scholarly journals Staphylococcal Meningitis as a Complication of Purulent Epiduritis

2020 ◽  
Vol 25 (3) ◽  
pp. 34-39
Author(s):  
N. V. Skripchenko ◽  
K. V. Markova ◽  
A. V. Astapova ◽  
E. Yu. Skripchenko ◽  
N. V. Marchenko
Keyword(s):  
Search Algorithm ◽  
Spinal Injury ◽  
Integrated Approach ◽  
Surgical Interventions ◽  
Reactive Protein ◽  
Purulent Meningitis ◽  
Appropriate Therapy ◽  
Examination Methods ◽  
Meningitis In Children ◽  
Inflammatory Changes

Purulent meningitis in children can be both primary and secondary. The latter are the result of various surgical interventions, ENT pathology, immunosuppressive therapy, as well as craniocerebral and spinal trauma, which justifies the need for an integrated approach to differential diagnosis to select the appropriate therapy tactics. The article presents a clinical observation of a child in whom purulent meningitis developed on the background of epiduritis, which was the result of a spinal injury. The diagnostic search algorithm is described. The authors concluded that if the patient has laboratory confirmed purulent meningitis and adequate therapy with clinical improvement in the patient’s condition, but persistent febrile fever, an increase in inflammatory changes in the blood amid a decrease in the level of acute phase inflammation proteins (C-reactive protein) and negative procalcitonin the test requires a search for a local inflammatory focus using additional examination methods, such as MRI or CT, as well as consultations with a neurosurgeon That allows you to specify the diagnosis and to determine the conduct of tactics, thus providing a favorable outcome.

Multi-AUV Underwater Cooperative Search Algorithm based on Biological Inspired Neurodynamics Model and Velocity Synthesis

2015 ◽  
Vol 68 (6) ◽  
pp. 1075-1087 ◽  
Author(s):  
Xiang Cao ◽  
Daqi Zhu
Keyword(s):  
Autonomous Underwater Vehicle ◽  
Search Algorithm ◽  
Integrated Approach ◽  
Underwater Vehicle ◽  
Ocean Currents ◽  
Ocean Current ◽  
Cooperative Search ◽  
Search Path ◽  
Negative Effect ◽  
Underwater Target

Ocean currents impose a negative effect on Autonomous Underwater Vehicle (AUV) underwater target searches, which lengthens the search paths and consumes more energy and team effort. To solve this problem, an integrated algorithm is proposed to realise multi-AUV cooperative search in dynamic underwater environments with ocean currents. The proposed integrated algorithm combines the Biological Inspired Neurodynamics Model (BINM) and Velocity Synthesis (VS) method. Firstly, the BINM guides a team of AUVs to achieve target search in underwater environments; BINM search requires no specimen learning information and is thus easier to apply to practice, but the search path is longer because of the influence of ocean current. Next the VS algorithm offsets the effect of ocean current, and it is applied to optimise the search path for each AUV. Lastly, to demonstrate the effectiveness of the proposed integrated approach, simulation results are given in this paper. It is proved that this integrated algorithm can plan shorter search paths and thus the energy consumption is lower compared with BINM.

scholarly journals Clinical Outcome of Single-Stage Decompression and Posterior Stabilization in Thoracolumbar Spinal Tuberculosis

2021 ◽  
Author(s):  
Patro Kumar Susanta ◽  
Nayak Biswaranjan ◽  
Krishnamurthy Holeppagol Balappa ◽  
Arun Kumar ◽  
Debabrata Biswal ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Spinal Injury ◽  
Spinal Tuberculosis ◽  
Thoracolumbar Spine ◽  
Single Stage ◽  
Posterior Stabilization ◽  
Surgical Interventions ◽  
Antitubercular Drugs ◽  
Impairment Score ◽  
Thoracolumbar Spinal Tuberculosis

Abstract Background Thoracolumbar spine constitutes the most common site for spinal tuberculosis. Though the treatment of spinal tuberculosis is antitubercular drugs initially, the patient with neurologic weakness warrants definitive surgical procedure of decompression and stabilization. Even though many investigators have reported favorable results with anterior decompression and stabilization surgery, due to the increased morbidity and complications, the posterior-only approach with decompression and stabilization has evolved as the operation of choice in recent time. Methods All patients aged between 18 and 70 years with clinically and radiologically proven symptomatic thoracolumbar spinal tuberculosis who failed with conservative treatment for 4 weeks or developed neurologic weakness between the treatments are included in this study. All patients were offered decompression and posterior stabilization with transpedicular screws and rods after explaining the above procedure. Clinical outcome was measured by modified Frankel grading; AIS (American Spinal Injury Association impairment score) grade impairment score; and pain assessment done with visual analog scale (VAS) pre- and postoperatively and at 3, 6, and 9 months of interval. Results The postoperative pain relief, neurologic improvement as per modified Frankel grade, AIS grade, and improvement in erythrocyte sedimentation rate and C-reactive protein were significant as compared with the preoperative status. The surgical interventions thus prove to have adequate relief to the patient and arresting the disease progression. The surgical outcome has very minimal intra- and postoperative complications. Conclusion Single-stage decompression and posterior stabilization in thoracolumbar spinal tuberculosis is safe, effective, and results in good clinical outcome. The advantages of surgery include thorough debridement, decompression, and achievement of spinal stabilization.

scholarly journals Serotypes of Bacteria Encountered in Childhood Purulent Meningitis in Children in Parakou (Benin) in 2011

2016 ◽  
Vol 06 (01) ◽  
pp. 109-119 ◽  
Author(s):  
Joseph Agossou ◽  
Julien Didier Adédémy ◽  
Alphonse Noudamadjo ◽  
Mahougnon Rachelle Mariette Houessou ◽  
Pierre Tsawlassou ◽  
...  
Keyword(s):  
Purulent Meningitis ◽  
Meningitis In Children

scholarly journals Identification of suitable websites for digital marketing – an approach using bio-inspired computing

2017 ◽  
Vol 7 (1.2) ◽  
pp. 239 ◽  
Author(s):  
B. Suresh Kumar ◽  
Deepshikha Bharghava ◽  
Arpan Kumar Kar ◽  
Chinwe Peace Igiri
Keyword(s):  
Search Algorithm ◽  
Cuckoo Search ◽  
Integrated Approach ◽  
Cuckoo Search Algorithm ◽  
Internet Usage ◽  
Digital Marketing ◽  
Assessment Criteria ◽  
Fast Pace ◽  
The Web ◽  
Selection Of

Due to the immense growth of Internet usage, the point of convergence has moved from physical to the web. The size of the web is increasing at a very fast pace to cater to the fast-evolving needs of the businesses, governments, and societies. However, selecting or identifying the best website is challenging. The practical issue to solve the problem comprises two parts. The first part is to identify the assessment criteria for appraising websites. Second is to evaluate the websites in the context of these assessment criteria and screen them to address a specific need. However, this objective is extremely complex and computationally extremely expensive. This research proposes an approach to identify websites from the Internet. The proposed integrated approach uses the Henry Garrett ranking method and cuckoo search algorithm for ranking and selection of websites for planning digital marketing campaigns.

scholarly journals Streptococcus pneumoniaemeningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine

2011 ◽  
Vol 22 (4) ◽  
pp. 137-141 ◽  
Author(s):  
Jennie Johnstone ◽  
Gregory J. Tyrrell ◽  
Thomas J. Marrie ◽  
Sipi Garg ◽  
James D. Kellner ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Mortality Rate ◽  
Conjugate Vaccine ◽  
Invasive Pneumococcal Disease ◽  
High Mortality ◽  
Clinical Characteristics ◽  
Pneumococcal Disease ◽  
Laboratory Data ◽  
Appropriate Therapy ◽  
Meningitis In Children

The objective of this study was to describe the epidemiology, clinical characteristics, microbiology and outcomes of patients of all ages withStreptococcus pneumoniaemeningitis between 2000 and 2004; two years pre- and postintroduction of anS pneumoniae7-valent conjugate vaccine program in Alberta in children younger than two years of age. The high mortality rate associated withS pneumoniaemeningitis, despite appropriate therapy, suggests that prevention ofS pneumoniaemeningitis is critical. Despite implementation of a PCV-7 program in Alberta, rates ofS pneumoniaemeningitis in children younger than two years of age is still high. Thus, continued research into safe and efficacious vaccines covering a broader range ofS pneumoniaeserotypes is necessary.OBJECTIVE: To describe the epidemiology, clinical characteristics, microbiology and outcomes of patients of all ages withStreptococcus pneumoniaemeningitis two years pre- and postintroduction of aS pneumoniae7-valent conjugate vaccine program in Alberta in children <2 years of age.METHODS: Between 2000 and 2004, all cases of invasive pneumococcal disease in Alberta were identified. From this cohort, patients withS pneumoniaemeningitis were identified by chart review. Clinical data, laboratory data and in-hospital outcomes were collected.RESULTS: Of the 1768 cases of invasive pneumococcal disease identified between 2000 and 2004, 110 (6.2%) hadS pneumoniaemeningitis. The overall incidence was 0.7 per 100,000 persons and remained unchanged over the study period. The rate in children <2 years of age appeared to fall over time, from 10.5 per 100,000 persons in 2000 to five per 100,000 persons in 2004, although there was insufficient evidence of a statistically significant time trend within any age group. Overall, the mean age was 30 years and 47% were male. In-hospital mortality was 20%, ranging from 6% in those ≤2 years of age to 31% for those ≥18 years of age, despite appropriate antimicrobial therapy.CONCLUSION: The high mortality rate associated withS pneumoniaemeningitis suggests that prevention by vaccination is critical. In children <2 years of age, there was a downward trend in the rate ofS pneumoniaemeningitis after implementation of theS pneumoniae7-valent conjugate vaccine program, but rates were still high.

scholarly journals Method of Enteral Insufficiency Syndrome Correction in Patients with Generalized Peritonitis

2021 ◽  
Vol 14 (3) ◽  
pp. 182-192
Author(s):  
Evgeny A. Korymasov ◽  
Sergey A. Ivanov ◽  
Mariya Kenarskaya ◽  
Maxim U. Khoroshilov
Keyword(s):  
Rating Scale ◽  
Study Groups ◽  
Albumin Level ◽  
C Reactive Protein ◽  
Surgical Interventions ◽  
Reactive Protein ◽  
Generalized Peritonitis ◽  
Group I ◽  
Group Ii ◽  
Insufficiency Syndrome

Introduction. Mortality in generalized peritonitis (GP) reaches 30%, and with the development of multiple organ failure, the lethal outcome is observed in 80-90% of cases. Enteral insufficiency syndrome (EIS) plays a leading role in the progression of generalized peritonitis. The aim of the study was to develop a differentiated approach of enteral insufficiency syndrome correction in patients with generalized peritonitis. Material and methods. This research was a retrospective prospective study. The study included 50 patients with GP, who received treatment at the Surgery Department of the Samara Regional Clinical Hospital in the period from 2017 to 2019. Depending on the chosen treatment tactics, the patients were divided into two clinical groups. Group I included 29 patients, admitted in the period from 2017 to 2018, who had received the standard GP treatment. A long-term endogenous intoxication in patients of this group associated with the progressive enteric failure led to the repeated surgeries; at the same time, a high frequency of postoperative complications was preserved. The analysis of the results in patients of Group I necessitated development of the therapeutic and diagnostic algorithm aimed at early diagnostics and timely correction of EIS. Group II included 21 patients with GP, admitted in the period from 2018 to 2019, who was treated using the new algorithm. Results. The objective criteria for the relief of EIS in GP in patients of the study groups were a decrease in the level of serum albumin and C-reactive protein, a significant decrease in the amount and qualitative change in the intestinal discharge via an intestinal tube, a decrease in the recovery time of the functions of the small intestine and start of defecation. On the 6th postoperative day, in patients of Group II there was no significant albumin level reduction in comparison with the 1st day of monitoring (28.310.77 g/l vs 37.334.69 g/l). Whereas in Group I the albumin level was significantly lower (19.30.51 g/l) than the same parameter in Group II, and in comparison with the 1st day of monitoring (19.30.51 g/l vs 39.56.05 g/l; р = 0.00001). On the 6th postoperative day, the C-reactive protein level differed significantly between the groups as well: Group I 104.7613.49 mg/l, Group II - 58.0029.05 mg/l, p = 0.003. The control of GP in patients of the Group I was reached after 4.52.5 repeated abdominal interventions, while in patients of Group II generalized peritonitis was arrested after 2.30.9 surgical interventions (p = 0.000171), which is 1.9 times less. Conclusions. The proposed algorithm of EIS control is based on the individual approach to the treatment of patients with GP. The developed EIS rating scale allows determining not only the degree and dynamics of the pathological process, but also monitoring the effectiveness of treatment options applied in a particular patient.

scholarly journals Biocompatibility of implants in planned and urgent hernia surgery

2021 ◽  
Vol 23 (1) ◽  
pp. 152-158
Author(s):  
B. I. Slonetskyi ◽  
M. I. Tutchenko ◽  
I. V. Verbytskyi ◽  
V. O. Kotsiubenko
Keyword(s):  
Surgical Intervention ◽  
Integrated Approach ◽  
Physicochemical Characteristics ◽  
Modern World ◽  
Hernia Surgery ◽  
Surgical Interventions ◽  
Selective Approach ◽  
Reparative Process ◽  
Clean Contaminated ◽  
Ventral Hernias

The aim of the work – to analyze modern scientific and practical achievements in the effectiveness of implants in planned and emergency hernia surgery and to identify promising areas for further research. The literature review presents modern views on the assessment of biocompatibility, effectiveness and appropriateness of the use of implants in planned and urgent hernia surgery. The importance of determining the main factors of ventral hernia occurrence, assessing the prognostic components of the reparative process course in the field of hernioplasty and methods of correction has been substantiated. Physicochemical characteristics of implants, which both historically and on an up-to-date level are used according to planned or urgent conditions for performing surgical intervention in patients with ventral hernias, are given. The necessity of using an integrated approach to choosing a method for correction or reconstruction of the abdominal wall, taking into account the biological and dynamic conditions of its state, is shown. The need for a selective approach to the choice of therapeutic tactics in patients, especially if hernia repair is necessary in conditions of a clean-contaminated or infected surgical wound, is emphasized. Conclusions. In order to improve the consequences of hernioplasty, it is necessary to assess patient's reserves and risks more thoroughly and comprehensively, as well as to make absolute indications for the use of implants. An improvement in the results of urgent and planned repair of ventral hernias is to perform surgical interventions only in surgery departments constantly provided with modern world achievements.

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