scholarly journals The survival story of a diabetic ketoacidosis patient with blood sugar levels of 1985 mg/dL

2017 ◽  
Vol 8 (4) ◽  
pp. 60-61 ◽  
Author(s):  
Manoj Gopalakrishnan ◽  
Robin George Manappallil ◽  
Dipu Ramdas ◽  
Jishnu Jayaraj

No abstarctAsian Journal of Medical Sciences Vol.8(4) 2017 60-61

2016 ◽  
Vol 7 (6) ◽  
pp. 32-35
Author(s):  
J P Ghildiyal ◽  
Archna Ghildiyal ◽  
Sarsij Sharma ◽  
Bushra Iqbal ◽  
Shraddha Singh

Background: Perioperative hyperglycemia is frequently encountered in clinical practice. Recent evidence suggests that hyperglycemia plays a significant role in the development of postoperative infections (POI). Major focus has been placed on whether hyperglycemia, as an independent risk factor, is associated with increased infection. The optimal targeted blood glucose range to prevent POI remains unclear, especially in the intra-operative period.Aims and Objectives: To study the association between  peri-operative hyperglycemia to the subsequent risk of post-operative infections through a prospective  observational study.Materials and Methods: A prospective study of 101 patients undergoing different types of general surgery procedures followed up to 30 days post-operatively was done. Random  blood Sugar (RBS) was taken (1) Pre-operatively (2) Intra-operatively (3) Postoperatively- after 6, 24 and 48 hours. Primary end points of the study were (1)  Surgical wound infection (2) Urinary tract infection (3) Septicemia.Results: Out of 101 patients 57 developed perioperative hyperglycemia (incidence- 56.4%). In normoglycemic  group of patients infection rate was 4.5% (2/44) as compared to 26.3% (15/57) in perioperative hyperglycemic group.Conclusion: The present study provides a convincing evidence of an association between perioperative hyperglycemia and post-operative infection apart from giving a possible relationship between preoperative blood sugar levels and postoperative infection.Asian Journal of Medical Sciences Vol.7(6) 2016 32-35


2020 ◽  
Vol 7 (1) ◽  
pp. 34-36
Author(s):  
Dr. Wasim Feroz ◽  
Dr. Sandeep Nale ◽  
Dr. H S Rawat

Diabetic ketoacidosis (DKA) is a life threatening metabolic disorder and a known complication of Diabetes mellitus, caused by insulin deficiency or insulin resistance, which allows the catabolism of free fatty acids into ketone bodies, with high blood sugar levels. A rare variant of it is, euglycemic diabetic ketoacidosis (EKDA). We report a case of 60 year old female who was posted for Posterior lumbar interbody fusion (PLIF) and had this complication postoperatively. We believe that this case would serve as a reminder to all practitioners and intensivist to consider ketosis in a diabetic patient despite their serum glucose levels being within the normal range and all anaesthetist to consider the use of insulin during the intra op period even the blood sugar level is normal in peri operative period. This case report summarizes, in brief, the etiology, pathophysiology and treatment of EDKA.


1985 ◽  
Vol 54 (02) ◽  
pp. 413-414 ◽  
Author(s):  
Margarethe Geiger ◽  
Bernd R Binder

SummaryWe have demonstrated previously that fibrin enhanced plasmin formation by the vascular plasminogen activator was significantly impaired, when components isolated from the plasma of three uncontrolled diabetic patients (type I) were used to study plasminogen activation in vitro. In the present study it can be demonstrated that functional properties of the vascular plasminogen activators as well as of the plasminogens from the same three diabetic patients are significantly improved after normalization of blood sugar levels and improvement of HbAlc values. Most pronounced the Km of diabetic vascular plasminogen activator in the presence of fibrin returned to normal values, and for diabetic plasminogen the prolonged lag period until maximal plasmin formation occurred was shortened to almost control values. From these data we conclude that the observed abnormalities of in vitro fibrinolysis are not primarily associated with the diabetic disease, but might be secondary to metabolic disorders caused by diabetes.


1972 ◽  
Vol 33 (3) ◽  
pp. 722-733 ◽  
Author(s):  
John W. Dundee ◽  
Martin Isaac ◽  
Elizabeth A. Davis ◽  
Brian Sheridan

2020 ◽  
Vol 9 (5) ◽  
pp. 185-192
Author(s):  
Hafsa Dellaoui ◽  
Abdelkrim Berroukche ◽  
Bakhta Bouzouira ◽  
Narimen Taibi ◽  
Mohamed Zouidi ◽  
...  

Cadmium (Cd) is widespread in the environment. Cd toxicity targets liver and renal tissues and generates oxidative stress. Medicinal plants produce antioxidants scavenging reactive oxygen species (ROS) and chelate heavy metals. This study aimed to investigate the preventive effects of Myrtus communis leaves hydro-methanol extract (HME) and aqueous extract (AE) on Cdinduced toxicity. The experiments were carried out, during 30 days, on male rats; GR1 (controls), GR2 treated with CdCl2 (18 mg/kg), GR3 co-treated with HME (1 g/kg) and Cd (18 mg/kg), GR4 co-treated with AE (1 g/kg) and Cd (18 mg/kg), GR5 with HME and GR6 with AE. Cd induced changes in biochemical parameters (transaminases, urea, creatinine and blood sugar)related to hepato renal function, increased tissue mortification and decreased animals’ body weight. While the treatment animals, with M. communis leaves (HME) or (AE), regulated blood sugar levels. Hepatic steatosis and loss of glomeruli were particularly induced either by Cd or a co-treatment with Cd and plant extracts. M. communis extracts (HME and EA) can regulate blood sugar levels and prevent cadmium accumulation.


PEDIATRICS ◽  
1966 ◽  
Vol 37 (4) ◽  
pp. 597-604
Author(s):  
Doman K. Keele ◽  
Jacob L. Kay

Simultaneous plasma free fatty acid (FFA) and blood sugar levels were determined for fasting newborn infants during the first 24 hours of life, for their cord bloods, and for their mothers at delivery. The following observations were made. In control infants the mean FFA level rose about three times the cord level after birth and was accompanied by a 25% drop in the mean blood sugar level. Thereafter, the mean blood sugar level remained relatively constant, but the mean FFA level varied from 2½ to 3 times the cord level. There was no significant correlation between the length of maternal fasting prior to delivery and the infant FFA level; there was, however a significant negative correlation between the length of maternal fasting prior to delivery and the infant blood sugar level at 24 hours of age. High FFA levels occurred in the infants of obese mothers and low levels were observed in infants with delayed respirations, in infants of preeclamptic mothers, and in infants of diabetic mothers.


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