scholarly journals Wireless Wearable Electrochemical Sensors: A Review

2021 ◽  
Vol 8 (10Years) ◽  
Author(s):  
Thais Alves ◽  
Patricia Deroco ◽  
Dagwin Wachholz Junior ◽  
Lourenço Vidotto ◽  
Lauro Kubota

The demand for wearable sensors has been grown rapidly over the past few years, mainly those related to monitor health, fitness and their surroundings. Consequently, wearable chemical sensing has become a crucial appliance area for wireless sensors and has proved to be a very challenging and multidisciplinary area. The great advantage of coupling wireless communication to different types of wearable sensors is the enhancement of the sensor’s scope for remote and resource-limited settings with the possibility of obtaining real-time data acquisition and application in different areas like homeland defense, home-based healthcare, and food logistics. Being the electrochemical sensors considered attractive and promising to use in the wireless chemical sensor field, due to its features such as simple structure, the possibility of miniaturization, comfort, simplicity of operation, high sensitivity, fast response, relatively low energy consumption and low manufacturing cost. Furthermore, wearable electrochemical sensors enable obtaining insights into individuals' health status through the noninvasive monitoring of clinically relevant biomarkers in different biofluids without complex sampling, manipulation and treatment steps. In this review, we present the main advances in technologies used in the development of fully integrated wireless wearable electrochemical devices, such as communication protocols, data collection and privacy concerns and power sources. We also discuss in a critical way the main challenges, trends, strategies and new technologies that will drive this research line in the future. Lastly, we highlight the progress in the last few years in healthcare, sports, security and defense, and forensic applications.

2015 ◽  
Vol 7 (283) ◽  
pp. 283rv3-283rv3 ◽  
Author(s):  
Steven R. Steinhubl ◽  
Evan D. Muse ◽  
Eric J. Topol

The surge in computing power and mobile connectivity have fashioned a foundation for mobile health (mHealth) technologies that can transform the mode and quality of clinical research and health care on a global scale. Unimpeded by geographical boundaries, smartphone-linked wearable sensors, point-of-need diagnostic devices, and medical-grade imaging, all built around real-time data streams and supported by automated clinical decision–support tools, will enable care and enhance our understanding of physiological variability. However, the path to mHealth incorporation into clinical care is fraught with challenges. We currently lack high-quality evidence that supports the adoption of many new technologies and have financial, regulatory, and security hurdles to overcome. Fortunately, sweeping efforts are under way to establish the true capabilities and value of the evolving mHealth field.


Author(s):  
Jonas Flueckiger ◽  
Frank K. Ko ◽  
Karen C. Cheung

We present the fabrication of a polymer blend PANi/PEO nanofiber based sensor as well as a metal oxide TiO2 nanofiber based sensor. Electrospinning was used for the fabrication of the electroactive nanofibers. The conductivity of those fibers is highly sensitive to the chemical environment and is modified through the adsorption of different species. Used as a chemiresistor the nanofibers offer a higher sensitivity than thin films due to the increased surface to volume ratio. Impedance spectroscopy was used for electrical characterization of the fibers showing high sensitivity. Preliminary measurements of the sensors dynamic response when exposed to alternating chemical environments showed fast response times and good signal stability.


2019 ◽  
Author(s):  
Alessandro Mascheroni ◽  
Eun Kyoung Choe ◽  
Yuhan Luo ◽  
Michele Marazza ◽  
Clara Ferlito ◽  
...  

BACKGROUND Home-based systems for ecological momentary assessment of clinically-relevant information in Parkinson’s Disease (PD) are helpful tools to improve patients’ care. Nevertheless, new technologies are not always easy-to-use for these patients. OBJECTIVE We developed a tablet-based application, SleepFit, specifically designed for patients with PD, to collect objective and subjective data at their home. SleepFit is presented with the improvements made from the prototype to the latest v2.0 version, aimed to enhance user-friendliness and the quality of the collected data. METHODS The core structure of SleepFit consists of: a) an electronic finger-tapping test; b) motor, sleepiness, and emotional subjective scales; c) a sleep diary. SleepFit v2.0 features enhanced ergonomics and graphics; automated flows that guide the patients in performing tasks throughout the 24 hours; secured real-time data collection and consultation; the possibility to easily integrate new tasks and features. Fifty-six patients with PD were asked to perform multiple home-assessments four times a day for two weeks. Patients’ compliance to SleepFit was calculated as the proportion of completed tasks out of the total number of expected tasks; satisfaction was evaluated as a potential willingness to use SleepFit again after the end of the study. RESULTS Fifty-two patients were included in the analyses. Overall compliance (all versions) was 88.9%. SleepFit was progressively enhanced and compliance increased from 87.9% to 89.9%. Among the patients who used the final version, 96.2% declared they would use SleepFit again. CONCLUSIONS SleepFit is an easy-to-use tablet-application to prospectively collect objective and subjective clinical data and to increase compliance in home-based studies in PD


Crystals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 648
Author(s):  
Aijie Liang ◽  
Jingyuan Ming ◽  
Wenguo Zhu ◽  
Heyuan Guan ◽  
Xinyang Han ◽  
...  

Breath monitoring is significant in assessing human body conditions, such as cardiac and pulmonary symptoms. Optical fiber-based sensors have attracted much attention since they are immune to electromagnetic radiation, thus are safe for patients. Here, a microfiber (MF) humidity sensor is fabricated by coating tin disulfide (SnS2) nanosheets onto the surface of MF. The small diameter (~8 μm) and the long length (~5 mm) of the MF promise strong interaction between guiding light and SnS2. Thus, a small variation in the relative humidity (RH) will lead to a large change in optical transmitted power. A high RH sensitivity of 0.57 dB/%RH is therefore achieved. The response and recovery times are estimated to be 0.08 and 0.28 s, respectively. The high sensitivity and fast response speed enable our SnS2-MF sensor to monitor human breath in real time.


Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1104
Author(s):  
Shin-Yan Chiou ◽  
Kun-Ju Lin ◽  
Ya-Xin Dong

Positron emission tomography (PET) is one of the commonly used scanning techniques. Medical staff manually calculate the estimated scan time for each PET device. However, the number of PET scanning devices is small, the number of patients is large, and there are many changes including rescanning requirements, which makes it very error-prone, puts pressure on staff, and causes trouble for patients and their families. Although previous studies proposed algorithms for specific inspections, there is currently no research on improving the PET process. This paper proposes a real-time automatic scheduling and control system for PET patients with wearable sensors. The system can automatically schedule, estimate and instantly update the time of various tasks, and automatically allocate beds and announce schedule information in real time. We implemented this system, collected time data of 200 actual patients, and put these data into the implementation program for simulation and comparison. The average time difference between manual and automatic scheduling was 7.32 min, and it could reduce the average examination time of 82% of patients by 6.14 ± 4.61 min. This convinces us the system is correct and can improve time efficiency, while avoiding human error and staff pressure, and avoiding trouble for patients and their families.


Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1915
Author(s):  
Shenawar Ali Khan ◽  
Muhammad Saqib ◽  
Muhammad Muqeet Rehman ◽  
Hafiz Mohammad Mutee Ur Rehman ◽  
Sheik Abdur Rahman ◽  
...  

A novel composite based on a polymer (P(VDF-TrFE)) and a two-dimensional material (graphene flower) was proposed as the active layer of an interdigitated electrode (IDEs) based humidity sensor. Silver (Ag) IDEs were screen printed on a flexible polyethylene terephthalate (PET) substrate followed by spin coating the active layer of P(VDF-TrFE)/graphene flower on its surface. It was observed that this sensor responds to a wide relative humidity range (RH%) of 8–98% with a fast response and recovery time of 0.8 s and 2.5 s for the capacitance, respectively. The fabricated sensor displayed an inversely proportional response between capacitance and RH%, while a directly proportional relationship was observed between its impedance and RH%. P(VDF-TrFE)/graphene flower-based flexible humidity sensor exhibited high sensitivity with an average change of capacitance as 0.0558 pF/RH%. Stability of obtained results was monitored for two weeks without any considerable change in the original values, signifying its high reliability. Various chemical, morphological, and electrical characterizations were performed to comprehensively study the humidity-sensing behavior of this advanced composite. The fabricated sensor was successfully used for the applications of health monitoring and measuring the water content in the environment.


2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Jung Joon Lee ◽  
Srinivas Gandla ◽  
Byeongjae Lim ◽  
Sunju Kang ◽  
Sunyoung Kim ◽  
...  

Abstract Conformal and ultrathin coating of highly conductive PEDOT:PSS on hydrophobic uneven surfaces is essential for resistive-based pressure sensor applications. For this purpose, a water-based poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) solution was successfully exchanged to an organic solvent-based PEDOT:PSS solution without any aggregation or reduction in conductivity using the ultrafiltration method. Among various solvents, the ethanol (EtOH) solvent-exchanged PEDOT:PSS solution exhibited a contact angle of 34.67°, which is much lower than the value of 96.94° for the water-based PEDOT:PSS solution. The optimized EtOH-based PEDOT:PSS solution exhibited conformal and uniform coating, with ultrathin nanocoated films obtained on a hydrophobic pyramid polydimethylsiloxane (PDMS) surface. The fabricated pressure sensor showed high performances, such as high sensitivity (−21 kPa−1 in the low pressure regime up to 100 Pa), mechanical stability (over 10,000 cycles without any failure or cracks) and a fast response time (90 ms). Finally, the proposed pressure sensor was successfully demonstrated as a human blood pulse rate sensor and a spatial pressure sensor array for practical applications. The solvent exchange process using ultrafiltration for these applications can be utilized as a universal technique for improving the coating property (wettability) of conducting polymers as well as various other materials.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Zhuang Hui ◽  
Ming Xiao ◽  
Daozhi Shen ◽  
Jiayun Feng ◽  
Peng Peng ◽  
...  

Abstract With the increase in the use of electronic devices in many different environments, a need has arisen for an easily implemented method for the rapid, sensitive detection of liquids in the vicinity of electronic components. In this work, a high-performance power generator that combines carbon nanoparticles and TiO2 nanowires has been fabricated by sequential electrophoretic deposition (EPD). The open-circuit voltage and short-circuit current of a single generator are found to exceed 0.7 V and 100 μA when 6 μL of water was applied. The generator is also found to have a stable and reproducible response to other liquids. An output voltage of 0.3 V was obtained after 244, 876, 931, and 184 μs, on exposure of the generator to 6 μL of water, ethanol, acetone, and methanol, respectively. The fast response time and high sensitivity to liquids show that the device has great potential for the detection of small quantities of liquid. In addition, the simple easily implemented sequential EPD method ensures the high mechanical strength of the device. This compact, reliable device provides a new method for the sensitive, rapid detection of extraneous liquids before they can impact the performance of electronic circuits, particularly those on printed circuit board.


2016 ◽  
Vol 680 ◽  
pp. 208-211
Author(s):  
Lian Lian Wu ◽  
Qiang Li ◽  
Dan Yu Jiang ◽  
Jin Feng Xia

In this paper, La0.65Sr0.35MnO3 (LSM) oxide powder with ultrafine structure has been synthesized by self-propagating combustion method. The powders were characterized by X-ray diffraction, scanning electron microscopy and laser size analysis. Compared to the powders prepared by traditional solid-phase method, the grain size of powders prepared by self-propagating combustion method is relatively small and uniform. Starting from ultrafine LSM powders, sensing electrode (SE) for NO2 mixed-potential sensors based on yttria-stablized zirconia (YSZ) was fabricated. As-obtained NO2 sensor displays fast response and high sensitivity (25.4mV/decade). The response values of the sensor have good linear relationship with the logarithm of NO2 concentration varying from 30ppm to 500ppm.Keywords:Self-propagating combustion method; La0.65Sr0.35MnO3; NOx sensor; YSZ


2007 ◽  
Vol 12 (5) ◽  
pp. 656-667 ◽  
Author(s):  
Michael P. Maher ◽  
Nyan-Tsz Wu ◽  
Hong Ao

Many high-throughput ion channel assays require the use of voltage-sensitive dyes to detect channel activity in the presence of test compounds. Dye systems employing Förster resonance energy transfer (FRET) between 2 membrane-bound dyes are advantageous in combining high sensitivity, relatively fast response, and ratiometric output. The most widely used FRET voltage dye system employs a coumarin fluorescence donor whose excitation spectrum is pH dependent. The authors have validated a new class of voltage-sensitive FRET donors based on a pyrene moiety. These dyes are significantly brighter than CC2-DMPE and are not pH sensitive in the physiological range. With the new dye system, the authors demonstrate a new high-throughput assay for the acid-sensing ion channel (ASIC) family. They also introduce a novel method for absolute calibration of voltage-sensitive dyes, simultaneously determining the resting membrane potential of a cell. ( Journal of Biomolecular Screening 2007:656-667)


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