scholarly journals Association of perioperative hyperglycemic state with postoperative infection

2016 ◽  
Vol 7 (6) ◽  
pp. 32-35
Author(s):  
J P Ghildiyal ◽  
Archna Ghildiyal ◽  
Sarsij Sharma ◽  
Bushra Iqbal ◽  
Shraddha Singh

Background: Perioperative hyperglycemia is frequently encountered in clinical practice. Recent evidence suggests that hyperglycemia plays a significant role in the development of postoperative infections (POI). Major focus has been placed on whether hyperglycemia, as an independent risk factor, is associated with increased infection. The optimal targeted blood glucose range to prevent POI remains unclear, especially in the intra-operative period.Aims and Objectives: To study the association between  peri-operative hyperglycemia to the subsequent risk of post-operative infections through a prospective  observational study.Materials and Methods: A prospective study of 101 patients undergoing different types of general surgery procedures followed up to 30 days post-operatively was done. Random  blood Sugar (RBS) was taken (1) Pre-operatively (2) Intra-operatively (3) Postoperatively- after 6, 24 and 48 hours. Primary end points of the study were (1)  Surgical wound infection (2) Urinary tract infection (3) Septicemia.Results: Out of 101 patients 57 developed perioperative hyperglycemia (incidence- 56.4%). In normoglycemic  group of patients infection rate was 4.5% (2/44) as compared to 26.3% (15/57) in perioperative hyperglycemic group.Conclusion: The present study provides a convincing evidence of an association between perioperative hyperglycemia and post-operative infection apart from giving a possible relationship between preoperative blood sugar levels and postoperative infection.Asian Journal of Medical Sciences Vol.7(6) 2016 32-35

2021 ◽  
Vol 17 (3) ◽  
pp. 147
Author(s):  
Ginta Siahaan ◽  
Tiarlince Bakara ◽  
Yusnita Yusnita ◽  
Kasmiyeti Kasmiyeti

Correlation of macronutrient intake with body mass index, blood sugar levels, and total blood protein in drug usersBackground: Random blood sugar level and total blood protein need to be measured among drug users because their macronutrient intakes (carbohydrates, fat, protein, and energy) are not appropriate to the pattern of daily habits before uses drugs. Drug users had decreased appetite during the influence and withdrawal symptoms of drugs with the impacts on their body mass index (BMI). Objective: To analyze the correlation of macronutrient intakes between the random blood sugar level, total blood protein, and BMI drug users.Methods: This research was conducted with a cross-sectional design and observational study. 73 drug users were included in the study with the screening by inclusion criteria. 24-hour food recall was used to collect the macronutrient intakes, random blood sugar levels and total blood protein were monitored by the GOD-PAP method, and BMI was measured by weight and height. Data analysis used Pearson’s correlation test in bivariate and multivariate was carried out by multiple linear regressions. Results: Pearson’s correlation analysis showed that there was a significant correlation between macronutrient intakes (energy, carbohydrate, fat) with random blood sugar level, total blood protein, and BMI. BMI was the most affected by energy (β=0.531), random blood sugar level was the most affected by carbohydrates (β=0.073), and total blood protein was the most affected by protein (β=0.837).Conclusions: Macronutrient intake is significantly related to BMI, random blood sugar levels, and total blood protein in drug users. Community collaboration with related parties such as the public health service and National Narcotics Agency will very quickly detect drug side effects early on eating disorders that will affect the nutritional status of its users.


2019 ◽  
Vol 6 (1) ◽  
pp. 77-80
Author(s):  
Ni Wayan Suniyadewi ◽  
G.N Indraguna Pinatih

Abstract Objective Carbohydrates, proteins, and fats are energy sources needed by the body for performing daily activities and generating primary energy substances. In women who have undergone menopause, the function of thyroid hormone in their body begins to decline and thus affects the ability of the body to produce energy. The purpose of this study was to determine the correlation between the intakes of carbohydrates, proteins, and fats and random blood sugar levels in menopausal women. Methods This study was a correlational analytical research with a cross-sectional design, which was conducted in 72 menopausal women recruited by the purposive sampling technique. In this study, a 24-hour food recall form was used, and randomized blood sugar levels were measured using a glucometer. The analysis of the data was performed using a Pearson product moment and multiple linear regression. Results Carbohydrates and fats together affected random blood sugar levels with an F-value of 25.810 and a p-value of 0.000. Meanwhile, adjusted R2 showed the value of 0.411, indicating that the difference in the intake of carbohydrates and fats together affected random blood sugar levels by 41.1%. Conclusions Intake of carbohydrates and fats affected random blood sugar levels, whereas the rest were influenced by other factors, and protein intake was unrelated to random blood sugar levels in menopausal women.


2017 ◽  
Vol 8 (4) ◽  
pp. 60-61 ◽  
Author(s):  
Manoj Gopalakrishnan ◽  
Robin George Manappallil ◽  
Dipu Ramdas ◽  
Jishnu Jayaraj

No abstarctAsian Journal of Medical Sciences Vol.8(4) 2017 60-61


2017 ◽  
Vol 28 (1) ◽  
pp. 13-23 ◽  
Author(s):  
C Ruth Butlin ◽  
Delwar Hossain ◽  
Suren Singh ◽  
TS Warrender

People with leprosy-related disability in north west Bangladesh were surveyed for diabetes. According to patient reports,97 (27.1/1000) already knew they suffered from diabetes mellitus. Amongst 3573 subjects who underwent a random blood sugar test, anyone with random blood sugar level above 11.0 mmol/l was referred for confirmation of diabetes and advice (111). Unexpectedly, we also found that 30.1% asymptomatic people without a previous diagnosis of diabetes had random blood sugar in the “impaired glucose tolerance” range (i.e. 7.8- 11.0 mmol/l). These people were asked to have a second blood test for fasting blood sugar level, and if this was high (above 7.0 mmol/l) they were advised to have a review with a doctor, preferably at the local diabetic clinic. A sample of people (5%) with Blood sugar levels in the normal range were also invited to have a second test for fasting blood sugar; amongst them only 2 had elevated fasting blood sugar levels (>7.0). Thus another 14 were referred with high fasting blood sugar levels. Of those125 people (considered to be Diabetes suspects) newly-detected with hyperglycaemia, 121 attended a suitable service provider for confirmation/exclusion of diabetes, within 1month of their abnormal blood test. Of them 47 (37.6%) were diagnosed with diabetes. However, 4 people did not take action as advised, and 2 died before attending clinic. Taking into account new diagnoses and old, we estimate a minimum prevalence of 40.3/1,000 amongst leprosy-disabled people in NW Bangladesh. These findings indicate the advisability of routine screening for diabetes amongst people affected by leprosy during routine clinic reviews, and that the ability and motivation to manage their own self-care of people with leprosy related disability and diabetes should be assessed. Appropriate follow up and advice for those with blood sugar in impaired glucose tolerance (IGT) range needs consideration, to minimise their future risk.Bangladesh J Medicine Jan 2017; 28(1) : 13-23


Author(s):  
Rashed Esraa R ◽  
Yadav Abhishek ◽  
Agrawal Abhishek ◽  
Chejara Radhey Shyam ◽  
Singh Aradhana

Author(s):  
Ravinder Singh ◽  
Harbir Kaur Rao ◽  
Anil Sharma ◽  
Thakur Gurjeet Singh ◽  
Abhimanyu Parashar ◽  
...  

Abstract This article is mainly concerned with the simultaneous open model clinical study of the drug named sitagliptin, a potent hyperglycaemic drug against a novel entity of the natural origin BGR- 34 in diabetic subjects. This was a 3-month randomized, parallel, comparative study. One hundred subjects were planned to be included in the study. The patients were randomly divided into two groups and according to the appropriate sample size analysis, both groups consisted of 100 patients, following the inclusion and exclusion criteria. A total of 90 patients (both male and female) of the mean patient age 30-65 years with the type 2 diabetes were enrolled in the phase 4 of this study and then the data were analyzed on the basis of the different test which included HbA1c (glycated haemoglobin), RBS (random blood sugar), FBS (fasting blood sugar) and PPG (postprandial glucose) values. After completion of the data calibration, the results were analyzed and as a result 10-20% decreased values of HBA1C values accompanied with the RBS, FBS and PPG values were seen in the patients undergoing a 12-week course with BGR-34. Based on the results obtained in the present study, it can be concluded that BGR-34 is effective in reducing high blood sugar levels and this reflects that the BGR-34 therapy is more effective drug in the treatment of diabetes suggesting that it is better in efficacy, and reliability with little or no adverse effects.


2010 ◽  
Vol 1 (1) ◽  
pp. 4-5
Author(s):  
Tasneem Sandozi

Objective: To study the effect of AMLODIPINE on blood sugar levels in hypertensive patients.Method: It is a prospective study in which patients were selected from Princess Esra hospital, Hyderabad.Results: This study was done on 20 mild to moderate newly detected hypertensive patients. Statistical analysis shows a highly significant rise in blood sugar level with ‘P' value < 0.001 after 2 and 4 weeks of  using 2.5 to 5 mgm (once daily) amlodipine.Conclusion: As calcium channels are involved in the release of insulin from the β cells of pancreas, calcium channel blockers like amlodipine may cause hyperglycemia when used in hypertensive patients. Further studies are required in this field on a larger number of patients.Keywords: Amlodipine; Calcium channel blockers; Diabetes Mellitus; HypertensionDOI: 10.3126/ajms.v1i1.2777Asian Journal of Medical Sciences Vol.1(1) 2010 p.4-5


2020 ◽  
Vol 5 (2) ◽  
pp. 54-64
Author(s):  
Natalansyah Natalansyah ◽  
Debora Kartika Sari ◽  
Wijaya Atmaja Kasuma

Stress is the condition of an individual who experiences excessive emotional demands, a time problem that makes it difficult to manage efficiently all aspects of life (Richard, 2010). In someone with mild and moderate levels of stress will experience changes in blood sugar levels. This study examines stress levels and random blood sugar levels in nursing students. The purpose of this study was to identify respondent characteristics, stress levels, random blood sugar levels and the relationship between stress levels and random blood sugar levels at the health Polytechnic of Palangka Raya. The research method respondents (f = 39) was assessed using the Perceived Stress Scale -10 questionnaire to measure stress level. Glucometer was used for checking the random blood sugar levels. Chi-Square test was used to determine the relationship between the two variables, results from 39 respondents who had moderate stress levels, 27 respondents had high blood sugar levels of 23 (85.2%) and mild stress levels as many as 12 respondents with normal blood sugar levels 7 (58.3); There is a correlation between stress and random blood sugar levels in Secondary Learning Recognition (RPL) students of the Nursing Department Class II at Health Polytechnic of Palangka Raya with ? value <0.005.


2020 ◽  
Vol 9 (3) ◽  
pp. 267
Author(s):  
Jujuk Proboningsih ◽  
Anita Joeliantina ◽  
Aida Novitasari ◽  
Dewi Purnamawati

Diabetes mellitus is a chronic disease that requires long-term management. There is a tendency in type 2 diabetes mellitus patients to use herbs as a complement to medical treatment. The purpose of this study was to analyze the use of herbs as a complement to medical treatment in reducing blood sugar levels of T2DM patients. This type of research is quasi-experimental, with 40 research subjects divided into 4 groups. Determination of research subjects by purposive sampling in accordance with established inclusion criteria. Data analysis using paired T test. The majority of respondents was women (77.5%) and had no genetic history (75%). The duration of type 2 diabetes mellitus  majority was &gt;5 years 72.5%). Data on random blood sugar levels before (p=0.098) and after (p=0.113) intervention were normally distributed and homogeneous p&gt;0.05 (0.839). The treatment group (groups 2, 3, and 4) showed a significant decrease in random blood sugar levels as the control group (1) with a significance value &lt;0.05. Giving herbs has a tendency to reduce random blood sugar levels when used as a complement to medical treatment. Bitter melon shows the effect of decreasing random blood sugar levels greater than the provision of bay leaves and cinnamon.<br /><br />


2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Adriansyah L. Putra ◽  
Pemsi M. Wowor ◽  
Herlina I. S. Wungouw

Abstract: Blood sugar or blood glucose is a universal fuel for human cells and functioning as the source of carbon for the synthesis of many other compounds. As the globalization causes changes of lifestyle that tend be unhealthy lifestyle, there is a need for early detection of blood sugar level since adolescence. This was a descriptive study with a cross sectional design. This study aimed to obtain the random blood sugar levels among college students at Medical Faculty of Sam Ratulangi University Manado. The result showed that of 51 subjects, at age 17, 5 (9.8%) had low blood sugar level and 5 (9,8%) had normal blood sugar level. At age 18, 2 students (3.9%) had low blood sugar level and 24 (47.1%) had normal blood sugar level. At age of 19, 2 students (9,8%) had low blood sugar level and 13 (25.5%) had normal blood sugar level. Of 24 male students, 19 (37.3%) had normal blood sugar level and 5 (9.8%) had low blood sugar level. Of 27 female students, 23 (45.1%) had normal blood sugar level meanwhile 4 (7.8%) had low blood sugar level.Keywords: blood sugar, studentsAbstrak: Gula darah atau glukosa darah merupakan bahan bakar universal bagi sel-sel tubuh manusia dan berfungsi sebagai sumber karbon untuk sintesis sebagian besar senyawa lainnya. Seiring arus globalisasi menyebabkan terjadinya perubahan pola hidup yang cenderung mengacu pada gaya hidup tidak sehat maka diperlukan deteksi dini gula darah sejak remaja. Penelitian ini menggunakan metode deskriptif dengan desain potong lintang. Penelitian ini bertujuan untuk mengetahui kadar gula darah sewaktu pada mahasiswa angkatan 2015 Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sam Ratulangi Manado. Hasil penelitian menunjukkan bahwa dari 51 subyek penelitian, pada usia 17 tahun 5 orang (9,8%) dengan kadar gula rendah dan 5 orang (9,8%) dengan kadar gula darah normal. Pada usia 18 tahun diperoleh 2 orang (3,9%) dengan kadar gula rendah dan 24 orang (47,1%) dengan kadar gula darah normal. Pada usia 19 tahun diperoleh 2 orang dengan kadar gula rendah (9,8%) dan 13 orang dengan gula darah normal (25,5%). Dari 24 subyek laki-laki, 19 (37,3%) memiliki kadar gula normal dan 5 (9,8%) memiliki kadar gula darah rendah. Dari 27 subyek perempuan, 23 (45,1%) memiliki kadar gula normal dan 4 (7,8%) memiliki kadar gula darah rendah.Kata kunci: gula darah, mahasiswa


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