scholarly journals Family Support Relationship With The Level Of Anxiety In Cervical Cancer Patients Ulin Hospitals Banjarmasin

2017 ◽  
Author(s):  
Fadhiyah Noor Anisa ◽  
Elvine Ivana Kabuhung ◽  
Ruthiana Amia
Keyword(s):  
Cervical Cancer ◽  
Family Support ◽  
Cancer Patients

scholarly journals Hubungan Dukungan Keluarga Dengan Kualitas Hidup Pasien Kanker Serviks : Literature Review

2021 ◽  
Vol 1 ◽  
pp. 279-286
Author(s):  
Ameliya Tri Yuliana ◽  
Emi Nurlaela
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Literature Review ◽  
Family Support ◽  
Cancer Patients ◽  
P Value ◽  
Fisher Exact Test ◽  
Chi Square ◽  
Exact Test

AbstractCervical cancer is a chronic which is commonly experienced in woman. Patient with cervical cancer need support,especially family support in order to improve their quality of life. This study aims to examine the correlation between family support and quality of life for cervical cancer patients. It is a quantitative, correlative descriptive used a literature review. 2 articles tested by chi square, two others tested by sperman rank, and one article tested by statistic fisher exact test. It used a Google Schoolar to find out the articles in inclusive and eclusive criteria with a family support, quality of life, and cervical cancer as the keywords. The critical analysis instrument used a strobe consisting of 22 questions. The results of the literature review of these articles showed that there was 48 (21%), high family support 16 (7%), good family support 40 (18%), good family support 22 (10%), poor quality of life 37 (16%), and adequate quality of life 51 (23%), meanwhile 24 (11%), obtained p value 0,05, which means that there is a correlation between family support and the quality of life of cervical cancer patients. There is a correlation between family support and the quality of life of cervical cancer.Keywords: family supports, quality of life, cervical cancer AbstrakKanker Serviks merupakan penyakit kronis yang dialami pada wanita. Pasien dengan kanker serviks membutuhkan dukungan seperti dukungan keluarga agar dapat meningkatkan kualitas hidup pada pasien dengan kanker serviks. Tujuan dari penelitian ini adalah untuk mengetahui hubungan dukungan keluarga dengan kualitas hidup pasien kanker serviks melalui literature review. Penelitian ini merupakan penelitian kuantitatif jenis deskriptif korelatif dengan pengambilan data menggunakan literature review dan 2 artikel menggunakan uji chi square, 2 artikel menggunakan uji spearman rank, 1 artikel menggunakan uji statistik fisher exact test. Cara mencari data base menggunakan Google Schoolar untuk menemukan artikel yang sesuai kriteria inklusi dan eksklusi dengan memasukan kata kunci dukungan keluarga, kualitas hidup, kanker serviks. Instrument telaah kritis menggunakan strobe yang terdiri dari 22 pertanyaan. Hasil penelitian literature review dari 5 artikel menunjukan ada dukungan keluarga 48 (21%), dukungan keluarga tinggi 16 (7%), dukungan keluarga baik 40 (18%), dukungan keluarga baik 22 (10%), kualitas hidup tidak baik 37 (16%), cukup 51 (23%), sedang 24 (11%), didapatkan p value ≤ 0,05 yang artinya terdapat hubungan dukungan keluarga dengan kualitas hidup pasien kanker serviks. Ada hubungan dukungan keluarga dengan kualitas hidup pasien kanker serviks.Kata Kunci : dukungan keluarga, kualitas hidup, kanker serviks.

scholarly journals Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Travis T. Sims ◽  
Molly B. El Alam ◽  
Tatiana V. Karpinets ◽  
Stephanie Dorta-Estremera ◽  
Venkatesh L. Hegde ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Radiation Therapy ◽  
Gut Microbiota ◽  
Cancer Patients ◽  
Gut Microbiome ◽  
Compositional Variation ◽  
Short Term ◽  
Microbiome Diversity ◽  
Term Survivor

AbstractDiversity of the gut microbiome is associated with higher response rates for cancer patients receiving immunotherapy but has not been investigated in patients receiving radiation therapy. Additionally, current studies investigating the gut microbiome and outcomes in cancer patients may not have adjusted for established risk factors. Here, we sought to determine if diversity and composition of the gut microbiome was independently associated with survival in cervical cancer patients receiving chemoradiation. Our study demonstrates that the diversity of gut microbiota is associated with a favorable response to chemoradiation. Additionally, compositional variation among patients correlated with short term and long-term survival. Short term survivor fecal samples were significantly enriched in Porphyromonas, Porphyromonadaceae, and Dialister, whereas long term survivor samples were significantly enriched in Escherichia Shigella, Enterobacteriaceae, and Enterobacteriales. Moreover, analysis of immune cells from cervical tumor brush samples by flow cytometry revealed that patients with a high microbiome diversity had increased tumor infiltration of CD4+ lymphocytes as well as activated subsets of CD4 cells expressing ki67+ and CD69+ over the course of radiation therapy. Modulation of the gut microbiota before chemoradiation might provide an alternative way to enhance treatment efficacy and improve treatment outcomes in cervical cancer patients.

Fas gene promoter –670 polymorphism in gynecological cancer

2006 ◽  
Vol 16 (Suppl 1) ◽  
pp. 179-182 ◽  
Author(s):  
M. Ueda ◽  
Y. Terai ◽  
K. Kanda ◽  
M. Kanemura ◽  
M. Takehara ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
Germ Line ◽  
Gynecological Cancer ◽  
Gene Promoter ◽  
Single Nucleotide ◽  
Increased Risk ◽  
Significant Difference ◽  
Germ Line Polymorphism

Single-nucleotide polymorphism at −670 of Fas gene promoter (A/G) was examined in a total of 354 blood samples from normal healthy women and gynecological cancer patients. They consisted of 95 normal, 83 cervical, 108 endometrial, and 68 ovarian cancer cases. Eighty-three patients with cervical cancer had statistically higher frequency of GG genotype and G allele than 95 controls (P= 0.0353 and 0.0278, respectively). There was no significant difference in the genotype or allele prevalence between control subjects and endometrial or ovarian cancer patients. The Fas −670 GG genotype was associated with an increased risk for the development of cervical cancer (OR = 2.56, 95% CI = 1.08–6.10) compared with the AA genotype. The G allele also increased the risk of cervical cancer (OR = 1.60, 95% CI = 1.05–2.43) compared with the A allele. Germ-line polymorphism of Fas gene promoter −670 may be associated with the risk of cervical cancer in a Japanese population.

scholarly journals Toward PET/MRI as one-stop shop for radiotherapy planning in cervical cancer patients

2021 ◽  
pp. 1-9
Author(s):  
Sahar Ahangari ◽  
Naja Liv Hansen ◽  
Anders Beck Olin ◽  
Trine Jakobi Nøttrup ◽  
Heidi Ryssel ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Patients ◽  
Radiotherapy Planning ◽  
One Stop

scholarly journals Total Antioxidant Capacity and Lipid Peroxidation Status in Cervical Cancer Patients Compared with Women Without Cervical Cancer in Bangladesh

2021 ◽  
Vol 19 (4) ◽  
Author(s):  
Taslima Nigar ◽  
Annekathryn Goodman ◽  
Shahana Pervin
Keyword(s):  
Oxidative Stress ◽  
Cervical Cancer ◽  
Lipid Peroxidation ◽  
Ascorbic Acid ◽  
Antioxidant Capacity ◽  
Cancer Patients ◽  
Total Antioxidant Capacity ◽  
Stress Index ◽  
Oxidative Stress Index ◽  
Total Antioxidant

Abstract Purpose Over the past several decades, research has suggested reactive oxygen species act as cofactors for cervical cancer development. The aim of this study is to evaluate the antioxidant and lipid peroxidation status in cervical cancer patients in Bangladesh. Methods From December 2017 to 2018, a cross-sectional observational study was conducted on 50 cervical cancer patients and 50 controls. Plasma levels of lipid peroxidation and total antioxidant capacity were measured. The Student’s t test was used for statistical analysis. P values less than 0.05 were taken as a level of significance. Results There was a significant reduction in total antioxidant levels in patients with cervical cancer, 972.77 ± 244.22 SD µmol equivalent to ascorbic acid/L, compared to normal controls, 1720.13 ± 150.81 SD µmol equivalent to ascorbic acid/L (P < 0.001). Levels of lipid peroxidation were found to be significantly higher in cervical cancer, 7.49 ± 2.13 SD µmol/L, than in women without cervical cancer, 3.28 ± 0.58 SD µmol/L (P < 0.001). The cervical cancer patients had significantly higher levels of oxidative stress index (0.83 ± 0.31) in comparison to controls (0.19 ± 0.04) (P < 0.001). Conclusion There was an increased oxidative stress index due to imbalance between lipid peroxidation generation and total antioxidant capacity in cervical cancer patients. Further studies are needed to explore the role of oxidative stress as a cofactor for cervical carcinogenesis.

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