Refined Calculation Assessment of Failure and Fault Tolerance of Sensitive Electronic Components with Actual Mass Protection

2021 ◽  
Vol 8 (4) ◽  
pp. 77-85
Author(s):  
S. V. Golovanov ◽  
◽  
A. A. Meshcheryakov ◽  
V. Yu. Murzin ◽  
P. B. Lagov ◽  
...  
Keyword(s):  
Fault Tolerance ◽  
Large Scale ◽  
Three Dimensional ◽  
High Energy ◽  
Electronic Components ◽  
Heavy Charged Particles ◽  
Average Mass ◽  
The Impact ◽  
Onboard Equipment ◽  
Actual Mass

Nowadays rocket and space industry enterprises use a simplified method to evaluate failure and fault tolerance of the onboard equipment to single event effects (SEEs), when the calculation is performed for the minimum mass protection thickness (g/cm2 ) of potentially sensitive electronic components determined, as a rule, by the minimum wall thickness of the device under consideration. In this case, all structural elements of the onboard equipment, spacecraft, and neighboring devices are not included, which, in many cases, leads to a significant overestimation of the calculated SEEs frequency especially for large scale integration ICs. Neglecting the actual mass protection may require redundant measures to ensure failure and fault tolerance. The work proposes an improved approach of calculating failure and fault tolerance of sensitive electronic components and onboard equipment to the impact of heavy charged particles and high-energy protons that causes SEEs, which consists in using programs for calculating absorbed doses by the sectorization method in three-dimensional models, which makes possible to determine the minimum, maximum, and average mass protection of electronic components with the complete design of the onboard equipment and spacecraft.

scholarly journals 3DIV update for 2021: a comprehensive resource of 3D genome and 3D cancer genome

2020 ◽  
Vol 49 (D1) ◽  
pp. D38-D46
Author(s):  
Kyukwang Kim ◽  
Insu Jang ◽  
Mooyoung Kim ◽  
Jinhyuk Choi ◽  
Min-Seo Kim ◽  
...  
Keyword(s):  
Cell Line ◽  
Large Scale ◽  
Three Dimensional ◽  
Cancer Cell Line ◽  
Cancer Genome ◽  
Structural Variations ◽  
3D Genome ◽  
Tightly Coupled ◽  
Regulatory Effects ◽  
The Impact

Abstract Three-dimensional (3D) genome organization is tightly coupled with gene regulation in various biological processes and diseases. In cancer, various types of large-scale genomic rearrangements can disrupt the 3D genome, leading to oncogenic gene expression. However, unraveling the pathogenicity of the 3D cancer genome remains a challenge since closer examinations have been greatly limited due to the lack of appropriate tools specialized for disorganized higher-order chromatin structure. Here, we updated a 3D-genome Interaction Viewer and database named 3DIV by uniformly processing ∼230 billion raw Hi-C reads to expand our contents to the 3D cancer genome. The updates of 3DIV are listed as follows: (i) the collection of 401 samples including 220 cancer cell line/tumor Hi-C data, 153 normal cell line/tissue Hi-C data, and 28 promoter capture Hi-C data, (ii) the live interactive manipulation of the 3D cancer genome to simulate the impact of structural variations and (iii) the reconstruction of Hi-C contact maps by user-defined chromosome order to investigate the 3D genome of the complex genomic rearrangement. In summary, the updated 3DIV will be the most comprehensive resource to explore the gene regulatory effects of both the normal and cancer 3D genome. ‘3DIV’ is freely available at http://3div.kr.

scholarly journals The Impact of China’s Low-Carbon Initiative on the Location Expansion of International SPA Enterprises

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Zhaoyang Zhao ◽  
Chong Ye
Keyword(s):  
Economic Development ◽  
Product Life Cycle ◽  
Large Scale ◽  
High Energy ◽  
Inhibitory Effect ◽  
Low Carbon ◽  
Suppression Effect ◽  
Carbon Neutrality ◽  
The Difference ◽  
The Impact

“Fast fashion” represents a short product life cycle, and international SPA enterprises are therefore criticised as representatives of high energy consumption, pollution, and emissions, which is contrary to China’s goal of achieving carbon neutrality. In the context of China’s shift to a low-carbon economic development model, how should SPA enterprises breakthrough in the face of China’s large-scale market advantage and domestic demand potential? Based on the statistics of 277 prefecture-level cities from 2010 to 2018, this article selects 5 leading international SPA enterprises and uses the difference-in-differences (DID) method to explore the impact of low-carbon initiative on the location expansion of international SPA enterprises. The results suggest that the quantity of location expansions of SPA enterprises in the pilot cities is significantly lower by approximately 0.418 units compared with the nonpilot cities, implying that the low-carbon initiative has a significant inhibitory effect on the location expansion of SPA enterprises. After a series of robustness tests, the conclusion is valid. The results of the heterogeneity test suggest that the suppression effect is mainly found in the subsample of central cities and cities with medium and low levels of economic development. This article proposes that SPA enterprises should reduce their carbon emissions and gradually explore a green and sustainable development path.

scholarly journals Superior Pseudocapacitive Storage of a Novel Ni3Si2/NiOOH/Graphene Nanostructure for an All-Solid-State Supercapacitor

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Jing Ning ◽  
Maoyang Xia ◽  
Dong Wang ◽  
Xin Feng ◽  
Hong Zhou ◽  
...  
Keyword(s):  
Solid State ◽  
High Performance ◽  
Large Scale ◽  
Specific Capacity ◽  
Three Dimensional ◽  
Chemical Vapor ◽  
Specific Area ◽  
High Energy ◽  
Scale Production ◽  
Free Standing

Abstract Recent developments in the synthesis of graphene-based structures focus on continuous improvement of porous nanostructures, doping of thin films, and mechanisms for the construction of three-dimensional architectures. Herein, we synthesize creeper-like Ni3Si2/NiOOH/graphene nanostructures via low-pressure all-solid melting-reconstruction chemical vapor deposition. In a carbon-rich atmosphere, high-energy atoms bombard the Ni and Si surface, and reduce the free energy in the thermodynamic equilibrium of solid Ni–Si particles, considerably catalyzing the growth of Ni–Si nanocrystals. By controlling the carbon source content, a Ni3Si2 single crystal with high crystallinity and good homogeneity is stably synthesized. Electrochemical measurements indicate that the nanostructures exhibit an ultrahigh specific capacity of 835.3 C g−1 (1193.28 F g−1) at 1 A g−1; when integrated as an all-solid-state supercapacitor, it provides a remarkable energy density as high as 25.9 Wh kg−1 at 750 W kg−1, which can be attributed to the free-standing Ni3Si2/graphene skeleton providing a large specific area and NiOOH inhibits insulation on the electrode surface in an alkaline solution, thereby accelerating the electron exchange rate. The growth of the high-performance composite nanostructure is simple and controllable, enabling the large-scale production and application of microenergy storage devices.

Can the Deforestation Breeze Change the Rainfall in Amazonia? A Case Study for the BR-163 Highway Region

2010 ◽  
Vol 14 (18) ◽  
pp. 1-25 ◽  
Author(s):  
Sandra I. Saad ◽  
Humberto R. da Rocha ◽  
Maria A. F. Silva Dias ◽  
Rafael Rosolem
Keyword(s):  
Boundary Layer ◽  
Large Scale ◽  
Three Dimensional ◽  
Atmospheric Modeling ◽  
Thermal Cell ◽  
Soil Wetness ◽  
Soil Dryness ◽  
Regional Atmospheric Modeling ◽  
The Impact

Abstract The authors simulated the effects of Amazonian mesoscale deforestation in the boundary layer and in rainfall with the Brazilian Regional Atmospheric Modeling System (BRAMS) model. They found that both the area and shape (with respect to wind incidence) of deforestation and the soil moisture status contributed to the state of the atmosphere during the time scale of several weeks, with distinguishable patterns of temperature, humidity, and rainfall. Deforestation resulted in the development of a three-dimensional thermal cell, the so-called deforestation breeze, slightly shifted downwind to large-scale circulation. The boundary layer was warmer and drier above 1000-m height and was slightly wetter up to 2000-m height. Soil wetness affected the circulation energetics proportionally to the soil dryness (for soil wetness below ∼0.6). The shape of the deforestation controlled the impact on rainfall. The horizontal strips lined up with the prevailing wind showed a dominant increase in rainfall, significant up to about 60 000 km2. On the other hand, in the patches aligned in the opposite direction (north–south), there was both increase and decrease in precipitation in two distinct regions, as a result of clearly separated upward and downward branches, which caused the precipitation to increase for patches up to 15 000 km2. The authors’ estimates for the size of deforestation impacting the rainfall contributed to fill up the low spatial resolution in other previous studies.

An Impact Assessment of GPS Radio Occultation Data on Prediction of a Rapidly Developing Cyclone over the Southern Ocean*

2014 ◽  
Vol 142 (11) ◽  
pp. 4187-4206 ◽  
Author(s):  
Shu-Ya Chen ◽  
Tae-Kwon Wee ◽  
Ying-Hwa Kuo ◽  
David H. Bromwich
Keyword(s):  
Data Assimilation ◽  
Southern Ocean ◽  
Large Scale ◽  
Radio Occultation ◽  
Three Dimensional ◽  
Wrf Model ◽  
The Other ◽  
Gps Radio Occultation ◽  
The Antarctic ◽  
The Impact

Abstract The impact of global positioning system (GPS) radio occultation (RO) data on an intense synoptic-scale storm that occurred over the Southern Ocean in December 2007 is evaluated, and a synoptic explanation of the assessed impact is offered. The impact is assessed by using the three-dimensional variational data assimilation scheme (3DVAR) of the Weather Research and Forecasting (WRF) Model Data Assimilation system (WRFDA), and by comparing two experiments: one with and the other without assimilating the refractivity data from four different RO missions. Verifications indicate significant positive impacts of the RO data in various measures and parameters as well as in the track and intensity of the Antarctic cyclone. The analysis of the atmospheric processes underlying the impact shows that the assimilation of the RO data yields substantial improvements in the large-scale circulations that in turn control the development of the Antarctic storm. For instance, the RO data enhanced the strength of a 500-hPa trough over the Southern Ocean and prevented the katabatic flow near the coast of East Antarctica from an overintensification. This greatly influenced two low pressure systems of a comparable intensity, which later merged together and evolved into the major storm. The dominance of one low over the other in the merger dramatically changed the track, intensity, and structure of the merged storm. The assimilation of GPS RO data swapped the dominant low, leading to a remarkable improvement in the subsequent storm’s prediction.

scholarly journals Using AlphaFold to predict the impact of single mutations on protein stability and function

2021 ◽  
Author(s):  
Marina A Pak ◽  
Karina A Markhieva ◽  
Mariia S Novikova ◽  
Dmitry S Petrov ◽  
Ilya S Vorobyev ◽  
...  
Keyword(s):  
Protein Folding ◽  
Protein Stability ◽  
Structure Prediction ◽  
Large Scale ◽  
3D Structure ◽  
Three Dimensional ◽  
Single Mutation ◽  
Before And After ◽  
And Function ◽  
The Impact

AlphaFold changed the field of structural biology by achieving three-dimensional (3D) structure prediction from protein sequence at experimental quality. The astounding success even led to claims that the protein folding problem is "solved". However, protein folding problem is more than just structure prediction from sequence. Presently, it is unknown if the AlphaFold-triggered revolution could help to solve other problems related to protein folding. Here we assay the ability of AlphaFold to predict the impact of single mutations on protein stability (ΔΔG) and function. To study the question we extracted metrics from AlphaFold predictions before and after single mutation in a protein and correlated the predicted change with the experimentally known ΔΔG values. Additionally, we correlated the AlphaFold predictions on the impact of a single mutation on structure with a large scale dataset of single mutations in GFP with the experimentally assayed levels of fluorescence. We found a very weak or no correlation between AlphaFold output metrics and change of protein stability or fluorescence. Our results imply that AlphaFold cannot be immediately applied to other problems or applications in protein folding.

Effect of Component Layout and Geometry on the Flow Distribution in Electronics Circuit Packs

1991 ◽  
Vol 113 (1) ◽  
pp. 50-57 ◽  
Author(s):  
K. Azar ◽  
E. T. Russell
Keyword(s):  
Experimental Investigation ◽  
Three Dimensional ◽  
Flow Distribution ◽  
Reynolds Numbers ◽  
Water Tunnel ◽  
Large Aspect Ratio ◽  
Electronic Components ◽  
Component Layout ◽  
Multiple Component ◽  
The Impact

An experimental investigation was conducted to study the impact of component layout and geometry on flow distribution on a circuit pack. The experiment was conducted in a water tunnel using aluminum blocks to simulate various electronic components. The experiments were conducted for laminar and onset of transition Reynolds numbers. Diluted ink was used as the flow visualization vehicle. The study looked at flow over single component, multiple component, and fully loaded circuit packs. The study drew a number of conclusions including the flows were highly three dimensional, and location and orientation of components with large aspect ratio will significantly affect circuit pack flow distribution.

Large-scale fabrication of BCN nanotube architecture entangled on a three-dimensional carbon skeleton for energy storage

2018 ◽  
Vol 6 (42) ◽  
pp. 21225-21230 ◽  
Author(s):  
Hassina Tabassum ◽  
Chong Qu ◽  
Kunting Cai ◽  
Waseem Aftab ◽  
Zibin Liang ◽  
...  
Keyword(s):  
Energy Storage ◽  
Power Density ◽  
Large Scale ◽  
Three Dimensional ◽  
High Energy ◽  
Carbon Skeleton ◽  
Nitrogen Doped ◽  
Nitrogen Doped Carbon ◽  
Energy And Power Density ◽  
Melamine Foam

The BCN nanotubes have been fabricated on melamine foam (MF) derived three dimensional (3D) nitrogen doped carbon skeleton, which exhibited high energy and power density for the SSC and ASC devices.

scholarly journals Smart-Grid-Aware Load Regulation of Multiple Datacenters towards the Variable Generation of Renewable Energy

2019 ◽  
Vol 9 (3) ◽  
pp. 518 ◽  
Author(s):  
Peicong Luo ◽  
Xiaoying Wang ◽  
Hailong Jin ◽  
Yuling Li ◽  
Xuejiao Yang
Keyword(s):  
Renewable Energy ◽  
Smart Grid ◽  
Energy Input ◽  
Large Scale ◽  
Weather Conditions ◽  
Clean Energy ◽  
High Energy ◽  
Stochastic Algorithm ◽  
Power Sources ◽  
The Impact

Recently, as renewable and distributed power sources boost, many such resources are integrated into the smart grid as a clean energy input. However, since the generation of renewable energy is intermittent and unstable, the smart grid needs to regulate the load to maintain stability after integrating the renewable energy source. At the same time, with the development of cloud computing, large-scale datacenters are becoming potentially controllable loads for the smart grid due to their high energy consumption. In this paper, we propose an appropriate approach to dynamically adjust the datacenter load to balance the unstable renewable energy input into the grid. This could meet the demand response requirements by taking advantage of the variable power consumption of datacenters. We have examined the scenarios of one or more datacenters being integrated into the grid and adopted a stochastic algorithm to solve the problem we established. The experimental results illustrated that the dynamic load management of multiple datacenters could help the smart grid to reduce losses and thus save operational costs. Besides, we also analyzed the impact of the flexibility and the delay of datacenter actions, which could be applied to more general scenarios in realistic environments. Furthermore, considering the impact of the action delay, we employed a forecasting method to predict renewable energy generation in advance to eliminate the extra losses brought by the delay as much as possible. By predicting solar power generation, the improved results showed that the proposed method was effective and feasible under both sunny and cloudy/rainy/snowy weather conditions.

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