Psychedelics and Mindfulness: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Chelsea Radakovic ◽  
Ratko Radakovic ◽  
Guy Peryer ◽  
Jo-Anne Geere
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Grey Literature ◽  
Inner Experience ◽  
Administration Method ◽  
Acting With Awareness ◽  
Mindfulness Facets ◽  
General Populations ◽  
Clinical Conditions ◽  
The Relationship

Rationale: The benefits of mindfulness are well documented and it has become widely used in both clinical and general populations. The benefits of classic serotonergic psychedelics (e.g. psilocybin, LSD, DMT, ayahuasca) are becoming more widely known with the resurgence in research in the past decade. Research has suggested a link between psychedelics and an increase in mindfulness with lasting effect, but no systematic review has examined specifics aspects of this increase in mindfulness. Objective: Explore the link between psychedelics and characteristics of mindfulness. Methods: We conducted a systematic search across multiple databases, inclusive of grey literature and backwards/forward-citation tracking, on the 18 January 2021. The search strategy included terms relating to mindfulness and psychedelics, with no restriction on clinical or non-clinical conditions. Study quality was assessed. An exploratory random-effects meta-analysis was conducted on pre-post mindfulness data relative to psychedelic ingestion. Results: Of 1805 studies screened, 13 were included in the systematic review. There was substantial variability in participant characteristics, psychedelic administration method and measurement of mindfulness. The ingestion of psychedelics is associated with an increase in mindfulness, specifically relating to domains of acceptance, which encompasses non-judgement of inner experience and non-reactivity. The meta-analysis of a subset of studies (N=6) showed small effects overall relative to ayahuasca ingestion, increasing mindfulness facets of non-judgement of inner experience and non-reactivity, as well as acting with awareness. Conclusions: Further methodologically robust research is needed to elucidate the relationship between psychedelics and mindfulness. However, mindfulness and specific facets relating to acceptance have been shown to increase following ingestion of psychedelics in a number of studies.

scholarly journals Testing the Intermediary Role of Perceived Stress in the Relationship between Mindfulness and Burnout Subtypes in a Large Sample of Spanish University Students

2020 ◽  
Vol 17 (19) ◽  
pp. 7013
Author(s):  
David Martínez-Rubio ◽  
Juan P. Sanabria-Mazo ◽  
Albert Feliu-Soler ◽  
Ariadna Colomer-Carbonell ◽  
Cristina Martínez-Brotóns ◽  
...  
Keyword(s):  
Perceived Stress ◽  
Structural Equation ◽  
Cross Sectional Study ◽  
Burnout Syndrome ◽  
Inner Experience ◽  
Cross Sectional ◽  
Acting With Awareness ◽  
Mindfulness Facets ◽  
The Relationship ◽  
Burnout Subtypes

The burnout syndrome is the consequence of chronic stress that overwhelms an individual’s resources to cope with occupational or academic demands. Frenetic, under-challenged, and worn-out are different burnout subtypes. Mindfulness has been recognized to reduce stress, comprising five facets (observing, describing, acting with awareness, non-judging of inner experience, and non-reactivity to inner experience). This cross-sectional study aimed to assess the relationship between mindfulness facets, perceived stress, and burnout subtypes in a sample of 1233 students of Education, Nursing, and Psychology degrees from different universities of Valencia (Spain). Structural Equation Modelling (SEM) was computed showing an adequate fit (Chi-square, CFI, TLI, RMSEA, and SRMR). Four mindfulness facets (all but observing) significantly correlated with general second-order mindfulness. Unexpected results were found: Acting with awareness facet was positively associated with frenetic subtype, while the non-reacting facet was positively associated with frenetic and under-challenged subtype. Ultimately, mindfulness facets negatively predicted the perceived stress levels, which in turn, predicted burnout. However, mindfulness plays different roles in the early stages of burnout syndrome (i.e., frenetic and under-challenged).

scholarly journals Participation of endotoxin in root canal infections: A systematic review and meta-analysis

2017 ◽  
Vol 11 (03) ◽  
pp. 398-406 ◽  
Author(s):  
Frederico Canato Martinho ◽  
Diego Guilherme Dias de Rabello ◽  
Luciana Louzada Ferreira ◽  
Gustavo Giacomelli Nascimento
Keyword(s):  
Systematic Review ◽  
Root Canal ◽  
Meta Analysis ◽  
Grey Literature ◽  
Clinical Signs ◽  
Cochrane Library ◽  
Radiographic Features ◽  
Endodontic Infection ◽  
Meta Analyses ◽  
The Relationship

ABSTRACTThis systematic review and meta-analysis aimed to evaluate the relationship between endotoxin levels and presence of clinical signs/symptoms and radiographic features in patients with endodontic infection. Electronic searches were performed on Medline/PubMed, Embase, Cochrane Library, Scielo, Science Direct, Web of Knowledge and Scopus databases for identification of relevant studies published up to December 2016. Grey literature was searched in Google Scholar. The selected literature was reviewed independently by two authors. Clinical studies evaluating the levels of endotoxin and the presence of clinical and radiographic features were included in this review. In order to determine the relationship between endotoxin levels and presence of clinical signs/symptoms and radiographic features meta-analyses were performed. Among the 385 articles identified in the initial search, 30 were included for full-text appraisal and only eight studies met the inclusion criteria for this systematic review. Meta-analysis revealed that individuals having teeth with tenderness to percussion (TTP) (P = 0.04; I2 57%) and previous episode of pain (PEP) (P = 0.001; I2 81%) had higher levels of endotoxin than their counterparts. Size of radiographic lesion >2 mm (P = 0.02; I2 68%) and presence of root canal exudation (EX) (P = 0.0007; I2 0%) were associated with higher levels of endotoxin. This systematic review and meta-analyses provided a strong evidence that endotoxin are related with the presence of clinical signs/symptoms and radiographic features in patients with endodontic infection.

scholarly journals M71. THE INFLUENCE OF METACOGNITIVE CAPACITIES ON SPECIFIC NEGATIVE SYMPTOMS: A SYSTEMATIC REVIEW AND INDIVIDUAL PARTICIPANT META-ANALYSIS OF INTERVIEW-BASED DATA

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S162-S163
Author(s):  
Nicola McGuire ◽  
Andrew Gumley ◽  
Ilanit Hasson-Ohayon ◽  
Warut Aunjitsakul ◽  
Orkun Aydin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Negative Symptom ◽  
English Language ◽  
Negative Symptoms ◽  
Meta Analysis ◽  
Grey Literature ◽  
Symptom Burden ◽  
Cochrane Library ◽  
Individual Participant ◽  
The Relationship

Abstract Background Healthy metacognition involves several capacities, including the ability to integrate information about the self and others in order to formulate ways of coping with social challenges and psychological distress. Multiple studies have demonstrated that reduced general metacognitive capacity is predictive of the development and persistence of overall negative symptom burden. However, there have been no published analyses investigating how specific sub-components of metacognition influence the expression of individual negative symptoms. We aggregated individual participant data from studies reporting measures of subtypes of metacognitive functioning and examined the strength of association with specific negative symptoms. Methods PsycINFO, EMBASE, MEDLINE, Cochrane Library and grey literature databases were searched for eligible studies. Forwards and backwards citation searching and contacting of study authors revealed additional datasets not identified in the original search. Included studies assessed negative symptoms and metacognition using interview-based measures in participants aged 16 years or older. Selection was restricted to quantitative research, excluding case studies, and only English language publications were screened. Experimental and observational studies were screened sequentially at title, abstract and full-text level to determine whether they met search criteria. A second reviewer independently screened a proportion of records to check the reliability of inclusion/exclusion judgements (Cohen’s Kappa = 0.74). Participant data and metadata of included studies were extracted and compiled combining original author and report information for all pre-specified outcomes where available. The proposed plan for the systematic review and meta-analyses was also pre-registered on PROPSERO (CRD42019130678). Results 97 unique reports were identified, of which 30 included negative symptom specific hypotheses. Samples overlapped substantially across publications with these 97 reports corresponding to 30 unique datasets. The raw individual participant level data for 23 of the 30 unique datasets was obtained. Preliminary analyses investigated the relationship between components of metacognition measured with the MAS-A (Lysaker et al., 2005), and the original negative symptoms subscale score of the PANSS (Kay et al., 1987) to maximise available data. We will discuss the results, which suggest that there are distinct relationships between subscales of metacognition and negative symptoms. We will also discuss the limitations of these results including a limited scope for analysing covariates due to the computational complexity of the models used, and difficulties in handling the diversity of data present in the meta-analysis. We will also discuss why high heterogeneity might be present, and provide further support for analysis investigating the relationship between individual negative symptoms and components of metacognition. Discussion The data suggest there is complexity in the relationship between components of metacognition and individual negative symptoms. It is for subsequent analyses to determine whether individual negative symptoms have distinct relationships with each metacognitive capacity, and whether the variation in the strength of these associations could explain the high heterogeneity observed.

A Systematic Review and a Meta-Analysis of the Relationship Between Problem Finding and Creativity

2017 ◽  
Author(s):  
Ahmed M. Abdulla ◽  
Sue Hyeon Paek ◽  
Rodney Dishman ◽  
Bonnie Cramond ◽  
Mark A. Runco
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Problem Finding ◽  
The Relationship

A Meta Analytic Review of the Relationship between Emotional Intelligence and Leadership Effectiveness

2019 ◽  
Vol 118 (9) ◽  
pp. 118-126
Author(s):  
Augusty P. A ◽  
Jain Mathew
Keyword(s):  
Systematic Review ◽  
Emotional Intelligence ◽  
Direct Relationship ◽  
Effective Leadership ◽  
Leadership Effectiveness ◽  
Meta Analysis ◽  
Correlation Coefficients ◽  
Review Of Literature ◽  
Analytic Review ◽  
The Relationship

The study evaluates the relationship between Emotional Intelligence and Leadership Effectiveness through a Systematic Review of Literature. The relationship has been evaluated in two steps. First, a Systematic review of literature was done to provide a theoretical framework to link the dimensions of Emotional Intelligence to the elements of effective leadership. Meta-analysis was then used to consolidate empirical evidence of the relationship. The studies for the meta-analysis were sourced from Pro Quest and EBSCO and the correlation coefficients of the studies were analysed. Only articles that presented the direct relationship between the variables were included in the study. The results of the analysis revealed a strong, statistically significant relationship between emotional intelligence and effective leadership. The findings of the study provide evidence for the proposition that Emotional Intelligence and Leadership Effectiveness are interrelated.

Systematic review and meta-analysis of Altruistic and Game-playing Love

2020 ◽  
Author(s):  
Hossein Dabiriyan Tehrani ◽  
Sara Yamini
Keyword(s):  
Systematic Review ◽  
Subgroup Analysis ◽  
Meta Analysis ◽  
Game Playing ◽  
Love Styles ◽  
Collectivistic Culture ◽  
Meta Regression ◽  
Collectivistic Cultures ◽  
The Relationship

This systematic review aimed to find attitudes toward Altruistic and Game-playing love styles across individualistic and collectivistic cultures. Addressing major moderators concerning Altruistic and Game-playing love styles are the secondary objectives of this review. This review included 102 articles comprising samples from 37 countries (N = 41997). The findings of this meta-analysis show that there is a collectivistic and individualistic difference in Game-playing but not in the Altruistic love style. Collectivistic and individualistic cultures, on average, demonstrate the same perception concerning the Altruistic love style, whereas collectivistic culture shows the Game-playing love style more strongly. To explain the role of moderators in key measures, the subgroup analysis and meta-regression show that both Game-playing and Altruistic love styles decline by increasing the length of the relationship. Likewise, having children affects these love styles such that the Altruistic love style is improved, and the Game-playing love style is reduced by the presence of children in families.

scholarly journals Misuse of medication in adult substance misuse services: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e047283
Author(s):  
Rosalind Gittins ◽  
Louise Missen ◽  
Ian Maidment
Keyword(s):  
Systematic Review ◽  
Substance Misuse ◽  
Data Extraction ◽  
Meta Analysis ◽  
Grey Literature ◽  
Opioid Analgesics ◽  
Physical And Mental Health ◽  
Qualitative Synthesis ◽  
Treatment Services ◽  
The Impact

IntroductionThere is a growing concern about the misuse of over the counter (OTC) and prescription only medication (POM) because of the impact on physical and mental health, drug interactions, overdoses and drug-related deaths. These medicines include opioid analgesics, anxiolytics such as pregabalin and diazepam and antidepressants. This protocol outlines how a systematic review will be undertaken (during June 2021), which aims to examine the literature on the pattern of OTC and POM misuse among adults who are accessing substance misuse treatment services. It will include the types of medication being taken, prevalence and demographic characteristics of people who access treatment services.Methods and analysisAn electronic search will be conducted on the Cochrane, OVID Medline, Pubmed, Scopus and Web of Science databases as well as grey literature. Two independent reviewers will conduct the initial title and abstract screenings, using predetermined criteria for inclusion and exclusion. If selected for inclusion, full-text data extraction will be conducted using a pilot-tested data extraction form. A third reviewer will resolve disagreements if consensus cannot be reached. Quality and risk of bias assessment will be conducted for all included studies. A qualitative synthesis and summary of the data will be provided. If possible, a meta-analysis with heterogeneity calculation will be conducted; otherwise, Synthesis Without Meta-analysis will be undertaken for quantitative data. The reporting of this protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Ethics and disseminationEthical approval is not required. Findings will be peer reviewed, published and shared verbally, electronically and in print, with interested clinicians and policymakers.PROSPERO registration numberCRD42020135216.

scholarly journals Caffeine and Cognitive Functions in Sports: A Systematic Review and Meta-Analysis

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 868
Author(s):  
Jorge Lorenzo Calvo ◽  
Xueyin Fei ◽  
Raúl Domínguez ◽  
Helios Pareja-Galeano
Keyword(s):  
Systematic Review ◽  
Reaction Time ◽  
Cognitive Performance ◽  
Cognitive Functions ◽  
Web Of Science ◽  
Meta Analysis ◽  
Caffeine Intake ◽  
Inclusion Criteria ◽  
Research Protocols ◽  
The Relationship

Cognitive functions are essential in any form of exercise. Recently, interest has mounted in addressing the relationship between caffeine intake and cognitive performance during sports practice. This review examines this relationship through a structured search of the databases Medline/PubMed and Web of Science for relevant articles published in English from August 1999 to March 2020. The study followed PRISMA guidelines. Inclusion criteria were defined according to the PICOS model. The identified records reported on randomized cross-over studies in which caffeine intake (as drinks, capsules, energy bars, or gum) was compared to an identical placebo situation. There were no filters on participants’ training level, gender, or age. For the systematic review, 13 studies examining the impacts of caffeine on objective measures of cognitive performance or self-reported cognitive performance were selected. Five of these studies were also subjected to meta-analysis. After pooling data in the meta-analysis, the significant impacts of caffeine only emerged on attention, accuracy, and speed. The results of the 13 studies, nevertheless, suggest that the intake of a low/moderate dose of caffeine before and/or during exercise can improve self-reported energy, mood, and cognitive functions, such as attention; it may also improve simple reaction time, choice reaction time, memory, or fatigue, however, this may depend on the research protocols.

scholarly journals Knowledge and utilisation of preconception care and associated factors among women in Ethiopia: systematic review and meta-analysis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Alemu Degu Ayele ◽  
Habtamu Gebrehana Belay ◽  
Bekalu Getnet Kassa ◽  
Mulugeta Dile Worke
Keyword(s):  
Systematic Review ◽  
Antenatal Care ◽  
Associated Factors ◽  
Preconception Care ◽  
Meta Analysis ◽  
Grey Literature ◽  
Database Systems ◽  
Child Health Services ◽  
Measurement Tool ◽  
Care Services

Abstract Background Preconception care is the provision of biomedical, behavioural, and social health interventions provided to women and couples before conception. However, in Ethiopia, little is known and practised to support preconception care. Therefore, this study aimed to assess women’s knowledge and utilisation of preconception care and its associated factors in Ethiopia using systematic review and meta-analysis. Method In the current meta-analysis, variables were searched from different electronic database systems, which included PubMed, Google Scholar, EMBASE, HINAR, Scopus, Web of Sciences, and Grey literature. Data were extracted using a standardised data collection measurement tool. The data were analysed by using STATA 14 statistical software. I2 tests assessed heterogeneity between the studies. A random-effect model was used to forecast the pooled knowledge and utilisation of preconception care. Results Thirteen full-text studies were included. The pooled prevalence of knowledge and utilisation of preconception care among women in Ethiopia was 30.95% and 16.27% respectivelly. Secondary education (OR = 2.78, 95% CI,2.01–3.85), college and above (OR = 5.05, 95% CI,2.70–9.44), and antenatal care (OR = 3.89, 95% CI, 1.69–8.98) were significantly associated with knowledge level whereas; age (OR = 2.43, 95% CI, 1.30–4.53) and knowledge on preconception care (OR = 3.95, 95% CI,2.35–6.62) were positively associated with utilisation of preconception. Conclusions Women’s level of knowledge and utilisation of preconception care was significantly low. Educational status and antenatal care follow-up were factors shown to affect knowledge of preconception care. Age and having a sound knowledge of preconception care indicated a significant association towards utilisation of preconception care. Thus, integrating preconception care strategies and policies that can address all the components of preconception care services with other maternal and child health services will be essential when designing effective implementation strategies to improve preconception care uptake. Besides this, advocating for better education for women, awareness creation, and increasing antenatal care services are essential. Prospero registration: CRD42020218062

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