scholarly journals Histomorphological spectrum of ovarian tumors - A tertiary care center experience

2022 ◽  
Vol 13 (1) ◽  
pp. 111-117
Author(s):  
K Sampurna ◽  
B Jyothi
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Age Distribution ◽  
Female Genital Tract ◽  
Germ Cell Tumors ◽  
Ovarian Tumors ◽  
Reproductive Age ◽  
Malignant Neoplasms ◽  
Histological Features ◽  
Epithelial Tumors

Background: Ovarian tumors are a heterogeneous group of neoplasms with variable clinical, morphological, and histological features. Ovarian cancer is the leading cause of death in females. Aims and Objectives: (1) To study and characterize the ovarian tumors based on gross and histopathological features. (2) To study prevalence and age distribution of various ovarian tumors. (3) To study the clinical features in patients with ovarian tumors. (4)To compare the frequency of benign and malignant neoplasms of the ovary with other studies. Materials and Methods: This is a prospective study conducted in Upgraded Department of Pathology, Modern Government maternity hospital, and Osmania General Hospital, Hyderabad, Telangana from March 2018 to February 2021. A total of 200 ovarian tumors were studied. Results: Out of 200 ovarian tumors, 132 were benign, seven were borderline and 61 were malignant. The surface epithelial tumors were the most common tumors accounting for 159cases (79.5%), germ cell tumors were seen in 27 cases (13.5%), sex-cord stromal tumors formed 10 cases (5%), and metastasis in 4 cases (2%). Conclusion: Ovary is a common site of tumors in the female genital tract and usually presents with a variety of clinocomorphological and histological features. Benign are the most common, of these surface epithelial tumors are the commonest, affects mainly reproductive age group.

scholarly journals Clinicopathological analysis of ovarian tumours: a 10 year retrospective study

2018 ◽  
Vol 7 (8) ◽  
pp. 3216
Author(s):  
Sahana N. Naik ◽  
Sunil Kumar K. S. ◽  
Girija B.
Keyword(s):  
Malignant Tumors ◽  
Female Genital Tract ◽  
Germ Cell Tumors ◽  
Mucinous Cystadenoma ◽  
Ovarian Tumors ◽  
Reproductive Age ◽  
Benign Tumors ◽  
Age Group ◽  
Epithelial Tumors ◽  
Neoplastic Lesions

Background: Ovarian tumors account for 30% of all cancers of female genital tract which represents the sixth most common cancer and fourth leading cause of death in women. The present study was done with an objective to determine the frequency and distribution of various ovarian tumors and to study their clinical and histopathological presentations.Methods: It is a retrospective observational study of patients with ovarian tumors subjected to surgery in the department of obstetrics and gynecology, SDM College of Medical Sciences and Hospital from January 2005 to December 2015.Results: There were 642 cases comprising of 77.7% of neoplastic lesions and 22.3% of non-neoplastic lesions. Majority of the ovarian tumors (83%) were seen in the age group of 20 to 50 years. Mean age for ovarian tumors was 38 years.  Among the neoplastic lesions 84% were benign, 14.2% were malignant and 1.8% were borderline tumors. Surface epithelial tumors were the commonest tumors (60.9%) followed by germ cell tumors (12.8%).  Serous cystadenoma was the most common benign tumors (47.1%) followed by mucinous cystadenoma (18.4%). Among the ovarian malignant tumors; serous cystadenocarcinoma was the most common (4.5%) followed by mucinous cystadenocarcinoma (2.6%). Chocolate cysts were the most common among the non-neoplastic lesions (36.4%).Conclusions: Ovarian neoplastic lesions were more common than non-neoplastic lesions. Benign ovarian tumors were common in reproductive age group.  The mean age of occurrence for ovarian tumor was 38 years. The most common neoplasm was surface epithelial tumors, of which serous tumors was the commonest. Chocolate cysts were the most frequently encountered histopathological finding among the non-neoplastic lesions.

Histopathological profile of ovarian tumors in a tertiary care center- a descriptive study

2021 ◽  
Vol 9 (4) ◽  
pp. 1010
Author(s):  
Anitha Pallikkara V. ◽  
Shameem K. Ummer Ali
Keyword(s):  
Germ Cell ◽  
Malignant Tumors ◽  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Germ Cell Tumors ◽  
Ovarian Tumors ◽  
Benign Tumors ◽  
Medical College ◽  
Epithelial Tumors

Background: Ovarian neoplasms are a heterogeneous group of tumors with varied clinical, morphological and histological features. Ovarian cancer accounts for about 3% of all cancer in females and is the 5th most common cause of death due to cancer because most ovarian tumors spread beyond ovary by the time of diagnosis. The objective of the study was to document the histological pattern and prevalence of ovarian tumors in specimens received at department of pathology government medical college Alappuzha.Methods: This was a prospective study of 18 months duration which comprised of 245 cases of ovariectomy and ovariotomy specimens received in the department of pathology, govt. T.D medical college Alappuzha, Kerala. After detailed and thorough gross examination of the specimens, bits from representative areas were routinely processed and stained with H and E. Tumors were classified as per WHO classification. Appropriate immunohistochemical studies were performed wherever required.Results: Out of 245 cases studied, majority were benign tumors (78.36%), followed by malignant tumors (15. 11%). Borderline tumors comprised (6.53%) of the total cases. Age groups studied ranged from 11-70 years. Epithelial tumors were the most common (76.32%) followed by germ cell tumors (17.55%), sex cord stromal tumors (5.03%) and carcinoma arising in germ cell tumors (0.81%). Serous cystadenoma was found to be the commonest benign tumor and serous cystadenocarcinoma was the commonest malignant ovarian neoplasm.Conclusions: Surface epithelial tumors were the most common ovarian tumors. The maximum number of tumors were noted in the age group 21-40 years. Malignant tumors were common above 40 years. 

scholarly journals Histological Patterns of Ovarian Neoplasms – A Five Year Experience in North-East India

2018 ◽  
Vol 7 (1) ◽  
pp. 1576
Author(s):  
Saha Manasi ◽  
Banerjee Alpana ◽  
Datta Abhijit
Keyword(s):  
Ovarian Neoplasms ◽  
Age Distribution ◽  
Female Genital Tract ◽  
Mucinous Cystadenoma ◽  
Malignant Neoplasm ◽  
Cystic Teratoma ◽  
Ovarian Tumors ◽  
Mucinous Cystadenocarcinoma ◽  
Malignant Neoplasms ◽  
Epithelial Tumors

<p><strong>Background:</strong> Ovary is one of the common sites of neoplasm in females. They manifest in wide spectrum of clinical, morphological and histological features. Ovary is the second most common site of primary malignancy in female genital tract.</p><p><strong>Objectives:</strong> To study the frequency of different histological types of ovarian tumors and to analyze age distribution of these tumors.</p><p><strong>Materials and Methods:</strong> This was a retrospective study of all cases of ovarian tumors received at Pathology Department of Agartala Government Medical College during the period of 5 years from January 2012 to December 2016.</p><p><strong>Results:</strong> A total number of 242 cases were studied. Among these 189 cases (78.1%) were benign, 12 cases (4.96%) were borderline and 41 cases (16.94%) were malignant. Benign neoplasms were most commonly seen between 3<sup>rd</sup> and 5<sup>th</sup> decade of age whereas malignant neoplasms after 4<sup>th</sup> decade. Serous cystadenoma was the commonest benign tumor followed by mucinous cystadenoma and mature cystic teratoma. Among the malignant surface epithelial tumors, mucinous cystadenocarcinoma was most common, followed by serous cystadenocarcinoma.</p><p><strong>Conclusion:</strong> Benign ovarian neoplasms outnumber the malignant ones in all age groups. Surface epithelial tumors are the most common class of tumors and mucinous cystadenocarcinoma is the commonest malignant neoplasm.</p>

scholarly journals CLINICOPATHOLOGICAL STUDY OF SURFACE EPITHELIAL OVARIAN TUMORS- A TERTIARY CARE CENTER STUDY.

2020 ◽  
pp. 1-4
Author(s):  
Priyanka Nimbalkar Jadhav ◽  
Raviraj Jadhav
Keyword(s):  
Histopathological Examination ◽  
Wide Spectrum ◽  
Care Center ◽  
Tertiary Care ◽  
Female Genital Tract ◽  
Mucinous Cystadenoma ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Histopathological Diagnosis ◽  
Care Hospital

Background: Ovarian tumors are one of the most common tumors, which occur in female genital tract. Despite the newer techniques in imaging and molecular biology, the diagnosis of ovarian tumors primarily depends on histopathological examination. Ovarian tumors manifests a wide spectrum of clinical, morphological and histological features. The aim of the study was to find the incidence of surface epithelial ovarian tumors in a tertiary referral centre. Materials and methods: A retrospective data of 3 years were collected for surface epithelial ovarian tumors submitted to the pathology department of the tertiary care hospital and analysed. The correlation of these surface epithelial ovarian tumors was done with age, clinical presentation and histomorphological patterns. Non-neoplastic lesions like simple ovarian cysts, tubo-ovarian mass and polycystic ovaries were excluded. Results: A total number of 56 cases were studied. Out of which 44 cases were benign and 12 cases were malignant. Maximum cases were observed between 21 to 30 years. Mass per abdomen was the most common presentation(36%) followed by mass and pain in abdomen(27%).Serous cystadenoma formed maximum 28 cases(50%) followed by Mucinous cystadenoma(16 cases) 28 % , Serous cysadenocarcinoma formed 5cases (9%), followed by Mucinous cystadenocarcinoma 3 cases(5%) & 2 cases each(4%) of clear cell carcinoma and endometrioid carcinoma were noted. The most common histopathological type of benign and malignant tumor was serous cystadenoma (50.2%) and serous cystadenocarcinoma(9%) respectively. Conclusion: In the study majority (78.6%) of the surface epithelial ovarian tumors were benign. Malignancy was seen in (21.4)% of the cases. Surface epithelial tumours present a great challenge to the gynecologic oncologist because non-neoplastic ovarian lesions can form a pelvic mass and potentially mimic a neoplasm. Correct histopathological diagnosis of surface epithelial ovarian tumors is of prime importance in view of their behavioral predictability and clinical correlation for proper management of the patient.

scholarly journals Histopathological spectrum of ovarian tumors: an institutional perspective

2018 ◽  
Vol 6 (8) ◽  
pp. 2639
Author(s):  
Angela Phukan ◽  
Meghna Borgogoi ◽  
Shaolima Ghosh
Keyword(s):  
Ovarian Tumor ◽  
Malignant Tumors ◽  
Age Distribution ◽  
Germ Cell Tumors ◽  
Cystic Teratoma ◽  
Ovarian Tumors ◽  
Benign Tumors ◽  
Institutional Perspective ◽  
Epithelial Tumors ◽  
Age Range

Background: Globally ovarian tumor is one of the leading causes of cancer death among women. Ovarian tumor has varied histiogenesis, clinical behavior and malignant potential. The aims and objectives of the present study is to study the histopathological pattern and age distribution of the ovarian tumors.Methods: A total of 84 cases were studied from January 2016 to December 2016. They were reviewed and analyzed for age, histopathological findings and clinical presentations. Classification was done according to WHO histologic classification of ovarian tumors.Results: Of the 84 cases, 75% were benign, 3.6% cases were borderline and 21.4% cases were malignant. Among the histological subtypes surface epithelial tumors comprised of 66.7% followed by germ cell tumors (23.9%). Serous cystadenoma (36.9%) was the most common benign tumor followed by mature cystic teratoma (17.9%). Serous cyst adenocarcinoma (10.7%) was the most common malignant tumour. Tumors were seen over age range of 10-78 years and maximum number of cases were in the 4th to 6th decade. Younger age group primarily presented with benign tumors whereas malignant tumors were common in elderly age group.Conclusions: Surface epithelial tumors were the commonest ovarian tumor. Maximum numbers of ovarian tumors were in the age range 40-59years and malignant tumors were common in >40 years of age.

scholarly journals Histopathological spectrum of neoplastic and non-neoplastic breast lesions: A three years study in rural tertiary care center.

2020 ◽  
Vol 7 (01) ◽  
pp. 4721-4725
Author(s):  
Dr. Sanjeev Kumar Singh ◽  
Dr. Geeta Maurya ◽  
Dr. Pinki Pandey ◽  
Dr. Rashmi
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Care Center ◽  
Benign Lesion ◽  
Tertiary Care ◽  
Age Distribution ◽  
Morbidity And Mortality ◽  
Histopathological Diagnosis ◽  
Breast Lesions ◽  
Neoplastic Lesions

Background: Breast tumours are very common cause of morbidity and mortality worldwide specially in developing countries. Breast lesions show broad spectrum of disease patterns in respect to benign, malignant, and non-neoplastic. Breast cancer is one of the most frequently occurring cancer among women. Objective: To study the frequency, age distribution, clinical and histological patterns of neoplastic and non-neoplastic lesions of breast in this rural population. Material and methods: This observational study was conducted over a duration of three years. In which we studied 210 cases of breast lesions. Specimens were received in department of pathology. Grossing, tissue processing, staining done according to standard protocol. Haematoxylin and eosin (H&E) stained sections were examined under microscope to categorise different type of lesions in the form of non-neoplastic and neoplastic. Results:  Out of 210 breast lesions, fibroadenoma was the commonest (114 cases) benign lesion. While invasive ductal carcinoma (70 cases) was commonest in malignant category. Non neoplastic lesions stand on third place, study showed 6 cases out of 210 total cases, in which acute mastitis (4 cases) was most common. Benign tumours were mostly seen in 2nd and 3rd decade and malignant tumour mainly in 5th and 6th decade Conclusion: Early histopathological diagnosis of breast lesions is very important to differentiate between benign and malignant lesions. Large number of cases of invasive ductal carcinoma (>33% of all cases) were seen in our study, which is a serious concern. So, generation of awareness among women is need of time to reduce the morbidity and mortality specially in Indian rural setup

scholarly journals Complications and Outcome of Pregnancy in Extremes of Reproductive Age Groups: Experience at Tertiary Care Center

2016 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Manju Lata Verma ◽  
Sabuhi Qureshi ◽  
Uma Singh ◽  
Nisha Singh ◽  
Pushpa Lata Sankhwar
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Reproductive Age ◽  
Tertiary Care Center

scholarly journals Knowledge, attitude and experiences of menopause in the postmenopausal women at a tertiary care center: a cross sectional study

2018 ◽  
Vol 7 (11) ◽  
pp. 4758
Author(s):  
Shivraj More ◽  
Sujatha P. ◽  
Karthiga Karthiga
Keyword(s):  
Postmenopausal Women ◽  
Care Center ◽  
Tertiary Care ◽  
Educational Status ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Tertiary Care Center ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Government

Background: Menopause is an inevitable milestone in the reproductive life of every woman. The objective is to investigate menopausal knowledge, attitude, symptoms and management among the participants, to identify the differences according to their educational status and to examine correlations of knowledge, attitude and symptoms pertaining to menopause.Methods: This cross-sectional study was conducted for a period of 10 months in postmenopausal women attending a tertiary care center in Pondicherry, India with a structured questionnaire developed on the basis of the objective of the study.Results: 330 postmenopausal women were recruited, and all were aware of their postmenopausal status. Mean age at menopause was 45.91±2.66 years. 54.5% were aware about what menopause was while 5.5% were unaware. 12.1% had proper knowledge about cause of menopause, whereas 3.6% said it is due to god’s decision / turning point. Most prevalent symptoms were tiredness (89.6%) followed by vasomotor symptoms like hot flushes (88.5%) and night sweats (80.3%). Only 2.1% had used HRT for menopausal symptoms.Conclusions: Depth of knowledge is more important when concern is about greater health disrupter which tends to be imperceptible for a long time such as bone health and cardiovascular risk profile. Thus, the government could concentrate on providing health services to women in post reproductive age group also besides women in the reproductive age.

scholarly journals Distribution of various histopathological types of ovarian tumors: A study of 212 cases from a tertiary care center of Eastern Uttar Pradesh

2019 ◽  
Vol 11 (01) ◽  
pp. 075-081 ◽  
Author(s):  
Neha Gupta ◽  
Mahima Yadav ◽  
Vikas Gupta ◽  
Deepshikha Chaudhary ◽  
Shashikant C. U. Patne
Keyword(s):  
Germ Cell ◽  
Who Classification ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Germ Cell Tumors ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Care Hospital ◽  
Stromal Tumors ◽  
Sex Cord Stromal Tumors

Abstract BACKGROUND: Ovarian tumors are one of the leading cancers in females with variable pathological types. This study describes the distribution, clinical and pathological details of various histopathological types of ovarian tumors in a tertiary care hospital in North India. MATERIALS AND METHODS: A retrospective data of 3 years were collected for ovarian tumors submitted to the pathology department of a tertiary care hospital. Data were classified according to the latest World Health Organization (WHO) Classification into epithelial tumors, germ cell tumors, sex cord–stromal tumors, and others. RESULTS: A total of 212 cases of ovarian tumors were studied, 186 were unilateral and 26 were bilateral. Resection specimen, part of specimen, and block review formed 80.2%, 15.1%, 4.7%, respectively. Epithelial tumors formed the majority in 71.7% of cases followed by germ cell tumors (22.2%), sex cord–stromal tumors (3.8%) and others (2.3%). Maximum number of cases in the respective groups occurred in the age groups 31–40, 21–30, 51–60, and 41–50 years, respectively. Overall, benign tumors were 63.7%, malignant tumors were 31.1%, and borderline were 5.2%. The most common histopathological type of benign and malignant tumor was benign serous cystadenoma (18.8%) and serous carcinoma (9.9%), respectively. CONCLUSION: In the present study, ovarian tumors were classified according to the WHO classification, epithelial and germ cell tumors were the major types of ovarian tumors. Benign epithelial tumor formed the majority with 46.2% cases. Serous cystadenoma and mature cystic teratoma were the predominant type of epithelial and germ cell tumors, respectively.

Incidence of Involvement of Nipple Areola Complex in Breast Cancer

2015 ◽  
Vol 24 (Number 1) ◽  
pp. 33-38
Author(s):  
Md. R Hoq ◽  
A Sayeed ◽  
B Khan ◽  
R Parvin ◽  
S I Khan
Keyword(s):  
Breast Cancer ◽  
Care Center ◽  
Tertiary Care ◽  
Age Distribution ◽  
Oncologic Outcome ◽  
Breast Cancer Surgery ◽  
Breast Cancer Patients ◽  
Areola Complex ◽  
Areolar Complex ◽  
Study Population

In this prospective study, fifty cases of breast cancer were studied in a tertiary care center & different hospitals of Dhaka city for one year, aimed to determine the incidence of malignant involvement of NAC in breast cancer patients of our country with clinically uninvolved nipples from history and postoperative histopathological reports of mastectomy specimens. The age distribution of Breast cancer varied from 25 to 75 years. Highest incidence was in 5th and 6th decades numbering 30 (60%) cases. Incidence of 3rd decades was 8 (16%) cases and in 7th decades was 12 (24%) casesin relation to menstrual cycle Breast Ca incidence is more in post-menopausal women numbering 28 (56%).Lump size of most of the study population found within 2-Scm (T2 stage). Incidence of axillaty lymph node metastasis found positive in 28 patients (56%) and no metastasis in 22 patients (44%). Of 50 patients maximum no 22 (44%) found with moderately differentiated tumour, 16 (32%) patients found poorly differentiated, differentiation could not be assessed in 12 (24%) patient and well differentiated tumour found in only 2 (4%) patients. The most common histological type found in the study population is IDCC 44 (88%). Skin involvement was 0% and only 2% patients have malignant involvement of NAC from underling breast cancer. The conclusion in respect to this study is, Nipple areolar complex can be preserved with breast reconstruction in carefully selected patients going for breast cancer surgery with safe oncologic outcome.

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