scholarly journals Pengaruh Terapi Oksigen Hiperbarik sebagai Adjuvan Radioterapi dan Kemoterapi terhadap Sel Kanker

2021 ◽  
Vol 19 (1) ◽  
pp. 132-158
Author(s):  
Windu Asmara Putra Arya Arya ◽  
Djati Widodo Edi Pratiknya ◽  
Nabil Bahasuan
Keyword(s):  
Survival Rate ◽  
Literature Review

Latar belakang : Penyakit kanker adalah jenis penyakit tidak menular yang merupakan beban dunia saat ini. Dalam mendukung pengobatan utama kanker, terapi oksigen hiperbarik dapat menjadi terapi adjuvan untuk kanker. penelitian ini bertujuan untuk mengetahui pengaruh terapi oksigen hiperbarik sebagai adjuvan radioterapi dan kemoterapi pada sel kanker. Metode : Jenis penelitian ini adalah literature review. Jurnal yang dipakai dalam penelitian ini adalah jurnal internasional yang terindeks di Scimago atau jurnal nasional yang terindeks di Sinta yang dipublikasikan pada tahun 2016 hingga tahun 2021. Waktu penelitian berlangsung dari bulan April 2021 – September 2021. Lokasi penelitian dilaksanakan di Fakultas Kedokteran Universitas Hang Tuah Surabaya. Hasil : Pada hasil penelitian terdapat 11 studi dimana 10 diantaranya menyatakan adanya pengaruh terapi oksigen hiperbarik terhadap kemoterapi dan radioterapi pada sel kanker, sementara 1 studi menyatakan tidak ada pengaruhnya. Penelitian ini juga memiliki keterbatasan, yaitu studi yang direview memiliki instumen, desain, serta dosis pemberian terapi oksigen hiperbarik yang berbeda-beda sehingga sulit untuk menyimpulkan hasil penelitian. Kesimpulan : 10 dari 11 studi pada penelitian ini menyatakan bahwa terapi oksigen hiperbarik memiliki berbagai pengaruh terhadap kemoterapi dan radioterapi pada sel kanker seperti peningkatan efikasi, sensitivitas, kerja, dan efek toksisitas dan inhibisi, serta peningkatan survival rate pada pasien kanker, sedangkan 1 studi lainnya menyatakan bahwa terapi oksigen hiperbarik tidak memiliki pengaruh apapun sebagai adjuvan terapi.

Abstract P85: Out-of-hospital Cardiac Arrests With Extracorporeal Cardiopulmonary Resuscitation In Japan: Systematic Literature Review

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Tetsuya Sakamoto ◽  
Yasufumi Asai ◽  
Ken Nagao ◽  
Yoshio Tahara ◽  
Takahiro Atsumi ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Survival Rate ◽  
Cardiopulmonary Resuscitation ◽  
Literature Review ◽  
Case Series ◽  
Extracorporeal Cardiopulmonary Resuscitation ◽  
Funnel Plot ◽  
Case Series Study ◽  
Series Study ◽  
Hospital Cardiac Arrest

Background: In Japan, extracorporeal cardiopulmonary resuscitation (ECPR) became popular for cardiac arrest patients who resist conventional advanced life supports. Regardless of many clinical experiences, there has been no previous systematic literature review. Methods: Case series, reports and proceedings of scientific meeting about ECPR for out-of-hospital cardiac arrest written in Japanese between January 1, 1983 and July 31, 2007 were collected with Japana Centra Revuo Medicina (medical publication database in Japan) and review by experts. The outcome and characteristics of the patients were investigated, and the influence of publication bias of the case series study was also examined by the Funnel Plot method. Results: There were 951 out-of-hospital cardiac arrest patients who received ECPR in 92 reports (including 59 case series and 33 case reports) during the period. The average of age was 38.1 (4 – 88) years old and 76.1% was male. Three hundreds and eighty-one cases (40.1%) were arrests of cardiac etiology, and 212 were non-cardiac (22.3%). The cause of arrest was not described in other 37.6%. Excluding reports for only one case, weighted survival rate at discharge of 792 cases those were clearly described the outcome was 39.5±10.0%. When the relationship between the number of cases and the survival rate at discharge in each 59 case series study was shown in figure by the Funnel Plot method, the plotted data presented the reverse-funnel type that centered on the average of survival rate of all. Conclusions: The influence of publication bias of previous reports in Japan was relatively low. ECPR can greatly contribute to improve the outcome of out-of hospital cardiac arrests.

scholarly journals Taxa de sucesso de restaurações com resina composta bulk-fill: Revisão de literatura / Success rate of bulk-fill composite restorations: Literature review

2019 ◽  
Vol 13 (47) ◽  
pp. 397-409
Author(s):  
Atyla Freitas Soares ◽  
Ana Clara De Sá Pinto
Keyword(s):  
Clinical Trials ◽  
Survival Rate ◽  
Literature Review ◽  
Success Rate ◽  
Composite Resin ◽  
Clinical Excellence ◽  
Google Scholar ◽  
Permanent Teeth ◽  
Deciduous Teeth ◽  
De Se

Desde a introdução das resinas compostas na Odontologia, foram evidenciadas muitas melhorias em suas propriedades. No entanto, estes materiais apresentam limitações, como a contração de polimerização, que pode resultar em fissuras de esmalte, defeito marginal, formação de fenda e microinfiltração. Para superar estas deficiências, algumas estratégias práticas incluem o uso de técnicas de inserção incremental das resinas. Porém, a mesma é demorada quando utilizada para preencher cavidades grandes e volumosas em dentes posteriores, o que tornou desejável o desenvolvimento de uma alternativa a este procedimento, e assim surgiram as resinas compostas do tipo bulk-fill, que podem ser inseridas em incrementos de 4 a 5 mm de espessura devido à sua maior translucidez. Diante deste contexto, o objetivo do presente estudo foi apresentar as taxas de sucesso das resinas bulk-fill em restaurações de dentes permanentes e decíduos, comparando ainda o resultado do seu uso em relação às resinas convencionais. A pesquisa bibliográfica foi realizada online, utilizando a ferramenta de busca Google Scholar e outras seis bases de dado eletrônicas, que são o Pubmed, Web of Sciences, National Institute for Health and Clinical Excellence, Clinical Trials–US National Institute of Health e Lilacs, sem restrição de data da publicação. Foram utilizadas as palavras-chave: “composite resin; bulk-fill composite resin; survival rate; deciduous teeth; permanent teeth”. Desta forma, foram encontrados 273 artigos que, excluindo-se os revisão de literatura, cartas ao editor e editoriais, foram reduzidos para 22 estudos a serem revisados. A lista de artigos obtida foi analisada e os artigos foram selecionados baseados nos seus títulos e resumos, de forma que foram incluídos artigos publicados em português, inglês e espanhol. Foi possível observar que há uma grande semelhança entre as resinas bulk-fill e as resinas compostas convencionais no que diz respeito às taxas de sucesso. No entanto, sugere-se que sejam realizados estudos com metodologias e amostras similares, a fim de se confirmar os resultados obtidos no presente estudo.

Role of Radiation Therapy in the Treatment of Cerebral Oligodendroglioma: An Analysis of 57 Cases and a Literature Review

Neurosurgery ◽  
1983 ◽  
Vol 13 (5) ◽  
pp. 499-503 ◽  
Author(s):  
Peter D. Reedy ◽  
Janet W. Bay ◽  
Joseph F. Hahn
Keyword(s):  
Radiation Therapy ◽  
Survival Rate ◽  
Literature Review ◽  
Cleveland Clinic ◽  
Postoperative Radiation ◽  
Postoperative Radiation Therapy

Abstract Fifty-seven cases of histologically confirmed cerebral oligodendroglioma treated at the Cleveland Clinic between 1950 and 1980 were reviewed. No difference in the 5-year survival rate was seen in patients treated with postoperative radiation therapy vs. operation alone. These data are compared to previously published series with special emphasis on the role of radiation therapy.

scholarly journals SURVIVAL OF NEW FIRMS OWNED BY NATIVES AND IMMIGRANTS IN NORWAY

2008 ◽  
Vol 13 (01) ◽  
pp. 21-38 ◽  
Author(s):  
EVGUENI VINOGRADOV ◽  
ESPEN J. ISAKSEN
Keyword(s):  
Human Capital ◽  
Survival Rate ◽  
Literature Review ◽  
Urban Areas ◽  
Relevant Literature ◽  
Survival Rates ◽  
Future Research ◽  
Business Survival ◽  
Start Up ◽  
Practical Implications

This paper investigates the survival rates of businesses founded by immigrants and natives in the context of Norway, which has not yet been explored. Based on the relevant literature review, the entrepreneur's human capital and venture's start-up characteristics were expected to explain the differences between the survival rates of businesses established by immigrants and natives. Longitudinal data on 389 firms established in 2002 were analyzed. It was revealed that the survival rate was lower for businesses established by immigrants compared to those established by natives. The analysis suggests that the relatively low survival rate of businesses established by immigrants is partly explained by the perceived novelty of the products and by the fact that immigrants are more likely to locate their businesses in urban areas. Human capital differences were not found to explain immigrant/native differences in business survival rates. Based on these results, several practical implications and suggestions for future research are offered.

scholarly journals Terapi Imunologi Pada Melanoma

2020 ◽  
Vol 8 (2) ◽  
pp. 103-110
Author(s):  
Muhamad Addin Syakir ◽  
Dwi Indria Anggraini
Keyword(s):  
Survival Rate ◽  
Literature Review ◽  
T Lymphocyte ◽  
Cytotoxic T Lymphocyte ◽  
Checkpoint Inhibitor ◽  
Interferon Α ◽  
Melanoma Metastasis ◽  
Programmed Death ◽  
Programmed Death Protein 1

Pendahulan: Imunoterapi untuk kanker digunakan berdasarkan prinsip penyakitnya bahwa sistem kekebalan tubuh mampu menghasilkan respons imun terhadap sel-sel tumor. Saat ini tatalaksana yang tersedia untuk pasien melanoma selektif berdasarkan tingkat respons dari penyakitnya. Tujuan: Untuk mengetahui tatalaksana melanoma yang menggunakan imunologi. Metode: Artikel ini disusun menggunakan metode literature review, menggunakan 32 sumber berasal dari jurnal dan buku. Hasil: Interferon-α telah disetujui untuk pengobatan ajuvan stadium III melanoma dengan peningkatan survival rate. Diperlukan pendekatan baru dan lebih inovatif dengan peningkatan efek terapi. Prognosis pasien dengan melanoma metastasis di dunia telah berubah secara dramatis sejak adanya imun checkpoint inhibitor. Pembahasan: Ipilimumab, yang menargetkan protein cytotoxic T lymphocyte-associated protein 4 (CTLA-4) adalah agen pertama yang ada. Selanjutnya nivolumab dan pembrolizumab yang berikatan dengan protein programmed death protein 1 (PD-1) telah terbukti lebih efektif dan lebih rendah angka toksisitasnya daripada ipilimumab. Kombinasi nivolumab atau pembrolizumab dengan ipilimumab telah menghasilkan peningkatan tingkat respons dan hasil survival rate pasien. Tinjauan pustaka ini akan mengeksplorasi data uji klinis penting yang telah menyebabkan penggunaan agen imunoterapi ini di dunia dan beberapa hasil uji klinis yang saat ini dilaporkan untuk terapi kombinasi baru. Simpulan: Saat ini terapi imunologi untuk tatalaksana melanoma dapat di terapkan.   Kata kunci: Imunoterapi, kemoterapi, melanoma, tatalaksana

scholarly journals Immune Myocarditis Overlapping With Myasthenia Gravis Due to Anti-PD-1 Treatment for a Chordoma Patient: A Case Report and Literature Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Shujing Liang ◽  
Jingxian Yang ◽  
Yun Lin ◽  
Tong Li ◽  
Wenrong Zhao ◽  
...  
Keyword(s):  
Case Report ◽  
Survival Rate ◽  
Side Effects ◽  
Literature Review ◽  
Best Practices ◽  
Adverse Events ◽  
Myasthenia Gravis ◽  
Effective Treatment ◽  
Malignant Tumor ◽  
Clinical Benefit

Immunotherapy begins to be widely used due to the increasing exploration and gratifying effects in multiple cancers. Chordoma, as a rare bone malignant tumor, often recurs and metastasizes after undergoing surgery and radiotherapy. Therefore, immunotherapy can be explored as an emerging, potentially effective treatment to improve the survival rate and clinical benefit of patients. However, a variety of immune-related adverse events (irAEs) cannot be avoided completely. And the immunotherapy-induced myocarditis, as a rare but fatal irAE, has been increasingly reported. Understanding the mechanism involved in irAEs can inform best practices for side effects management. Here, we firstly reported a case of immune myocarditis and subsequent myasthenia gravis (MG) following anti-PD-1 treatment for chordoma.

scholarly journals Orthodontic Extrusion vs. Surgical Extrusion to Rehabilitate Severely Damaged Teeth: A Literature Review

2021 ◽  
Vol 18 (18) ◽  
pp. 9530
Author(s):  
Martina Cordaro ◽  
Edoardo Staderini ◽  
Ferruccio Torsello ◽  
Nicola Maria Grande ◽  
Matteo Turchi ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Survival Rate ◽  
Literature Review ◽  
Dental Implant ◽  
Tooth Extraction ◽  
Treatment Choice ◽  
Invasive Technique ◽  
Orthodontic Extrusion ◽  
Tissue Attachment ◽  
Crown Lengthening

The need to rehabilitate severely compromised teeth is frequent in daily clinical practice. Tooth extraction and replacement with dental implant represents a common treatment choice. However, the survival rate for implants is inferior to teeth, even if severely damaged but properly treated. In order to reestablish a physiological supracrestal tissue attachment of damaged teeth and to arrange an efficient ferrule effect, three options can be considered: crown lengthening, orthodontic extrusion and surgical extrusion. Crown lengthening is considered an invasive technique that causes the removal of part of the bony support, while both orthodontic and surgical extrusion can avoid this inconvenience and can be used successfully in the treatment of severely damaged teeth. The aim of the present narrative review is to compare advantages, disadvantages, time of therapy required, contraindications and complications of both techniques.

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