocytopenia was not noticed. Only 10% of total dengue cases received platelet transfusion. The mean platelet count increased from day one to day seven gradually. All the patients recovered.CONCLUSION: DF is a well-established vector-borne disease in south west Nepal; may be due to rapid urbanization and poor hygiene facility. Appropriate disease control programme emphasizing on vector surveillance and control, early clinical diagnosis and treatment reduces the dengue-related deaths.Journal of Universal College of Medical Sciences (2017)Vol.05 No.02 Issue 16, page: 3-7

scholarly journals Mortality among organophosphate poisoning patients presenting with low Glasgow coma scale score at A Tertiary Care Hospital.

2020 ◽  
Vol 27 (10) ◽  
pp. 2187-2192
Author(s):  
Muhammad Ali ◽  
Vinod Kumar ◽  
Shafique Ahmed ◽  
Hina Iram ◽  
Sagheer Ahmed ◽  
...  
Keyword(s):  
Medical Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Organophosphate Poisoning ◽  
Care Hospital ◽  
Cross Sectional ◽  
Practical Tool ◽  
The Subject ◽  
The Mean ◽  
Study Setting

This study is designed to assess the mortality in OPP patients with low GCS scores. Study Design: Cross Sectional study. Setting: Jinnah Postgraduate Medical Center. Period: From 1st February 2018 to 31st August 2018. Material & Methods: Included patients with low GCS, both genders and age of 18-60 years diagnosed with OPP. Their GCS was calculated and the outcome was determined in terms of mortality. Results: Out of 70 patients, the mean age was 35.2+16.5 years with the majority (62.9%) <30 years. 62.9% of these were males. Most (57.1%) of them presented after ingestion of <15mL of OP, 60% had the poisoning for >60 minutes, and the majority (74.3%) had taken it orally. When the GCS was computed, 81.40% had that of >5, while the mean came out to be 6.64 ±1.43. The mortality rate here was 17.10%. Conclusion: GCS toll can be a helpful and practical tool in assessing the mortality among the patients of OPP. However, because of the limited literature on the subject further studies are recommended to improve its validity.

scholarly journals A study of clinical profile of patients with Dengue fever at a tertiary care hospital

2018 ◽  
Vol 5 (1) ◽  
pp. 202 ◽  
Author(s):  
Sreenivasulu T. ◽  
Jahnavi K.
Keyword(s):  
Dengue Fever ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Care Hospital ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Presenting Symptoms

Background: Dengue is the most common fever. Among all flavi-viruses, it is the most common. It can cause around 50-100 million infections. Every year 2-5 lakh cases of Dengue hemorrhagic fever occur. The objective of the research was to study clinical profile of patients with Dengue fever at a tertiary care hospital.Methods: Present study was cross sectional study. The patients were interviewed and examined at one point of time and later they were never followed which is similar to the cross-sectional study design. Present study was carried out in the hospital. This was done in the department of General Medicine of a tertiary care hospital. Present study was carried out over a period of one year.Results: In the present study, there were 78 males and 22 females. The sex ratio was 3.5:1. Maximum number of males (29.5%) was in the age group of 15-25. Among females, the maximum (40.9%) were in the age group of 26-35 years and 46-55 years (9%). The most common presenting symptom was fever in all cases followed by headache in 90%. Among bleeding manifestations, epistaxis, gum bleeding and hematuria (15%) were the common symptoms. Most patients presented with generalized lymphadenopathy in 52%. 56 patients showed only hepatomegaly and 46 splenomegaly, and 30 patients showed hepato splenomegaly. 99 showed leucopenia and 10 were anemic and 25 showed platelet count less than 1,50,000cells/cumm.Conclusions: Males were commonly affected. Younger age group of 15-25 was most commonly affected and fever and headache were the most common presenting symptoms. These findings help physicians in early diagnosis of dengue by suspecting these features as of dengue and can prevent morbidity and mortality associated with dengue.

scholarly journals Clinico-laboratory profile and outcome of dengue fever among children attending a tertiary care hospital of rural Telangana, India

2020 ◽  
Vol 7 (2) ◽  
pp. 382 ◽  
Author(s):  
V. Shekar ◽  
K. Praveen Kumar ◽  
C. Soren ◽  
K. Venkataramana Reddy ◽  
N. Dharani
Keyword(s):  
Dengue Fever ◽  
Tertiary Care Hospital ◽  
Early Recognition ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Warning Signs ◽  
Severe Dengue ◽  
Severe Thrombocytopenia ◽  
Care Hospital ◽  
Presenting Symptoms

Background: Dengue is a self-limiting, vector-borne disease transmitted by Aedes mosquito, causing a major public health threat globally. The objective of this study is to assess the clinical profile and outcome of the dengue infection in children less than 14 years of age September 2018 to August 2019 at the Pediatric Department of S.V.S. Medical College, the tertiary care hospital in Mahabubnagar, Telanagana.Methods: Prospective study of 82 hospitalized children of <14 years with the diagnosis of dengue illness. Children with diagnosis of dengue were classified further in to two groups as per WHO guidelines, Non-severe dengue fever (probable dengue, dengue with warning signs) and ‘Severe Dengue’ (Dengue Haemorrhagic Fever and/or Dengue Shock Syndrome (DHF/DSS). A separate questionnaire form used for documenting clinical history, laboratory parameters. Haematological parameters were noted, chest x-ray, ultra-sonogram in required cases was done. Children were managed as per WHO protocol. The outcomes of the cases were mentioned as discharge, left against medical advice and death.Results: A total of 82 children with dengue were divided in to 55(67%) non severe dengue and 27(33%) severe dengue with males 56(68.2%) and females 26(31.7%). The most common age of presentation was between 6-10 years 34(41.5%). Fever 73(89%) was the most common presenting symptoms. Pleural effusion and hepatomegaly were the commonest clinical findings 28(34.1%) each, which were more among the severe dengue patients. Gall bladder edema 29(35.3%) was the most common ultra-sonogram finding. Significant elevation of transaminases (SGOP, SGPT) was seen in 39(47.5%). Severe thrombocytopenia was observed in 22(26.8%) children. Management was by administration of colloids and crystalloids.Conclusions: Dengue is a global problem. Presenting features include high grade fever, vomiting, abdominal pain, skin rash. Early recognition of symptoms and proper management can reduce the mortality.

scholarly journals Extra-Articular Manifestations of Rheumatoid Arthritis & its relation with Treatment Outcome: a tertiary care hospital experience

KYAMC Journal ◽  
2017 ◽  
Vol 6 (1) ◽  
pp. 570-573 ◽  
Author(s):  
Nazma Akter ◽  
Nazmul Kabir Qureshi ◽  
Md Azizul Hoque ◽  
Md Mujibur Rahman
Keyword(s):  
Rheumatoid Arthritis ◽  
Treatment Outcome ◽  
Tertiary Care Hospital ◽  
Early Recognition ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
American College Of Rheumatology

Objective: This study was done to determine frequency of extra-articular manifestations (ExRA) in patients with rheumatoid arthritis (RA) and its relation with treatment outcome in a tertiary care hospital, Dhaka.Methods: A cross sectional study was conducted upon 50 patients of rheumatoid arthritis of both gender aged ranging 30 to 60 years attending different medicine units of Shaheed Suhrawardy Medical College & Hospital during the period of May to October, 2011 who fulfilled the 1987 American College of Rheumatology criteria for RA. Demographic characteristics, extra-articular manifestations were recorded and some information was gathered by document review according to DAS28 (disease activity score 28.)Results: Among 50 patients female to male ratio was 9:1. The average age was 43.72±10.95 (SD) in years with maximum age 60 years and minimum age 30 years. Extra-articular manifestations were reported in 86.0% of patients. Hematological involvement (82%) was the most common extra-articular manifestation. Average DAS 28 was more in patients who had extra-articular manifestations than patients who had no extra -articular manifestation.Conclusion: Significant proportion of patients with female predominance visited at a tertiary care hospital due to RA. ExRA were present in a substantial proportion of a hospital based sample and is generally associated with a worse disease outcome. Hematological system involvement was the commonest. Early recognition and treatment are important to decrease disease activity.KYAMC Journal Vol. 6, No.-1, Jul 2015, Page 570-573

scholarly journals Clinical profile of Dengue fever in an urban tertiary care hospital in South India

2019 ◽  
Vol 6 (3) ◽  
pp. 618
Author(s):  
Dhivya P. ◽  
Monica A. ◽  
Jayaramachandran S.
Keyword(s):  
Dengue Fever ◽  
Clinical Features ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Viral Disease ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
The World ◽  
Study Population

Background: Dengue is among the most common flavivirus infections in the world. Today dengue ranks as the most important mosquito- borne viral disease in the world. Current estimates report that, at least 112 countries are endemic for Dengue and about 40% of the world populations (2.5-3 billion people) are at risk in tropics and subtropics. Annually 100 million cases of dengue fever and half a million cases of DHF occur worldwide. The clinical features are noted to be different in varying demographics of the world outlining the importance of bringing out data from different parts of the world, so clinicians are better equipped to anticipate the problems associated with clinical dengue.Methods: The study was conducted over a period of 2 years at a tertiary care hospital in urban Bengaluru, India. A cross sectional study of a total of 250 patients was done. They were diagnosed to be positive for dengue serology (NS1 or IgM) before including them in the study. Clinical features, haematological, biochemical and radiological parameters were assessed.Results: Out of 250 patients with dengue fever, the most common symptoms were fever (100%), headache (94.4%) and myalgia (97.2%). Bleeding manifestations were noted in 11.6% of the patients. Bradycardia was noted in 14.8% of the study population. Leukopenia was noted in 36% of the study population. Increased SGOT was seen in 59.6% and increased SGPT in 52.8% of the 250 subjects. The clinical outcome of the 250 patients of dengue fever was classical dengue fever in 86.8%, DHF in 11.6%, DSS in 0.8% and death in 0.8%.Conclusions: All patients with dengue fever present with fever. Other common features noted were headache, myalgia. Bleeding manifestations are to be looked out for. Rare but important features that a clinician must be vigilant to look for are bradycardia and leucopenia.

scholarly journals Prevalence of pyogenic meningitis in a Tertiary Care Hospital of Sindh.

2020 ◽  
Vol 27 (10) ◽  
pp. 2117-2121
Author(s):  
Habibullah Siyal ◽  
Asif Nadeem Jamali ◽  
Zamir Ahmed Qambrani
Keyword(s):  
Early Recognition ◽  
Local Population ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Health Sciences ◽  
P Value ◽  
Care Hospital ◽  
Pyogenic Meningitis ◽  
Cross Sectional ◽  
Common Clinical Presentation

Objectives: The current study aimed to find out the prevalence of pyogenic meningitis in the local population of Peoples University of Medical and Health Sciences Hospital Nawabshah. Study Design: Descriptive Cross Sectional study. Setting: Pediatric Ward of People University of Medical and Health Sciences Hospital, Nawabshah. Period: 1 year from November 2018 to October 2019. Material & Methods: Using self-designed questionnaire. Patient’s samples were send for relevant investigations i.e. Blood culture and CSF examination and their results were recorded in proforma. Statistical Package for Social Science (SPSS) version 21 was used for data analysis. Results: Mean age of the children was 7 Years with a standard deviation of 2.4 years. 57% of the sample consist of boys while 43% were girls. Diagnosis of pyogenic meningitis was confirmed in 52.08% of the cases and fever was present in 100% cases and was the most common clinical presentation followed by headache (67%), Vomiting (44%) and fits (28%). Mean protein level was 235 mg/dl in the diagnosed cases. Mean sugar level in CSF of diseased children was 35 mg/dl with significant p-value of 0.0005. Conclusion: Pyogenic meningitis is highly prevalent that is 52.08% in current study. Its morbidity and mortality can be reduced by early recognition and prompt treatment.

scholarly journals Study of electrolytes in patients of Dengue in a tertiary care hospital in India

2019 ◽  
Vol 6 (3) ◽  
pp. 763
Author(s):  
Prakash Ram Relwani ◽  
Neelam N. Redkar ◽  
Deepanshu Garg
Keyword(s):  
Demographic Data ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Clinical History ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Electrolyte Disturbances ◽  
Low Platelet Count

Background: Dengue is a mosquito borne viral infection. It is the most common arboviral disease globally. In the year 2017, India had 1,53,635 cases of dengue with 226 deaths. Electrolyte disturbances reported in dengue infection are hyponatremia, hypokalaemia and hyperchloremia. Considering the serious nature of effects of dyselectrolytemias and high incidence of dengue in India, it is necessary to have a thorough understanding about electrolyte disturbances in Dengue, so as to predict, diagnose and treat them accordingly.Methods: This study was performed in a tertiary care centre in Mumbai, India. The study was a prospective observational cross-sectional study. 150 Patients diagnosed with Dengue were enrolled for the study. Patients’ demographic data, clinical history, examination findings and investigations including electrolyte values were recorded and analysed.Results: A higher incidence of dengue was seen in young age group among admitted patients (74%). Hyponatremia (45.33%) and Hypokalaemia (10.60%) were more commonly observed than hypernatremia (3.33%) and hyperkalaemia (3.33%). Hypochloraemia (6.66%) was seen slightly more than hyperchloraemia (6.00%). Fever was Present in 98.66%, retro orbital headache in 86.66%, vomiting in 56.00%, joint pain in 69.00%, lethargy in 70.66%, breathlessness in 36.00%, bleeding in 8.66%, abdominal pain /tenderness in 18.00%. 85.00% had low platelet count, 30.66% had low hemoglobin and 36.66% had leucopenia. Haematocrit was found to be less in 27.33% and high in 1.33%.Conclusions: From the above results we concluded that, there is a need to have a degree of suspicion about dyselectrolytemias while managing patients with Dengue. Also, patients need to be subjected to necessary lab investigations early during management so that if abnormalities are found, they can be promptly and appropriately managed as some of these abnormalities may lead to increased severity as well as mortality.

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